{"id":"https://openalex.org/W2016774778","doi":"https://doi.org/10.1002/jor.20853","title":"Temporal growth factor release from platelet\u2010rich plasma, trehalose lyophilized platelets, and bone marrow aspirate and their effect on tendon and ligament gene expression","display_name":"Temporal growth factor release from platelet\u2010rich plasma, trehalose lyophilized platelets, and bone marrow aspirate and their effect on tendon and ligament gene expression","publication_year":2009,"publication_date":"2009-01-23","ids":{"openalex":"https://openalex.org/W2016774778","doi":"https://doi.org/10.1002/jor.20853","mag":"2016774778","pmid":"https://pubmed.ncbi.nlm.nih.gov/19170097"},"language":"en","primary_location":{"id":"doi:10.1002/jor.20853","doi":"https://doi.org/10.1002/jor.20853","is_oa":true,"landing_page_url":"https://doi.org/10.1002/jor.20853","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jor.20853","source":{"id":"https://openalex.org/S12558119","display_name":"Journal of Orthopaedic Research\u00ae","issn_l":"0736-0266","issn":["0736-0266","1554-527X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Orthopaedic Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jor.20853","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058938419","display_name":"Taralyn M. McCarrel","orcid":"https://orcid.org/0000-0002-3124-4054","observed_orcids":["https://orcid.org/0000-0002-3124-4054"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Taralyn McCarrel","raw_affiliation_strings":["Department of Clinical Sciences, Cornell University, Ithaca, New York 14853, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Sciences, Cornell University, Ithaca, New York 14853, USA","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059515326","display_name":"Lisa A. Fortier","orcid":"https://orcid.org/0000-0003-1072-5059","observed_orcids":["https://orcid.org/0000-0003-1072-5059"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Lisa Fortier","raw_affiliation_strings":["Department of Clinical Sciences, Cornell University, Ithaca, New York 14853","Department of Clinical Sciences, Cornell University, Ithaca, New York 14853. T: 607\u2010253\u20103102; F: 607\u2010253\u20103497"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Sciences, Cornell University, Ithaca, New York 14853","institution_ids":["https://openalex.org/I205783295"]},{"raw_affiliation_string":"Department of Clinical Sciences, Cornell University, Ithaca, New York 14853. T: 607\u2010253\u20103102; F: 607\u2010253\u20103497","institution_ids":["https://openalex.org/I205783295"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5059515326"],"corresponding_institution_ids":["https://openalex.org/I205783295"],"apc_list":{"value":3970,"currency":"USD","value_usd":3970},"apc_paid":null,"fwci":19.2479,"has_fulltext":true,"cited_by_count":394,"citation_normalized_percentile":{"value":0.99823899,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"27","issue":"8","first_page":"1033","last_page":"1042"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11570","display_name":"Periodontal Regeneration and Treatments","score":0.5752000212669373,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11570","display_name":"Periodontal Regeneration and Treatments","score":0.5752000212669373,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11068","display_name":"Tendon Structure and Treatment","score":0.423799991607666,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10630","display_name":"Orthopedic Surgery and Rehabilitation","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/platelet-rich-plasma","display_name":"platelet-rich plasma","score":1.0},{"id":"https://openalex.org/keywords/bone-marrow-aspirate","display_name":"bone marrow aspirate","score":0.9929999709129333},{"id":"https://openalex.org/keywords/growth-factor-release","display_name":"growth factor release","score":0.9340000152587891},{"id":"https://openalex.org/keywords/tendon-regeneration","display_name":"tendon regeneration","score":0.8320000171661377},{"id":"https://openalex.org/keywords/ligament-regeneration","display_name":"ligament regeneration","score":0.9900000095367432},{"id":"https://openalex.org/keywords/flexor-digitorum-superficialis-tendon","display_name":"flexor