{"id":"https://openalex.org/W2016487115","doi":"https://doi.org/10.1006/dbio.2000.9881","title":"The Membrane Glycoprotein gp150 Is Encoded by the lagC Gene and Mediates Cell\u2013Cell Adhesion by Heterophilic Binding during Dictyostelium Development","display_name":"The Membrane Glycoprotein gp150 Is Encoded by the lagC Gene and Mediates Cell\u2013Cell Adhesion by Heterophilic Binding during Dictyostelium Development","publication_year":2000,"publication_date":"2000-11-01","ids":{"openalex":"https://openalex.org/W2016487115","doi":"https://doi.org/10.1006/dbio.2000.9881","mag":"2016487115","pmid":"https://pubmed.ncbi.nlm.nih.gov/11071787"},"language":"en","primary_location":{"id":"doi:10.1006/dbio.2000.9881","doi":"https://doi.org/10.1006/dbio.2000.9881","is_oa":true,"landing_page_url":"https://doi.org/10.1006/dbio.2000.9881","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0012160600998816/pdf","source":{"id":"https://openalex.org/S136634221","display_name":"Developmental Biology","issn_l":"0012-1606","issn":["0012-1606","1095-564X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.sciencedirect.com/science/article/pii/S0012160600998816/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Jun Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Jun Wang","raw_affiliation_strings":["Banting and Best Department of Medical Research, University of Toronto, Canada","Banting and Best Department of Medical Research","Department of Biochemistry, University of Toronto, Toronto, Ontario, M5G 1L6, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Banting and Best Department of Medical Research, University of Toronto, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Banting and Best Department of Medical Research","institution_ids":[]},{"raw_affiliation_string":"Department of Biochemistry, University of Toronto, Toronto, Ontario, M5G 1L6, Canada","institution_ids":["https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113747953","display_name":"Hou Liansheng","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Liansheng Hou","raw_affiliation_strings":["Banting and Best Department of Medical Research"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Banting and Best Department of Medical Research","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109083161","display_name":"Donald E. Awrey","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Don Awrey","raw_affiliation_strings":["Department of Biochemistry, University of Toronto, Toronto, Ontario, M5G 1L6, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, University of Toronto, Toronto, Ontario, M5G 1L6, Canada","institution_ids":["https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014612742","display_name":"William F. Loomis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William F. Loomis","raw_affiliation_strings":["University of California at San Diego, La Jolla, California, 92037"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California at San Diego, La Jolla, California, 92037","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019725371","display_name":"Richard Firtel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard A. Firtel","raw_affiliation_strings":["University of California at San Diego, La Jolla, California, 92037"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California at San Diego, La Jolla, California, 92037","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111684195","display_name":"Chi\u2010Hung Siu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Chi-Hung Siu","raw_affiliation_strings":["Banting and Best Department of Medical Research","Department of Biochemistry, University of Toronto, Toronto, Ontario, M5G 1L6, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Banting and Best Department of Medical Research","institution_ids":[]},{"raw_affiliation_string":"Department of Biochemistry, University of Toronto, Toronto, Ontario, M5G 1L6, Canada","institution_ids":["https://openalex.org/I185261750"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5111684195"],"corresponding_institution_ids":["https://openalex.org/I185261750"],"apc_list":{"value":3550,"currency":"USD","value_usd":3550},"apc_paid":null,"fwci":2.209,"has_fulltext":true,"cited_by_count":52,"citation_normalized_percentile":{"value":0.85976376,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"227","issue":"2","first_page":"734","last_page":"745"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.8130000233650208,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.8130000233650208,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.11289999634027481,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13362","display_name":"Slime Mold and Myxomycetes Research","score":0.03500000014901161,"subfield":{"id":"https://openalex.org/subfields/1105","display_name":"Ecology, Evolution, Behavior and Systematics"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gp150","display_name":"gp150","score":0.9940000176429749},{"id":"https://openalex.org/keywords/dictyostelium","display_name":"Dictyostelium","score":0.9399999976158142},{"id":"https://openalex.org/keywords/cell-cell-adhesion","display_name":"cell-cell adhesion","score":0.9890000224113464},{"id":"https://openalex.org/keywords/heterophilic-binding","display_name":"heterophilic binding","score":0.968999981880188},{"id":"https://openalex.org/keywords/cell-aggregation","display_name":"cell aggregation","score":0.7400000095367432},{"id":"https://openalex.org/keywords/gp80","display_name":"gp80","score":0.8130000233650208},{"id":"https://openalex.org/keywords/membrane-glycoproteins","display_name":"membrane glycoproteins","score":0.9120000004768372},{"id":"https://openalex.org/keywords/cell-type-specification","display_name":"cell specification","score":0.5379999876022339},{"id":"https://openalex.org/keywords/morphogenesis","display_name":"morphogenesis","score":0.6650000214576721}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.739027738571167},{"id":"https://openalex.org/C85789140","wikidata":"https://www.wikidata.org/wiki/Q187640","display_name":"Cell