{"id":"https://openalex.org/W2016648787","doi":"https://doi.org/10.1093/neuonc/nou174.364","title":"P17.35 * GEINO-10: A PROSPECTIVE OBSERVATIONAL MULTICENTER STUDY OF THE CHARACTERISTICS OF PATIENTS WITH INTRA-AXIAL BRAIN TUMOURS AND THEIR THERAPEUTIC MANAGEMENT IN SPANISH HOSPITALS","display_name":"P17.35 * GEINO-10: A PROSPECTIVE OBSERVATIONAL MULTICENTER STUDY OF THE CHARACTERISTICS OF PATIENTS WITH INTRA-AXIAL BRAIN TUMOURS AND THEIR THERAPEUTIC MANAGEMENT IN SPANISH HOSPITALS","publication_year":2014,"publication_date":"2014-09-01","ids":{"openalex":"https://openalex.org/W2016648787","doi":"https://doi.org/10.1093/neuonc/nou174.364","mag":"2016648787","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4185732"},"language":"en","primary_location":{"id":"doi:10.1093/neuonc/nou174.364","doi":"https://doi.org/10.1093/neuonc/nou174.364","is_oa":false,"landing_page_url":"https://doi.org/10.1093/neuonc/nou174.364","pdf_url":null,"source":{"id":"https://openalex.org/S106908163","display_name":"Neuro-Oncology","issn_l":"1522-8517","issn":["1522-8517","1523-5866"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuro-Oncology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4185732/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032379353","display_name":"Miguel Gil\u2010Gil","orcid":"https://orcid.org/0000-0003-1380-2718","observed_orcids":["https://orcid.org/0000-0003-1380-2718"]},"institutions":[{"id":"https://openalex.org/I4210107147","display_name":"Institut Catal\u00e0 d'Oncologia","ror":"https://ror.org/01j1eb875","country_code":"ES","type":"government","lineage":["https://openalex.org/I4210107147"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"M. J. Gil-Gil","raw_affiliation_strings":["Institut Catala d'Oncologia, \u0139Hospitalet. Barcelona, Spain","1Institut Catala d'Oncologia, \u0139Hospitalet. Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Catala d'Oncologia, \u0139Hospitalet. Barcelona, Spain","institution_ids":["https://openalex.org/I4210107147"]},{"raw_affiliation_string":"1Institut Catala d'Oncologia, \u0139Hospitalet. Barcelona, Spain","institution_ids":["https://openalex.org/I4210107147"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080323920","display_name":"Juan Manuel Sep\u00falveda-S\u00e1nchez","orcid":"https://orcid.org/0000-0003-4338-5804","observed_orcids":["https://orcid.org/0000-0003-4338-5804"]},"institutions":[{"id":"https://openalex.org/I4210101691","display_name":"Hospital Universitario 12 De Octubre","ror":"https://ror.org/00qyh5r35","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210101691","https://openalex.org/I4210139293"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"J. M. Sepulveda","raw_affiliation_strings":["Hospital Universitario 12 de Octubre, Madrid, Spain","2Hospital Universitario 12 de Octubre, Madrid, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Universitario 12 de Octubre, Madrid, Spain","institution_ids":["https://openalex.org/I4210101691"]},{"raw_affiliation_string":"2Hospital Universitario 12 de Octubre, Madrid, Spain","institution_ids":["https://openalex.org/I4210101691"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029623776","display_name":"Jos\u00e9 Mar\u00eda Vi\u00e9itez","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. M. Vieitez","raw_affiliation_strings":["Hospital General de Asturias, Oviedo, Spain","3Hospital General de Asturias, Oviedo, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital General de Asturias, Oviedo, Spain","institution_ids":[]},{"raw_affiliation_string":"3Hospital General de Asturias, Oviedo, Spain","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022488184","display_name":"Ramon De Las Pe\u00f1as Bataller","orcid":"https://orcid.org/0000-0002-2170-4168","observed_orcids":["https://orcid.org/0000-0002-2170-4168"]},"institutions":[{"id":"https://openalex.org/I4210096764","display_name":"Consorcio