{"id":"https://openalex.org/W2016863609","doi":"https://doi.org/10.1038/sj.bjc.6601373","title":"Differential expression profiling of head and neck squamous cell carcinoma (HNSCC)","display_name":"Differential expression profiling of head and neck squamous cell carcinoma (HNSCC)","publication_year":2003,"publication_date":"2003-11-01","ids":{"openalex":"https://openalex.org/W2016863609","doi":"https://doi.org/10.1038/sj.bjc.6601373","mag":"2016863609","pmid":"https://pubmed.ncbi.nlm.nih.gov/14612907","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2394447"},"language":"en","primary_location":{"id":"doi:10.1038/sj.bjc.6601373","doi":"https://doi.org/10.1038/sj.bjc.6601373","is_oa":true,"landing_page_url":"https://doi.org/10.1038/sj.bjc.6601373","pdf_url":"https://www.nature.com/articles/6601373.pdf","source":{"id":"https://openalex.org/S62966998","display_name":"British Journal of Cancer","issn_l":"0007-0920","issn":["0007-0920","1532-1827"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Cancer","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.nature.com/articles/6601373.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113843591","display_name":"Fran\u00e7oise Lemaire","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"F Lemaire","raw_affiliation_strings":["Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, 1 Rue Laurent Fries, BP 10142, 67404 Illkirch cedex, France","Institut de Ge\u0301ne\u0301tique et de Biologie Mole\u0301culaire et Cellulaire, CNRS/INSERM/ULP, 1 rue Laurent Fries, BP 10142, 67404 Illkirch cedex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, 1 Rue Laurent Fries, BP 10142, 67404 Illkirch cedex, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872"]},{"raw_affiliation_string":"Institut de Ge\u0301ne\u0301tique et de Biologie Mole\u0301culaire et Cellulaire, CNRS/INSERM/ULP, 1 rue Laurent Fries, BP 10142, 67404 Illkirch cedex, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010962890","display_name":"R Millon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405277693","display_name":"Institut Strauss","ror":"https://ror.org/03k1y0r37","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4405277693"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"R Millon","raw_affiliation_strings":["UPRES EA 34-30, Centre Paul Strauss, 3 rue de la Porte de l'H\u00f4pital, 67085, Strasbourg, France","UPRES EA 34-30, Centre Paul Strauss, 3 rue de la Porte de l'H\u00f4pital, Strasbourg, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UPRES EA 34-30, Centre Paul Strauss, 3 rue de la Porte de l'H\u00f4pital, 67085, Strasbourg, France","institution_ids":["https://openalex.org/I4405277693"]},{"raw_affiliation_string":"UPRES EA 34-30, Centre Paul Strauss, 3 rue de la Porte de l'H\u00f4pital, Strasbourg, France","institution_ids":["https://openalex.org/I4405277693"]}]},{"author_position":"middle","author":{"id":null,"display_name":"J Young","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"J Young","raw_affiliation_strings":["Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, 1 Rue Laurent Fries, BP 10142, Illkirch cedex, 67404, France","Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, Illkirch cedex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, 1 Rue Laurent Fries, BP 10142, Illkirch cedex, 67404, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872"]},{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, Illkirch cedex, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044582568","display_name":"Anne Cromer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"A Cromer","raw_affiliation_strings":["Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, 1 Rue Laurent Fries, BP 10142, Illkirch cedex, 67404, France","Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, Illkirch cedex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, 1 Rue Laurent Fries, BP 10142, Illkirch cedex, 67404, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872"]},{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, Illkirch cedex, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111485410","display_name":"Christine Wasylyk","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"C Wasylyk","raw_affiliation_strings":["Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, 1 Rue Laurent Fries, BP 10142, Illkirch cedex, 