{"id":"https://openalex.org/W2016644055","doi":"https://doi.org/10.1002/app.40903","title":"Synthesis, antimicrobial activity, and release of tetracycline hydrochloride loaded poly(vinyl alcohol)/soybean protein isolate/zirconium dioxide nanofibrous membranes","display_name":"Synthesis, antimicrobial activity, and release of tetracycline hydrochloride loaded poly(vinyl alcohol)/soybean protein isolate/zirconium dioxide nanofibrous membranes","publication_year":2014,"publication_date":"2014-05-13","ids":{"openalex":"https://openalex.org/W2016644055","doi":"https://doi.org/10.1002/app.40903","mag":"2016644055"},"language":"en","primary_location":{"id":"doi:10.1002/app.40903","doi":"https://doi.org/10.1002/app.40903","is_oa":false,"landing_page_url":"https://doi.org/10.1002/app.40903","pdf_url":null,"source":{"id":"https://openalex.org/S200764475","display_name":"Journal of Applied Polymer Science","issn_l":"0021-8995","issn":["0021-8995","1097-4628"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Applied Polymer Science","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100637951","display_name":"Hualin Wang","orcid":"https://orcid.org/0000-0002-2516-6774","observed_orcids":["https://orcid.org/0000-0002-2516-6774"]},"institutions":[{"id":"https://openalex.org/I16365422","display_name":"Hefei University of Technology","ror":"https://ror.org/02czkny70","country_code":"CN","type":"education","lineage":["https://openalex.org/I16365422"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Hualin Wang","raw_affiliation_strings":["Anhui Institute of Agro-Products Intensive Processing Technology, Hefei, Anhui, 230009 People's Republic of China","School of Chemical Technology, Hefei University of Technology, Hefei, Anhui, 230009 People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anhui Institute of Agro-Products Intensive Processing Technology, Hefei, Anhui, 230009 People's Republic of China","institution_ids":[]},{"raw_affiliation_string":"School of Chemical Technology, Hefei University of Technology, Hefei, Anhui, 230009 People's Republic of China","institution_ids":["https://openalex.org/I16365422"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5115602121","display_name":"Yanan Li","orcid":"https://orcid.org/0000-0001-7496-1507","observed_orcids":["https://orcid.org/0000-0001-7496-1507"]},"institutions":[{"id":"https://openalex.org/I16365422","display_name":"Hefei University of Technology","ror":"https://ror.org/02czkny70","country_code":"CN","type":"education","lineage":["https://openalex.org/I16365422"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yanan Li","raw_affiliation_strings":["School of Chemical Technology, Hefei University of Technology, Hefei, Anhui, 230009 People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemical Technology, Hefei University of Technology, Hefei, Anhui, 230009 People's Republic of China","institution_ids":["https://openalex.org/I16365422"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113574740","display_name":"Suwei Jiang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I16365422","display_name":"Hefei University of Technology","ror":"https://ror.org/02czkny70","country_code":"CN","type":"education","lineage":["https://openalex.org/I16365422"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Suwei Jiang","raw_affiliation_strings":["Anhui Institute of Agro\u2010Products Intensive Processing Technology Hefei Anhui 230009 People's Republic of China","School of Biotechnology and Food Engineering Hefei University of Technology Hefei Anhui 230009 People's Republic of China","School of Chemical Technology, Hefei University of Technology, Hefei, Anhui, 230009 People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anhui Institute of Agro\u2010Products Intensive Processing Technology Hefei Anhui 230009 People's Republic of China","institution_ids":[]},{"raw_affiliation_string":"School of Biotechnology and Food Engineering Hefei University of Technology Hefei Anhui 230009 People's Republic of China","institution_ids":["https://openalex.org/I16365422"]},{"raw_affiliation_string":"School of Chemical Technology, Hefei University of Technology, Hefei, Anhui, 230009 People's Republic of China","institution_ids":["https://openalex.org/I16365422"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061010414","display_name":"Peng Zhang","orcid":"https://orcid.org/0000-0003-3902-6876","observed_orcids":["https://orcid.org/0000-0003-3902-6876"]},"institutions":[{"id":"https://openalex.org/I16365422","display_name":"Hefei University of Technology","ror":"https://ror.org/02czkny70","country_code":"CN","type":"education","lineage":["https://openalex.org/I16365422"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Peng Zhang","raw_affiliation_strings":["School of Chemical Technology, Hefei University of Technology, Hefei, Anhui, 230009 People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemical Technology, Hefei University of Technology, Hefei, Anhui, 230009 People's Republic of China","institution_ids":["https://openalex.org/I16365422"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Sun Min","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I16365422","display_name":"Hefei University of Technology","ror":"https://ror.org/02czkny70","country_code":"CN","type":"education","lineage":["https://openalex.org/I16365422"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Sun