{"id":"https://openalex.org/W2016882845","doi":"https://doi.org/10.1097/tp.0b013e318242be28","title":"Effect of Everolimus on Left Ventricular Hypertrophy of De Novo Kidney Transplant Recipients","display_name":"Effect of Everolimus on Left Ventricular Hypertrophy of De Novo Kidney Transplant Recipients","publication_year":2012,"publication_date":"2012-02-08","ids":{"openalex":"https://openalex.org/W2016882845","doi":"https://doi.org/10.1097/tp.0b013e318242be28","mag":"2016882845","pmid":"https://pubmed.ncbi.nlm.nih.gov/22318246"},"language":"en","primary_location":{"id":"doi:10.1097/tp.0b013e318242be28","doi":"https://doi.org/10.1097/tp.0b013e318242be28","is_oa":false,"landing_page_url":"https://doi.org/10.1097/tp.0b013e318242be28","pdf_url":null,"source":{"id":"https://openalex.org/S11564597","display_name":"Transplantation","issn_l":"0041-1337","issn":["0041-1337","1534-6080"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transplantation","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079361114","display_name":"Ernesto Paoletti","orcid":"https://orcid.org/0000-0002-5509-6252","observed_orcids":["https://orcid.org/0000-0002-5509-6252"]},"institutions":[{"id":"https://openalex.org/I4210146472","display_name":"Ospedale Policlinico San Martino","ror":"https://ror.org/04d7es448","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210146472","https://openalex.org/I4210153126","https://openalex.org/I4405264730"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Ernesto Paoletti","raw_affiliation_strings":["Division of Nephrology, Dialysis and Transplantation, IRCCS Azienda Ospedaliera Universitaria San Martino-IST Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy. ernesto.paoletti@hsanmartino.it","August 2011. Revision requested 25 August 2011","Division of Nephrology, Dialysis and Transplantation, IRCCS Azienda Ospedaliera Universitaria San Martino-IST Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy","Dr. Ernesto Paoletti, Divisione di Nefrologia, Dialisi, e Trapianto, IRCCS Azienda Ospedaliera Universitaria San Martino-IST Istituto Nazionale per la Ricerca sul Cancro, L.go R.Benzi 10, 16132, Genova, Italy. E-mail: [email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology, Dialysis and Transplantation, IRCCS Azienda Ospedaliera Universitaria San Martino-IST Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy. ernesto.paoletti@hsanmartino.it","institution_ids":["https://openalex.org/I4210146472"]},{"raw_affiliation_string":"August 2011. Revision requested 25 August 2011","institution_ids":[]},{"raw_affiliation_string":"Division of Nephrology, Dialysis and Transplantation, IRCCS Azienda Ospedaliera Universitaria San Martino-IST Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy","institution_ids":["https://openalex.org/I4210146472"]},{"raw_affiliation_string":"Dr. Ernesto Paoletti, Divisione di Nefrologia, Dialisi, e Trapianto, IRCCS Azienda Ospedaliera Universitaria San Martino-IST Istituto Nazionale per la Ricerca sul Cancro, L.go R.Benzi 10, 16132, Genova, Italy. E-mail: [email\u00a0protected]","institution_ids":["https://openalex.org/I4210146472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025733060","display_name":"Luigina Marsano","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210146472","display_name":"Ospedale Policlinico San Martino","ror":"https://ror.org/04d7es448","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210146472","https://openalex.org/I4210153126","https://openalex.org/I4405264730"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Luigina Marsano","raw_affiliation_strings":["Division of Nephrology, Dialysis and Transplantation, IRCCS Azienda Ospedaliera Universitaria San Martino-IST Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology, Dialysis and Transplantation, IRCCS Azienda Ospedaliera Universitaria San Martino-IST Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy","institution_ids":["https://openalex.org/I4210146472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113510769","display_name":"Diego Bellino","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210146472","display_name":"Ospedale Policlinico San Martino","ror":"https://ror.org/04d7es448","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210146472","https://openalex.org/I4210153126","https://openalex.org/I4405264730"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Diego Bellino","raw_affiliation_strings":["Division of Nephrology, Dialysis and Transplantation, IRCCS Azienda Ospedaliera Universitaria San Martino-IST Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology, Dialysis and Transplantation, IRCCS Azienda Ospedaliera Universitaria San Martino-IST Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy","institution_ids":["https://openalex.org/I4210146472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076201267","display_name":"Paolo Cassottana","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210146472","display_name":"Ospedale Policlinico San Martino","ror":"https://ror.org/04d7es448","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210146472","https://openalex.org/I4210153126","https://openalex.org/I4405264730"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Paolo Cassottana","raw_affiliation_strings":["Division of Cardiology, IRCCS Azienda Ospedaliera Universitaria San Martino-IST Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, IRCCS