{"id":"https://openalex.org/W2016791397","doi":"https://doi.org/10.1007/bf02637070","title":"Fatty acids and Schizophrenia","display_name":"Fatty acids and Schizophrenia","publication_year":1996,"publication_date":"1996-01-01","ids":{"openalex":"https://openalex.org/W2016791397","doi":"https://doi.org/10.1007/bf02637070","mag":"2016791397","pmid":"https://pubmed.ncbi.nlm.nih.gov/8729113"},"language":"en","primary_location":{"id":"doi:10.1007/bf02637070","doi":"https://doi.org/10.1007/bf02637070","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf02637070","pdf_url":null,"source":{"id":"https://openalex.org/S115623499","display_name":"Lipids","issn_l":"0024-4201","issn":["0024-4201","1558-9307"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lipids","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027014874","display_name":"Jonathan D. E. Laugharne","orcid":"https://orcid.org/0009-0003-9511-6099","observed_orcids":["https://orcid.org/0009-0003-9511-6099"]},"institutions":[{"id":"https://openalex.org/I2801759359","display_name":"Northern General Hospital","ror":"https://ror.org/05r409z22","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801759359","https://openalex.org/I4210102902"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"J. D. E. Laugharne","raw_affiliation_strings":["University Department of Psychiatry Northern General Hospital Herries Road Sheffield S5 7AU UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Department of Psychiatry Northern General Hospital Herries Road Sheffield S5 7AU UK","institution_ids":["https://openalex.org/I2801759359"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027077488","display_name":"Jan E. Mellor","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801759359","display_name":"Northern General Hospital","ror":"https://ror.org/05r409z22","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801759359","https://openalex.org/I4210102902"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"J. E. Mellor","raw_affiliation_strings":["University Department of Psychiatry Northern General Hospital Herries Road Sheffield S5 7AU UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Department of Psychiatry Northern General Hospital Herries Road Sheffield S5 7AU UK","institution_ids":["https://openalex.org/I2801759359"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038274792","display_name":"Malcolm Peet","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801759359","display_name":"Northern General Hospital","ror":"https://ror.org/05r409z22","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801759359","https://openalex.org/I4210102902"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"M. Peet","raw_affiliation_strings":["University Department of Psychiatry Northern General Hospital Herries Road Sheffield S5 7AU UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Department of Psychiatry Northern General Hospital Herries Road Sheffield S5 7AU UK","institution_ids":["https://openalex.org/I2801759359"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I2801759359"],"apc_list":{"value":3589,"currency":"USD","value_usd":3589},"apc_paid":null,"fwci":2.1186,"has_fulltext":false,"cited_by_count":113,"citation_normalized_percentile":{"value":0.86358193,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"31","issue":"1Part2","first_page":"S163","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10387","display_name":"Fatty Acid Research and Health","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10387","display_name":"Fatty Acid Research and Health","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11337","display_name":"Tryptophan and brain disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2803","display_name":"Biological Psychiatry"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/schizophrenia","display_name":"schizophrenia","score":0.9990000128746033},{"id":"https://openalex.org/keywords/omega-3-fatty-acids","display_name":"omega-3 fatty acids","score":0.8880000114440918},{"id":"https://openalex.org/keywords/omega-6-fatty-acids","display_name":"omega-6 fatty acids","score":0.968999981880188},{"id":"https://openalex.org/keywords/arachidonic-acid","display_name":"arachidonic acid","score":0.984000027179718},{"id":"https://openalex.org/keywords/docosahexaenoic-acid","display_name":"docosahexaenoic acid","score":1.0},{"id":"https://openalex.org/keywords/fish-oil-supplementation","display_name":"fish oil supplementation","score":0.878000020980835},{"id":"https://openalex.org/keywords/dietary-fatty-acid-intake","display_name":"dietary fatty acid intake","score":0.9210000038146973},{"id":"https://openalex.org/keywords/symptom-severity","display_name":"symptom severity","score":0.7950000166893005},{"id":"https://openalex.org/keywords/cell-membrane-fatty-acid-composition","display_name":"cell membrane fatty acid composition","score":0.7649999856948853}],"concepts":[{"id":"https://openalex.org/C2777171753","wikidata":"https://www.wikidata.org/wiki/Q423345","display_name":"Docosahexaenoic acid","level":4,"score":0.7461154460906982},{"id":"https://openalex.org/C2776412080","wikidata":"https://www.wikidata.org/wiki/Q7431605","display_name":"Schizophrenia (object-oriented programming)","level":2,"score":0.6767029166221619},{"id":"https://openalex.org/C543025807","wikidata":"https://www.wikidata.org/wiki/Q61476","display_name":"Fatty acid","level":2,"score":0.6359557509422302},{"id":"https://openalex.org/C2778078955","wikidata":"https://www.wikidata.org/wiki/Q407699","display_name":"Arachidonic acid","level":3,"score":0.6141126751899719},{"id":"https://openalex.org/C382228","wikidata":"https://www.wikidata.org/wiki/Q849994","display_name":"Clinical