Hospitalario Provincial de Castell\u00f3n","ror":"https://ror.org/00t7jb983","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210096764"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"R. d. l. Penas","raw_affiliation_strings":["4Hospital Provincial de Castell\u00f3n, Castell\u00f3n de la Plana, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"4Hospital Provincial de Castell\u00f3n, Castell\u00f3n de la Plana, Spain","institution_ids":["https://openalex.org/I4210096764"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038686134","display_name":"Isaura Fern\u00e1ndez P\u00e9rez","orcid":"https://orcid.org/0009-0000-8904-9190","observed_orcids":["https://orcid.org/0009-0000-8904-9190"]},"institutions":[{"id":"https://openalex.org/I2802353815","display_name":"University Hospital Complex Of Vigo","ror":"https://ror.org/01ybfxd46","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I2802353815","https://openalex.org/I4210158352"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"I. Fernandez-Perez","raw_affiliation_strings":["Hospital Universitario, Vigo, Spain","5Hospital Universitario, Vigo, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Universitario, Vigo, Spain","institution_ids":["https://openalex.org/I2802353815"]},{"raw_affiliation_string":"5Hospital Universitario, Vigo, Spain","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014016108","display_name":"Pedro P\u00e9rez\u2010Segura","orcid":"https://orcid.org/0000-0001-5049-7199","observed_orcids":["https://orcid.org/0000-0001-5049-7199"]},"institutions":[{"id":"https://openalex.org/I2961216182","display_name":"Hospital Cl\u00ednico San Carlos","ror":"https://ror.org/04d0ybj29","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I2961216182","https://openalex.org/I4210139293"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"P. Perez-Segura","raw_affiliation_strings":["Hospital Cl\u00ednico Universitario San Carlos, Madrid, Spain","6Hospital Cl\u00ednico Universitario San Carlos, Madrid, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Cl\u00ednico Universitario San Carlos, Madrid, Spain","institution_ids":["https://openalex.org/I2961216182"]},{"raw_affiliation_string":"6Hospital Cl\u00ednico Universitario San Carlos, Madrid, Spain","institution_ids":["https://openalex.org/I2961216182"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036300837","display_name":"P. Fuster","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210152826","display_name":"Hospital Universitario Son Espases","ror":"https://ror.org/05jmd4043","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210152826"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"P. Fuster","raw_affiliation_strings":["Hospital Son Espases, Palma de Mallorca, Spain","7Hospital Son Espases, Palma de Mallorca, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Son Espases, Palma de Mallorca, Spain","institution_ids":["https://openalex.org/I4210152826"]},{"raw_affiliation_string":"7Hospital Son Espases, Palma de Mallorca, Spain","institution_ids":["https://openalex.org/I4210152826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091337335","display_name":"M. Martinez-Garcia","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130874","display_name":"Hospital Del Mar","ror":"https://ror.org/03a8gac78","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210130874"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"M. Martinez-Garcia","raw_affiliation_strings":["Hospital del Mar, Barcelona, Spain","8Hospital del Mar, Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital del Mar, Barcelona, Spain","institution_ids":["https://openalex.org/I4210130874"]},{"raw_affiliation_string":"8Hospital del Mar, Barcelona, Spain","institution_ids":["https://openalex.org/I4210130874"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036498779","display_name":"Teresa