{"id":"https://openalex.org/W2016645971","doi":"https://doi.org/10.1371/journal.pone.0009382","title":"A Human Immunodeficiency Virus Screening Algorithm to Address the High Rate of False-Positive Results in Pregnant Women in Japan","display_name":"A Human Immunodeficiency Virus Screening Algorithm to Address the High Rate of False-Positive Results in Pregnant Women in Japan","publication_year":2010,"publication_date":"2010-02-22","ids":{"openalex":"https://openalex.org/W2016645971","doi":"https://doi.org/10.1371/journal.pone.0009382","mag":"2016645971","pmid":"https://pubmed.ncbi.nlm.nih.gov/20186348","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2826425"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pone.0009382","doi":"https://doi.org/10.1371/journal.pone.0009382","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0009382","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0009382&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS ONE","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0009382&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083954247","display_name":"Takako Shima-Sano","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I125602781","display_name":"Tokyo Medical and Dental University","ror":"https://ror.org/051k3eh31","country_code":"JP","type":"education","lineage":["https://openalex.org/I125602781","https://openalex.org/I4400009020"]},{"id":"https://openalex.org/I4210104113","display_name":"Kanagawa Prefectural Institute of Public Health","ror":"https://ror.org/016c9ds94","country_code":"JP","type":"government","lineage":["https://openalex.org/I4210104113"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Takako Shima-Sano","raw_affiliation_strings":["Division of Microbiology, Kanagawa Prefectural Institute of Public Health, Kanagawa, Japan. sano.ipn@pref.kanagawa.jp","Department of Health Care Management and Planning, Graduate School of Medical and Dental Science, Tokyo Medical and Dental University, Tokyo, Japan","Division of Microbiology, Kanagawa Prefectural Institute of Public Health, Kanagawa, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Microbiology, Kanagawa Prefectural Institute of Public Health, Kanagawa, Japan. sano.ipn@pref.kanagawa.jp","institution_ids":["https://openalex.org/I4210104113"]},{"raw_affiliation_string":"Department of Health Care Management and Planning, Graduate School of Medical and Dental Science, Tokyo Medical and Dental University, Tokyo, Japan","institution_ids":["https://openalex.org/I125602781"]},{"raw_affiliation_string":"Division of Microbiology, Kanagawa Prefectural Institute of Public Health, Kanagawa, Japan","institution_ids":["https://openalex.org/I4210104113"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Rika Yamada","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119324","display_name":"Ishikawa Prefectural Central Hospital","ror":"https://ror.org/02cv4ah81","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210119324"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Rika Yamada","raw_affiliation_strings":["Center for Women's and Children's Health, Department of Obstetrics and Gynecology, Ishikawa Prefectural Central Hospital, Ishikawa, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Women's and Children's Health, Department of Obstetrics and Gynecology, Ishikawa Prefectural Central Hospital, Ishikawa, Japan","institution_ids":["https://openalex.org/I4210119324"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080369514","display_name":"Kazuyo Sekita","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kazuyo Sekita","raw_affiliation_strings":["Health Sciences Research Institute, Incorporated, Kanagawa, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Health Sciences Research Institute, Incorporated, Kanagawa, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090899397","display_name":"Raleigh W. Hankins","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Raleigh W. Hankins","raw_affiliation_strings":["Health Sciences Research Institute, Incorporated, Kanagawa, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Health Sciences Research Institute, Incorporated, Kanagawa, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074226470","display_name":"Hiromasa Hori","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hiromasa Hori","raw_affiliation_strings":["Hori Maternity Hospital, Kanagawa, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hori Maternity Hospital, Kanagawa, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080849785","display_name":"Seto Hiroshi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hiroshi Seto","raw_affiliation_strings":["Seto Hospital, Saitama, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Seto