{"id":"https://openalex.org/W2017035597","doi":"https://doi.org/10.1016/s0378-1119(99)00295-4","title":"Mitochondrial DNA variation in human evolution and disease","display_name":"Mitochondrial DNA variation in human evolution and disease","publication_year":1999,"publication_date":"1999-09-01","ids":{"openalex":"https://openalex.org/W2017035597","doi":"https://doi.org/10.1016/s0378-1119(99)00295-4","mag":"2017035597","pmid":"https://pubmed.ncbi.nlm.nih.gov/10570998"},"language":"en","primary_location":{"id":"doi:10.1016/s0378-1119(99)00295-4","doi":"https://doi.org/10.1016/s0378-1119(99)00295-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0378-1119(99)00295-4","pdf_url":null,"source":{"id":"https://openalex.org/S75702506","display_name":"Gene","issn_l":"0378-1119","issn":["0378-1119","1879-0038"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gene","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085274471","display_name":"Douglas C. Wallace","orcid":"https://orcid.org/0000-0002-7480-8278","observed_orcids":["https://orcid.org/0000-0002-7480-8278"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Douglas C. Wallace","raw_affiliation_strings":["Center for Molecular Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA","Center for Molecular Medicine, Emory University School of Medicine, 1462 Clifton Rd., Atlanta, GA 30322, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Molecular Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Center for Molecular Medicine, Emory University School of Medicine, 1462 Clifton Rd., Atlanta, GA 30322, USA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Michael D. Brown","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael D. Brown","raw_affiliation_strings":["Center for Molecular Medicine, Emory University School of Medicine, 1462 Clifton Rd., Atlanta, GA 30322, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Molecular Medicine, Emory University School of Medicine, 1462 Clifton Rd., Atlanta, GA 30322, USA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5032518195","display_name":"Marie T. Lott","orcid":"https://orcid.org/0000-0003-2035-479X","observed_orcids":["https://orcid.org/0000-0003-2035-479X"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marie T. Lott","raw_affiliation_strings":["Center for Molecular Medicine, Emory University School of Medicine, 1462 Clifton Rd., Atlanta, GA 30322, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Molecular Medicine, Emory University School of Medicine, 1462 Clifton Rd., Atlanta, GA 30322, USA","institution_ids":["https://openalex.org/I150468666"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5085274471"],"corresponding_institution_ids":["https://openalex.org/I150468666"],"apc_list":{"value":3300,"currency":"USD","value_usd":3300},"apc_paid":null,"fwci":1.7021,"has_fulltext":false,"cited_by_count":461,"citation_normalized_percentile":{"value":0.83713851,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"238","issue":"1","first_page":"211","last_page":"230"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10751","display_name":"Forensic and Genetic Research","score":0.9818999767303467,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10751","display_name":"Forensic and Genetic Research","score":0.9818999767303467,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.01080000028014183,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10012","display_name":"Genetic diversity and population structure","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mitochondrial-dna-variation","display_name":"mitochondrial DNA variation","score":0.9589999914169312},{"id":"https://openalex.org/keywords/human-evolution","display_name":"human evolution","score":0.949999988079071},{"id":"https://openalex.org/keywords/human-migration","display_name":"human migration","score":0.5770000219345093},{"id":"https://openalex.org/keywords/out-of-africa-migration","display_name":"out-of-Africa migration","score":0.6069999933242798},{"id":"https://openalex.org/keywords/leber-hereditary-optic-neuropathy","display_name":"Leber's hereditary optic neuropathy","score":0.8389999866485596},{"id":"https://openalex.org/keywords/mtdna-mutations","display_name":"mitochondrial DNA mutations","score":0.7699999809265137},{"id":"https://openalex.org/keywords/mitochondrial-disease","display_name":"mitochondrial disease","score":0.7049999833106995},{"id":"https://openalex.org/keywords/disease-susceptibility","display_name":"disease susceptibility","score":0.38499999046325684},{"id":"https://openalex.org/keywords/mitochondrial-lineages","display_name":"mitochondrial lineages","score":0.574999988079071}],"concepts":[{"id":"https://openalex.org/C24586158","wikidata":"https://www.wikidata.org/wiki/Q27075","display_name":"Mitochondrial DNA","level":3,"score":0.9298272132873535},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8501701354980469},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6313869953155518},{"id":"https://openalex.org/C78450430","wikidata":"https://www.wikidata.org/wiki/Q1356230","display_name":"Human mitochondrial DNA haplogroup","level":5,"score":0.4160911738872528},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.3882908821105957},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2797149419784546},{"id":"https://openalex.org/C197754878","wikidata":"https://www.wikidata.org/wiki/Q80711","display_name":"Haplotype","level":4,"score":0.2738523483276367},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.20248323678970337}],"mesh":[{"descriptor_ui":"D004272","descriptor_name":"DNA, Mitochondrial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005075","descriptor_name":"Biological Evolution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005828","descriptor_name":"Genetics, Population","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010375","descriptor_name":"Pedigree","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015418","descriptor_name":"Optic