{"id":"https://openalex.org/W2017009777","doi":"https://doi.org/10.1159/000107778","title":"Laparoscopic versus Open Total Mesorectal Excision: A Comparative Study on Short-Term Outcomes","display_name":"Laparoscopic versus Open Total Mesorectal Excision: A Comparative Study on Short-Term Outcomes","publication_year":2007,"publication_date":"2007-01-01","ids":{"openalex":"https://openalex.org/W2017009777","doi":"https://doi.org/10.1159/000107778","mag":"2017009777","pmid":"https://pubmed.ncbi.nlm.nih.gov/17785982"},"language":"en","primary_location":{"id":"doi:10.1159/000107778","doi":"https://doi.org/10.1159/000107778","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000107778","pdf_url":null,"source":{"id":"https://openalex.org/S178239422","display_name":"Digestive Surgery","issn_l":"0253-4886","issn":["0253-4886","1421-9883","1421-9983"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Digestive Surgery","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112397331","display_name":"A.A.F.A. Veenhof","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I911458345","display_name":"Amsterdam UMC Location Vrije Universiteit Amsterdam","ror":"https://ror.org/00q6h8f30","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833","https://openalex.org/I911458345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"A.A.F.A. Veenhof","raw_affiliation_strings":["Department of Surgery, Vrije Universiteit Medical Center, Amsterdam, The Netherlands","Departments of Surgery,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Vrije Universiteit Medical Center, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I911458345"]},{"raw_affiliation_string":"Departments of Surgery,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102000765","display_name":"Alexander F Engel","orcid":"https://orcid.org/0000-0002-0786-2901","observed_orcids":["https://orcid.org/0000-0002-0786-2901"]},"institutions":[{"id":"https://openalex.org/I4210127060","display_name":"Zaans Medisch Centrum","ror":"https://ror.org/0331x8t04","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210127060"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"A.F. Engel","raw_affiliation_strings":["Department of Surgery, Zaans Medical Center, Zaandam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Zaans Medical Center, Zaandam, The Netherlands","institution_ids":["https://openalex.org/I4210127060"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109161325","display_name":"Mike E. Craanen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M.E. Craanen","raw_affiliation_strings":["Gastroenterology, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterology, and","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112090279","display_name":"Sybren Meijer","orcid":"https://orcid.org/0000-0002-6953-2406","observed_orcids":["https://orcid.org/0000-0002-6953-2406"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S. Meijer","raw_affiliation_strings":["Departments of Surgery,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Surgery,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067689526","display_name":"Elly S.M. de Lange\u2013de Klerk","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I911458345","display_name":"Amsterdam UMC Location Vrije Universiteit Amsterdam","ror":"https://ror.org/00q6h8f30","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833","https://openalex.org/I911458345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"E.S.M. de Lange-de Klerk","raw_affiliation_strings":["Clinical Epidemiology and Biostatistics, Vrije Universiteit Medical Center, Amsterdam,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Epidemiology and Biostatistics, Vrije Universiteit Medical Center, Amsterdam,","institution_ids":["https://openalex.org/I911458345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007361135","display_name":"Donald Leonard van der Peet","orcid":"https://orcid.org/0000-0003-3883-3705","observed_orcids":["https://orcid.org/0000-0003-3883-3705"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D.L. van der Peet","raw_affiliation_strings":["Departments of Surgery,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Surgery,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089490839","display_name":"Wilhelmus J.H.J. Meijerink","orcid":"https://orcid.org/0000-0002-5402-0811","observed_orcids":["https://orcid.org/0000-0002-5402-0811"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W.J.H.J. Meijerink","raw_affiliation_strings":["Departments of