Min","raw_affiliation_strings":["School of Chemical Technology, Hefei University of Technology, Hefei, Anhui, 230009 People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemical Technology, Hefei University of Technology, Hefei, Anhui, 230009 People's Republic of China","institution_ids":["https://openalex.org/I16365422"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045068854","display_name":"Shaotong Jiang","orcid":"https://orcid.org/0000-0001-8965-3005","observed_orcids":["https://orcid.org/0000-0001-8965-3005"]},"institutions":[{"id":"https://openalex.org/I16365422","display_name":"Hefei University of Technology","ror":"https://ror.org/02czkny70","country_code":"CN","type":"education","lineage":["https://openalex.org/I16365422"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shaotong Jiang","raw_affiliation_strings":["Anhui Institute of Agro-Products Intensive Processing Technology, Hefei, Anhui, 230009 People's Republic of China","School of Biotechnology and Food Engineering, Hefei University of Technology, Hefei, Anhui, 230009 People's Republic of China","School of Chemical Technology Hefei University of Technology Hefei Anhui 230009 People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anhui Institute of Agro-Products Intensive Processing Technology, Hefei, Anhui, 230009 People's Republic of China","institution_ids":[]},{"raw_affiliation_string":"School of Biotechnology and Food Engineering, Hefei University of Technology, Hefei, Anhui, 230009 People's Republic of China","institution_ids":["https://openalex.org/I16365422"]},{"raw_affiliation_string":"School of Chemical Technology Hefei University of Technology Hefei Anhui 230009 People's Republic of China","institution_ids":["https://openalex.org/I16365422"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5100637951"],"corresponding_institution_ids":["https://openalex.org/I16365422"],"apc_list":{"value":4140,"currency":"USD","value_usd":4140},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"131","issue":"20","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10729","display_name":"Electrospun Nanofibers in Biomedical Applications","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10729","display_name":"Electrospun Nanofibers in Biomedical Applications","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11966","display_name":"Silk-based biomaterials and applications","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11511","display_name":"Dyeing and Modifying Textile Fibers","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2507","display_name":"Polymers and Plastics"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tetracycline-hydrochloride","display_name":"tetracycline hydrochloride","score":0.9990000128746033},{"id":"https://openalex.org/keywords/polyvinyl-alcohol","display_name":"polyvinyl alcohol","score":0.9800000190734863},{"id":"https://openalex.org/keywords/soy-protein-isolate","display_name":"soy protein isolate","score":1.0},{"id":"https://openalex.org/keywords/zirconia","display_name":"zirconia","score":0.9440000057220459},{"id":"https://openalex.org/keywords/nanofibrous-membranes","display_name":"nanofibrous membranes","score":0.9779999852180481},{"id":"https://openalex.org/keywords/electrospinning","display_name":"electrospinning","score":0.9409999847412109},{"id":"https://openalex.org/keywords/controlled-drug-release","display_name":"controlled drug release","score":0.9179999828338623},{"id":"https://openalex.org/keywords/antimicrobial-activity","display_name":"antimicrobial activity","score":0.9869999885559082},{"id":"https://openalex.org/keywords/staphylococcus-aureus","display_name":"Staphylococcus aureus","score":0.9980000257492065},{"id":"https://openalex.org/keywords/wound-dressings","display_name":"wound dressings","score":0.859000027179718},{"id":"https://openalex.org/keywords/drug-delivery","display_name":"drug delivery","score":0.7540000081062317},{"id":"https://openalex.org/keywords/hybrid-polymer-networks","display_name":"hybrid polymer networks","score":0.7400000095367432},{"id":"https://openalex.org/keywords/thermal-stability","display_name":"thermal stability","score":0.8420000076293945}],"concepts":[{"id":"https://openalex.org/C2780666587","wikidata":"https://www.wikidata.org/wiki/Q409591","display_name":"Vinyl alcohol","level":3,"score":0.9094688296318054},{"id":"https://openalex.org/C2908999040","wikidata":"https://www.wikidata.org/wiki/Q193045","display_name":"Tetracycline Hydrochloride","level":4,"score":0.8059779405593872},{"id":"https://openalex.org/C144796933","wikidata":"https://www.wikidata.org/wiki/Q1533542","display_name":"Electrospinning","level":3,"score":0.7074378728866577},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.6181615591049194},{"id":"https://openalex.org/C2781216036","wikidata":"https://www.wikidata.org/wiki/Q902494","display_name":"Thermostability","level":3,"score":0.600699245929718},{"id":"https://openalex.org/C2778551929","wikidata":"https://www.wikidata.org/wiki/Q146339","display_name":"Polyvinyl alcohol","level":2,"score":0.5898462533950806},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5736063122749329},{"id":"https://openalex.org/C91129048","wikidata":"https://www.wikidata.org/wiki/Q594196","display_name":"Nanofiber","level":2,"score":0.5409058928489685},{"id":"https://openalex.org/C188027245","wikidata":"https://www.wikidata.org/wiki/Q750446","display_name":"Polymer