{"id":"https://openalex.org/W2016602933","doi":"https://doi.org/10.1097/00006982-199414030-00013","title":"ACUTE RETINAL NECROSIS SYNDROME ASSOCIATED WITH HERPES SIMPLEX KERATITIS","display_name":"ACUTE RETINAL NECROSIS SYNDROME ASSOCIATED WITH HERPES SIMPLEX KERATITIS","publication_year":1994,"publication_date":"1994-01-01","ids":{"openalex":"https://openalex.org/W2016602933","doi":"https://doi.org/10.1097/00006982-199414030-00013","mag":"2016602933","pmid":"https://pubmed.ncbi.nlm.nih.gov/7973122"},"language":"en","primary_location":{"id":"doi:10.1097/00006982-199414030-00013","doi":"https://doi.org/10.1097/00006982-199414030-00013","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00006982-199414030-00013","pdf_url":null,"source":{"id":"https://openalex.org/S19572933","display_name":"Retina","issn_l":"0275-004X","issn":["0275-004X","1539-2864"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Retina","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077016670","display_name":"Kazushige Sado","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I34077901","display_name":"Juntendo University","ror":"https://ror.org/01692sz90","country_code":"JP","type":"education","lineage":["https://openalex.org/I34077901"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"KAZUSHIGE SADO","raw_affiliation_strings":["Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan","From the Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan","institution_ids":["https://openalex.org/I34077901"]},{"raw_affiliation_string":"From the Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan","institution_ids":["https://openalex.org/I34077901"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103101973","display_name":"Tairo Kimura","orcid":"https://orcid.org/0000-0003-2232-1828","observed_orcids":["https://orcid.org/0000-0003-2232-1828"]},"institutions":[{"id":"https://openalex.org/I34077901","display_name":"Juntendo University","ror":"https://ror.org/01692sz90","country_code":"JP","type":"education","lineage":["https://openalex.org/I34077901"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"TAIRO KIMURA","raw_affiliation_strings":["the Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan","From the Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan","institution_ids":["https://openalex.org/I34077901"]},{"raw_affiliation_string":"From the Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan","institution_ids":["https://openalex.org/I34077901"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055435217","display_name":"Yoshihiro Hotta","orcid":"https://orcid.org/0000-0003-4052-5066","observed_orcids":["https://orcid.org/0000-0003-4052-5066","https://orcid.org/0009-0008-0093-7772"]},"institutions":[{"id":"https://openalex.org/I34077901","display_name":"Juntendo University","ror":"https://ror.org/01692sz90","country_code":"JP","type":"education","lineage":["https://openalex.org/I34077901"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"YOSHIHIRO HOTTA","raw_affiliation_strings":["the Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan","From the Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan","institution_ids":["https://openalex.org/I34077901"]},{"raw_affiliation_string":"From the Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan","institution_ids":["https://openalex.org/I34077901"]}]},{"author_position":"middle","author":{"id":null,"display_name":"HITOSHI SAKUMA","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I34077901","display_name":"Juntendo University","ror":"https://ror.org/01692sz90","country_code":"JP","type":"education","lineage":["https://openalex.org/I34077901"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"HITOSHI SAKUMA","raw_affiliation_strings":["the Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan","From the Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan","institution_ids":["https://openalex.org/I34077901"]},{"raw_affiliation_string":"From the Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan","institution_ids":["https://openalex.org/I34077901"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109081586","display_name":"Mutsuko Hayakawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I34077901","display_name":"Juntendo University","ror":"https://ror.org/01692sz90","country_code":"JP","type":"education","lineage":["https://openalex.org/I34077901"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"MUTSUKO HAYAKAWA","raw_affiliation_strings":["the Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan","From the Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan","institution_ids":["https://openalex.org/I34077901"]},{"raw_affiliation_string":"From the Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan","institution_ids":["https://openalex.org/I34077901"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100892415","display_name":"Kazuo Kato","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I34077901","display_name":"Juntendo University","ror":"https://ror.org/01692sz90","country_code":"JP","type":"education","lineage":["https://openalex.org/I34077901"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"KAZUO KATO","raw_affiliation_strings":["the Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan","From the Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan","institution_ids":["https://openalex.org/I34077901"]},{"raw_affiliation_string":"From the Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan","institution_ids":["https://openalex.org/I34077901"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113866482","display_name":"Atsushi Kanai","orcid":"https://orcid.org/0009-0007-1357-2381","observed_orcids":["https://orcid.org/0009-0007-1357-2381"]},"institutions":[{"id":"https://openalex.org/I34077901","display_name":"Juntendo University","ror":"https://ror.org/01692sz90","country_code":"JP","type":"education","lineage":["https://openalex.org/I34077901"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"ATSUSHI KANAI","raw_affiliation_strings":["the Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan","From the Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan","institution_ids":["https://openalex.org/I34077901"]},{"raw_affiliation_string":"From the Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan","institution_ids":["https://openalex.org/I34077901"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I34077901"],"apc_list":null,"apc_paid":null,"fwci":0.6793,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.68967254,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"14","issue":"3","first_page":"260","last_page":"263"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10625","display_name":"Herpesvirus Infections and Treatments","score":0.42800000309944153,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10625","display_name":"Herpesvirus Infections and Treatments","score":0.42800000309944153,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11194","display_name":"Ocular Diseases and Beh\u00e7et\u2019s Syndrome","score":0.3637999892234802,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11826","display_name":"Ocular Infections and Treatments","score":0.17350000143051147,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/herpes-simplex-keratitis","display_name":"herpes simplex keratitis","score":0.9559999704360962},{"id":"https://openalex.org/keywords/herpes-simplex-virus-type-1","display_name":"herpes simplex virus type 1","score":0.9819999933242798},{"id":"https://openalex.org/keywords/retinal-vasculitis","display_name":"retinal vasculitis","score":0.9929999709129333},{"id":"https://openalex.org/keywords/vitreitis","display_name":"vitritis","score":0.9079999923706055},{"id":"https://openalex.org/keywords/iritis","display_name":"iritis","score":0.9789999723434448},{"id":"https://openalex.org/keywords/tolosa-hunt-syndrome","display_name":"Tolosa-Hunt syndrome","score":0.968999981880188},{"id":"https://openalex.org/keywords/impression-cytology","display_name":"imprint cytology","score":0.8149999976158142},{"id":"https://openalex.org/keywords/aqueous-humor","display_name":"aqueous humor","score":0.7730000019073486},{"id":"https://openalex.org/keywords/corneal-ulcer","display_name":"corneal ulcer","score":0.656000018119812}],"concepts":[{"id":"https://openalex.org/C2777168383","wikidata":"https://www.wikidata.org/wiki/Q4677951","display_name":"Acute retinal necrosis","level":5,"score":0.917618989944458},{"id":"https://openalex.org/C2781196997","wikidata":"https://www.wikidata.org/wiki/Q655331","display_name":"Herpes simplex virus","level":3,"score":0.7174557447433472},{"id":"https://openalex.org/C2778560704","wikidata":"https://www.wikidata.org/wiki/Q757838","display_name":"Keratitis","level":2,"score":0.7077111601829529},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6931097507476807},{"id":"https://openalex.org/C2777016524","wikidata":"https://www.wikidata.org/wiki/Q630552","display_name":"Retinitis","level":4,"score":0.6381998062133789},{"id":"https://openalex.org/C2778328719","wikidata":"https://www.wikidata.org/wiki/Q7316771","display_name":"Retinal vasculitis","level":4,"score":0.5242533683776855},{"id":"https://openalex.org/C2776159415","wikidata":"https://www.wikidata.org/wiki/Q6868","display_name":"Varicella zoster