{"id":"https://openalex.org/W2016471790","doi":"https://doi.org/10.1523/jneurosci.4203-07.2008","title":"InDRG11Knock-Out Mice, Trigeminal Cell Death Is Extensive and Does Not Account for Failed Brainstem Patterning","display_name":"InDRG11Knock-Out Mice, Trigeminal Cell Death Is Extensive and Does Not Account for Failed Brainstem Patterning","publication_year":2008,"publication_date":"2008-04-02","ids":{"openalex":"https://openalex.org/W2016471790","doi":"https://doi.org/10.1523/jneurosci.4203-07.2008","mag":"2016471790","pmid":"https://pubmed.ncbi.nlm.nih.gov/18385316","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2596061"},"language":"en","primary_location":{"id":"doi:10.1523/jneurosci.4203-07.2008","doi":"https://doi.org/10.1523/jneurosci.4203-07.2008","is_oa":true,"landing_page_url":"https://doi.org/10.1523/jneurosci.4203-07.2008","pdf_url":"https://www.jneurosci.org/content/jneuro/28/14/3577.full.pdf","source":{"id":"https://openalex.org/S5555990","display_name":"Journal of Neuroscience","issn_l":"0270-6474","issn":["0270-6474","1529-2401"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319739","host_organization_name":"Society for Neuroscience","host_organization_lineage":["https://openalex.org/P4310319739"],"host_organization_lineage_names":["Society for Neuroscience"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Neuroscience","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.jneurosci.org/content/jneuro/28/14/3577.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108404297","display_name":"Mark F. Jacquin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark F. Jacquin","raw_affiliation_strings":["Department of Neurology, Washington University School of Medicine, St. Louis, Missouri 63110, USA. jacquinm@neuro.wustl.edu","Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, 63110, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Washington University School of Medicine, St. Louis, Missouri 63110, USA. jacquinm@neuro.wustl.edu","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, 63110, USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Joop J. A. Arends","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joop J. A. Arends","raw_affiliation_strings":["Department of Neurology, Box 8111, Washington University School of Medicine, St. Louis, MO 63110","Departments of 1 Neurology,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Box 8111, Washington University School of Medicine, St. Louis, MO 63110","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Departments of 1 Neurology,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074418639","display_name":"Chuanxi Xiang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chuanxi Xiang","raw_affiliation_strings":["Anesthesiology,","Developmental Biology, Washington University School of Medicine, St. Louis, Missouri 63110, and","Psychiatry, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anesthesiology,","institution_ids":[]},{"raw_affiliation_string":"Developmental Biology, Washington University School of Medicine, St. Louis, Missouri 63110, and","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Psychiatry, and","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103045984","display_name":"Lee A. Shapiro","orcid":"https://orcid.org/0000-0002-8368-1854","observed_orcids":["https://orcid.org/0000-0002-8368-1854","https://orcid.org/0000-0003-0575-7662"]},"institutions":[{"id":"https://openalex.org/I204250578","display_name":"University of California, Irvine","ror":"https://ror.org/04gyf1771","country_code":"US","type":"education","lineage":["https://openalex.org/I204250578"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lee A. Shapiro","raw_affiliation_strings":["Department of Anatomy and Neurobiology, School of Medicine, University of California at Irvine, Irvine, California 92697"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy and Neurobiology, School of Medicine, University of California at Irvine, Irvine, California 92697","institution_ids":["https://openalex.org/I204250578"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109171993","display_name":"Charles E. Ribak","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204250578","display_name":"University of California, Irvine","ror":"https://ror.org/04gyf1771","country_code":"US","type":"education","lineage":["https://openalex.org/I204250578"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charles