digitorum superficialis tendon","score":0.8949999809265137},{"id":"https://openalex.org/keywords/suspensory-ligament","display_name":"suspensory ligament","score":0.984000027179718},{"id":"https://openalex.org/keywords/tgf-beta1","display_name":"TGF-\u03b21","score":0.8809999823570251},{"id":"https://openalex.org/keywords/pdgf-bb","display_name":"PDGF-BB","score":0.996999979019165},{"id":"https://openalex.org/keywords/collagen-type-i-and-iii","display_name":"collagen I and III","score":0.7879999876022339},{"id":"https://openalex.org/keywords/cartilage-oligomeric-matrix-protein","display_name":"cartilage oligomeric matrix protein","score":0.9079999923706055},{"id":"https://openalex.org/keywords/decorin","display_name":"decorin","score":0.9810000061988831},{"id":"https://openalex.org/keywords/matrix-metalloproteinases","display_name":"matrix metalloproteinases","score":0.8849999904632568},{"id":"https://openalex.org/keywords/tendinitis","display_name":"tendinitis","score":0.8849999904632568},{"id":"https://openalex.org/keywords/desmitis","display_name":"desmitis","score":0.8389999866485596},{"id":"https://openalex.org/keywords/gene-expression","display_name":"gene expression","score":0.5699999928474426}],"concepts":[{"id":"https://openalex.org/C2779794767","wikidata":"https://www.wikidata.org/wiki/Q18248676","display_name":"Decorin","level":4,"score":0.7968474626541138},{"id":"https://openalex.org/C2780076745","wikidata":"https://www.wikidata.org/wiki/Q613879","display_name":"Platelet-rich plasma","level":3,"score":0.6788625121116638},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6226850152015686},{"id":"https://openalex.org/C89560881","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet","level":2,"score":0.559392511844635},{"id":"https://openalex.org/C2778232976","wikidata":"https://www.wikidata.org/wiki/Q15320335","display_name":"Cartilage oligomeric matrix protein","level":4,"score":0.5555571913719177},{"id":"https://openalex.org/C2775960820","wikidata":"https://www.wikidata.org/wiki/Q408378","display_name":"Growth factor","level":3,"score":0.5198041200637817},{"id":"https://openalex.org/C180361614","wikidata":"https://www.wikidata.org/wiki/Q7202242","display_name":"Platelet-derived growth factor receptor","level":4,"score":0.4893571734428406},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.4665047526359558},{"id":"https://openalex.org/C2779753412","wikidata":"https://www.wikidata.org/wiki/Q39888","display_name":"Ligament","level":2,"score":0.46463659405708313},{"id":"https://openalex.org/C109523444","wikidata":"https://www.wikidata.org/wiki/Q424216","display_name":"Matrix metalloproteinase","level":2,"score":0.4618794620037079},{"id":"https://openalex.org/C2780105995","wikidata":"https://www.wikidata.org/wiki/Q232358","display_name":"Tendon","level":2,"score":0.45819032192230225},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.32921797037124634},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3231028616428375},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.29946136474609375},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.24817797541618347},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.23071354627609253},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.19781160354614258},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1737588346004486},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1666698455810547},{"id":"https://openalex.org/C2776164576","wikidata":"https://www.wikidata.org/wiki/Q62736","display_name":"Osteoarthritis","level":3,"score":0.14326107501983643},{"id":"https://openalex.org/C2779335624","wikidata":"https://www.wikidata.org/wiki/Q407976","display_name":"Proteoglycan","level":3,"score":0.07013577222824097},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000077214","descriptor_name":"Becaplermin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001792","descriptor_name":"Blood Platelets","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D001792","descriptor_name":"Blood Platelets","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001853","descriptor_name":"Bone