Hospital, Saitama, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113477775","display_name":"Koji Sudo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I203951103","display_name":"Keio University","ror":"https://ror.org/02kn6nx58","country_code":"JP","type":"education","lineage":["https://openalex.org/I203951103"]},{"id":"https://openalex.org/I4210104113","display_name":"Kanagawa Prefectural Institute of Public Health","ror":"https://ror.org/016c9ds94","country_code":"JP","type":"government","lineage":["https://openalex.org/I4210104113"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Koji Sudo","raw_affiliation_strings":["Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan","Division of Microbiology, Kanagawa Prefectural Institute of Public Health, Kanagawa, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan","institution_ids":["https://openalex.org/I203951103"]},{"raw_affiliation_string":"Division of Microbiology, Kanagawa Prefectural Institute of Public Health, Kanagawa, Japan","institution_ids":["https://openalex.org/I4210104113"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055321414","display_name":"Makiko Kondo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210104113","display_name":"Kanagawa Prefectural Institute of Public Health","ror":"https://ror.org/016c9ds94","country_code":"JP","type":"government","lineage":["https://openalex.org/I4210104113"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Makiko Kondo","raw_affiliation_strings":["Division of Microbiology, Kanagawa Prefectural Institute of Public Health, Kanagawa, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Microbiology, Kanagawa Prefectural Institute of Public Health, Kanagawa, Japan","institution_ids":["https://openalex.org/I4210104113"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111530087","display_name":"Kazuo Kawahara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I125602781","display_name":"Tokyo Medical and Dental University","ror":"https://ror.org/051k3eh31","country_code":"JP","type":"education","lineage":["https://openalex.org/I125602781","https://openalex.org/I4400009020"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazuo Kawahara","raw_affiliation_strings":["Department of Health Care Management and Planning, Graduate School of Medical and Dental Science, Tokyo Medical and Dental University, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Health Care Management and Planning, Graduate School of Medical and Dental Science, Tokyo Medical and Dental University, Tokyo, Japan","institution_ids":["https://openalex.org/I125602781"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074512092","display_name":"Yuki Tsukahara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210132193","display_name":"National Center For Child Health and Development","ror":"https://ror.org/03fvwxc59","country_code":"JP","type":"government","lineage":["https://openalex.org/I4210132193"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yuki Tsukahara","raw_affiliation_strings":["Division of Obstetrics, National Center for Child Health and Development, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Obstetrics, National Center for Child Health and Development, Tokyo, Japan","institution_ids":["https://openalex.org/I4210132193"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014800098","display_name":"Noriyuki Inaba","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I78274823","display_name":"Dokkyo Medical University","ror":"https://ror.org/05k27ay38","country_code":"JP","type":"education","lineage":["https://openalex.org/I78274823"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Noriyuki Inaba","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Dokkyo Medical University, Tochigi, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Dokkyo Medical University, Tochigi, Japan","institution_ids":["https://openalex.org/I78274823"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101627676","display_name":"Shingo Kato","orcid":"https://orcid.org/0000-0002-8125-1981","observed_orcids":["https://orcid.org/0000-0002-8125-1981"]},"institutions":[{"id":"https://openalex.org/I203951103","display_name":"Keio University","ror":"https://ror.org/02kn6nx58","country_code":"JP","type":"education","lineage":["https://openalex.org/I203951103"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shingo Kato","raw_affiliation_strings":["Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan","institution_ids":["https://openalex.org/I203951103"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110765806","display_name":"Mitsunobu Imai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210104113","display_name":"Kanagawa Prefectural Institute of Public