Quintanar","orcid":"https://orcid.org/0000-0001-5259-9447","observed_orcids":["https://orcid.org/0000-0001-5259-9447"]},"institutions":[{"id":"https://openalex.org/I4210115956","display_name":"Hospital General Universitario de Elche","ror":"https://ror.org/01jmsem62","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115956"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"T. Quintanar","raw_affiliation_strings":["Hospital Universitario, Elche, Spain","9Hospital Universitario, Elche, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Universitario, Elche, Spain","institution_ids":["https://openalex.org/I4210115956"]},{"raw_affiliation_string":"9Hospital Universitario, Elche, Spain","institution_ids":["https://openalex.org/I4210115956"]}]},{"author_position":"last","author":{"id":null,"display_name":"S. del Barco","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210107147","display_name":"Institut Catal\u00e0 d'Oncologia","ror":"https://ror.org/01j1eb875","country_code":"ES","type":"government","lineage":["https://openalex.org/I4210107147"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"S. del Barco","raw_affiliation_strings":["Institut Catala d'Oncologia, Girona, Spain","10Institut Catala d'Oncologia, Girona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Catala d'Oncologia, Girona, Spain","institution_ids":["https://openalex.org/I4210107147"]},{"raw_affiliation_string":"10Institut Catala d'Oncologia, Girona, Spain","institution_ids":["https://openalex.org/I4210107147"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5132,"currency":"USD","value_usd":5132},"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"16","issue":"suppl 2","first_page":"ii95","last_page":"ii95"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11251","display_name":"Meningioma and schwannoma management","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glioblastoma","display_name":"glioblastoma","score":0.9480000138282776},{"id":"https://openalex.org/keywords/anaplastic-astrocytoma","display_name":"anaplastic astrocytoma","score":0.996999979019165},{"id":"https://openalex.org/keywords/surgical-resection","display_name":"surgical resection","score":0.7110000252723694},{"id":"https://openalex.org/keywords/radiotherapy","display_name":"radiotherapy","score":0.8259999752044678},{"id":"https://openalex.org/keywords/temozolomide","display_name":"temozolomide","score":0.878000020980835},{"id":"https://openalex.org/keywords/bevacizumab","display_name":"bevacizumab","score":0.972000002861023},{"id":"https://openalex.org/keywords/stereotactic-biopsy","display_name":"stereotactic biopsy","score":0.4790000021457672},{"id":"https://openalex.org/keywords/adjuvant-therapy","display_name":"adjuvant therapy","score":0.45100000500679016},{"id":"https://openalex.org/keywords/treatment-patterns","display_name":"treatment patterns","score":0.42500001192092896},{"id":"https://openalex.org/keywords/spanish-hospitals","display_name":"Spanish hospitals","score":0.5419999957084656},{"id":"https://openalex.org/keywords/clinical-characteristics","display_name":"clinical features","score":0.414000004529953},{"id":"https://openalex.org/keywords/patient-reported-outcomes","display_name":"patient-reported outcomes","score":0.3659999966621399},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.6309999823570251},{"id":"https://openalex.org/keywords/cognitive-impairment","display_name":"cognitive impairment","score":0.4099999964237213},{"id":"https://openalex.org/keywords/seizures","display_name":"seizures","score":0.38600000739097595}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8757297992706299},{"id":"https://openalex.org/C2777931997","wikidata":"https://www.wikidata.org/wiki/Q1318384","display_name":"Oligodendroglioma","level":4,"score":0.639089822769165},{"id":"https://openalex.org/C2777389519","wikidata":"https://www.wikidata.org/wiki/Q425088","display_name":"Temozolomide","level":3,"score":0.6122233867645264},{"id":"https://openalex.org/C2777802072","wikidata":"https://www.wikidata.org/wiki/Q413299","display_name":"Bevacizumab","level":3,"score":0.5670286417007446},{"id":"https://openalex.org/C2779083369","wikidata":"https://www.wikidata.org/wiki/Q486092","display_name":"Anaplastic