Marrow","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006736","descriptor_name":"Horses","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008022","descriptor_name":"Ligaments","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010982","descriptor_name":"Platelet-Derived Growth Factor","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013710","descriptor_name":"Tendons","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014199","descriptor_name":"Trehalose","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D019278","descriptor_name":"Matrix Metalloproteinase 3","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D020574","descriptor_name":"Proto-Oncogene Proteins c-sis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D024042","descriptor_name":"Collagen Type I","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D024061","descriptor_name":"Collagen Type III","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D036341","descriptor_name":"Intercellular Signaling Peptides and Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D053509","descriptor_name":"Matrix Metalloproteinase 13","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D053657","descriptor_name":"Platelet-Rich Plasma","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D053773","descriptor_name":"Transforming Growth Factor beta1","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/jor.20853","doi":"https://doi.org/10.1002/jor.20853","is_oa":true,"landing_page_url":"https://doi.org/10.1002/jor.20853","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jor.20853","source":{"id":"https://openalex.org/S12558119","display_name":"Journal of Orthopaedic Research\u00ae","issn_l":"0736-0266","issn":["0736-0266","1554-527X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Orthopaedic Research","raw_type":"journal-article"},{"id":"pmid:19170097","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19170097","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of orthopaedic research : official publication of the Orthopaedic Research Society","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1002/jor.20853","doi":"https://doi.org/10.1002/jor.20853","is_oa":true,"landing_page_url":"https://doi.org/10.1002/jor.20853","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jor.20853","source":{"id":"https://openalex.org/S12558119","display_name":"Journal of Orthopaedic Research\u00ae","issn_l":"0736-0266","issn":["0736-0266","1554-527X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Orthopaedic Research","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320311918","display_name":"Harry M. Zweig Memorial Fund for Equine Research","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2016774778.pdf","grobid_xml":"https://content.openalex.org/works/W2016774778.grobid-xml"},"referenced_works_count":61,"referenced_works":["https://openalex.org/W89623994","https://openalex.org/W102582905","https://openalex.org/W112651359","https://openalex.org/W132379413","https://openalex.org/W161150634","https://openalex.org/W1493119447","https://openalex.org/W1597610606","https://openalex.org/W1739491659","https://openalex.org/W1963877340","https://openalex.org/W1966509471","https://openalex.org/W1967777610","https://openalex.org/W1968639212","https://openalex.org/W1969658034","https://openalex.org/W1970672986","https://openalex.org/W1995869085","https://openalex.org/W2004809001","https://openalex.org/W2013301121","https://openalex.org/W2013965303","https://openalex.org/W2019169241","https://openalex.org/W2023602786","https://openalex.org/W2028277256","https://openalex.org/W2032667301","https://openalex.org/W2034786302","https://openalex.org/W2038843643","https://openalex.org/W2040152839","https://openalex.org/W2044862989","https://openalex.org/W2047311691","https://openalex.org/W2051137064","https://openalex.org/W2052511585","https://openalex.org/W2055530303","https://openalex.org/W2058195651","https://openalex.org/W2060823909","https://openalex.org/W2066448656","https://openalex.org/W2072481490","https://openalex.org/W2077696617","https://openalex.org/W2081707753","https://openalex.org/W2082308378","https://openalex.org/W2084981545","https://openalex.org/W2087189345","https://openalex.org/W2091362907","https://openalex.org/W2093032731","https