E. Ribak","raw_affiliation_strings":["Department of Anatomy and Neurobiology, School of Medicine, University of California at Irvine, Irvine, California 92697"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy and Neurobiology, School of Medicine, University of California at Irvine, Irvine, California 92697","institution_ids":["https://openalex.org/I204250578"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5025792713","display_name":"Zhou\u2010Feng Chen","orcid":"https://orcid.org/0000-0002-6859-7910","observed_orcids":["https://orcid.org/0000-0002-6859-7910"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhou-Feng Chen","raw_affiliation_strings":["Anesthesiology,","Developmental Biology, Washington University School of Medicine, St. Louis, Missouri 63110, and","Psychiatry, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anesthesiology,","institution_ids":[]},{"raw_affiliation_string":"Developmental Biology, Washington University School of Medicine, St. Louis, Missouri 63110, and","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Psychiatry, and","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.5085,"has_fulltext":true,"cited_by_count":20,"citation_normalized_percentile":{"value":0.60268402,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"28","issue":"14","first_page":"3577","last_page":"3585"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.8086000084877014,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.8086000084877014,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.15729999542236328,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12061","display_name":"Axon Guidance and Neuronal Signaling","score":0.0038999998942017555,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuronal-death","display_name":"neuronal cell death","score":0.722000002861023},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.9850000143051147},{"id":"https://openalex.org/keywords/necrosis","display_name":"necrosis","score":0.8610000014305115},{"id":"https://openalex.org/keywords/bax","display_name":"Bax","score":0.7540000081062317},{"id":"https://openalex.org/keywords/homeodomain-transcription-factor","display_name":"homeodomain transcription factor","score":0.7549999952316284},{"id":"https://openalex.org/keywords/knockout-mice","display_name":"knockout mice","score":0.48899999260902405}],"concepts":[{"id":"https://openalex.org/C551621295","wikidata":"https://www.wikidata.org/wiki/Q182228","display_name":"Brainstem","level":2,"score":0.7981815338134766},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5554046034812927},{"id":"https://openalex.org/C182704531","wikidata":"https://www.wikidata.org/wiki/Q1364740","display_name":"Knockout mouse","level":3,"score":0.5111070275306702},{"id":"https://openalex.org/C2796436","wikidata":"https://www.wikidata.org/wiki/Q3109064","display_name":"Gene knockin","level":3,"score":0.4639183282852173},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.445684552192688},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1760166883468628},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.10908335447311401}],"mesh":[{"descriptor_ui":"D000344","descriptor_name":"Afferent Pathways","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":false},{"descriptor_ui":"D000344","descriptor_name":"Afferent Pathways","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D000344","descriptor_name":"Afferent Pathways","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D000704","descriptor_name":"Analysis of Variance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000831","descriptor_name":"Animals, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001933","descriptor_name":"Brain Stem","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true},{"descriptor_ui":"D001933","descriptor_name":"Brain Stem","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":false},{"descriptor_ui":"D001933","descriptor_name":"Brain Stem","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D002452","descriptor_name":"Cell Count","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004622","descriptor_name":"Embryo, Mammalian","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009419","descriptor_name":"Nerve Tissue Proteins","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":true},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":true},{"descriptor_ui":"D014278","descriptor_name":"Trigeminal