astrocytoma","level":4,"score":0.5405998826026917},{"id":"https://openalex.org/C2779130545","wikidata":"https://www.wikidata.org/wiki/Q233309","display_name":"Brain tumor","level":2,"score":0.4780310094356537},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4711885452270508},{"id":"https://openalex.org/C2778880634","wikidata":"https://www.wikidata.org/wiki/Q177755","display_name":"Astrocytoma","level":3,"score":0.44062650203704834},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.4266164302825928},{"id":"https://openalex.org/C2780789225","wikidata":"https://www.wikidata.org/wiki/Q1333608","display_name":"Medulloblastoma","level":2,"score":0.4193831980228424},{"id":"https://openalex.org/C2778227246","wikidata":"https://www.wikidata.org/wiki/Q1365309","display_name":"Glioma","level":2,"score":0.36048203706741333},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3601314127445221},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3460756242275238},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.34546899795532227},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.20492428541183472},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.1853327453136444},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1093/neuonc/nou174.364","doi":"https://doi.org/10.1093/neuonc/nou174.364","is_oa":false,"landing_page_url":"https://doi.org/10.1093/neuonc/nou174.364","pdf_url":null,"source":{"id":"https://openalex.org/S106908163","display_name":"Neuro-Oncology","issn_l":"1522-8517","issn":["1522-8517","1523-5866"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuro-Oncology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4185732","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4185732/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuro Oncol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:4185732","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4185732/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuro Oncol","raw_type":"Text"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2339652996","https://openalex.org/W6922091987","https://openalex.org/W3205089303","https://openalex.org/W4404236615","https://openalex.org/W2104426418","https://openalex.org/W2439781954","https://openalex.org/W2168500356","https://openalex.org/W4299298376","https://openalex.org/W3116265913","https://openalex.org/W4224231170"],"abstract_inverted_index":{"INTRODUCTION:":[0],"Primitive":[1],"brain":[2,403],"tumours":[3],"(BT)":[4],"represent":[5],"2%":[6,186,337],"of":[7,63,84,132,215,230,243,254,284,324,357,431],"adult":[8],"malignancies.":[9],"BT":[10,65,148,453],"patients":[11,32,66,98,193,216,231,244,288,328,362,400,426,432],"are":[12,33],"treated":[13,34,88,405],"by":[14],"different":[15],"clinical":[16,56,227,391,450],"specialists":[17],"in":[18,35,71,151,154,322,355,409,416,424,452],"Spanish":[19,44],"hospitals.":[20],"This":[21,387,436],"means":[22],"that":[23],"we":[24],"did":[25],"not":[26,384],"know":[27],"with":[28,194,251,401,433],"certainty":[29],"how":[30],"these":[31],"Spain.":[36,72,410],"To":[37],"improve":[38],"this":[39,48],"knowledge":[40],"the":[41,55,191,390,396,414],"Neuro-Oncology":[42],"Investigation":[43],"Group":[45],"(GEINO)":[46],"designed":[47],"prospective":[49],"observational":[50],"multicenter":[51],"study.":[52],"OBJECTIVE:":[53],"Describe":[54],"and":[57,60,91,106,118,187,210,239,258,275,298,338,392,395,443,447],"pathological":[58,393],"characteristics":[59,394],"therapeutic":[61],"management":[62],"intra-axial":[64,86,402],"diagnosed":[67,80],"after":[68,81],"January":[69,82],"2010":[70,83],"PATIENTS":[73],"AND":[74],"METHODS:":[75],"Patients":[76],">18":[77],"years":[78],"old,":[79],"a":[85,226,252,429],"BT,":[87],"or":[89,162,176,196,286],"not,":[90],"gave":[92],"written":[93],"informed":[94],"consent.":[95],"RESULTS:":[96],"397":[97],"from":[99],"22":[100],"hospitals":[101],"were":[102,116,169,180,262],"enrolled":[103],"between":[104],"08/01/2012":[105],"12/03/2013.":[107],"The":[108,420],"median":[109,253],"age":[110],"was":[111,149,268,320,353,374,383,413],"56.9":[112],"(18-83)":[113],"years.":[114],"58%":[115],"male":[117],"42%":[119],"female.":[120],"87%":[121],"had":[122,126,129],"ECOG":[123],"\u22642.":[124],"48.5%":[125],"comorbidity.":[127],"9%":[128,356],"previous":[130],"history":[131],"cancer":[133],"(2%":[134],"BT).":[135],"Symptoms":[136],"at":[137,291,331,365,406],"diagnoses:":[138],"seizures":[139],"30%,":[140],"epilepsy":[141],"25%,":[142],"cognitive":[143],"impairment":[144],"23.5%,":[145],"ataxia":[146],"7.5%.":[147],"located":[150],"frontal":[152],"lobe":[153],"33.5%,":[155],"temporal":[156],"29%,":[157,346],"parietal":[158],"13%,":[159],"posterior":[160],"fosse":[161],"brainstem":[163],"5%.":[164],"By":[165],"histology":[166],"Glioblastoma":[167],"(GBM)":[168],"67%,":[170],"anaplastic":[171],"astrocytoma":[172,183],"(AA)":[173],"12%,":[174,310],"oligodendroglioma":[175],"oligoastrocytoma":[177],"grade":[178],"2-3":[179],"11%,":[181],"low-grade":[182],"6%,":[184],"medulloblastoma":[185],"ependymoma":[188],"1%.":[189],"Of":[190],"313":[192],"GBM":[195,274,285,373,425],"AA":[197,287,382],"98%":[198],"underwent":[199],"surgery":[200],"(SR):":[201],"40%":[202],"complete":[203],"resection,":[204],"41%":[205],"partial,":[206],"11%":[207],"stereotactic":[208],"biopsy":[209],"7%":[211],"open":[212],"biopsy.":[213],"8%":[214,296],"received":[217,232,245,289,329,363],"neoadjuvant":[218],"temozolomide":[219],"(TMZ)":[220],"+":[221,302,344],"/-":[222],"bevacizumab":[223],"(BV)":[224],"into":[225],"trial.":[228],"94%":[229],"radiotherapy":[233],"(RT):":[234],"72%":[235],"focal,":[236],"21%":[237],"whole-brain":[238],"6%":[240],"hemi-brain.":[241],"83%":[242],"adjuvant":[246],"chemotherapy":[247],"(QT):":[248],"99%":[249],"TMZ":[250,305],"5":[255],"cycles":[256],"(1-18)":[257],"1%":[259],"PCV":[260],"(all":[261],"AA).":[263],"Median":[264,368,379],"Progression":[265],"Free":[266],"survival":[267,370],"10.4":[269],"months":[270,277,376],"(95%CI:":[271,278,377],"9-11.8)":[272],"for":[273,280,372,381,448],"31.1":[276],"12.2-49.9)":[279],"AA.":[281],"130/167":[282],"(78%)":[283],"treatment":[290,330,364,397,412,446],"1st":[292],"relapse:":[293,333],"14%":[294],"SR,":[295],"RT":[297,336],"96%":[299],"QT":[300,339],"(CPT11":[301],"BV":[303,307,345,347],"31.5%,":[304],"20%,":[306],"15.5%,":[308],"fotemustine":[309],"dacomitinib":[311],"4%,":[312,335],"lomustine":[313],"3%":[314],"other":[315,350],"10%).":[316],"Radiological":[317],"response":[318],"(RR)":[319],"documented":[321,354],"26%":[323],"cases.":[325,358],"52":[326],"(32.5%)":[327],"2nd":[332],"SR":[334],"100%":[340],"(Fotemustine":[341],"59%,":[342],"CPT11":[343],"alone":[348],"28.5%,":[349],"8%).":[351],"RR":[352],"Only":[359],"15":[360],"(9%)":[361],"3th":[366],"relapse.":[367],"overall":[369],"(OS)":[371],"23.6":[375],"16-31.2.":[378],"OS":[380,423],"reached.":[385],"CONCLUSION:":[386],"study":[388],"reflects":[389,428],"administered":[398],"to":[399,441,444],"tumors":[404],"Cancer":[407],"Services":[408],"First":[411],"standard":[415],"almost":[417],"all":[418],"patients.":[419,454],"exceptionally":[421],"good":[422,434],"probably":[427],"selection":[430],"ECOG.":[435],"information":[437],"can":[438],"be":[439],"useful":[440],"homogenize":[442],"optimize":[445],"future":[449],"trials":[451]},"counts_by_year":[{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2016-06-24T00:00:00"}