://openalex.org/W2093044729","https://openalex.org/W2096005542","https://openalex.org/W2096171902","https://openalex.org/W2098964232","https://openalex.org/W2107277218","https://openalex.org/W2107931933","https://openalex.org/W2112293155","https://openalex.org/W2113408423","https://openalex.org/W2113788262","https://openalex.org/W2122366747","https://openalex.org/W2131355536","https://openalex.org/W2136871488","https://openalex.org/W2142527986","https://openalex.org/W2148373785","https://openalex.org/W2163780750","https://openalex.org/W2164563725","https://openalex.org/W2181341389","https://openalex.org/W2201141685","https://openalex.org/W2341487655","https://openalex.org/W2904007544"],"related_works":["https://openalex.org/W2058195651","https://openalex.org/W2164916690","https://openalex.org/W2783790465","https://openalex.org/W2121620043","https://openalex.org/W2805026561","https://openalex.org/W2076891661","https://openalex.org/W1984461161","https://openalex.org/W2113048278","https://openalex.org/W2118727609","https://openalex.org/W2058143270"],"abstract_inverted_index":{"Platelet-rich":[0],"plasma":[1,79],"(PRP)":[2],"has":[3],"generated":[4],"substantial":[5],"interest":[6],"for":[7,105,243],"tendon":[8,48,68],"and":[9,38,43,49,54,58,63,70,88,96,109,119,122,129,136,148,156,164,173,182,185,199,201,207,219,221,230,241,247],"ligament":[10,50,72],"regeneration":[11],"because":[12],"of":[13,17,29,99,197,227,239,245],"the":[14,26],"high":[15],"concentrations":[16,90,131,158],"growth":[18,30],"factors":[19,31],"in":[20,77,80,134,143,146,150,167,179,236],"platelet":[21,40,157],"alpha-granules.":[22],"This":[23],"study":[24],"compared":[25],"temporal":[27],"release":[28],"from":[32],"bone":[33],"marrow":[34],"aspirate":[35],"(BMA),":[36],"PRP,":[37,84,147],"lyophilized":[39],"product":[41],"(PP),":[42],"measured":[44],"their":[45],"effects":[46],"on":[47],"gene":[51,187],"expression.":[52,176,188],"Blood":[53],"BMA":[55,177],"were":[56,75,91,132,159],"collected":[57],"processed":[59],"to":[60],"yield":[61],"PRP":[62,135,165,240],"plasma.":[64],"Flexor":[65],"digitorum":[66],"superficialis":[67],"(FDS)":[69],"suspensory":[71],"(SL)":[73],"explants":[74],"cultured":[76],"10%":[78],"DMEM":[81],"(control),":[82],"BMA,":[83,144],"or":[85],"PP.":[86,137],"TGF-beta1":[87,128,155],"PDGF-BB":[89,130],"determined":[92],"at":[93],"0,":[94],"24,":[95],"96":[97],"h":[98],"culture":[100],"using":[101],"ELISA.":[102],"Quantitative":[103],"RT-PCR":[104],"collagen":[106],"types":[107],"I":[108],"III":[110],"(COL1A1,":[111],"COL3A1),":[112],"cartilage":[113],"oligomeric":[114],"matrix":[115,120],"protein":[116],"(COMP),":[117],"decorin,":[118],"metalloproteinases-3":[121],"13":[123],"(MMP-3,":[124],"MMP-13)":[125],"was":[126,141,191,213],"performed.":[127],"highest":[133],"Growth":[138],"factor":[139],"quantity":[140],"unchanged":[142],"increased":[145,168,171,183],"decreased":[149,174,180],"PP":[151,163,242],"over":[152],"4":[153],"days.":[154],"positively":[160,192,214],"correlated.":[161],"Lyophilized":[162],"resulted":[166,178],"COL1A1:COL3A1":[169],"ratio,":[170],"COMP,":[172,200,229],"MMP-13":[175,186],"COMP":[181],"MMP-3":[184],"Platelet":[189],"concentration":[190,212],"correlated":[193,203,215,223],"with":[194,204,216,224],"COL1A1,":[195],"ratio":[196,226],"COL1A1:COL3A1,":[198,228],"negatively":[202,222],"COL3A1,":[205,217],"MMP-13,":[206],"MMP-3.":[208],"White":[209],"blood":[210],"cell":[211],"MMP3,":[218],"MMP13,":[220],"a":[225],"decorin.":[231],"These":[232],"findings":[233],"support":[234],"further":[235],"vivo":[237],"investigation":[238],"treatment":[244],"tendonitis":[246],"desmitis.":[248]},"counts_by_year":[{"year":2026,"cited_by_count":11},{"year":2025,"cited_by_count":20},{"year":2024,"cited_by_count":22},{"year":2023,"cited_by_count":17},{"year":2022,"cited_by_count":19},{"year":2021,"cited_by_count":24},{"year":2020,"cited_by_count":22},{"year":2019,"cited_by_count":26},{"year":2018,"cited_by_count":27},{"year":2017,"cited_by_count":21},{"year":2016,"cited_by_count":23},{"year":2015,"cited_by_count":32},{"year":2014,"cited_by_count":30},{"year":2013,"cited_by_count":26},{"year":2012,"cited_by_count":34}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}