{"id":"https://openalex.org/W2017054633","doi":"https://doi.org/10.4155/cli.14.62","title":"HER2/neu: an increasingly important therapeutic target. Part 2: Distribution of HER2/neu overexpression and gene amplification by organ, tumor site and histology","display_name":"HER2/neu: an increasingly important therapeutic target. Part 2: Distribution of HER2/neu overexpression and gene amplification by organ, tumor site and histology","publication_year":2014,"publication_date":"2014-08-01","ids":{"openalex":"https://openalex.org/W2017054633","doi":"https://doi.org/10.4155/cli.14.62","mag":"2017054633"},"language":"en","primary_location":{"id":"doi:10.4155/cli.14.62","doi":"https://doi.org/10.4155/cli.14.62","is_oa":false,"landing_page_url":"https://doi.org/10.4155/cli.14.62","pdf_url":null,"source":{"id":"https://openalex.org/S2765044866","display_name":"Clinical Investigation","issn_l":"2041-6792","issn":["2041-6792","2041-6806"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320466","host_organization_name":"OMICS Publishing Group","host_organization_lineage":["https://openalex.org/P4310320466"],"host_organization_lineage_names":["OMICS Publishing Group"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Investigation","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://escholarship.org/uc/item/8kb0k91z","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086973652","display_name":"Edward L. Nelson","orcid":"https://orcid.org/0000-0001-7887-032X","observed_orcids":["https://orcid.org/0000-0001-7887-032X"]},"institutions":[{"id":"https://openalex.org/I204250578","display_name":"University of California, Irvine","ror":"https://ror.org/04gyf1771","country_code":"US","type":"education","lineage":["https://openalex.org/I204250578"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Edward L Nelson","raw_affiliation_strings":["School of Medicine; Division of Hematology/Oncology; Department of Medicine; Department of Molecular Biology & Biochemistry; Sprague Hall, Irvine, CA 92697, USA","UC Irvine UC Irvine","University of California, Irvine,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Medicine; Division of Hematology/Oncology; Department of Medicine; Department of Molecular Biology & Biochemistry; Sprague Hall, Irvine, CA 92697, USA","institution_ids":["https://openalex.org/I204250578"]},{"raw_affiliation_string":"UC Irvine UC Irvine","institution_ids":["https://openalex.org/I204250578"]},{"raw_affiliation_string":"University of California, Irvine,","institution_ids":["https://openalex.org/I204250578"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5086973652"],"corresponding_institution_ids":["https://openalex.org/I204250578"],"apc_list":null,"apc_paid":null,"fwci":0.4521,"has_fulltext":true,"cited_by_count":12,"citation_normalized_percentile":{"value":0.64329481,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"4","issue":"8","first_page":"705","last_page":"728"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10755","display_name":"HER2/EGFR in Cancer Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10755","display_name":"HER2/EGFR in Cancer Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10417","display_name":"Lung Cancer Treatments and Mutations","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10696","display_name":"Gastric Cancer Management and Outcomes","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/her2-neu","display_name":"HER2/neu","score":1.0},{"id":"https://openalex.org/keywords/c-erbb-2","display_name":"c-erbB-2","score":0.8870000243186951},{"id":"https://openalex.org/keywords/her2-overexpression","display_name":"HER2 overexpression","score":0.824999988079071},{"id":"https://openalex.org/keywords/gene-amplification","display_name":"gene amplification","score":0.8849999904632568},{"id":"https://openalex.org/keywords/tumor-site-distribution","display_name":"tumor site distribution","score":0.7590000033378601},{"id":"https://openalex.org/keywords/histology","display_name":"histology","score":0.6639999747276306},{"id":"https://openalex.org/keywords/her2-targeted-therapy","display_name":"HER2-targeted therapy","score":0.8080000281333923},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.6110000014305115},{"id":"https://openalex.org/keywords/gastric-cancer","display_name":"gastric