{"id":"https://openalex.org/W2016605650","doi":"https://doi.org/10.1089/ten.tec.2009.0392","title":"Preparation of Cardiac Extracellular Matrix from an Intact Porcine Heart","display_name":"Preparation of Cardiac Extracellular Matrix from an Intact Porcine Heart","publication_year":2009,"publication_date":"2009-08-25","ids":{"openalex":"https://openalex.org/W2016605650","doi":"https://doi.org/10.1089/ten.tec.2009.0392","mag":"2016605650","pmid":"https://pubmed.ncbi.nlm.nih.gov/19702513"},"language":"en","primary_location":{"id":"doi:10.1089/ten.tec.2009.0392","doi":"https://doi.org/10.1089/ten.tec.2009.0392","is_oa":false,"landing_page_url":"https://doi.org/10.1089/ten.tec.2009.0392","pdf_url":null,"source":{"id":"https://openalex.org/S190192123","display_name":"Tissue Engineering Part C Methods","issn_l":"1937-3384","issn":["1937-3384","1937-3392"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tissue Engineering Part C: Methods","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2945869","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"John M. Wainwright","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I4210155891","display_name":"McGowan Institute for Regenerative Medicine","ror":"https://ror.org/04js6xx21","country_code":"US","type":"facility","lineage":["https://openalex.org/I170201317","https://openalex.org/I4210098814","https://openalex.org/I4210134769","https://openalex.org/I4210155891"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John M. Wainwright","raw_affiliation_strings":["University of Pittsburgh","Department of Surgery, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pittsburgh","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Department of Surgery, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania","institution_ids":["https://openalex.org/I170201317","https://openalex.org/I4210155891"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025754987","display_name":"Caitlin A. Czajka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I4210155891","display_name":"McGowan Institute for Regenerative Medicine","ror":"https://ror.org/04js6xx21","country_code":"US","type":"facility","lineage":["https://openalex.org/I170201317","https://openalex.org/I4210098814","https://openalex.org/I4210134769","https://openalex.org/I4210155891"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Caitlin A. Czajka","raw_affiliation_strings":["University of Pittsburgh","Department of Surgery, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pittsburgh","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Department of Surgery, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania","institution_ids":["https://openalex.org/I170201317","https://openalex.org/I4210155891"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043402983","display_name":"Urvi B. Patel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I4210155891","display_name":"McGowan Institute for Regenerative Medicine","ror":"https://ror.org/04js6xx21","country_code":"US","type":"facility","lineage":["https://openalex.org/I170201317","https://openalex.org/I4210098814","https://openalex.org/I4210134769","https://openalex.org/I4210155891"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Urvi B. Patel","raw_affiliation_strings":["University of Pittsburgh","Department of Surgery, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pittsburgh","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Department of Surgery, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania","institution_ids":["https://openalex.org/I170201317","https://openalex.org/I4210155891"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019847998","display_name":"Donald O. Freytes","orcid":"https://orcid.org/0000-0003-4636-5809","observed_orcids":["https://orcid.org/0000-0003-4636-5809"]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Donald O. Freytes","raw_affiliation_strings":["Columbia University","Department of Biomedical Engineering, Columbia University, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Columbia University","institution_ids":["https://openalex.org/I78577930"]},{"raw_affiliation_string":"Department of Biomedical Engineering, Columbia University, New York, New York","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079296516","display_name":"Kimimasa Tobita","orcid":"https://orcid.org/0000-0001-5435-8436","observed_orcids":["https://orcid.org/0000-0001-5435-8436"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I4210130600","display_name":"Children's Hospital of Pittsburgh","ror":"https://ror.org/03763ep67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"id":"https://openalex.org/I4210134769","display_name":"University of Pittsburgh Medical