{"id":"https://openalex.org/W2016850217","doi":"https://doi.org/10.1002/dmrr.673","title":"Achieving durable glucose control in the intensive care unit without hypoglycaemia : a new practical IV insulin protocol","display_name":"Achieving durable glucose control in the intensive care unit without hypoglycaemia : a new practical IV insulin protocol","publication_year":2006,"publication_date":"2006-07-28","ids":{"openalex":"https://openalex.org/W2016850217","doi":"https://doi.org/10.1002/dmrr.673","mag":"2016850217","pmid":"https://pubmed.ncbi.nlm.nih.gov/16874843"},"language":"en","primary_location":{"id":"doi:10.1002/dmrr.673","doi":"https://doi.org/10.1002/dmrr.673","is_oa":false,"landing_page_url":"https://doi.org/10.1002/dmrr.673","pdf_url":null,"source":{"id":"https://openalex.org/S83251063","display_name":"Diabetes/Metabolism Research and Reviews","issn_l":"1520-7552","issn":["1520-7552","1520-7560"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes/Metabolism Research and Reviews","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032597483","display_name":"Michael S. Balkin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801317995","display_name":"Nassau University Medical Center","ror":"https://ror.org/03cc0mm23","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801317995"]},{"id":"https://openalex.org/I4210122508","display_name":"Huntington Hospital","ror":"https://ror.org/039dabd75","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1302444339","https://openalex.org/I4210122508"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Michael Balkin","raw_affiliation_strings":["Department of Medicine, Huntington Hospital, Huntington, NY 11743, USA. mbalkin@mac.com","Department of Medicine, Huntington Hospital, 270 Park Avenue, Huntington. New York, USA","Department of Medicine, Nassau University Medical Center, 2201 Hempstead Turnpike, East Meadow, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Huntington Hospital, Huntington, NY 11743, USA. mbalkin@mac.com","institution_ids":["https://openalex.org/I4210122508"]},{"raw_affiliation_string":"Department of Medicine, Huntington Hospital, 270 Park Avenue, Huntington. New York, USA","institution_ids":["https://openalex.org/I4210122508"]},{"raw_affiliation_string":"Department of Medicine, Nassau University Medical Center, 2201 Hempstead Turnpike, East Meadow, New York, USA","institution_ids":["https://openalex.org/I2801317995"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064107722","display_name":"Charles Mascioli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210122508","display_name":"Huntington Hospital","ror":"https://ror.org/039dabd75","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1302444339","https://openalex.org/I4210122508"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charles Mascioli","raw_affiliation_strings":["Department of Medicine, Huntington Hospital, 270 Park Avenue, Huntington. New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Huntington Hospital, 270 Park Avenue, Huntington. New York, USA","institution_ids":["https://openalex.org/I4210122508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023921323","display_name":"Virginia Smith","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210122508","display_name":"Huntington Hospital","ror":"https://ror.org/039dabd75","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1302444339","https://openalex.org/I4210122508"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Virginia Smith","raw_affiliation_strings":["Division of Nursing, Huntington Hospital, 270 Park Avenue, Huntington, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nursing, Huntington Hospital, 270 Park Avenue, Huntington, New York, USA","institution_ids":["https://openalex.org/I4210122508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016755564","display_name":"Hicham Al-Nachawati","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801317995","display_name":"Nassau University Medical Center","ror":"https://ror.org/03cc0mm23","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801317995"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hicham Alnachawati","raw_affiliation_strings":["Department of Medicine, Nassau University Medical Center, 2201 Hempstead Turnpike, East Meadow, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Nassau University Medical Center, 2201 Hempstead Turnpike, East Meadow, New York, USA","institution_ids":["https://openalex.org/I2801317995"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019394409","display_name":"Sandeep Mehrishi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801317995","display_name":"Nassau University Medical Center","ror":"https://ror.org/03cc0mm23","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801317995"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sandeep Mehrishi","raw_affiliation_strings":["Department of Medicine, Nassau University Medical Center, 2201 Hempstead Turnpike, East Meadow, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Nassau University Medical Center, 2201 Hempstead Turnpike, East Meadow, New