Nuclei","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D014738","descriptor_name":"Vibrissae","qualifier_ui":"Q000294","qualifier_name":"innervation","is_major_topic":false},{"descriptor_ui":"D016923","descriptor_name":"Cell Death","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018398","descriptor_name":"Homeodomain Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019521","descriptor_name":"Body Patterning","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D046529","descriptor_name":"Microscopy, Electron, Transmission","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D048429","descriptor_name":"Cell Size","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051028","descriptor_name":"bcl-2-Associated X Protein","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1523/jneurosci.4203-07.2008","doi":"https://doi.org/10.1523/jneurosci.4203-07.2008","is_oa":true,"landing_page_url":"https://doi.org/10.1523/jneurosci.4203-07.2008","pdf_url":"https://www.jneurosci.org/content/jneuro/28/14/3577.full.pdf","source":{"id":"https://openalex.org/S5555990","display_name":"Journal of Neuroscience","issn_l":"0270-6474","issn":["0270-6474","1529-2401"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319739","host_organization_name":"Society for Neuroscience","host_organization_lineage":["https://openalex.org/P4310319739"],"host_organization_lineage_names":["Society for Neuroscience"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Neuroscience","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2596061","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2596061","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Neurosci","raw_type":"Text"},{"id":"pmid:18385316","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18385316","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of neuroscience : the official journal of the Society for Neuroscience","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.325.7577","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.325.7577","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.jneurosci.org/content/28/14/3577.full.pdf","raw_type":"text"},{"id":"pmh:oai:escholarship.org/ark:/13030/qt242405w0","doi":null,"is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/242405w0","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 28, iss 14","raw_type":"article"},{"id":"pmh:oai:escholarship.org:ark:/13030/qt242405w0","doi":null,"is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/242405w0","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Neuroscience, vol 28, iss 14","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1523/jneurosci.4203-07.2008","doi":"https://doi.org/10.1523/jneurosci.4203-07.2008","is_oa":true,"landing_page_url":"https://doi.org/10.1523/jneurosci.4203-07.2008","pdf_url":"https://www.jneurosci.org/content/jneuro/28/14/3577.full.pdf","source":{"id":"https://openalex.org/S5555990","display_name":"Journal of Neuroscience","issn_l":"0270-6474","issn":["0270-6474","1529-2401"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319739","host_organization_name":"Society for Neuroscience","host_organization_lineage":["https://openalex.org/P4310319739"],"host_organization_lineage_names":["Society for Neuroscience"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Neuroscience","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.6240000128746033}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5299999713897705}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2766790882","display_name":"Seizure-Induced Neurogenesis In The Dentate Gyrus","funder_award_id":"R01NS038331","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G3156001389","display_name":"Transcriptional Mechanisms of Trigeminal Development","funder_award_id":"R01NS046036","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G496599981","display_name":null,"funder_award_id":"R01 NS38331","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G5610994899","display_name":"Molecular Mechanisms of Trigeminal