Center","ror":"https://ror.org/04ehecz88","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210134769"]},{"id":"https://openalex.org/I4210155891","display_name":"McGowan Institute for Regenerative Medicine","ror":"https://ror.org/04js6xx21","country_code":"US","type":"facility","lineage":["https://openalex.org/I170201317","https://openalex.org/I4210098814","https://openalex.org/I4210134769","https://openalex.org/I4210155891"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kimimasa Tobita","raw_affiliation_strings":["University of Pittsburgh","University of Pittsburgh Medical Center","Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania","Department of Surgery, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pittsburgh","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"University of Pittsburgh Medical Center","institution_ids":["https://openalex.org/I4210134769"]},{"raw_affiliation_string":"Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania","institution_ids":["https://openalex.org/I170201317","https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"raw_affiliation_string":"Department of Surgery, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania","institution_ids":["https://openalex.org/I170201317","https://openalex.org/I4210155891"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084755741","display_name":"Thomas W. Gilbert","orcid":"https://orcid.org/0000-0002-9119-7149","observed_orcids":["https://orcid.org/0000-0002-9119-7149"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I4210130600","display_name":"Children's Hospital of Pittsburgh","ror":"https://ror.org/03763ep67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"id":"https://openalex.org/I4210134769","display_name":"University of Pittsburgh Medical Center","ror":"https://ror.org/04ehecz88","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210134769"]},{"id":"https://openalex.org/I4210155891","display_name":"McGowan Institute for Regenerative Medicine","ror":"https://ror.org/04js6xx21","country_code":"US","type":"facility","lineage":["https://openalex.org/I170201317","https://openalex.org/I4210098814","https://openalex.org/I4210134769","https://openalex.org/I4210155891"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas W. Gilbert","raw_affiliation_strings":["University of Pittsburgh","University of Pittsburgh Medical Center","Department of Cardiothoracic Surgery, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania","Department of Surgery, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pittsburgh","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"University of Pittsburgh Medical Center","institution_ids":["https://openalex.org/I4210134769"]},{"raw_affiliation_string":"Department of Cardiothoracic Surgery, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania","institution_ids":["https://openalex.org/I170201317","https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"raw_affiliation_string":"Department of Surgery, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania","institution_ids":["https://openalex.org/I170201317","https://openalex.org/I4210155891"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5073097748","display_name":"Stephen F. Badylak","orcid":"https://orcid.org/0000-0003-3555-0689","observed_orcids":["https://orcid.org/0000-0003-3555-0689"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I4210155891","display_name":"McGowan Institute for Regenerative Medicine","ror":"https://ror.org/04js6xx21","country_code":"US","type":"facility","lineage":["https://openalex.org/I170201317","https://openalex.org/I4210098814","https://openalex.org/I4210134769","https://openalex.org/I4210155891"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Stephen F. Badylak","raw_affiliation_strings":["University of Pittsburgh","Department of Surgery, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pittsburgh","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Department of Surgery, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania","institution_ids":["https://openalex.org/I170201317","https://openalex.org/I4210155891"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5073097748"],"corresponding_institution_ids":["https://openalex.org/I170201317","https://openalex.org/I4210155891"],"apc_list":null,"apc_paid":null,"fwci":17.5128,"has_fulltext":false,"cited_by_count":326,"citation_normalized_percentile":{"value":0.99499517,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"16","issue":"3","first_page":"525","last_page":"532"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10675","display_name":"Mechanical Circulatory Support Devices","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cardiac-extracellular-matrix","display_name":"cardiac