Atrophies, Hereditary","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D017240","descriptor_name":"Mitochondrial Myopathies","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/s0378-1119(99)00295-4","doi":"https://doi.org/10.1016/s0378-1119(99)00295-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0378-1119(99)00295-4","pdf_url":null,"source":{"id":"https://openalex.org/S75702506","display_name":"Gene","issn_l":"0378-1119","issn":["0378-1119","1879-0038"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gene","raw_type":"journal-article"},{"id":"pmid:10570998","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10570998","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gene","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.467.6186","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.467.6186","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.bec.ucla.edu/papers/Wallace_23.5.05_3.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.7246000170707703}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":110,"referenced_works":["https://openalex.org/W45918701","https://openalex.org/W205203631","https://openalex.org/W1271705100","https://openalex.org/W1482076380","https://openalex.org/W1493371020","https://openalex.org/W1497179990","https://openalex.org/W1499722891","https://openalex.org/W1539142107","https://openalex.org/W1557154820","https://openalex.org/W1569332557","https://openalex.org/W1570067108","https://openalex.org/W1576760039","https://openalex.org/W1579208223","https://openalex.org/W1602789634","https://openalex.org/W1682086697","https://openalex.org/W1725242700","https://openalex.org/W1790985176","https://openalex.org/W1794628503","https://openalex.org/W1827563135","https://openalex.org/W1842375801","https://openalex.org/W1895076056","https://openalex.org/W1899095524","https://openalex.org/W1926342884","https://openalex.org/W1965389439","https://openalex.org/W1966087960","https://openalex.org/W1966461639","https://openalex.org/W1967683528","https://openalex.org/W1968952472","https://openalex.org/W1974779272","https://openalex.org/W1975709149","https://openalex.org/W1980681204","https://openalex.org/W1981161568","https://openalex.org/W1982456351","https://openalex.org/W1983857347","https://openalex.org/W1983918667","https://openalex.org/W1986612644","https://openalex.org/W1990210818","https://openalex.org/W1997640580","https://openalex.org/W1998747709","https://openalex.org/W2001348162","https://openalex.org/W2003103396","https://openalex.org/W2003943060","https://openalex.org/W2004878132","https://openalex.org/W2008403014","https://openalex.org/W2013060025","https://openalex.org/W2015797260","https://openalex.org/W2016486719","https://openalex.org/W2017347785","https://openalex.org/W2025773956","https://openalex.org/W2032097381","https://openalex.org/W2036300799","https://openalex.org/W2039977047","https://openalex.org/W2040303536","https://openalex.org/W2040690573","https://openalex.org/W2046226207","https://openalex.org/W2049842051","https://openalex.org/W2052866369","https://openalex.org/W2054556973","https://openalex.org/W2055930407","https://openalex.org/W2056070815","https://openalex.org/W2061574765","https://openalex.org/W2062518633","https://openalex.org/W2064231332","https://openalex.org/W2066058320","https://openalex.org/W2070864958","https://openalex.org/W2072889251","https://openalex.org/W2074866183","https://openalex.org/W2077311097","https://openalex.org/W2079640584","https://openalex.org/W2081216558","https://openalex.org/W2086091822","https://openalex.org/W2089138298","https://openalex.org/W2089958807","https://openalex.org/W2091704552","https://openalex.org/W2092169239","https://openalex.org/W2094177355","https://openalex.org/W2094696217","https://openalex.org/W2095915630","https://openalex.org/W2097706568","https://openalex.org/W2104018711","https://openalex.org/W2105532685","https://openalex.org/W2105795226","https://openalex.org/W2108272863","https://openalex.org/W2109291482","https://openalex.org/W2115585003","https://openalex.org/W2115688047","https://openalex.org/W2119468541","https://openalex.org/W2126877711","https://openalex.org/W2128850814","https://openalex.org/W2129282790","https://openalex.org/W2130295377","https://openalex.org/W2130873319","https://openalex.org/W2144978632","https://openalex.org/W2145700564","https://openalex.org/W2147655348","https://openalex.org/W2149132172","https://openalex.org/W2151034293","https://openalex.org/W2158345466","https://openalex.org/W2159013626","https://openalex.org/W2165290518","https://openalex.org/W2256839430","https://openalex.org/W2760713421","https://openalex.org/W2764687937","https://openalex.org/W2886999415","https://openalex.org/W3035270799","https://openalex.org/W3167852486","https://openalex.org/W4235019056","https://openalex.org/W4242520386","https://openalex.org/W4244299745","https://openalex.org/W4250304621"],"related_works":["https://openalex.org/W7099942441","https://openalex.org/W2118613555","https://openalex.org/W3088850003","https://openalex.org/W862823769","https://openalex.org/W4387959949","https://openalex.org/W1544001506","https://openalex.org/W2129282790","https://openalex.org/W4417067698","https://openalex.org/W2161381504","https://openalex.org/W2168162224"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":12},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":12},{"year":2018,"cited_by_count":14},{"year":2017,"cited_by_count":16},{"year":2016,"cited_by_count":16},{"year":2015,"cited_by_count":15},{"year":2014,"cited_by_count":23},{"year":2013,"cited_by_count":37},{"year":2012,"cited_by_count":14}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2016-06-24T00:00:00"}