67404, France","Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, Illkirch cedex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, 1 Rue Laurent Fries, BP 10142, Illkirch cedex, 67404, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872"]},{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, Illkirch cedex, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872"]}]},{"author_position":"middle","author":{"id":null,"display_name":"I Schultz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405277693","display_name":"Institut Strauss","ror":"https://ror.org/03k1y0r37","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4405277693"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"I Schultz","raw_affiliation_strings":["UPRES EA 34-30, Centre Paul Strauss, 3 rue de la Porte de l'H\u00f4pital, 67085, Strasbourg, France","UPRES EA 34-30, Centre Paul Strauss, 3 rue de la Porte de l'H\u00f4pital, Strasbourg, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UPRES EA 34-30, Centre Paul Strauss, 3 rue de la Porte de l'H\u00f4pital, 67085, Strasbourg, France","institution_ids":["https://openalex.org/I4405277693"]},{"raw_affiliation_string":"UPRES EA 34-30, Centre Paul Strauss, 3 rue de la Porte de l'H\u00f4pital, Strasbourg, France","institution_ids":["https://openalex.org/I4405277693"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111925943","display_name":"D M\u00fcller","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405277693","display_name":"Institut Strauss","ror":"https://ror.org/03k1y0r37","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4405277693"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"D Muller","raw_affiliation_strings":["UPRES EA 34-30, Centre Paul Strauss, 3 rue de la Porte de l'H\u00f4pital, 67085, Strasbourg, France","UPRES EA 34-30, Centre Paul Strauss, 3 rue de la Porte de l'H\u00f4pital, Strasbourg, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UPRES EA 34-30, Centre Paul Strauss, 3 rue de la Porte de l'H\u00f4pital, 67085, Strasbourg, France","institution_ids":["https://openalex.org/I4405277693"]},{"raw_affiliation_string":"UPRES EA 34-30, Centre Paul Strauss, 3 rue de la Porte de l'H\u00f4pital, Strasbourg, France","institution_ids":["https://openalex.org/I4405277693"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003904292","display_name":"Patricia Marchal","orcid":"https://orcid.org/0000-0001-6505-4956","observed_orcids":["https://orcid.org/0000-0001-6505-4956"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"P Marchal","raw_affiliation_strings":["Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, 1 Rue Laurent Fries, BP 10142, Illkirch cedex, 67404, France","Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, Illkirch cedex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, 1 Rue Laurent Fries, BP 10142, Illkirch cedex, 67404, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872"]},{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, Illkirch cedex, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872"]}]},{"author_position":"middle","author":{"id":null,"display_name":"C Zhao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"C Zhao","raw_affiliation_strings":["Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, 1 Rue Laurent Fries, BP 10142, Illkirch cedex, 67404, France","Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, Illkirch cedex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, 1 Rue Laurent Fries, BP 10142, Illkirch cedex, 67404, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872"]},{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, Illkirch cedex, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039053824","display_name":"D Melle","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D Melle","raw_affiliation_strings":["Exonhit Therapeutics, 65 Boulevard Mass\u00e9na, Paris, F-75013, France","Exonhit Therapeutics, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Exonhit Therapeutics, 65 Boulevard Mass\u00e9na, Paris, F-75013, France","institution_ids":[]},{"raw_affiliation_string":"Exonhit Therapeutics, Paris, France","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019958940","display_name":"Laurent P. Bracco","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"L Bracco","raw_affiliation_strings":["Exonhit Therapeutics, 65 Boulevard Mass\u00e9na, Paris, F-75013, France","Institut