{"id":"https://openalex.org/W2017101335","doi":"https://doi.org/10.1007/s10517-008-0287-z","title":"Ultrastructural signs of cyclophosphamide-induced damage to cardiomyocytes","display_name":"Ultrastructural signs of cyclophosphamide-induced damage to cardiomyocytes","publication_year":2008,"publication_date":"2008-09-01","ids":{"openalex":"https://openalex.org/W2017101335","doi":"https://doi.org/10.1007/s10517-008-0287-z","mag":"2017101335","pmid":"https://pubmed.ncbi.nlm.nih.gov/19240862"},"language":"en","primary_location":{"id":"doi:10.1007/s10517-008-0287-z","doi":"https://doi.org/10.1007/s10517-008-0287-z","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10517-008-0287-z","pdf_url":null,"source":{"id":"https://openalex.org/S141734485","display_name":"Bulletin of Experimental Biology and Medicine","issn_l":"0007-4888","issn":["0007-4888","0365-9615","1573-8221","2413-1008"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-1","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bulletin of Experimental Biology and Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087166684","display_name":"Elena L. Lushnikova","orcid":"https://orcid.org/0000-0002-3269-2465","observed_orcids":["https://orcid.org/0000-0002-3269-2465"]},"institutions":[{"id":"https://openalex.org/I4210128002","display_name":"Institute of Molecular Pathology and Pathomorphology","ror":"https://ror.org/02trrjx85","country_code":"RU","type":"facility","lineage":["https://openalex.org/I4210128002"]}],"countries":["RU"],"is_corresponding":true,"raw_author_name":"E. L. Lushnikova","raw_affiliation_strings":["Institute of Regional Pathology and Pathomorphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia. pathol@soramn.ru","Siberian Division of the Russian Academy of Medical Sciences"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Regional Pathology and Pathomorphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia. pathol@soramn.ru","institution_ids":["https://openalex.org/I4210128002"]},{"raw_affiliation_string":"Siberian Division of the Russian Academy of Medical Sciences","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056285231","display_name":"L. M. Nepomnyashchikh","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L. M. Nepomnyashchikh","raw_affiliation_strings":["Institute of Regional Pathology and Pathomorphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia","Siberian Division of the Russian Academy of Medical Sciences"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Regional Pathology and Pathomorphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia","institution_ids":[]},{"raw_affiliation_string":"Siberian Division of the Russian Academy of Medical Sciences","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084263965","display_name":"E. A. Sviridov","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E. A. Sviridov","raw_affiliation_strings":["Institute of Regional Pathology and Pathomorphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia","Siberian Division of the Russian Academy of Medical Sciences"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Regional Pathology and Pathomorphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia","institution_ids":[]},{"raw_affiliation_string":"Siberian Division of the Russian Academy of Medical Sciences","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005986779","display_name":"\u041a\u043b\u0438\u043d\u043d\u0438\u043a\u043e\u0432\u0430 \u041c\u0430\u0440\u0438\u043d\u0430 \u0413\u0435\u043d\u043d\u0430\u0434\u044c\u0435\u0432\u043d\u0430","orcid":"https://orcid.org/0009-0008-5508-0411","observed_orcids":["https://orcid.org/0009-0008-5508-0411","https://orcid.org/0000-0001-9909-5027"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. G. Klinnikova","raw_affiliation_strings":["Institute of Regional Pathology and Pathomorphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia","Siberian Division of the Russian Academy of Medical Sciences"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Regional Pathology and Pathomorphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia","institution_ids":[]},{"raw_affiliation_string":"Siberian Division of the Russian Academy of Medical Sciences","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5087166684"],"corresponding_institution_ids":["https://openalex.org/I4210128002"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"146","issue":"3","first_page":"366","last_page":"371"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11535","display_name":"Chemotherapy-induced cardiotoxicity and mitigation","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11535","display_name":"Chemotherapy-induced cardiotoxicity and