chemistry","level":1,"score":0.47958341240882874},{"id":"https://openalex.org/C13965031","wikidata":"https://www.wikidata.org/wiki/Q243545","display_name":"Nuclear chemistry","level":1,"score":0.44168877601623535},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.4395967423915863},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.39093464612960815},{"id":"https://openalex.org/C2780923616","wikidata":"https://www.wikidata.org/wiki/Q193045","display_name":"Tetracycline","level":3,"score":0.34581777453422546},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.30515170097351074},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.19615906476974487},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.1807774007320404},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.058609992265701294},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/app.40903","doi":"https://doi.org/10.1002/app.40903","is_oa":false,"landing_page_url":"https://doi.org/10.1002/app.40903","pdf_url":null,"source":{"id":"https://openalex.org/S200764475","display_name":"Journal of Applied Polymer Science","issn_l":"0021-8995","issn":["0021-8995","1097-4628"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Applied Polymer Science","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4851934135","display_name":"\u98df\u54c1\u5305\u88c5\u7eb3\u7c73\u963b\u9694\u6d3b\u6027\u53cc\u91cd\u5185\u6d82\u5c42\u819c\u7684\u590d\u5408\u3001\u963b\u9694\u4e0e\u6297\u83cc\u673a\u5236","funder_award_id":"31371859","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8314487076","display_name":null,"funder_award_id":"31171788","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320328099","display_name":"Hefei University of Technology","ror":"https://ror.org/02czkny70"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W1965111815","https://openalex.org/W1970325797","https://openalex.org/W1970429003","https://openalex.org/W1972705323","https://openalex.org/W1975079349","https://openalex.org/W1981953499","https://openalex.org/W1988223511","https://openalex.org/W1992837547","https://openalex.org/W1995850919","https://openalex.org/W1996929363","https://openalex.org/W1999531296","https://openalex.org/W1999851371","https://openalex.org/W2000303546","https://openalex.org/W2004555716","https://openalex.org/W2006882317","https://openalex.org/W2008960582","https://openalex.org/W2009572646","https://openalex.org/W2009764977","https://openalex.org/W2026569399","https://openalex.org/W2027871058","https://openalex.org/W2029865318","https://openalex.org/W2034212999","https://openalex.org/W2052645559","https://openalex.org/W2053387487","https://openalex.org/W2056236782","https://openalex.org/W2070671315","https://openalex.org/W2098707962","https://openalex.org/W2111887673","https://openalex.org/W2115468162","https://openalex.org/W2155464661","https://openalex.org/W2158363156","https://openalex.org/W2170445914","https://openalex.org/W2322297706","https://openalex.org/W2565074907"],"related_works":["https://openalex.org/W1855160502","https://openalex.org/W1992900505","https://openalex.org/W1994056577","https://openalex.org/W1985805087","https://openalex.org/W2197812468","https://openalex.org/W1999650062","https://openalex.org/W2972281491","https://openalex.org/W4206412192","https://openalex.org/W2978871756","https://openalex.org/W7128377349"],"abstract_inverted_index":{"ABSTRACT":[0],"Tetracycline":[1],"hydrochloride":[2,71],"loaded":[3],"poly(vinyl":[4],"alcohol)/soybean":[5],"protein":[6,23],"isolate/zirconium":[7],"(Tet\u2013PVA/SPI/ZrO2)":[8],"nanofibrous":[9,106,127],"membranes":[10,107,128],"were":[11,39,58,83,129],"fabricated":[12],"via":[13],"an":[14],"electrospinning":[15],"technique.":[16],"The":[17,55,77,104,119],"average":[18],"diameter":[19],"of":[20,66,95,100,121],"the":[21,37,47,63,67,89,93,98,101],"PVA/soybean":[22],"isolate":[24],"(SPI)/ZrO2":[25],"nanofibers":[26,38,57],"used":[27],"as":[28],"drug":[29,69,132],"carriers":[30],"increased":[31],"with":[32],"increasing":[33],"ZrO2":[34,48,81,96],"content,":[35],"and":[36,41,80,92,113,134],"uneven":[40],"tended":[42],"to":[43],"stick":[44],"together":[45],"when":[46,62],"content":[49],"was":[50,72],"above":[51],"15":[52],"wt":[53,75],"%.":[54,76],"Tet\u2013PVA/SPI/ZrO2":[56,105],"similar":[59],"in":[60,88],"morphology":[61],"loading":[64],"dosage":[65],"model":[68],"tetracycline":[70],"below":[73],"6":[74],"PVA,":[78],"SPI,":[79],"units":[82],"linked":[84],"by":[85],"hydrogen":[86],"bonds":[87],"hybrid":[90],"networks,":[91],"addition":[94],"improved":[97],"thermostability":[99],"polymer":[102],"matrix.":[103],"exhibited":[108],"good":[109],"controlled":[110],"drug\u2010release":[111],"properties":[112],"antimicrobial":[114],"activity":[115],"against":[116],"Staphylococcus":[117],"aureus.":[118],"results":[120],"this":[122],"study":[123],"suggest":[124],"that":[125],"those":[126],"suitable":[130],"for":[131],"delivery":[133],"wound":[135],"dressing.":[136],"\u00a9":[137],"2014":[138],"Wiley":[139],"Periodicals,":[140],"Inc.":[141],"J.":[142],"Appl.":[143],"Polym.":[144],"Sci.":[145],"2014,":[146],"131,":[147],"40903.":[148]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2016-06-24T00:00:00"}