York, USA","institution_ids":["https://openalex.org/I2801317995"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038294711","display_name":"Ghulam Saydain","orcid":"https://orcid.org/0000-0002-3823-9848","observed_orcids":["https://orcid.org/0000-0002-3823-9848"]},"institutions":[{"id":"https://openalex.org/I2801317995","display_name":"Nassau University Medical Center","ror":"https://ror.org/03cc0mm23","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801317995"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ghulam Saydain","raw_affiliation_strings":["Department of Medicine, Nassau University Medical Center, 2201 Hempstead Turnpike, East Meadow, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Nassau University Medical Center, 2201 Hempstead Turnpike, East Meadow, New York, USA","institution_ids":["https://openalex.org/I2801317995"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022108247","display_name":"Helen Slone","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Helen Slone","raw_affiliation_strings":["Department of Medicine, South Jersey Regional Medical Center, 1505 West Sherman Avenue, Vineland, NJ, 08360, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, South Jersey Regional Medical Center, 1505 West Sherman Avenue, Vineland, NJ, 08360, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059710826","display_name":"Joseph Alessandrini","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Joseph Alessandrini","raw_affiliation_strings":["Department of Pharmacy, South Jersey Regional Medical Center, 1505 West Sherman Avenue, Vineland, NJ, 08360, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, South Jersey Regional Medical Center, 1505 West Sherman Avenue, Vineland, NJ, 08360, USA","institution_ids":[]}]},{"author_position":"last","author":{"id":null,"display_name":"Lawrence Brown","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210122508","display_name":"Huntington Hospital","ror":"https://ror.org/039dabd75","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1302444339","https://openalex.org/I4210122508"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lawrence Brown","raw_affiliation_strings":["Department of Medicine, Huntington Hospital, 270 Park Avenue, Huntington. New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Huntington Hospital, 270 Park Avenue, Huntington. New York, USA","institution_ids":["https://openalex.org/I4210122508"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5032597483"],"corresponding_institution_ids":["https://openalex.org/I2801317995","https://openalex.org/I4210122508"],"apc_list":{"value":4780,"currency":"USD","value_usd":4780},"apc_paid":null,"fwci":2.9434,"has_fulltext":false,"cited_by_count":22,"citation_normalized_percentile":{"value":0.91249786,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"23","issue":"1","first_page":"49","last_page":"55"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11623","display_name":"Hyperglycemia and glycemic control in critically ill and hospitalized patients","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11623","display_name":"Hyperglycemia and glycemic control in critically ill and hospitalized patients","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10858","display_name":"Clinical Nutrition and Gastroenterology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intensive-care-unit","display_name":"intensive care unit","score":0.722000002861023},{"id":"https://openalex.org/keywords/hyperglycemia","display_name":"hyperglycemia","score":0.796999990940094},{"id":"https://openalex.org/keywords/insulin-infusion-protocol","display_name":"insulin infusion protocol","score":0.5080000162124634},{"id":"https://openalex.org/keywords/glycemic-control","display_name":"glycemic control","score":0.703000009059906},{"id":"https://openalex.org/keywords/hypoglycemia-prevention","display_name":"hypoglycemia prevention","score":0.9419999718666077},{"id":"https://openalex.org/keywords/critically-ill-patients","display_name":"critically ill patients","score":0.7710000276565552},{"id":"https://openalex.org/keywords/blood-glucose-meters","display_name":"blood glucose meters","score":0.3050000071525574}],"concepts":[{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.7714356184005737},{"id":"https://openalex.org/C2780385302","wikidata":"https://www.wikidata.org/wiki/Q367158","display_name":"Protocol (science)","level":3,"score":0.6216200590133667},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5443264245986938},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3512643575668335},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.33587759733200073},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.06424364447593689},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002985","descriptor_name":"Clinical Protocols","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004334","descriptor_name":"Drug Administration Schedule","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007003","descriptor_name":"Hypoglycemia","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D007262","descriptor_name":"Infusions, Intravenous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007328","descriptor_name":"Insulin","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D007362","descriptor_name":"Intensive