chemistry","level":2,"score":0.6124359965324402},{"id":"https://openalex.org/C22894154","wikidata":"https://www.wikidata.org/wiki/Q15483409","display_name":"Lipidology","level":3,"score":0.5946321487426758},{"id":"https://openalex.org/C50965678","wikidata":"https://www.wikidata.org/wiki/Q2724302","display_name":"Abnormality","level":2,"score":0.5626524686813354},{"id":"https://openalex.org/C19038510","wikidata":"https://www.wikidata.org/wiki/Q2005087","display_name":"Polyunsaturated fatty acid","level":3,"score":0.5466251969337463},{"id":"https://openalex.org/C2779946292","wikidata":"https://www.wikidata.org/wiki/Q1786125","display_name":"Fish oil","level":3,"score":0.48531574010849},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3940461277961731},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.37692636251449585},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.37325721979141235},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.37076056003570557},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3225589096546173},{"id":"https://openalex.org/C2909208804","wikidata":"https://www.wikidata.org/wiki/Q127282","display_name":"Fish <Actinopterygii>","level":2,"score":0.20505857467651367},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.16635087132453918},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0},{"id":"https://openalex.org/C505870484","wikidata":"https://www.wikidata.org/wiki/Q180538","display_name":"Fishery","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D004910","descriptor_name":"Erythrocyte Membrane","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005227","descriptor_name":"Fatty Acids","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D005231","descriptor_name":"Fatty Acids, Unsaturated","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012559","descriptor_name":"Schizophrenia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D015227","descriptor_name":"Lipid Peroxidation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015525","descriptor_name":"Fatty Acids, Omega-3","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D043371","descriptor_name":"Fatty Acids, Omega-6","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/bf02637070","doi":"https://doi.org/10.1007/bf02637070","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf02637070","pdf_url":null,"source":{"id":"https://openalex.org/S115623499","display_name":"Lipids","issn_l":"0024-4201","issn":["0024-4201","1558-9307"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lipids","raw_type":"journal-article"},{"id":"pmid:8729113","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8729113","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lipids","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W198402614","https://openalex.org/W1515078102","https://openalex.org/W1735535434","https://openalex.org/W1925421457","https://openalex.org/W1964613812","https://openalex.org/W1969217470","https://openalex.org/W1976700610","https://openalex.org/W1983398680","https://openalex.org/W1991506996","https://openalex.org/W2001808486","https://openalex.org/W2005924604","https://openalex.org/W2024802074","https://openalex.org/W2028625546","https://openalex.org/W2040088895","https://openalex.org/W2046320380","https://openalex.org/W2061033236","https://openalex.org/W2063267379","https://openalex.org/W2064915811","https://openalex.org/W2070106764","https://openalex.org/W2078279764","https://openalex.org/W2080258840","https://openalex.org/W2080927832","https://openalex.org/W2087962937","https://openalex.org/W2091928537","https://openalex.org/W2093320011","https://openalex.org/W2093960552","https://openalex.org/W2103513447","https://openalex.org/W2108291548","https://openalex.org/W2147575330","https://openalex.org/W2156733305","https://openalex.org/W2409711503","https://openalex.org/W2410265771","https://openalex.org/W2886809532"],"related_works":["https://openalex.org/W2119138947","https://openalex.org/W2087962937","https://openalex.org/W2156733305","https://openalex.org/W1996015317","https://openalex.org/W2004868363","https://openalex.org/W2121300431","https://openalex.org/W2059809898","https://openalex.org/W2074237270","https://openalex.org/W2004648621","https://openalex.org/W2517660564"],"abstract_inverted_index":{"In":[0,36],"a":[1,37,110],"controlled":[2],"study":[3],"of":[4,16,45,56,76,97,109,113,117],"red":[5,102],"cell":[6,103,121],"membrane":[7,122],"fatty":[8,17,46,58,99,123],"acids":[9,18,59,100],"in":[10,49,85,101,120,126],"patients":[11],"with":[12,62,71],"schizophrenia,":[13],"substantial":[14],"depletions":[15],"from":[19],"both":[20],"the":[21,94],"n-6":[22],"and":[23,30,144],"n-3":[24,57,98],"series":[25],"were":[26,33],"demonstrated.":[27],"Arachidonic":[28],"acid":[29,32,47,124],"docosahexaenoic":[31],"particularly":[34],"depleted.":[35],"separate":[38],"study,":[39],"dietary":[40,134],"analysis":[41],"revealed":[42],"no":[43],"deficiency":[44],"intake":[48,55],"this":[50],"patient":[51],"group,":[52],"but":[53],"greater":[54],"was":[60,91],"associated":[61],"less":[63],"severe":[64],"symptomatology.":[65],"Dietary":[66],"supplementation":[67],"for":[68,131],"six":[69],"weeks":[70],"10":[72],"g":[73],"per":[74],"day":[75],"concentrated":[77],"fish":[78],"oil":[79],"(MaxEPA)":[80],"led":[81],"to":[82,93,136],"significant":[83],"improvement":[84,90],"schizophrenic":[86],"symptoms.":[87],"This":[88],"clinical":[89],"related":[92],"increased":[95],"level":[96],"membranes.":[104],"These":[105],"findings":[106],"form":[107],"part":[108],"growing":[111],"body":[112],"research":[114],"data":[115],"suggestive":[116],"an":[118,139],"abnormality":[119,140],"composition":[125],"schizophrenia.":[127],"The":[128],"preliminary":[129],"evidence":[130],"clinically":[132],"effective":[133],"manipulation":[135],"correct":[137],"such":[138],"opens":[141],"up":[142],"novel":[143],"exciting":[145],"therapeutic":[146],"possibilities.":[147]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}