cancer","score":0.5249999761581421},{"id":"https://openalex.org/keywords/lung-cancer","display_name":"lung cancer","score":0.3700000047683716}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7288640141487122},{"id":"https://openalex.org/C2776872082","wikidata":"https://www.wikidata.org/wiki/Q181874","display_name":"HER2/neu","level":4,"score":0.49502772092819214},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3891354501247406},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.35017484426498413},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3205331563949585},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2862386107444763},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.22674468159675598},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.14963343739509583},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.14390605688095093}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.4155/cli.14.62","doi":"https://doi.org/10.4155/cli.14.62","is_oa":false,"landing_page_url":"https://doi.org/10.4155/cli.14.62","pdf_url":null,"source":{"id":"https://openalex.org/S2765044866","display_name":"Clinical Investigation","issn_l":"2041-6792","issn":["2041-6792","2041-6806"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320466","host_organization_name":"OMICS Publishing Group","host_organization_lineage":["https://openalex.org/P4310320466"],"host_organization_lineage_names":["OMICS Publishing Group"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Investigation","raw_type":"journal-article"},{"id":"pmh:oai:escholarship.org/ark:/13030/qt8kb0k91z","doi":null,"is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/8kb0k91z","pdf_url":"https://escholarship.org/uc/item/8kb0k91z","source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"article"},{"id":"pmh:qt8kb0k91z","doi":null,"is_oa":true,"landing_page_url":"http://www.escholarship.org/uc/item/8kb0k91z","pdf_url":"http://www.escholarship.org/uc/item/8kb0k91z","source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nelson, EL; &amp; Nelson, E. (2014). An increasingly important therapeutic target: Part 2 Distribution of HER2/neu Overexpression and Gene Amplification by Organ, Tumor Site and Histology. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/8kb0k91z","raw_type":"article"},{"id":"pmh:oai:escholarship.org/ark:/13030/qt1tn444mg","doi":null,"is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/1tn444mg","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"article"},{"id":"pmh:oai:escholarship.org:ark:/13030/qt1tn444mg","doi":null,"is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/1tn444mg","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Clinical Investigation, vol 4, iss 8","raw_type":"article"},{"id":"pmh:qt1tn444mg","doi":null,"is_oa":true,"landing_page_url":"http://www.escholarship.org/uc/item/1tn444mg","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nelson, EL. (2014). HER2/neu:An Increasingly Important Therapeutic Target: Part 2 Distribution of HER2/neu Overexpression and Gene Amplification by Organ, Tumor Site and Histology.. Clinical Investigation. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/1tn444mg","raw_type":"article"}],"best_oa_location":{"id":"pmh:oai:escholarship.org/ark:/13030/qt8kb0k91z","doi":null,"is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/8kb0k91z","pdf_url":"https://escholarship.org/uc/item/8kb0k91z","source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2017054633.pdf","grobid_xml":"https://content.openalex.org/works/W2017054633.grobid-xml"},"referenced_works_count":468,"referenced_works":["https://openalex.org/W8106285","https://openalex.org/W17859455","https://openalex.org/W21899765","https://openalex.org/W21933366","https://openalex.org/W27726180","https://openalex.org/W45711525","https://openalex.org/W100230321","https://openalex.org/W101171352","https://openalex.org/W109710750","https://openalex.org/W119518076","https://openalex.org/W139557207","https://openalex.org/W155652442","https://openalex.org/W158850611","https://openalex.org/W161063278","https://openalex.org/W167009972","https://openalex.org/W180715779","https://openalex.org/W181789739","https://openalex.org/W226177266","https://openalex.org/W272752578","https://openalex.org/W1268608731","https://openalex.org/W1482931163","https://openalex.org/W1484448739","https://openalex.org/W1502854409","https://openalex.org/W1507354864","https://openalex.org/W1516974032","https://openalex.org/W1524400131","https://openalex.org/W1552550535","https://openalex.org/W1554743435","https://openalex.org/W1556523892","https://openalex.org/W1559733556","https://openalex.org/W1560003193","https://openalex.org/W1561346937","https://openalex.org/W1566258185","https://openalex.org/W1572880308","https://openalex.org/W1580523172","https://openalex.org/W1595038913","https://openalex.org/W1613075622","https://openalex.org/W1714197903","https://openalex.org/W1742822977","https://openalex.org/W1763922672","https://openalex.org/W1798073226","https://openalex.org/W1800916217","https://openalex.org/W1829218290","https://openalex.org/W1850322463","https://openalex.org/W1890809256","https://openalex.org/W1915522638","https://openalex.org/W1940969361","https://openalex.org/W1942570265","https://openalex.org/W1943696496","https://openalex.org/W1947442001","https://openalex.org/W1954085239","https://openalex.org/W1957044910","https://openalex.org/W1964280684","https://openalex.org/W1964636300","https://openalex.org/W1965464966","https://openalex.org/W1965729473","https://openalex.org/W1965850768","https://openalex.org/W1966469997","https://openalex.org/W1966598152","https://openalex.org/W1966668892","https://openalex.org/W1966854177","https://openalex.org/W1966890968","https://openalex.org/W1967005016","https://openalex.org/W1967210522","https://openalex.org/W1967760337","https://openalex.org/W1968007824","https://openalex.org/W1968881689","https://openalex.org/W1968989154","https://openalex.org/W1970019155","https://openalex.org/W1970232026","https://openalex.org/W1970892266","https://openalex.org/W1970901810","https://openalex.org/W1971381959","https://openalex.org/W1972085092","https://openalex.org/W1972692320","https://openalex.org/W1972878967","https://openalex.org/W1972931463","https://openalex.org/W1973134510","https://openalex.org/W1973460244","https://openalex.org/W1974260910","https://openalex.org/W1975240042","https://openalex.org/W1975602357","https://openalex.org/W1976381106","https://openalex.org/W1977278230","https://openalex.org/W1978082129","https://openalex.org/W1979016735","https://openalex.org/W1979488703","https://openalex.org/W1982637165","https://openalex.org/W1982849486","https://openalex.org/W1984424436","https://openalex.org/W1985827132","https://openalex.org/W1985979457","https://openalex.org/W1986028009","https://openalex.org/W1986533238","https://openalex.org/W1986801058","https://openalex.org/W1987009448","https://openalex.org/W1988066147","https://openalex.org/W1988976538","https://openalex.org/W1990291331","https://openalex.org/W1990407963","https://openalex.org/W1990774346","https://openalex.org/W1990836895","https://openalex.org/W1991341116","https://openalex.org/W1992201133","https://openalex.org/W1992459095","https://openalex.org/W1992752045","https://openalex.org/W1992825314","https://openalex.org/W1994185611","https://openalex.org/W1994719068","https://openalex.org/W1996202512","https://openalex.org/W1996646886","https://openalex.org/W1997277149","https://openalex.org/W1997602199","https://openalex.org/W1997800869","https://openalex.org/W1997855715","https://openalex.org/W1998737062","https://openalex.org/W1999828947","https://openalex.org/W2000186289","https://openalex.org/W2001065504","https://openalex.org/W2001419870","https://openalex.org/W2001791004","https://openalex.org/W2001868613","https://openalex.org/W2002732684","https://openalex.org/W2003173259","https://openalex.org/W2003905042","https://openalex.org/W2006745678","https://openalex.org/W2007078652","https://openalex.org/W2007191543","https://openalex.org/W2007784773","https://openalex.org/W2008531855","https://openalex.org/W2008678746","https://openalex.org/W2008865737","https://openalex.org/W2010705441","https://openalex.org/W2010862284","https://openalex.org/W2011028805","https://openalex.org/W2011204628","https://openalex.org/W2011469023","https://openalex.org/W2011945440","https://openalex.org/W2012375478","https://openalex.org/W2012572051","https://openalex.org/W2012643120","https://openalex.org/W2013475082","https://openalex.org/W2013811085","https://openalex.org/W2013882707","https://openalex.org/W2014274347","https://openalex.org/W2014538286","https://openalex