Health","ror":"https://ror.org/016c9ds94","country_code":"JP","type":"government","lineage":["https://openalex.org/I4210104113"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Mitsunobu Imai","raw_affiliation_strings":["Division of Microbiology, Kanagawa Prefectural Institute of Public Health, Kanagawa, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Microbiology, Kanagawa Prefectural Institute of Public Health, Kanagawa, Japan","institution_ids":["https://openalex.org/I4210104113"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5083954247"],"corresponding_institution_ids":["https://openalex.org/I125602781","https://openalex.org/I4210104113"],"apc_list":{"value":2382,"currency":"USD","value_usd":2382},"apc_paid":{"value":2382,"currency":"USD","value_usd":2382},"fwci":1.4853,"has_fulltext":true,"cited_by_count":20,"citation_normalized_percentile":{"value":0.80974026,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"5","issue":"2","first_page":"e9382","last_page":"e9382"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.007600000128149986,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11314","display_name":"Clinical Laboratory Practices and Quality Control","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/3607","display_name":"Medical Laboratory Technology"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hiv-screening","display_name":"HIV screening","score":0.7760000228881836},{"id":"https://openalex.org/keywords/antenatal-hiv-testing","display_name":"antenatal HIV testing","score":0.8840000033378601},{"id":"https://openalex.org/keywords/pregnant-women","display_name":"pregnant women","score":0.890999972820282},{"id":"https://openalex.org/keywords/false-positive-results","display_name":"false positives","score":0.9570000171661377},{"id":"https://openalex.org/keywords/positive-predictive-value","display_name":"positive predictive value","score":0.8669999837875366},{"id":"https://openalex.org/keywords/mother-to-child-transmission","display_name":"mother-to-child transmission","score":0.7710000276565552},{"id":"https://openalex.org/keywords/confirmatory-testing","display_name":"confirmatory testing","score":0.8640000224113464},{"id":"https://openalex.org/keywords/japan","display_name":"Japan","score":0.6740000247955322}],"concepts":[{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.614928662776947},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5293757915496826},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.41103145480155945},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.39652198553085327},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.3841896653175354},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.3472434878349304},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2453957200050354},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.2100786566734314},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0914846658706665}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004797","descriptor_name":"Enzyme-Linked Immunosorbent Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006678","descriptor_name":"HIV","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D006678","descriptor_name":"HIV","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006678","descriptor_name":"HIV","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008403","descriptor_name":"Mass Screening","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011251","descriptor_name":"Pregnancy Complications, Infectious","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D011251","descriptor_name":"Pregnancy Complications, Infectious","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014041","descriptor_name":"Tokyo","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015153","descriptor_name":"Blotting, Western","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015483","descriptor_name":"HIV Antibodies","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D015483","descriptor_name":"HIV Antibodies","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D018445","descriptor_name":"Infectious Disease Transmission, Vertical","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1371/journal.pone.0009382","doi":"https://doi.org/10.1371/journal.pone.0009382","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0009382","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0009382&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS ONE","raw_type":"journal-article"},{"id":"pmid:20186348","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20186348","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PloS one","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2826425","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2826425/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS One","raw_type":"Text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.356.6539","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.356.6539","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/0f/42/PLoS_One_2010_Feb_23_5(2)_e9382.tar.gz","raw_type":"text"},{"id":"pmh:oai:doaj.org/article:a26c6f91c7444629bacbbd7f17369ce9","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/a26c6f91c7444629bacbbd7f17369ce9","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS ONE, Vol 5, Iss 2, p e9382 (2010)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1371/journal.pone.0009382","doi":"https://doi.org/10.1371/journal.pone.0009382","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0009382","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0009382&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS ONE","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2016645971.pdf","grobid_xml":"https://content.openalex.org/works/W2016645971.grobid-xml"},"referenced_works_count":17,"referenced_works":["https://openalex.org/W157884526","https://openalex.org/W1592928656","https://openalex.org/W1825434361","https://openalex.org/W1972982393","https://openalex.org/W1977304931","https://openalex.org/W2002693002","https://openalex.org/W2008806651","https://openalex.org/W2031856716","https://openalex.org/W2097895808","https://openalex.org/W2099183165","https://openalex.org/W2101257289","https://openalex.org/W2127746453","https://openalex.org/W2129863088","https://openalex.org/W2133118862","https://openalex.org/W2159667783","https://openalex.org/W4232368807","https://openalex.org/W4240643377"],"related_works":["https://openalex.org/W1785600638","https://openalex.org/W2403882155","https://openalex.org/W4409332628","https://openalex.org/W4408832622","https://openalex.org/W1968729274","https://openalex.org/W2057261962","https://openalex.org/W7095676813","https://openalex.org/W2145539341","https://openalex.org/W7166136594","https://openalex.org/W2808904356"],"abstract_inverted_index":{"BACKGROUND:":[0],"Prenatal":[1],"human":[2],"immunodeficiency":[3],"virus":[4],"(HIV)":[5],"testing":[6,20,231,266],"is":[7],"essential":[8],"for":[9,35,254,264],"the":[10,46,72,91,144,164,169,175,181,187,194,198,208,218],"prevention":[11],"of":[12,18,50,64,74,95,137,267],"mother-to-child":[13],"transmission.":[14],"However,":[15],"false-positive":[16,75,199],"results":[17],"screening":[19,51,61,76,112,133,189,196,220,227],"are":[21,52],"a":[22,59,110,131,140],"concern":[23],"as":[24,109,130,276],"they":[25],"may":[26],"cause":[27],"unnecessary":[28],"emotional":[29,250],"stress":[30],"to":[31,70,85,100,180,205,214,229,242,249],"pregnant":[32,82,237,268],"women":[33,83,238,269],"waiting":[34,253],"confirmatory":[36,176,244,256],"test":[37,156,257],"results.":[38,77,258],"In":[39],"regions":[40,274],"with":[41,174,186,217],"an":[42],"extremely":[43],"low":[44,54,272],"prevalence,":[45],"positive":[47,116,120,141,162,173,185,209],"predictive":[48,210],"values":[49],"unacceptably":[53],"rate.":[55],"Here,":[56],"we":[57],"propose":[58],"HIV":[60,107,127,230,265],"algorithm":[62,228,260],"consisting":[63],"serial":[65,226],"two":[66,86],"fourth-generation":[67],"enzyme":[68],"immunoassays":[69],"reduce":[71],"number":[73],"METHODOLOGY/PRINCIPAL":[78],"FINDINGS:":[79],"When":[80,118],"6461":[81],"presenting":[84],"maternity":[87,233],"hospitals":[88],"located":[89],"in":[90,232,271],"Tokyo":[92],"metropolitan":[93],"area":[94],"Japan":[96],"from":[97,203,212],"September,":[98],"2004":[99],"January,":[101],"2006":[102],"were":[103,123,147,167],"tested":[104,124],"using":[105,125],"Enzygnost":[106],"Integral":[108],"first":[111],"test,":[113,134,197],"27":[114],"showed":[115,158],"reactions.":[117],"these":[119],"reaction":[121],"samples":[122],"VIDAS":[126],"DUO":[128],"Quick":[129],"second":[132,188,195],"only":[135],"one":[136,160],"them":[138],"had":[139],"reaction,":[142],"and":[143,152,163,207,246],"remaining":[145,165],"26":[146,166],"nonreactive.":[148],"Confirmatory":[149],"Western":[150],"blots":[151],"nucleic":[153],"acid":[154],"amplification":[155],"also":[157],"that":[159],"was":[161,172,178,184,201],"negative;":[168],"subject":[170,182],"who":[171,183],"tests":[177,245],"identical":[179],"test.":[190,221],"Thus,":[191],"by":[192],"adding":[193],"rate":[200],"improved":[202],"0.4%":[204],"0%,":[206],"value":[211],"3.7%":[213],"100%,":[215],"compared":[216],"single":[219],"CONCLUSION:":[222],"By":[223],"applying":[224],"our":[225],"hospitals,":[234],"many":[235],"uninfected":[236],"would":[239,261],"not":[240],"need":[241],"receive":[243],"be":[247,262],"subjected":[248],"turmoil":[251],"while":[252],"their":[255],"This":[259],"suitable":[263],"living":[270],"prevalence":[273],"such":[275],"Japan.":[277]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}