Care Units","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/dmrr.673","doi":"https://doi.org/10.1002/dmrr.673","is_oa":false,"landing_page_url":"https://doi.org/10.1002/dmrr.673","pdf_url":null,"source":{"id":"https://openalex.org/S83251063","display_name":"Diabetes/Metabolism Research and Reviews","issn_l":"1520-7552","issn":["1520-7552","1520-7560"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes/Metabolism Research and Reviews","raw_type":"journal-article"},{"id":"pmid:16874843","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16874843","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes/metabolism research and reviews","raw_type":"Clinical Trial"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9907000064849854}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320313816","display_name":"NorthShore University HealthSystem","ror":"https://ror.org/04tpp9d61"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W1972352298","https://openalex.org/W1973956216","https://openalex.org/W1980717583","https://openalex.org/W1990893369","https://openalex.org/W1992834800","https://openalex.org/W2007852978","https://openalex.org/W2008545806","https://openalex.org/W2027002476","https://openalex.org/W2035037946","https://openalex.org/W2040454056","https://openalex.org/W2053700636","https://openalex.org/W2066186983","https://openalex.org/W2066874270","https://openalex.org/W2070200475","https://openalex.org/W2088624742","https://openalex.org/W2092998122","https://openalex.org/W2107075639","https://openalex.org/W2110831768","https://openalex.org/W2115285670","https://openalex.org/W2133803133","https://openalex.org/W2156803016","https://openalex.org/W2159423219","https://openalex.org/W2162268531","https://openalex.org/W2163567504","https://openalex.org/W2167287087","https://openalex.org/W2169968309","https://openalex.org/W2173660670","https://openalex.org/W4245690870"],"related_works":["https://openalex.org/W2136520537","https://openalex.org/W1978911821","https://openalex.org/W2021004917","https://openalex.org/W2593616704","https://openalex.org/W2087978429","https://openalex.org/W2971783281","https://openalex.org/W1996236894","https://openalex.org/W2120281962","https://openalex.org/W2109060914","https://openalex.org/W1511861283"],"abstract_inverted_index":{"BACKGROUND:":[0],"Hyperglycaemia":[1],"occurs":[2],"in":[3,11,45,119,198],"a":[4,49,70,82],"substantial":[5],"portion":[6],"of":[7,18,78,99,169,184,251],"critically":[8],"ill":[9],"patients":[10],"our":[12],"intensive":[13],"care":[14],"units.":[15],"Near":[16],"normalization":[17],"elevated":[19],"blood":[20,105,137],"glucose":[21,66,106,133,138,171],"levels":[22],"with":[23,69],"IV":[24,32,214,230],"insulin":[25,33,90,120,177,215,231],"may":[26],"improve":[27],"outcome.":[28],"However,":[29],"currently":[30],"published":[31],"protocol":[34,50,80,161,201,207,216,232,241],"are":[35,39,128],"not":[36,193],"ideal;":[37],"most":[38],"relatively":[40],"complex":[41],"and":[42,102,146,176,195,222,253],"often":[43],"result":[44],"hypoglycaemia.":[46,73],"We":[47],"designed":[48],"that":[51,233],"would":[52],"be":[53,95,180],"practical":[54,229],"to":[55,63,94,179],"use":[56,252],"while":[57],"incorporating":[58],"the":[59,79,85,100,103,109,112,116,154,160,185,188,200,212,218],"necessary":[60],"complexities":[61],"required":[62,117,194],"achieve":[64],"good":[65],"control,":[67],"coupled":[68],"low":[71],"incidence":[72],"METHODS:":[74],"The":[75,97,131,156,240],"essential":[76],"part":[77],"is":[81,93,238],"matrix":[83,110],"specifying":[84],"amount":[86],"by":[87,136],"which":[88],"an":[89],"flow":[91,121],"rate":[92],"changed.":[96],"intersection":[98],"current":[101],"previous":[104],"values":[107,172],"on":[108,153,159,187],"locates":[111],"appropriate":[113],"cell":[114],"containing":[115],"change":[118],"rate.":[122],"No":[123],"additional":[124],"calculations":[125],"or":[126],"tables":[127],"required.":[129],"RESULTS:":[130],"initial":[132],"level":[134],"obtained":[135],"meter":[139],"(BGM)":[140],"averaged":[141],"253.5":[142],"+/-":[143,164],"95.6":[144],"mg/dL":[145,175],"fell":[147],"below":[148],"140":[149],"within":[150],"9.3":[151],"h":[152],"protocol.":[155,189],"average":[157],"BGM":[158],"was":[162,192,202],"133.5":[163],"43.9":[165],"mg/dL.":[166],"Only":[167],"0.09%":[168],"all":[170],"were":[173],"<40":[174],"had":[178],"held":[181],"only":[182],"2.2%":[183],"time":[186],"Physician":[190],"input":[191],"nursing":[196],"accuracy":[197],"applying":[199],"greater":[203],"than":[204],"94%.":[205],"This":[206],"has":[208,234,242],"been":[209,235,243],"adopted":[210],"as":[211],"default":[213],"for":[217],"NorthShore-LIJ":[219],"Health":[220],"System":[221],"several":[223],"other":[224],"medical":[225],"centers.":[226],"CONCLUSION:":[227],"A":[228],"extensively":[236],"tested":[237],"presented.":[239],"implemented":[244],"at":[245],"multiple":[246],"institutions":[247],"indicating":[248],"its":[249],"ease":[250],"excellent":[254],"results.":[255]},"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}