.org/W2014711201","https://openalex.org/W2014718912","https://openalex.org/W2015143670","https://openalex.org/W2015349238","https://openalex.org/W2015376103","https://openalex.org/W2015556441","https://openalex.org/W2015723871","https://openalex.org/W2015725869","https://openalex.org/W2016142664","https://openalex.org/W2016315267","https://openalex.org/W2016524281","https://openalex.org/W2017030359","https://openalex.org/W2017211343","https://openalex.org/W2017600905","https://openalex.org/W2018149997","https://openalex.org/W2018271790","https://openalex.org/W2019267750","https://openalex.org/W2019488523","https://openalex.org/W2020583055","https://openalex.org/W2022151104","https://openalex.org/W2023355039","https://openalex.org/W2023958685","https://openalex.org/W2024177665","https://openalex.org/W2024236684","https://openalex.org/W2024638927","https://openalex.org/W2025070867","https://openalex.org/W2025394348","https://openalex.org/W2025464344","https://openalex.org/W2025731174","https://openalex.org/W2028153418","https://openalex.org/W2028686154","https://openalex.org/W2028837881","https://openalex.org/W2028914343","https://openalex.org/W2029330089","https://openalex.org/W2029370619","https://openalex.org/W2029717521","https://openalex.org/W2029740942","https://openalex.org/W2030032444","https://openalex.org/W2030807319","https://openalex.org/W2033586758","https://openalex.org/W2033748688","https://openalex.org/W2033866684","https://openalex.org/W2034016702","https://openalex.org/W2035386351","https://openalex.org/W2035880722","https://openalex.org/W2036102152","https://openalex.org/W2036315480","https://openalex.org/W2036589190","https://openalex.org/W2038081635","https://openalex.org/W2038313712","https://openalex.org/W2038846160","https://openalex.org/W2038969587","https://openalex.org/W2039241242","https://openalex.org/W2040260667","https://openalex.org/W2041225958","https://openalex.org/W2041254255","https://openalex.org/W2041331415","https://openalex.org/W2041919461","https://openalex.org/W2042051621","https://openalex.org/W2042190557","https://openalex.org/W2042214171","https://openalex.org/W2042378775","https://openalex.org/W2042471142","https://openalex.org/W2042660364","https://openalex.org/W2044365382","https://openalex.org/W2044576449","https://openalex.org/W2044930054","https://openalex.org/W2045220494","https://openalex.org/W2045297830","https://openalex.org/W2045471398","https://openalex.org/W2045508611","https://openalex.org/W2046050735","https://openalex.org/W2046180857","https://openalex.org/W2046393549","https://openalex.org/W2046551180","https://openalex.org/W2046640268","https://openalex.org/W2046793599","https://openalex.org/W2047315585","https://openalex.org/W2047411533","https://openalex.org/W2048001157","https://openalex.org/W2048623699","https://openalex.org/W2049273954","https://openalex.org/W2049449785","https://openalex.org/W2050131716","https://openalex.org/W2051856430","https://openalex.org/W2052365599","https://openalex.org/W2054244076","https://openalex.org/W2054740993","https://openalex.org/W2055306626","https://openalex.org/W2056153736","https://openalex.org/W2057046322","https://openalex.org/W2057097544","https://openalex.org/W2058685264","https://openalex.org/W2058836795","https://openalex.org/W2059814855","https://openalex.org/W2060084543","https://openalex.org/W2062872060","https://openalex.org/W2063375330","https://openalex.org/W2063549151","https://openalex.org/W2064303598","https://openalex.org/W2064977167","https://openalex.org/W2065717159","https://openalex.org/W2065965795","https://openalex.org/W2067366149","https://openalex.org/W2068404256","https://openalex.org/W2068828511","https://openalex.org/W2069094027","https://openalex.org/W2071164914","https://openalex.org/W2071212581","https://openalex.org/W2071289226","https://openalex.org/W2071453915","https://openalex.org/W2071631616","https://openalex.org/W2071751238","https://openalex.org/W2071901713","https://openalex.org/W2072068836","https://openalex.org/W2072811682","https://openalex.org/W2073323418","https://openalex.org/W2074470290","https://openalex.org/W2074725242","https://openalex.org/W2074961178","https://openalex.org/W2075657881","https://openalex.org/W2075879923","https://openalex.org/W2075883741","https://openalex.org/W2076097510","https://openalex.org