Development","funder_award_id":"P01NS049048","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2016471790.pdf","grobid_xml":"https://content.openalex.org/works/W2016471790.grobid-xml"},"referenced_works_count":50,"referenced_works":["https://openalex.org/W4183726","https://openalex.org/W406526061","https://openalex.org/W1505976679","https://openalex.org/W1523167124","https://openalex.org/W1548510837","https://openalex.org/W1561430338","https://openalex.org/W1561541164","https://openalex.org/W1564635029","https://openalex.org/W1571283914","https://openalex.org/W1678646792","https://openalex.org/W1899716694","https://openalex.org/W1963989698","https://openalex.org/W1967823521","https://openalex.org/W1974651731","https://openalex.org/W1976441097","https://openalex.org/W1979386469","https://openalex.org/W1981757532","https://openalex.org/W1985442766","https://openalex.org/W1989670552","https://openalex.org/W1992033502","https://openalex.org/W1992682918","https://openalex.org/W1994047748","https://openalex.org/W1996495340","https://openalex.org/W1998956090","https://openalex.org/W2000184718","https://openalex.org/W2010395737","https://openalex.org/W2012337697","https://openalex.org/W2013059756","https://openalex.org/W2014140314","https://openalex.org/W2021358642","https://openalex.org/W2021770553","https://openalex.org/W2022341585","https://openalex.org/W2027135582","https://openalex.org/W2038701340","https://openalex.org/W2045434155","https://openalex.org/W2061245269","https://openalex.org/W2061737093","https://openalex.org/W2070811346","https://openalex.org/W2079479433","https://openalex.org/W2085069656","https://openalex.org/W2087768763","https://openalex.org/W2121255525","https://openalex.org/W2125963323","https://openalex.org/W2138066183","https://openalex.org/W2140473620","https://openalex.org/W2142401824","https://openalex.org/W2155214369","https://openalex.org/W2162710298","https://openalex.org/W2164180561","https://openalex.org/W2165892113"],"related_works":["https://openalex.org/W2073554209","https://openalex.org/W2085069656","https://openalex.org/W2125963323","https://openalex.org/W2000853507","https://openalex.org/W2074043952","https://openalex.org/W2005891284","https://openalex.org/W2077960291","https://openalex.org/W2055971511","https://openalex.org/W2013059756","https://openalex.org/W2017772219"],"abstract_inverted_index":{"A":[0,224],"previous":[1],"study":[2],"(Ding":[3],"et":[4],"al.,":[5],"2003)":[6],"showed":[7],"that":[8,64,76],"the":[9,20,25,32,62,72,95,111,124,135,143,219,222,232],"homeodomain":[10],"transcription":[11],"factor":[12],"DRG11":[13,42,52,65,162,228],"is":[14,38,66,80,209],"necessary":[15],"for":[16,29,68],"pattern":[17,45,84,121,216,235],"formation":[18,122,217],"in":[19,51,71,94,110,123,142,169,180,193,218],"trigeminal":[21],"nucleus":[22,28],"principalis":[23],"(PrV),":[24],"requisite":[26],"brainstem":[27],"development":[30],"of":[31,137,199,214,221],"whisker-to-barrel":[33],"cortex":[34],"pathway.":[35],"However,":[36],"it":[37],"not":[39,116,210],"known":[40],"how":[41],"contributes":[43],"to":[44,60,82,118,155,172],"formation.":[46],"Anatomical":[47],"studies":[48],"were":[49,108,167],"performed":[50],"knock-out":[53],"(-/-)":[54],"and":[55,75,99,132,146,164,185,202],"DRG11/Bax":[56,186],"double":[57,187],"-/-":[58,188],"mice":[59,89,166],"test":[61],"hypotheses":[63],"required":[67],"neuronal":[69],"survival":[70],"V":[73,96,101,200],"pathway":[74,226],"PrV":[77,138,174,203,220,234],"cell":[78,92,113,139,151,207],"death":[79,114,140,152,208],"sufficient":[81,212],"explain":[83,119],"alterations.":[85],"At":[86],"birth,":[87],"DRG11(-/-)":[88,181,184],"had":[90],"equivalent":[91],"loss":[93],"ganglion,":[97],"PrV,":[98,195],"spinal":[100],"subnucleus":[102],"interpolaris":[103],"(SpVi).":[104],"Because":[105],"whisker-related":[106,191],"patterns":[107],"normal":[109],"SpVi,":[112],"would":[115],"appear":[117],"failed":[120,215],"mutant":[125],"PrV.":[126],"Electron":[127],"microscopy":[128],"revealed":[129],"exuberant":[130,178],"apoptosis":[131,179],"necrosis":[133],"as":[134],"mechanisms":[136],"occurring":[141],"late":[144],"prenatal":[145],"newborn":[147],"DRG11(-/-),":[148],"when":[149],"such":[150],"was":[153],"up":[154],"six":[156],"times":[157],"more":[158],"prevalent":[159],"than":[160],"normal.":[161],"heterozygote":[163],"Bax(-/-)":[165],"crossed":[168],"an":[170],"attempt":[171],"dissociate":[173],"patterning":[175,192],"anomalies":[176],"from":[177],"mice.":[182],"Both":[183],"mutants":[189],"lacked":[190],"their":[194],"despite":[196],"Bax(-/-)-induced":[197],"rescue":[198],"ganglion":[201],"cells.":[204],"Thus,":[205],"apoptotic":[206],"a":[211],"cause":[213],"DRG11(-/-).":[223],"signaling":[225],"involving":[227],"may,":[229],"therefore,":[230],"be":[231],"elusive":[233],"maker.":[236]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":6}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}