virus","level":3,"score":0.4567088484764099},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.4227236211299896},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.406957745552063},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.3681272864341736},{"id":"https://openalex.org/C2776015282","wikidata":"https://www.wikidata.org/wiki/Q644318","display_name":"Vasculitis","level":3,"score":0.3401092290878296},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.30296799540519714},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.24260830879211426},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.07733076810836792},{"id":"https://openalex.org/C2779820661","wikidata":"https://www.wikidata.org/wiki/Q6929","display_name":"Human cytomegalovirus","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000914","descriptor_name":"Antibodies, Viral","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D004279","descriptor_name":"DNA, Viral","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D005158","descriptor_name":"Facial Paralysis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D005158","descriptor_name":"Facial Paralysis","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009886","descriptor_name":"Ophthalmoplegia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D009886","descriptor_name":"Ophthalmoplegia","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D015882","descriptor_name":"Retinal Necrosis Syndrome, Acute","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D015882","descriptor_name":"Retinal Necrosis Syndrome, Acute","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D016849","descriptor_name":"Keratitis, Herpetic","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D016849","descriptor_name":"Keratitis, Herpetic","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D018259","descriptor_name":"Herpesvirus 1, Human","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018259","descriptor_name":"Herpesvirus 1, Human","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1097/00006982-199414030-00013","doi":"https://doi.org/10.1097/00006982-199414030-00013","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00006982-199414030-00013","pdf_url":null,"source":{"id":"https://openalex.org/S19572933","display_name":"Retina","issn_l":"0275-004X","issn":["0275-004X","1539-2864"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Retina","raw_type":"journal-article"},{"id":"pmid:7973122","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7973122","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Retina (Philadelphia, Pa.)","raw_type":"Case Reports"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2038750036","https://openalex.org/W1989344761","https://openalex.org/W2272920704","https://openalex.org/W2970700996","https://openalex.org/W2080683352","https://openalex.org/W2091335961","https://openalex.org/W2516214859","https://openalex.org/W2031656332","https://openalex.org/W2726810474","https://openalex.org/W3189666262"],"abstract_inverted_index":{"BACKGROUND:":[0],"Although":[1],"acute":[2],"retinal":[3,44],"necrosis":[4],"(ARN)":[5],"syndrome":[6,20,28,52,131],"is":[7,21,33],"caused":[8],"by":[9,89],"a":[10],"herpes":[11,30,139],"group":[12],"virus,":[13],"association":[14],"of":[15,25,71,84],"herpetic":[16,64],"keratitis":[17,32,140],"with":[18,29,50,79,97,138],"ARN":[19,27,51,130],"uncommon.":[22],"A":[23,36],"case":[24,127],"unilateral":[26,40],"simplex":[31,99],"discussed.":[34],"METHODS:":[35],"40-year-old":[37],"man":[38],"developed":[39,77],"keratitis,":[41],"necrotic":[42],"retinitis,":[43],"vasculitis,":[45],"vitritis,":[46],"and":[47,62,83,110],"iritis":[48],"consistent":[49],"1":[53,102],"month":[54],"after":[55],"treatment":[56],"for":[57],"ipsilateral":[58],"facial":[59],"nerve":[60],"palsy":[61],"auricular":[63],"vesicles":[65],"(Tolosa-Hunt":[66],"syndrome).":[67],"Impression":[68],"cytologic":[69],"examination":[70],"the":[72,80,85,115,122],"corneal":[73],"epithelial":[74],"ulcer":[75],"that":[76,95,129],"concurrent":[78],"intraocular":[81],"findings":[82],"aqueous":[86,123],"humor":[87],"(obtained":[88],"paracentesis)":[90],"was":[91],"performed.":[92],"RESULTS:":[93],"Cells":[94],"reacted":[96],"anti-herpes":[98],"virus":[100],"type":[101],"(HSV-1)":[103],"antibody":[104],"were":[105,119],"detected":[106,120],"on":[107,133],"impression":[108],"cytology,":[109],"DNA":[111,117],"fragments":[112],"corresponding":[113],"to":[114,142],"HSV-1":[116],"sequence":[118],"in":[121],"humor.":[124],"CONCLUSION:":[125],"This":[126],"shows":[128],"may,":[132],"rare":[134],"occasions,":[135],"be":[136],"associated":[137],"secondary":[141],"HSV-1.":[143]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2016-06-24T00:00:00"}