/W2076325662","https://openalex.org/W2076371373","https://openalex.org/W2077263403","https://openalex.org/W2077363843","https://openalex.org/W2077545099","https://openalex.org/W2078528550","https://openalex.org/W2078588003","https://openalex.org/W2078942394","https://openalex.org/W2079516803","https://openalex.org/W2079879369","https://openalex.org/W2080384716","https://openalex.org/W2081292070","https://openalex.org/W2081833121","https://openalex.org/W2082798082","https://openalex.org/W2082844220","https://openalex.org/W2083821453","https://openalex.org/W2083997119","https://openalex.org/W2084206700","https://openalex.org/W2084220146","https://openalex.org/W2084448322","https://openalex.org/W2084520181","https://openalex.org/W2085800326","https://openalex.org/W2086209079","https://openalex.org/W2086478541","https://openalex.org/W2087756121","https://openalex.org/W2088254697","https://openalex.org/W2088378462","https://openalex.org/W2089487481","https://openalex.org/W2089757606","https://openalex.org/W2089973951","https://openalex.org/W2090038674","https://openalex.org/W2090039904","https://openalex.org/W2091054495","https://openalex.org/W2091245071","https://openalex.org/W2091682267","https://openalex.org/W2091784724","https://openalex.org/W2092342047","https://openalex.org/W2093189266","https://openalex.org/W2093273279","https://openalex.org/W2093438644","https://openalex.org/W2093858263","https://openalex.org/W2094222567","https://openalex.org/W2094846142","https://openalex.org/W2095210894","https://openalex.org/W2099139945","https://openalex.org/W2099421298","https://openalex.org/W2099741731","https://openalex.org/W2102171632","https://openalex.org/W2104670195","https://openalex.org/W2105023567","https://openalex.org/W2107460962","https://openalex.org/W2107474176","https://openalex.org/W2107562400","https://openalex.org/W2107601683","https://openalex.org/W2108428761","https://openalex.org/W2108523633","https://openalex.org/W2109125167","https://openalex.org/W2109934093","https://openalex.org/W2111202034","https://openalex.org/W2112750808","https://openalex.org/W2113627981","https://openalex.org/W2113905713","https://openalex.org/W2116152465","https://openalex.org/W2116555647","https://openalex.org/W2117942877","https://openalex.org/W2118490584","https://openalex.org/W2119244587","https://openalex.org/W2119909440","https://openalex.org/W2120178047","https://openalex.org/W2120840548","https://openalex.org/W2121516394","https://openalex.org/W2122434179","https://openalex.org/W2123620222","https://openalex.org/W2123980755","https://openalex.org/W2124394191","https://openalex.org/W2124614008","https://openalex.org/W2124845837","https://openalex.org/W2125591289","https://openalex.org/W2125677057","https://openalex.org/W2125730396","https://openalex.org/W2126816162","https://openalex.org/W2128816893","https://openalex.org/W2128904109","https://openalex.org/W2130043727","https://openalex.org/W2130404651","https://openalex.org/W2130479718","https://openalex.org/W2131931560","https://openalex.org/W2135990563","https://openalex.org/W2136701318","https://openalex.org/W2138213235","https://openalex.org/W2139995230","https://openalex.org/W2141393790","https://openalex.org/W2142076829","https://openalex.org/W2142851253","https://openalex.org/W2143618467","https://openalex.org/W2143668948","https://openalex.org/W2143913849","https://openalex.org/W2144958249","https://openalex.org/W2145640226","https://openalex.org/W2146269515","https://openalex.org/W2147065831","https://openalex.org/W2148522609","https://openalex.org/W2148838030","https://openalex.org/W2149152398","https://openalex.org/W2150022366","https://openalex.org/W2150516428","https://openalex.org/W2151453176","https://openalex.org/W2151605875","https://openalex.org/W2151926043","https://openalex.org/W2152113072","https://openalex.org/W2152936136","https://openalex.org/W2154086342","https://openalex.org/W2155275416","https://openalex.org/W2155475018","https://openalex.org/W2155996796","https://openalex.org/W2156095111","https://openalex.org/W2156708022","https://openalex.org/W2157301873","https://openalex.org/W2158721393","https://openalex.org/W2158797807","https://openalex.org/W2159363679","https://openalex.org/W2159681737","https://openalex.org/W2159698605","https://openalex.org/W2160308307","https://openalex.org/W2