de genetique et de biologie moleculaire et cellulai"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Exonhit Therapeutics, 65 Boulevard Mass\u00e9na, Paris, F-75013, France","institution_ids":[]},{"raw_affiliation_string":"Institut de genetique et de biologie moleculaire et cellulai","institution_ids":["https://openalex.org/I4210086872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012812582","display_name":"Joseph Abecassis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405277693","display_name":"Institut Strauss","ror":"https://ror.org/03k1y0r37","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4405277693"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"J Abecassis","raw_affiliation_strings":["UPRES EA 34-30, Centre Paul Strauss, 3 rue de la Porte de l'H\u00f4pital, 67085, Strasbourg, France","UPRES EA 34-30, Centre Paul Strauss, 3 rue de la Porte de l'H\u00f4pital, Strasbourg, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UPRES EA 34-30, Centre Paul Strauss, 3 rue de la Porte de l'H\u00f4pital, 67085, Strasbourg, France","institution_ids":["https://openalex.org/I4405277693"]},{"raw_affiliation_string":"UPRES EA 34-30, Centre Paul Strauss, 3 rue de la Porte de l'H\u00f4pital, Strasbourg, France","institution_ids":["https://openalex.org/I4405277693"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046195663","display_name":"Bohdan Wasylyk","orcid":"https://orcid.org/0000-0002-1718-1237","observed_orcids":["https://orcid.org/0000-0002-1718-1237"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"B Wasylyk","raw_affiliation_strings":["Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, 1 Rue Laurent Fries, BP 10142, Illkirch cedex, 67404, France","Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, Illkirch cedex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, 1 Rue Laurent Fries, BP 10142, Illkirch cedex, 67404, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872"]},{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, Illkirch cedex, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5046195663"],"corresponding_institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872"],"apc_list":{"value":5190,"currency":"USD","value_usd":5190},"apc_paid":{"value":5190,"currency":"USD","value_usd":5190},"fwci":8.342,"has_fulltext":true,"cited_by_count":75,"citation_normalized_percentile":{"value":0.9792352,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"89","issue":"10","first_page":"1940","last_page":"1949"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/head-and-neck-squamous-cell-carcinoma","display_name":"head and neck squamous cell carcinoma","score":1.0},{"id":"https://openalex.org/keywords/hypopharyngeal-cancer","display_name":"hypopharyngeal cancer","score":0.8960000276565552},{"id":"https://openalex.org/keywords/differential-gene-expression","display_name":"differential gene expression","score":0.9259999990463257},{"id":"https://openalex.org/keywords/differentially-expressed-genes","display_name":"differentially expressed genes","score":0.8650000095367432},{"id":"https://openalex.org/keywords/keratinocyte-differentiation","display_name":"keratinocyte differentiation","score":0.7799999713897705},{"id":"https://openalex.org/keywords/angiogenesis","display_name":"angiogenesis","score":0.9980000257492065},{"id":"https://openalex.org/keywords/detoxification","display_name":"detoxification","score":0.527999997138977},{"id":"https://openalex.org/keywords/cell-surface-receptors","display_name":"cell surface receptors","score":0.9649999737739563},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.7609999775886536},{"id":"https://openalex.org/keywords/therapeutic-target","display_name":"therapeutic target","score":0.996999979019165}],"concepts":[{"id":"https://openalex.org/C2776833033","wikidata":"https://www.wikidata.org/wiki/Q1783924","display_name":"Head and neck squamous-cell carcinoma","level":4,"score":0.7403679490089417},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6636025309562683},{"id":"https://openalex.org/C18431079","wikidata":"https://www.wikidata.org/wiki/Q1502169","display_name":"Gene expression