Azienda Ospedaliera Universitaria San Martino-IST Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy","institution_ids":["https://openalex.org/I4210146472"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045507293","display_name":"Giuseppe Cannella","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210146472","display_name":"Ospedale Policlinico San Martino","ror":"https://ror.org/04d7es448","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210146472","https://openalex.org/I4210153126","https://openalex.org/I4405264730"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giuseppe Cannella","raw_affiliation_strings":["Division of Nephrology, Dialysis and Transplantation, IRCCS Azienda Ospedaliera Universitaria San Martino-IST Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology, Dialysis and Transplantation, IRCCS Azienda Ospedaliera Universitaria San Martino-IST Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy","institution_ids":["https://openalex.org/I4210146472"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5079361114"],"corresponding_institution_ids":["https://openalex.org/I4210146472"],"apc_list":null,"apc_paid":null,"fwci":3.7709,"has_fulltext":false,"cited_by_count":53,"citation_normalized_percentile":{"value":0.94235204,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":99},"biblio":{"volume":"93","issue":"5","first_page":"503","last_page":"508"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/everolimus","display_name":"everolimus","score":1.0},{"id":"https://openalex.org/keywords/left-ventricular-hypertrophy","display_name":"left ventricular hypertrophy","score":0.9869999885559082},{"id":"https://openalex.org/keywords/kidney-transplantation","display_name":"kidney transplantation","score":0.847000002861023},{"id":"https://openalex.org/keywords/cyclosporine","display_name":"cyclosporine","score":0.8040000200271606},{"id":"https://openalex.org/keywords/mtor-inhibitors","display_name":"mTOR inhibitors","score":0.7979999780654907},{"id":"https://openalex.org/keywords/calcineurin-inhibitors","display_name":"calcineurin inhibitors","score":0.7770000100135803},{"id":"https://openalex.org/keywords/left-ventricular-mass-index","display_name":"left ventricular mass index","score":0.9089999794960022},{"id":"https://openalex.org/keywords/immunosuppression","display_name":"immunosuppression","score":0.6570000052452087},{"id":"https://openalex.org/keywords/blood-pressure","display_name":"blood pressure","score":0.6669999957084656},{"id":"https://openalex.org/keywords/left-ventricular-wall-thickness","display_name":"left ventricular wall thickness","score":0.8199999928474426},{"id":"https://openalex.org/keywords/proteinuria","display_name":"proteinuria","score":0.6169999837875366}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8303506374359131},{"id":"https://openalex.org/C2776002628","wikidata":"https://www.wikidata.org/wiki/Q1628627","display_name":"Left ventricular hypertrophy","level":3,"score":0.8094122409820557},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6495132446289062},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6290807723999023},{"id":"https://openalex.org/C2779699572","wikidata":"https://www.wikidata.org/wiki/Q421052","display_name":"Everolimus","level":2,"score":0.5660033226013184},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.5267944931983948},{"id":"https://openalex.org/C128057223","wikidata":"https://www.wikidata.org/wiki/Q420566","display_name":"Calcineurin","level":3,"score":0.4550614356994629},{"id":"https://openalex.org/C2780306776","wikidata":"https://www.wikidata.org/wiki/Q426660","display_name":"Creatinine","level":2,"score":0.4326150715351105},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.4281827211380005},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.39754366874694824}],"mesh":[{"descriptor_ui":"D000068338","descriptor_name":"Everolimus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004359","descriptor_name":"Drug Therapy, Combination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007166","descriptor_name":"Immunosuppressive Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D007166","descriptor_name":"Immunosuppressive Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D007558","descriptor_name":"Italy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014463","descriptor_name":"Ultrasonography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016009","descriptor_name":"Chi-Square Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016014","descriptor_name":"Linear Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016030","descriptor_name":"Kidney Transplantation","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D016572","descriptor_name":"Cyclosporine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017379","descriptor_name":"Hypertrophy, Left Ventricular","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D017379","descriptor_name":"Hypertrophy, Left Ventricular","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D017379","descriptor_name":"Hypertrophy, Left Ventricular","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D017379","descriptor_name":"Hypertrophy, Left Ventricular","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D017379","descriptor_name":"Hypertrophy, Left Ventricular","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D018570","descriptor_name":"Risk