adhesion","level":3,"score":0.6184076070785522},{"id":"https://openalex.org/C2775969001","wikidata":"https://www.wikidata.org/wiki/Q134351","display_name":"Dictyostelium discoideum","level":3,"score":0.5695919990539551},{"id":"https://openalex.org/C2775889303","wikidata":"https://www.wikidata.org/wiki/Q17146891","display_name":"Dictyostelium","level":3,"score":0.5422845482826233},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5394102334976196},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.5340349674224854},{"id":"https://openalex.org/C40692019","wikidata":"https://www.wikidata.org/wiki/Q815547","display_name":"Morphogenesis","level":3,"score":0.4732666015625},{"id":"https://openalex.org/C108625454","wikidata":"https://www.wikidata.org/wiki/Q187126","display_name":"Glycoprotein","level":2,"score":0.46769312024116516},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.4580283761024475},{"id":"https://openalex.org/C16224149","wikidata":"https://www.wikidata.org/wiki/Q187637","display_name":"Cell adhesion molecule","level":2,"score":0.41034388542175293},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4056662321090698},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.33782899379730225},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1929267942905426}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000913","descriptor_name":"Antibodies, Protozoan","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D004023","descriptor_name":"Dictyostelium","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D004023","descriptor_name":"Dictyostelium","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D004023","descriptor_name":"Dictyostelium","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015800","descriptor_name":"Protozoan Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D015800","descriptor_name":"Protozoan Proteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D015800","descriptor_name":"Protozoan Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D017125","descriptor_name":"Genes, Protozoan","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017931","descriptor_name":"DNA Primers","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019032","descriptor_name":"Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1006/dbio.2000.9881","doi":"https://doi.org/10.1006/dbio.2000.9881","is_oa":true,"landing_page_url":"https://doi.org/10.1006/dbio.2000.9881","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0012160600998816/pdf","source":{"id":"https://openalex.org/S136634221","display_name":"Developmental Biology","issn_l":"0012-1606","issn":["0012-1606","1095-564X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental Biology","raw_type":"journal-article"},{"id":"pmid:11071787","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11071787","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental biology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1006/dbio.2000.9881","doi":"https://doi.org/10.1006/dbio.2000.9881","is_oa":true,"landing_page_url":"https://doi.org/10.1006/dbio.2000.9881","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0012160600998816/pdf","source":{"id":"https://openalex.org/S136634221","display_name":"Developmental Biology","issn_l":"0012-1606","issn":["0012-1606","1095-564X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G8718501104","display_name":"A Two-Component Signal Transduction Pathway in DictyosteliumDevelopment","funder_award_id":"9728463","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320322725","display_name":"China Scholarship Council","ror":"https://ror.org/04atp4p48"},{"id":"https://openalex.org/F4320324195","display_name":"Medical Research Council Canada","ror":"https://ror.org/01gavpb45"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2016487115.pdf","grobid_xml":"https://content.openalex.org/works/W2016487115.grobid-xml"},"referenced_works_count":42,"referenced_works":["https://openalex.org/W1147879691","https://openalex.org/W1536436988","https://openalex.org/W1569431675","https://openalex.org/W1640981414","https://openalex.org/W1965308709","https://openalex.org/W1965871391","https://openalex.org/W1972215776","https://openalex.org/W1977729177","https://openalex.org/W1979111381","https://openalex.org/W1981613908","https://openalex.org/W1985324583","https://openalex.org/W2004474008","https://openalex.org/W2005272332","https://openalex.org/W2012449043","https://openalex.org/W2020343823","https://openalex.org/W2023511136","https://openalex.org/W2029193532","https://openalex.org/W2052217722","https://openalex.org/W2052876125","https://openalex.org/W2057255751","https://openalex.org/W2059442542","https://openalex.org/W2063056851","https://openalex.org/W2078594804","https://openalex.org/W2082246519","https://openalex.org/W2084007133","https://openalex.org/W2084879924","https://openalex.org/W2088294880","https://openalex.org/W2100837269","https://openalex.org/W2109677752","https://openalex.org/W2120492537","https://openalex.org/W2125703976","https://openalex.org/W2139594581","https://openalex.org/W2141271321","https://openalex.org/W2144634347","https://openalex.org/W2148460311","https://openalex.org/W2163821720","https://openalex.org/W2172160601","https://openalex.org/W2172205740","https://openalex.org/W2314225431","https://openalex.org/W2743682641","https://openalex.org/W2910895201","https://openalex.org/W6786186127"],"related_works":["https://openalex.org/W1640981414","https://openalex.org/W2365282655","https://openalex.org/W2071275887","https://openalex.org/W2058840085","https://openalex.org/W1566627072","https://openalex.org/W2141271321","https://openalex.org/W2360170398","https://openalex.org/W2084879924","https://openalex.org/W2372638689","https://openalex.org/W1997704420"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}