{"id":"https://openalex.org/W2017018262","doi":"https://doi.org/10.1203/00006450-198104001-00956","title":"931 NEWBORNS HAVE DIMINISHED NATURAL KILLER CELL ACTIVITY","display_name":"931 NEWBORNS HAVE DIMINISHED NATURAL KILLER CELL ACTIVITY","publication_year":1981,"publication_date":"1981-04-01","ids":{"openalex":"https://openalex.org/W2017018262","doi":"https://doi.org/10.1203/00006450-198104001-00956","mag":"2017018262"},"language":"en","primary_location":{"id":"doi:10.1203/00006450-198104001-00956","doi":"https://doi.org/10.1203/00006450-198104001-00956","is_oa":false,"landing_page_url":"https://doi.org/10.1203/00006450-198104001-00956","pdf_url":null,"source":{"id":"https://openalex.org/S167664057","display_name":"Pediatric Research","issn_l":"0031-3998","issn":["0031-3998","1530-0447"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111643432","display_name":"Joseph Kaplan","orcid":"https://orcid.org/0009-0001-6589-2033","observed_orcids":["https://orcid.org/0009-0001-6589-2033"]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]},{"id":"https://openalex.org/I4210130818","display_name":"Children's Hospital of Michigan","ror":"https://ror.org/0429x9p85","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800326109","https://openalex.org/I4210130818"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joseph Kaplan","raw_affiliation_strings":["Department of Pediatrics, Wayne State University Medical School, Children's Hospital of Michigan, Detroit"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Wayne State University Medical School, Children's Hospital of Michigan, Detroit","institution_ids":["https://openalex.org/I185443292","https://openalex.org/I4210130818"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083490122","display_name":"Robert O. Bollinger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]},{"id":"https://openalex.org/I4210130818","display_name":"Children's Hospital of Michigan","ror":"https://ror.org/0429x9p85","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800326109","https://openalex.org/I4210130818"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert O Bollinger","raw_affiliation_strings":["Department of Pediatrics, Wayne State University Medical School, Children's Hospital of Michigan, Detroit"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Wayne State University Medical School, Children's Hospital of Michigan, Detroit","institution_ids":["https://openalex.org/I185443292","https://openalex.org/I4210130818"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103546812","display_name":"Thomas C. Shope","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]},{"id":"https://openalex.org/I4210130818","display_name":"Children's Hospital of Michigan","ror":"https://ror.org/0429x9p85","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800326109","https://openalex.org/I4210130818"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas C Shope","raw_affiliation_strings":["Department of Pediatrics, Wayne State University Medical School, Children's Hospital of Michigan, Detroit"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Wayne State University Medical School, Children's Hospital of Michigan, Detroit","institution_ids":["https://openalex.org/I185443292","https://openalex.org/I4210130818"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4390,"currency":"USD","value_usd":4390},"apc_paid":null,"fwci":0.1605,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.44796978,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"15","issue":null,"first_page":"597","last_page":"597"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11510","display_name":"Reproductive System and Pregnancy","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11961","display_name":"Neonatal and Maternal Infections","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/natural-killer-cells","display_name":"natural killer cells","score":0.9929999709129333},{"id":"https://openalex.org/keywords/newborns","display_name":"neonates","score":0.8960000276565552},{"id":"https://openalex.org/keywords/nk-cell-cytotoxicity","display_name":"NK cell cytotoxicity","score":0.8550000190734863},{"id":"https://openalex.org/keywords/k562-cells","display_name":"K562 cells","score":0.8989999890327454},{"id":"https://openalex.org/keywords/effector-to-target-ratio","display_name":"effector-to-target ratio","score":0.8059999942779541},{"id":"https://openalex.org/keywords/nk-cell-inhibition","display_name":"NK cell inhibition","score":0.6209999918937683},{"id":"https://openalex.org/keywords/host-defense","display_name":"host defense","score":0.4779999852180481}],"concepts":[{"id":"https://openalex.org/C182615771","wikidata":"https://www.wikidata.org/wiki/Q1369386","display_name":"Lytic cycle","level":3,"score":0.6260366439819336},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5823931694030762},{"id":"https://openalex.org/C171122931","wikidata":"https://www.wikidata.org/wiki/Q6324626","display_name":"K562 cells","level":3,"score":0.5821751356124878},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.553802490234375},{"id":"https://openalex.org/C2778102761","wikidata":"https://www.wikidata.org/wiki/Q332181","display_name":"Natural killer cell","level":4,"score":0.5474206209182739},{"id":"https://openalex.org/C57409179","wikidata":"https://www.wikidata.org/wiki/Q1218293","display_name":"Lysis","level":2,"score":0.5411455035209656},{"id":"https://openalex.org/C51785407","wikidata":"https://www.wikidata.org/wiki/Q2627568","display_name":"Effector","level":2,"score":0.529167890548706},{"id":"https://openalex.org/C2777761686","wikidata":"https://www.wikidata.org/wiki/Q715347","display_name":"Lymphocyte","level":2,"score":0.47674429416656494},{"id":"https://openalex.org/C73588182","wikidata":"https://www.wikidata.org/wiki/Q2663023","display_name":"Cytolysis","level":4,"score":0.47664815187454224},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.45753294229507446},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.3800075650215149},{"id":"https://openalex.org/C109316439","wikidata":"https://www.wikidata.org/wiki/Q246181","display_name":"Cytotoxicity","level":3,"score":0.2383110523223877},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.12377423048019409},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C2778461978","wikidata":"https://www.wikidata.org/wiki/Q29496","display_name":"Leukemia","level":2,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1203/00006450-198104001-00956","doi":"https://doi.org/10.1203/00006450-198104001-00956","is_oa":false,"landing_page_url":"https://doi.org/10.1203/00006450-198104001-00956","pdf_url":null,"source":{"id":"https://openalex.org/S167664057","display_name":"Pediatric Research","issn_l":"0031-3998","issn":["0031-3998","1530-0447"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric Research","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2009885759","https://openalex.org/W8280425","https://openalex.org/W2007448808","https://openalex.org/W1965898409","https://openalex.org/W1969172043","https://openalex.org/W2077237119","https://openalex.org/W2415685210","https://openalex.org/W1996937350","https://openalex.org/W7100573474","https://openalex.org/W2411768621"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-09-17T22:18:28.273824","created_date":"2016-06-24T00:00:00"}