extracellular matrix","score":0.9750000238418579},{"id":"https://openalex.org/keywords/decellularization","display_name":"decellularization","score":0.9470000267028809},{"id":"https://openalex.org/keywords/porcine-heart","display_name":"porcine heart","score":0.925000011920929},{"id":"https://openalex.org/keywords/3d-scaffolds","display_name":"3D scaffolds","score":0.8140000104904175},{"id":"https://openalex.org/keywords/collagen","display_name":"collagen","score":0.4909999966621399},{"id":"https://openalex.org/keywords/elastin","display_name":"elastin","score":0.9980000257492065},{"id":"https://openalex.org/keywords/glycosaminoglycans","display_name":"glycosaminoglycans","score":0.9990000128746033},{"id":"https://openalex.org/keywords/sarcomere-organization","display_name":"sarcomere organization","score":0.8169999718666077},{"id":"https://openalex.org/keywords/mechanical-integrity","display_name":"mechanical integrity","score":0.5360000133514404}],"concepts":[{"id":"https://openalex.org/C190672674","wikidata":"https://www.wikidata.org/wiki/Q3866591","display_name":"Decellularization","level":3,"score":0.9869446158409119},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.815437376499176},{"id":"https://openalex.org/C2779869378","wikidata":"https://www.wikidata.org/wiki/Q409747","display_name":"Elastin","level":2,"score":0.711195707321167},{"id":"https://openalex.org/C49892992","wikidata":"https://www.wikidata.org/wiki/Q1540285","display_name":"Tissue engineering","level":2,"score":0.6771294474601746},{"id":"https://openalex.org/C89429830","wikidata":"https://www.wikidata.org/wiki/Q735710","display_name":"Scaffold","level":2,"score":0.666046142578125},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.6256440877914429},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.537307620048523},{"id":"https://openalex.org/C153074725","wikidata":"https://www.wikidata.org/wiki/Q407553","display_name":"Glycosaminoglycan","level":2,"score":0.5247438549995422},{"id":"https://openalex.org/C146957229","wikidata":"https://www.wikidata.org/wiki/Q1266915","display_name":"Perfusion","level":2,"score":0.505214273929596},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4945649802684784},{"id":"https://openalex.org/C10854531","wikidata":"https://www.wikidata.org/wiki/Q1061415","display_name":"Regenerative medicine","level":3,"score":0.49155816435813904},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.34044814109802246},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.311407208442688},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.22145012021064758},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.21769770979881287},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.20474937558174133},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.15576988458633423},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.15318337082862854}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005109","descriptor_name":"Extracellular Matrix","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005109","descriptor_name":"Extracellular Matrix","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005109","descriptor_name":"Extracellular Matrix","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005109","descriptor_name":"Extracellular Matrix","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008855","descriptor_name":"Microscopy, Electron, Scanning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008855","descriptor_name":"Microscopy, Electron, Scanning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008855","descriptor_name":"Microscopy, Electron, Scanning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008855","descriptor_name":"Microscopy, Electron, Scanning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1089/ten.tec.2009.0392","doi":"https://doi.org/10.1089/ten.tec.2009.0392","is_oa":false,"landing_page_url":"https://doi.org/10.1089/ten.tec.2009.0392","pdf_url":null,"source":{"id":"https://openalex.org/S190192123","display_name":"Tissue Engineering Part C Methods","issn_l":"1937-3384","issn":["1937-3384","1937-3392"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tissue Engineering Part C: Methods","raw_type":"journal-article"},{"id":"pmid:19702513","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19702513","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tissue engineering. Part C, Methods","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2945869","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2945869","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Tissue Eng Part C Methods","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2945869","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2945869","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Tissue