Surgery,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Surgery,","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5057145168","display_name":"Miguel A. Cuesta","orcid":"https://orcid.org/0000-0002-3109-6995","observed_orcids":["https://orcid.org/0000-0002-3109-6995"]},"institutions":[{"id":"https://openalex.org/I911458345","display_name":"Amsterdam UMC Location Vrije Universiteit Amsterdam","ror":"https://ror.org/00q6h8f30","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833","https://openalex.org/I911458345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"M.A. Cuesta","raw_affiliation_strings":["Department of Surgery , Vrije Universiteit Medical Center Post bus 7057 NL-1007 MB Amsterdam ( The Netherlands","Departments of Surgery,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery , Vrije Universiteit Medical Center Post bus 7057 NL-1007 MB Amsterdam ( The Netherlands","institution_ids":["https://openalex.org/I911458345"]},{"raw_affiliation_string":"Departments of Surgery,","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.6087,"has_fulltext":true,"cited_by_count":33,"citation_normalized_percentile":{"value":0.83145346,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"24","issue":"5","first_page":"367","last_page":"374"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10335","display_name":"Colorectal Cancer Surgical Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10335","display_name":"Colorectal Cancer Surgical Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10696","display_name":"Gastric Cancer Management and Outcomes","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12020","display_name":"Enhanced Recovery After Surgery","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/laparoscopic-total-mesorectal-excision","display_name":"laparoscopic total mesorectal excision","score":0.9470000267028809},{"id":"https://openalex.org/keywords/rectal-cancer","display_name":"rectal cancer","score":0.996999979019165},{"id":"https://openalex.org/keywords/abdominoperineal-resection","display_name":"abdominoperineal resection","score":0.9739999771118164},{"id":"https://openalex.org/keywords/early-postoperative-outcomes","display_name":"early postoperative outcomes","score":0.7950000166893005},{"id":"https://openalex.org/keywords/postoperative-complications","display_name":"postoperative complications","score":0.8790000081062317},{"id":"https://openalex.org/keywords/blood-loss","display_name":"blood loss","score":0.7850000262260437},{"id":"https://openalex.org/keywords/length-of-hospital-stay","display_name":"length of hospital stay","score":0.8040000200271606},{"id":"https://openalex.org/keywords/disease-free-survival","display_name":"disease-free survival","score":0.7940000295639038},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.9879999756813049}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9831777811050415},{"id":"https://openalex.org/C2777201421","wikidata":"https://www.wikidata.org/wiki/Q2445481","display_name":"Total mesorectal excision","level":4,"score":0.8545597195625305},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.6884222030639648},{"id":"https://openalex.org/C2780047204","wikidata":"https://www.wikidata.org/wiki/Q675754","display_name":"Laparoscopy","level":2,"score":0.6811961531639099},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.6386514902114868},{"id":"https://openalex.org/C2781171867","wikidata":"https://www.wikidata.org/wiki/Q3933360","display_name":"Abdominoperineal resection","level":4,"score":0.5248432159423828},{"id":"https://openalex.org/C2776111594","wikidata":"https://www.wikidata.org/wiki/Q675754","display_name":"Laparoscopic surgery","level":3,"score":0.4990835189819336},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.326480507850647},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.21331092715263367}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000714","descriptor_name":"Anastomosis, Surgical","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D003082","descriptor_name":"Colectomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009426","descriptor_name":"Netherlands","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D010535","descriptor_name":"Laparoscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012004","descriptor_name":"Rectal Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D012004","descriptor_name":"Rectal Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D012004","descriptor_name":"Rectal Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015996","descriptor_name":"Survival Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016063","descriptor_name":"Blood