161232022","https://openalex.org/W2161355896","https://openalex.org/W2161589433","https://openalex.org/W2162590515","https://openalex.org/W2162629415","https://openalex.org/W2163330751","https://openalex.org/W2163641589","https://openalex.org/W2163947995","https://openalex.org/W2164486810","https://openalex.org/W2164572775","https://openalex.org/W2165534156","https://openalex.org/W2166257353","https://openalex.org/W2168785527","https://openalex.org/W2168859271","https://openalex.org/W2169782526","https://openalex.org/W2169845291","https://openalex.org/W2170484275","https://openalex.org/W2171817832","https://openalex.org/W2172118845","https://openalex.org/W2172415884","https://openalex.org/W2185592773","https://openalex.org/W2202959459","https://openalex.org/W2222382372","https://openalex.org/W2232558221","https://openalex.org/W2249571958","https://openalex.org/W2255510131","https://openalex.org/W2257465599","https://openalex.org/W2264655007","https://openalex.org/W2276418696","https://openalex.org/W2288791710","https://openalex.org/W2331628152","https://openalex.org/W2333987823","https://openalex.org/W2334343715","https://openalex.org/W2340286967","https://openalex.org/W2394827078","https://openalex.org/W2395350983","https://openalex.org/W2397089394","https://openalex.org/W2397097124","https://openalex.org/W2398166106","https://openalex.org/W2398534157","https://openalex.org/W2400288989","https://openalex.org/W2406509964","https://openalex.org/W2408927291","https://openalex.org/W2409683476","https://openalex.org/W2409821120","https://openalex.org/W2410245378","https://openalex.org/W2411312370","https://openalex.org/W2411799325","https://openalex.org/W2412303581","https://openalex.org/W2412779137","https://openalex.org/W2414514378","https://openalex.org/W2415035660","https://openalex.org/W2415644022","https://openalex.org/W2415957093","https://openalex.org/W2416782477","https://openalex.org/W2417322313","https://openalex.org/W2418016175","https://openalex.org/W2418347202","https://openalex.org/W2420660738","https://openalex.org/W2424915846","https://openalex.org/W2426196179","https://openalex.org/W2433828214","https://openalex.org/W2437242637","https://openalex.org/W2438480115","https://openalex.org/W2442875744","https://openalex.org/W2462332024","https://openalex.org/W2471050000","https://openalex.org/W2471393025","https://openalex.org/W2471860058","https://openalex.org/W2472794159","https://openalex.org/W2472876846","https://openalex.org/W2479171025","https://openalex.org/W2969657370","https://openalex.org/W4247823004"],"related_works":["https://openalex.org/W7001040144","https://openalex.org/W1981398177","https://openalex.org/W2084520181","https://openalex.org/W2767660897","https://openalex.org/W7000840000","https://openalex.org/W2095408631","https://openalex.org/W7220865693","https://openalex.org/W81865859","https://openalex.org/W2229546226","https://openalex.org/W2051975891"],"abstract_inverted_index":{"No":[0],"biological":[1],"molecule":[2],"in":[3,82],"the":[4,20,23,28,36,67,75,102],"field":[5],"of":[6,22,30,35,42,45,77,98,104],"oncology":[7],"has":[8],"been":[9],"more":[10,13],"extensively":[11],"or":[12],"successfully":[14],"targeted":[15],"for":[16,38,95],"therapeutic":[17,40,110],"intent":[18],"than":[19],"product":[21],"c-erbB2":[24],"gene,":[25],"HER2/neu.This":[26],"is":[27],"second":[29],"a":[31,64],"comprehensive":[32,87],"three-part":[33],"review":[34],"foundation":[37],"and":[39,55,61,74,92],"targeting":[41],"HER2/neu.The":[43],"distribution":[44],"HER2/neu":[46,105],"overexpression":[47],"and/or":[48],"gene":[49],"amplification":[50],"by":[51],"individual":[52],"tumor":[53],"sites":[54],"histologies":[56],"will":[57,89],"be":[58],"comprehensively":[59],"surveyed":[60],"described.This":[62],"provides":[63],"bridge":[65],"between":[66],"primarily":[68],"basic":[69],"science":[70],"focused":[71],"Part":[72,83],"I,":[73],"survey":[76,88],"clinical":[78],"applications":[79],"to":[80],"follow":[81],"III.In":[84],"combination,":[85],"this":[86],"identify":[90],"opportunities":[91],"promising":[93],"areas":[94],"future":[96],"evaluation":[97],"HER2/neu-targeted":[99],"therapies,":[100],"highlighting":[101],"importance":[103],"as":[106],"an":[107],"increasingly":[108],"important":[109],"target.":[111]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