profiling","level":4,"score":0.6294694542884827},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5220046639442444},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.478645920753479},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.43083032965660095},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.4136436879634857},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3522157073020935},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3278637230396271},{"id":"https://openalex.org/C2776530083","wikidata":"https://www.wikidata.org/wiki/Q1783924","display_name":"Head and neck cancer","level":3,"score":0.3046360909938812},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.21988797187805176},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1838819682598114}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006258","descriptor_name":"Head and Neck Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D006258","descriptor_name":"Head and Neck Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009389","descriptor_name":"Neovascularization, Pathologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015152","descriptor_name":"Blotting, Northern","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015603","descriptor_name":"Keratinocytes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017931","descriptor_name":"DNA Primers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018076","descriptor_name":"DNA, Complementary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1038/sj.bjc.6601373","doi":"https://doi.org/10.1038/sj.bjc.6601373","is_oa":true,"landing_page_url":"https://doi.org/10.1038/sj.bjc.6601373","pdf_url":"https://www.nature.com/articles/6601373.pdf","source":{"id":"https://openalex.org/S62966998","display_name":"British Journal of Cancer","issn_l":"0007-0920","issn":["0007-0920","1532-1827"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Cancer","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2394447","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2394447","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Br J Cancer","raw_type":"Text"},{"id":"pmid:14612907","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14612907","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British journal of cancer","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-04143693v1","doi":null,"is_oa":true,"landing_page_url":"https://hal.science/hal-04143693v1/document","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"British Journal of Cancer, 2003, 89 (10), pp.1940-1949. ⟨10.1038/sj.bjc.6601373⟩","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1038/sj.bjc.6601373","doi":"https://doi.org/10.1038/sj.bjc.6601373","is_oa":true,"landing_page_url":"https://doi.org/10.1038/sj.bjc.6601373","pdf_url":"https://www.nature.com/articles/6601373.pdf","source":{"id":"https://openalex.org/S62966998","display_name":"British Journal of Cancer","issn_l":"0007-0920","issn":["0007-0920","1532-1827"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Cancer","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320309749","display_name":"Association pour la Recherche sur le Cancer","ror":"https://ror.org/0489qz649"},{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320322892","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2016863609.pdf","grobid_xml":"https://content.openalex.org/works/W2016863609.grobid-xml"},"referenced_works_count":78,"referenced_works":["https://openalex.org/W24809142","https://openalex.org/W94505367","https://openalex.org/W127054058","https://openalex.org/W170257915","https://openalex.org/W1503072895","https://openalex.org/W1510759553","https://openalex.org/W1819302943","https://openalex.org/W1886431664","https://openalex.org/W1964017918","https://openalex.org/W1965644421","https://openalex.org/W1968324652","https://openalex.org/W1969432263","https://openalex.org/W1973134510","https://openalex.org/W1974582859","https://openalex.org/W1981814823","https://openalex.org/W1983287748","https://openalex.org/W1988539946","https://openalex.org/W1989566285","https://openalex.org/W1995342232","https://openalex.org/W2001679040","https://openalex.org/W2001703565","https://openalex.org/W2003170398","https://openalex.org/W2003344363","https://openalex.org/W2003678731","https://openalex.org/W2004792969","https://openalex.org/W2010780067","https://openalex.org/W2015631023","https://openalex.org/W2019068481","https://openalex.org/W2023542382","https://openalex.org/W2023735985","https://openalex.org/W2024863517","https://openalex.org/W2027394986","https://openalex