{"id":"https://openalex.org/W2016613716","doi":"https://doi.org/10.1139/o77-072","title":"A methodology for the production of carbohydrate-specific antibody","display_name":"A methodology for the production of carbohydrate-specific antibody","publication_year":1977,"publication_date":"1977-05-01","ids":{"openalex":"https://openalex.org/W2016613716","doi":"https://doi.org/10.1139/o77-072","mag":"2016613716","pmid":"https://pubmed.ncbi.nlm.nih.gov/69478"},"language":"en","primary_location":{"id":"doi:10.1139/o77-072","doi":"https://doi.org/10.1139/o77-072","is_oa":false,"landing_page_url":"https://doi.org/10.1139/o77-072","pdf_url":null,"source":{"id":"https://openalex.org/S4210188051","display_name":"Canadian Journal of Biochemistry","issn_l":"0008-4018","issn":["0008-4018"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310312929","host_organization_name":"Canadian Science Publishing","host_organization_lineage":["https://openalex.org/P4310312929"],"host_organization_lineage_names":["Canadian Science Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Canadian Journal of Biochemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111758442","display_name":"R. U. Lemieux","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R. U. Lemieux","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"D. A. Baker","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D. A. Baker","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5073005007","display_name":"David R. Bundle","orcid":"https://orcid.org/0000-0003-0497-3961","observed_orcids":["https://orcid.org/0000-0003-0497-3961"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D. R. Bundle","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.4764,"has_fulltext":false,"cited_by_count":71,"citation_normalized_percentile":{"value":0.85977171,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"55","issue":"5","first_page":"507","last_page":"512"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10835","display_name":"Carbohydrate Chemistry and Synthesis","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10835","display_name":"Carbohydrate Chemistry and Synthesis","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.0027000000700354576,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glycoside-synthesis","display_name":"glycoside synthesis","score":0.7799999713897705},{"id":"https://openalex.org/keywords/artificial-antigen","display_name":"artificial antigen","score":0.8169999718666077},{"id":"https://openalex.org/keywords/anti-hapten-antibodies","display_name":"hapten-specific antibodies","score":0.7689999938011169},{"id":"https://openalex.org/keywords/immunodominant-epitopes","display_name":"immunodominant epitopes","score":0.7820000052452087},{"id":"https://openalex.org/keywords/vaccination-schedule","display_name":"vaccination schedule","score":0.5649999976158142},{"id":"https://openalex.org/keywords/homologous-antibodies","display_name":"homologous antibodies","score":0.722000002861023}],"concepts":[{"id":"https://openalex.org/C29144244","wikidata":"https://www.wikidata.org/wiki/Q506441","display_name":"Hapten","level":3,"score":0.834243655204773},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.69524085521698},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.6199385523796082},{"id":"https://openalex.org/C2778977261","wikidata":"https://www.wikidata.org/wiki/Q11358","display_name":"Carbohydrate","level":2,"score":0.5780307054519653},{"id":"https://openalex.org/C194671627","wikidata":"https://www.wikidata.org/wiki/Q192639","display_name":"Glycoside","level":2,"score":0.5191428065299988},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4006504416465759},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3810337781906128},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3240247964859009},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.323365718126297},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.11610540747642517}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000917","descriptor_name":"Antibody Formation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000939","descriptor_name":"Epitopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002241","descriptor_name":"Carbohydrates","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D005779","descriptor_name":"Immunodiffusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006027","descriptor_name":"Glycosides","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006241","descriptor_name":"Haptens","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011233","descriptor_name":"Precipitin Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D012710","descriptor_name":"Serum Albumin, Bovine","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1139/o77-072","doi":"https://doi.org/10.1139/o77-072","is_oa":false,"landing_page_url":"https://doi.org/10.1139/o77-072","pdf_url":null,"source":{"id":"https://openalex.org/S4210188051","display_name":"Canadian Journal of Biochemistry","issn_l":"0008-4018","issn":["0008-4018"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310312929","host_organization_name":"Canadian Science Publishing","host_organization_lineage":["https://openalex.org/P4310312929"],"host_organization_lineage_names":["Canadian Science Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Canadian Journal of Biochemistry","raw_type":"journal-article"},{"id":"pmid:69478","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/69478","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Canadian journal of biochemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":1,"referenced_works":["https://openalex.org/W2318443994"],"related_works":["https://openalex.org/W2025275322","https://openalex.org/W1851677292","https://openalex.org/W2005961413","https://openalex.org/W1982840962","https://openalex.org/W2025121511","https://openalex.org/W2123217919","https://openalex.org/W2182751569","https://openalex.org/W2025038866","https://openalex.org/W1965770896","https://openalex.org/W2949131187"],"abstract_inverted_index":{"8-Methoxycarbonyloctyl":[0],"glycosides":[1],"are":[2,31,42],"recommended":[3],"as":[4],"precursors":[5],"for":[6],"the":[7,35,67],"preparation":[8,20],"of":[9,24,28,38,62],"artificial":[10],"antigens":[11,30,65],"that":[12,41],"possess":[13],"strongly":[14],"immunodominant":[15],"carbohydrate":[16],"antigenic":[17],"determinants.":[18],"The":[19,49],"and":[21,66],"immunochemical":[22],"properties":[23],"a":[25,59],"selected":[26],"number":[27],"these":[29],"reported":[32],"to":[33,56],"demonstrate":[34],"high":[36],"levels":[37],"hapten-specific":[39],"antibodies":[40],"normally":[43],"achieved":[44],"using":[45],"standard":[46],"immunization":[47],"schedules.":[48],"method,":[50],"based":[51],"on":[52],"glycoside":[53],"synthesis,":[54],"promises":[55],"make":[57],"available":[58],"wide":[60],"spectrum":[61],"well":[63],"defined":[64],"homologous":[68],"antibodies.":[69]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}