Eng Part C Methods","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.46810001134872437}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1039939978","display_name":null,"funder_award_id":"#T32-HL076124","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G810331824","display_name":null,"funder_award_id":"T32-HL76124","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G9000874503","display_name":"Cardiovascular Bioengineering Training Program","funder_award_id":"5t32hl076124-18","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":38,"referenced_works":["https://openalex.org/W1875588079","https://openalex.org/W1927971138","https://openalex.org/W1966301990","https://openalex.org/W1969390542","https://openalex.org/W1971189453","https://openalex.org/W1983707837","https://openalex.org/W1987350026","https://openalex.org/W1987602789","https://openalex.org/W1994232607","https://openalex.org/W1995373597","https://openalex.org/W1997547509","https://openalex.org/W2009485059","https://openalex.org/W2019265617","https://openalex.org/W2024894752","https://openalex.org/W2032549615","https://openalex.org/W2040961254","https://openalex.org/W2048920207","https://openalex.org/W2049920231","https://openalex.org/W2067335193","https://openalex.org/W2070431772","https://openalex.org/W2073822758","https://openalex.org/W2074529345","https://openalex.org/W2092020338","https://openalex.org/W2101134052","https://openalex.org/W2101228997","https://openalex.org/W2111296154","https://openalex.org/W2116397695","https://openalex.org/W2118176349","https://openalex.org/W2128603437","https://openalex.org/W2130201056","https://openalex.org/W2131658622","https://openalex.org/W2134506355","https://openalex.org/W2138989174","https://openalex.org/W2150538563","https://openalex.org/W2151838922","https://openalex.org/W2159488658","https://openalex.org/W2165617122","https://openalex.org/W4230240787"],"related_works":["https://openalex.org/W2996628384","https://openalex.org/W2551766506","https://openalex.org/W2592442139","https://openalex.org/W2155537879","https://openalex.org/W2382137987","https://openalex.org/W3159691988","https://openalex.org/W2620876660","https://openalex.org/W2407982840","https://openalex.org/W2085292663","https://openalex.org/W3011098744"],"abstract_inverted_index":{"Whole":[0],"organ":[1],"engineering":[2,125],"would":[3,25],"benefit":[4],"from":[5,10,40],"a":[6,23,123],"three-dimensional":[7],"scaffold":[8,24],"produced":[9],"intact":[11,41,51,118],"organ-specific":[12],"extracellular":[13],"matrix":[14],"(ECM).":[15],"The":[16,34,92,117],"microenvironment":[17],"and":[18,31,77,82,99,101,135],"architecture":[19],"provided":[20],"by":[21],"such":[22,38],"likely":[26],"support":[27],"site-appropriate":[28],"cell":[29],"differentiation":[30],"spatial":[32],"organization.":[33],"methods":[35],"to":[36,87],"produce":[37],"scaffolds":[39],"organs":[42],"require":[43],"customized":[44],"decellularization":[45],"protocols.":[46],"In":[47],"the":[48,107],"present":[49],"study,":[50],"adult":[52],"porcine":[53,120],"hearts":[54],"were":[55],"successfully":[56],"decellularized":[57,119],"in":[58,115],"less":[59],"than":[60],"10":[61],"h":[62],"using":[63],"pulsatile":[64],"retrograde":[65],"aortic":[66],"perfusion.":[67],"Serial":[68],"perfusion":[69],"of":[70,109],"an":[71],"enzymatic,":[72],"nonionic":[73],"detergent,":[74,76],"ionic":[75],"acid":[78],"solution":[79],"with":[80],"hypotonic":[81],"hypertonic":[83],"rinses":[84],"was":[85],"used":[86],"systematically":[88],"remove":[89],"cellular":[90],"content.":[91],"resultant":[93],"cardiac":[94],"ECM":[95,105],"retained":[96],"collagen,":[97],"elastin,":[98],"glycosaminoglycans,":[100],"mechanical":[102],"integrity.":[103],"Cardiac":[104],"supported":[106],"formation":[108],"organized":[110],"chicken":[111],"cardiomyocyte":[112],"sarcomere":[113],"structure":[114],"vitro.":[116],"heart":[121],"provides":[122],"tissue":[124],"template":[126],"that":[127],"may":[128],"be":[129],"beneficial":[130],"for":[131],"future":[132],"preclinical":[133],"studies":[134],"eventual":[136],"clinical":[137],"applications.":[138]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":13},{"year":2023,"cited_by_count":13},{"year":2022,"cited_by_count":11},{"year":2021,"cited_by_count":22},{"year":2020,"cited_by_count":13},{"year":2019,"cited_by_count":22},{"year":2018,"cited_by_count":20},{"year":2017,"cited_by_count":21},{"year":2016,"cited_by_count":21},{"year":2015,"cited_by_count":35},{"year":2014,"cited_by_count":31},{"year":2013,"cited_by_count":33},{"year":2012,"cited_by_count":29}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}