.org/W2029253199","https://openalex.org/W2029988520","https://openalex.org/W2030430017","https://openalex.org/W2034936705","https://openalex.org/W2036699952","https://openalex.org/W2039616467","https://openalex.org/W2040872871","https://openalex.org/W2043308960","https://openalex.org/W2048091379","https://openalex.org/W2049948758","https://openalex.org/W2056229530","https://openalex.org/W2059201167","https://openalex.org/W2059662683","https://openalex.org/W2061080345","https://openalex.org/W2065874620","https://openalex.org/W2077671836","https://openalex.org/W2080510044","https://openalex.org/W2081173396","https://openalex.org/W2092766667","https://openalex.org/W2096940779","https://openalex.org/W2097187642","https://openalex.org/W2099040294","https://openalex.org/W2103778975","https://openalex.org/W2110816244","https://openalex.org/W2114510657","https://openalex.org/W2115418322","https://openalex.org/W2117013761","https://openalex.org/W2117454157","https://openalex.org/W2127079031","https://openalex.org/W2128272594","https://openalex.org/W2142574980","https://openalex.org/W2146440075","https://openalex.org/W2154682055","https://openalex.org/W2157349345","https://openalex.org/W2163941765","https://openalex.org/W2166888255","https://openalex.org/W2168169162","https://openalex.org/W2168917739","https://openalex.org/W2264200285","https://openalex.org/W2330985710","https://openalex.org/W2334576825","https://openalex.org/W2334614461","https://openalex.org/W2401398746","https://openalex.org/W2410322445","https://openalex.org/W2419366312","https://openalex.org/W2462738560"],"related_works":["https://openalex.org/W2330985710","https://openalex.org/W2022779353","https://openalex.org/W2038855483","https://openalex.org/W2066005580","https://openalex.org/W2110730965","https://openalex.org/W2148478350","https://openalex.org/W2962972796","https://openalex.org/W4415168281","https://openalex.org/W4408538464","https://openalex.org/W4211133087"],"abstract_inverted_index":{"Head":[0],"and":[1,26,49,93,113,141,160,179,198],"neck":[2],"squamous":[3],"cell":[4,161],"carcinoma":[5],"(HNSCC)":[6],"is":[7,33,97],"the":[8,43,76,124,129,168],"fifth":[9],"most":[10],"common":[11],"cancer":[12],"in":[13,89,154,175],"men":[14],"with":[15,102],"an":[16],"incidence":[17],"of":[18,30,40,45,68,126,134,145],"about":[19],"780000":[20],"new":[21,52,121,196],"cases":[22],"per":[23],"year":[24],"worldwide":[25],"a":[27,34,37,63,86,99,132],"poor":[28],"rate":[29],"survival.":[31],"There":[32,96],"need":[35],"for":[36,42],"better":[38],"understanding":[39,125],"HNSCC,":[41],"development":[44],"rational":[46],"targeted":[47],"interventions":[48],"to":[50],"define":[51],"prognostic":[53],"or":[54,182],"diagnostic":[55],"markers.":[56],"To":[57],"address":[58],"these":[59],"needs,":[60],"we":[61,191],"performed":[62],"large-scale":[64],"differential":[65],"display":[66],"comparison":[67],"hypopharyngeal":[69],"HNSCCs":[70],"against":[71],"histologically":[72],"normal":[73,94],"tissue":[74],"from":[75],"same":[77],"patients.":[78],"We":[79],"have":[80,109,192],"identified":[81,193],"70":[82],"genes":[83,137,150,171,189],"that":[84,108,172,190],"exhibit":[85],"striking":[87],"difference":[88],"expression":[90,106],"between":[91],"tumours":[92],"tissues.":[95],"only":[98,174],"limited":[100],"overlap":[101],"other":[103,111],"HNSCC":[104],"gene":[105],"studies":[107],"used":[110],"techniques":[112],"more":[114],"heterogeneous":[115],"tumour":[116],"samples.":[117],"Our":[118],"results":[119],"provide":[120],"insights":[122],"into":[123],"HNSCC.":[127],"At":[128],"genome":[130,146],"level,":[131],"series":[133],"differentially":[135,187],"expressed":[136,188],"cluster":[138],"at":[139],"12p12-13":[140],"1q21,":[142],"two":[143],"hotspots":[144],"disruption.":[147],"The":[148,186],"known":[149],"share":[151],"functional":[152],"relationships":[153],"keratinocyte":[155],"differentiation,":[156],"angiogenesis,":[157],"immunology,":[158],"detoxification,":[159],"surface":[162],"receptors.":[163],"Of":[164],"particular":[165],"interest":[166],"are":[167,194],"13":[169],"'unknown'":[170],"exist":[173],"EST,":[176],"theoretical":[177],"cDNA":[178],"protein":[180],"databases,":[181],"as":[183],"chromosomal":[184],"locations.":[185],"potential":[195],"markers":[197],"therapeutic":[199],"targets.":[200]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}