Assessment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020123","descriptor_name":"Sirolimus","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D020123","descriptor_name":"Sirolimus","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1097/tp.0b013e318242be28","doi":"https://doi.org/10.1097/tp.0b013e318242be28","is_oa":false,"landing_page_url":"https://doi.org/10.1097/tp.0b013e318242be28","pdf_url":null,"source":{"id":"https://openalex.org/S11564597","display_name":"Transplantation","issn_l":"0041-1337","issn":["0041-1337","1534-6080"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transplantation","raw_type":"journal-article"},{"id":"pmid:22318246","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22318246","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transplantation","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W1600996638","https://openalex.org/W1963859566","https://openalex.org/W1987532648","https://openalex.org/W1989398460","https://openalex.org/W1993316627","https://openalex.org/W1996167459","https://openalex.org/W1999734772","https://openalex.org/W2006968362","https://openalex.org/W2011253818","https://openalex.org/W2028549543","https://openalex.org/W2042293234","https://openalex.org/W2052371215","https://openalex.org/W2066937445","https://openalex.org/W2072795041","https://openalex.org/W2077685590","https://openalex.org/W2083313568","https://openalex.org/W2087351164","https://openalex.org/W2094402868","https://openalex.org/W2096073058","https://openalex.org/W2096565242","https://openalex.org/W2107218339","https://openalex.org/W2115504370","https://openalex.org/W2125091672","https://openalex.org/W2132072950","https://openalex.org/W2137834821","https://openalex.org/W2142288396","https://openalex.org/W2151970753","https://openalex.org/W2159783335"],"related_works":["https://openalex.org/W2523224882","https://openalex.org/W2024785109","https://openalex.org/W1963859566","https://openalex.org/W2336022586","https://openalex.org/W2533264821","https://openalex.org/W2297453249","https://openalex.org/W1985669063","https://openalex.org/W1528636297","https://openalex.org/W2084726553","https://openalex.org/W1996167459"],"abstract_inverted_index":{"BACKGROUND:":[0],"Although":[1],"conversion":[2],"from":[3],"calcineurin":[4],"inhibitors":[5,11],"to":[6,13,79,88,135,142,193,223,248],"mammalian":[7],"target":[8],"of":[9,36,58,67,113,219,230,241,257],"rapamycin":[10],"proved":[12,247],"be":[14,249],"effective":[15,250],"in":[16,22,148,152,179,196,251,254],"regressing":[17,252],"left":[18,62,203,262],"ventricular":[19,63,204,263],"hypertrophy":[20],"(LVH)":[21],"renal":[23],"transplant":[24],"recipients":[25],"(RTRs)":[26],"with":[27,211],"chronic":[28],"allograft":[29],"dysfunction,":[30],"there":[31],"are":[32],"currently":[33],"no":[34],"reports":[35],"randomized":[37],"trials":[38],"on":[39,60],"this":[40],"issue":[41],"involving":[42],"de":[43],"novo":[44],"RTRs":[45,70,255],"administered":[46,134],"everolimus":[47],"(EVL).":[48],"METHODS:":[49],"This":[50],"randomized,":[51],"open-label,":[52],"controlled":[53],"trial":[54],"evaluated":[55,121],"the":[56,61,153,180,198,202,215,231],"effect":[57],"EVL":[59,80,181,208,242],"mass":[64],"index":[65],"(LVMi)":[66],"30":[68],"nondiabetic":[69],"(21":[71],"men;":[72],"age":[73],"28-65":[74],"years).":[75],"Ten":[76],"were":[77,119,150,214],"allocated":[78],"plus":[81,243],"reduced-exposure":[82],"cyclosporine":[83],"A":[84],"(CsA),":[85],"and":[86,100,116,167,201],"20":[87],"standard":[89],"dose":[90],"CsA.":[91],"LVMi":[92,176,213,233],"was":[93,133],"assessed":[94],"by":[95,260],"echocardiography":[96],"both":[97,197],"at":[98],"baseline":[99,212],"1":[101],"year":[102],"later.":[103],"Blood":[104],"pressure":[105],"(BP),":[106],"hemoglobin,":[107],"serum":[108],"creatinine,":[109],"lipids,":[110],"trough":[111],"levels":[112],"immunosuppressive":[114,238],"drugs,":[115],"daily":[117],"proteinuria":[118],"also":[120],"twice":[122],"monthly.":[123],"Antihypertensive":[124],"therapy":[125,209],"that":[126,227],"did":[127],"not":[128],"include":[129],"renin-angiotensin":[130],"system":[131],"blockers":[132],"achieve":[136],"BP":[137,149],"less":[138],"than":[139],"or":[140],"equal":[141],"130/80":[143],"mm":[144,162],"Hg.":[145],"RESULTS:":[146],"Changes":[147],"similar":[151],"two":[154],"groups":[155],"(between":[156,184],"group":[157,182,185],"difference":[158,186],"1.2":[159],"\u00b1":[160,169,188],"5.7":[161],"Hg,":[163],"P=0.84":[164],"for":[165,172],"systolic,":[166],"-1.5":[168],"3.7,":[170],"P=0.69,":[171],"diastolic":[173],"BP),":[174],"whereas":[175],"significantly":[177],"decreased":[178],"alone":[183],"9.2":[187],"3.1":[189],"g/m(2.7),":[190],"P=0.005),":[191],"due":[192],"a":[194,224],"reduction":[195],"interventricular":[199],"septum":[200],"posterior":[205],"wall":[206,264],"thickness.":[207,265],"together":[210],"only":[216],"significant":[217],"predictors":[218],"LVH":[220,253],"regression":[221],"according":[222],"multivariate":[225],"model":[226],"explained":[228],"49%":[229],"total":[232],"variance":[234],"(P=0.0015).":[235],"CONCLUSIONS:":[236],"An":[237],"regimen":[239],"consisting":[240],"reduced":[244],"exposure":[245],"CsA":[246],"regardless":[256],"BP,":[258],"mainly":[259],"reducing":[261]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":9},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}