mitigation","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.002099999925121665,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14072","display_name":"Immunotoxicology and immune responses","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cyclophosphamide","display_name":"cyclophosphamide","score":0.9959999918937683},{"id":"https://openalex.org/keywords/cardiotoxicity","display_name":"cardiotoxicity","score":0.9700000286102295},{"id":"https://openalex.org/keywords/cardiomyocytes","display_name":"cardiomyocytes","score":0.9629999995231628},{"id":"https://openalex.org/keywords/ultrastructure","display_name":"ultrastructure","score":0.7289999723434448},{"id":"https://openalex.org/keywords/sarcoplasmic-reticulum","display_name":"sarcoplasmic reticulum","score":0.9700000286102295},{"id":"https://openalex.org/keywords/mitochondrial-damage","display_name":"mitochondrial damage","score":0.7829999923706055},{"id":"https://openalex.org/keywords/nuclear-membrane-invaginations","display_name":"nuclear membrane invaginations","score":0.8939999938011169},{"id":"https://openalex.org/keywords/nuclear-translocation","display_name":"nuclear translocation","score":0.675000011920929},{"id":"https://openalex.org/keywords/rats","display_name":"rats","score":0.3149999976158142}],"concepts":[{"id":"https://openalex.org/C87555872","wikidata":"https://www.wikidata.org/wiki/Q3141316","display_name":"Ultrastructure","level":2,"score":0.8341209888458252},{"id":"https://openalex.org/C158617107","wikidata":"https://www.wikidata.org/wiki/Q79927","display_name":"Endoplasmic reticulum","level":2,"score":0.7087900638580322},{"id":"https://openalex.org/C2776755627","wikidata":"https://www.wikidata.org/wiki/Q408524","display_name":"Cyclophosphamide","level":3,"score":0.5196812748908997},{"id":"https://openalex.org/C7301908","wikidata":"https://www.wikidata.org/wiki/Q318623","display_name":"Myofibril","level":2,"score":0.5131121873855591},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.48552370071411133},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.4433441162109375},{"id":"https://openalex.org/C2778609137","wikidata":"https://www.wikidata.org/wiki/Q105790271","display_name":"Myelin","level":3,"score":0.43510836362838745},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3740383982658386},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.357405424118042},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.32242387533187866},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.1563492715358734},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.13821735978126526},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.10677704215049744},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.08013260364532471},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.059385091066360474},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003520","descriptor_name":"Cyclophosphamide","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009210","descriptor_name":"Myofibrils","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009210","descriptor_name":"Myofibrils","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D032383","descriptor_name":"Myocytes, Cardiac","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D032383","descriptor_name":"Myocytes, Cardiac","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/s10517-008-0287-z","doi":"https://doi.org/10.1007/s10517-008-0287-z","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10517-008-0287-z","pdf_url":null,"source":{"id":"https://openalex.org/S141734485","display_name":"Bulletin of Experimental Biology and Medicine","issn_l":"0007-4888","issn":["0007-4888","0365-9615","1573-8221","2413-1008"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-1","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bulletin of Experimental Biology and Medicine","raw_type":"journal-article"},{"id":"pmid:19240862","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19240862","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bulletin of experimental biology and medicine","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W1935077308","https://openalex.org/W1970997012","https://openalex.org/W1973415616","https://openalex.org/W2034332201","https://openalex.org/W2039920784","https://openalex.org/W2058991856","https://openalex.org/W2142399979","https://openalex.org/W2168847627","https://openalex.org/W2169165039"],"related_works":["https://openalex.org/W2471345177","https://openalex.org/W2054548181","https://openalex.org/W4396578517","https://openalex.org/W2039920784","https://openalex.org/W1997784207","https://openalex.org/W2472017277","https://openalex.org/W2418781048","https://openalex.org/W2166357789","https://openalex.org/W4205317429","https://openalex.org/W2403244882"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}