Loss, Surgical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018572","descriptor_name":"Disease-Free Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018709","descriptor_name":"Statistics, Nonparametric","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1159/000107778","doi":"https://doi.org/10.1159/000107778","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000107778","pdf_url":null,"source":{"id":"https://openalex.org/S178239422","display_name":"Digestive Surgery","issn_l":"0253-4886","issn":["0253-4886","1421-9883","1421-9983"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Digestive Surgery","raw_type":"journal-article"},{"id":"pmid:17785982","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17785982","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Digestive surgery","raw_type":"Clinical Trial"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W120866572","https://openalex.org/W1218787212","https://openalex.org/W1516923186","https://openalex.org/W1981116409","https://openalex.org/W1982493512","https://openalex.org/W1985762326","https://openalex.org/W1989657003","https://openalex.org/W2005745526","https://openalex.org/W2007114188","https://openalex.org/W2009781085","https://openalex.org/W2016957211","https://openalex.org/W2023586228","https://openalex.org/W2035182914","https://openalex.org/W2055489398","https://openalex.org/W2062944317","https://openalex.org/W2068985574","https://openalex.org/W2071396427","https://openalex.org/W2087507912","https://openalex.org/W2127119144","https://openalex.org/W2132565869","https://openalex.org/W2136453296","https://openalex.org/W2138898868","https://openalex.org/W2169731203","https://openalex.org/W2185791496","https://openalex.org/W2730169823","https://openalex.org/W4246949592"],"related_works":["https://openalex.org/W2315916840","https://openalex.org/W2355762483","https://openalex.org/W2394033319","https://openalex.org/W2350710146","https://openalex.org/W2340069550","https://openalex.org/W2366631703","https://openalex.org/W2361277158","https://openalex.org/W2365734438","https://openalex.org/W2101673328","https://openalex.org/W2104160119"],"abstract_inverted_index":{"BACKGROUND:":[0],"Laparoscopic":[1,71],"total":[2],"mesorectal":[3],"excision":[4],"(TME)":[5],"is":[6,192],"being":[7],"used":[8],"in":[9,24,122,177],"rectal":[10,48,65,190],"cancer":[11,49,191],"more":[12],"frequently.":[13],"The":[14,104],"aim":[15],"of":[16,41,55,106],"this":[17,34],"study":[18,184],"was":[19,85,135,154],"to":[20,75],"analyze":[21],"the":[22,38,123,158,165,171],"differences":[23],"short-term":[25,39,200],"outcomes":[26,40],"between":[27,113,170],"open":[28,60,166,203],"and":[29,108,161,179,195],"laparoscopic":[30,62,124,142,159,187],"TME.":[31,204],"METHODS:":[32],"In":[33],"nonrandomized":[35],"consecutive":[36],"study,":[37],"100":[42],"patients":[43,57,118,138],"undergoing":[44],"TME":[45,63,188],"for":[46,64,137,157,164,189],"proven":[47],"were":[50,69,111],"analyzed.":[51],"RESULTS:":[52],"Two":[53],"groups":[54,68,172],"50":[56],"underwent":[58,140],"an":[59],"or":[61],"cancer.":[66],"Both":[67],"comparable.":[70],"surgery":[72],"took":[73],"longer":[74],"perform":[76],"(250":[77],"vs.":[78,92,127,146],"197.5":[79],"min,":[80],"p":[81,95,130,149],"<":[82,96],"0.01),":[83],"but":[84],"accompanied":[86],"by":[87],"less":[88],"blood":[89],"loss":[90],"(350":[91],"800":[93],"ml,":[94],"0.01).":[97],"Enteric":[98],"function":[99],"recovered":[100],"sooner":[101],"after":[102],"laparoscopy.":[103],"numbers":[105],"major":[107,120],"minor":[109],"complications":[110,121],"comparable":[112],"both":[114],"groups,":[115],"although":[116],"fewer":[117],"had":[119],"group":[125,160],"(6":[126],"15":[128],"patients,":[129],"=":[131,150],"0.03).":[132],"Hospital":[133],"stay":[134],"shorter":[136],"who":[139],"a":[141,193],"abdominoperineal":[143],"resection":[144],"(10":[145],"12":[147],"days,":[148],"0.04).":[151],"Median":[152],"follow-up":[153],"17":[155],"months":[156,163],"22":[162],"group.":[167],"Survival":[168],"analyses":[169],"showed":[173],"no":[174],"statistical":[175],"difference":[176],"disease-free":[178],"overall":[180],"survival.":[181],"CONCLUSION:":[182],"This":[183],"shows":[185],"that":[186],"safe":[194],"feasible":[196],"technique":[197],"with":[198],"some":[199],"benefits":[201],"over":[202]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}