{"id":"https://openalex.org/W2016405036","doi":"https://doi.org/10.1016/0166-2236(95)93923-l","title":"Retrograde signaling at GABAA-receptor synapses in the mammalian CNS","display_name":"Retrograde signaling at GABAA-receptor synapses in the mammalian CNS","publication_year":1995,"publication_date":"1995-08-01","ids":{"openalex":"https://openalex.org/W2016405036","doi":"https://doi.org/10.1016/0166-2236(95)93923-l","mag":"2016405036","pmid":"https://pubmed.ncbi.nlm.nih.gov/7482793"},"language":"en","primary_location":{"id":"doi:10.1016/0166-2236(95)93923-l","doi":"https://doi.org/10.1016/0166-2236(95)93923-l","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0166-2236(95)93923-l","pdf_url":null,"source":{"id":"https://openalex.org/S114966740","display_name":"Trends in Neurosciences","issn_l":"0166-2236","issn":["0166-2236","1878-108X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trends in Neurosciences","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089589290","display_name":"Bradley E. Alger","orcid":"https://orcid.org/0000-0002-2385-9876","observed_orcids":["https://orcid.org/0000-0002-2385-9876"]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"B.E. Alger","raw_affiliation_strings":["Dept of Physiology, University of Maryland School of Medicine, Baltimore 21201, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept of Physiology, University of Maryland School of Medicine, Baltimore 21201, USA","institution_ids":["https://openalex.org/I126744593"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085045352","display_name":"Thomas A. Pitler","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"T.A. Pitler","raw_affiliation_strings":["B.E. Alger and T.A. Pitler are at the Dept of Physiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"B.E. Alger and T.A. Pitler are at the Dept of Physiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA","institution_ids":["https://openalex.org/I126744593"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I126744593"],"apc_list":{"value":7030,"currency":"USD","value_usd":7030},"apc_paid":null,"fwci":0.4972,"has_fulltext":false,"cited_by_count":93,"citation_normalized_percentile":{"value":0.53594771,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"18","issue":"8","first_page":"333","last_page":"340"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/retrograde-signaling","display_name":"retrograde signaling","score":0.9909999966621399},{"id":"https://openalex.org/keywords/gaba-a-receptor","display_name":"GABAA receptor","score":0.9309999942779541},{"id":"https://openalex.org/keywords/depolarization-induced-suppression-of-inhibition","display_name":"depolarization-induced suppression of inhibition","score":0.9380000233650208},{"id":"https://openalex.org/keywords/inhibitory-interneurons","display_name":"inhibitory interneurons","score":0.7580000162124634},{"id":"https://openalex.org/keywords/gaba-release","display_name":"GABA release","score":0.7940000295639038},{"id":"https://openalex.org/keywords/postsynaptic-inhibition","display_name":"postsynaptic inhibition","score":0.7110000252723694},{"id":"https://openalex.org/keywords/hippocampus","display_name":"hippocampus","score":0.800000011920929},{"id":"https://openalex.org/keywords/cerebellum","display_name":"cerebellum","score":0.9990000128746033},{"id":"https://openalex.org/keywords/calcium-signaling","display_name":"calcium signaling","score":0.5440000295639038},{"id":"https://openalex.org/keywords/synaptic-plasticity","display_name":"synaptic plasticity","score":0.5199999809265137}],"concepts":[{"id":"https://openalex.org/C168258287","wikidata":"https://www.wikidata.org/wiki/Q60147","display_name":"GABAA receptor","level":3,"score":0.8516131639480591},{"id":"https://openalex.org/C17077164","wikidata":"https://www.wikidata.org/wiki/Q1185869","display_name":"Inhibitory postsynaptic potential","level":2,"score":0.7893239259719849},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.7720107436180115},{"id":"https://openalex.org/C197341189","wikidata":"https://www.wikidata.org/wiki/Q863533","display_name":"Postsynaptic potential","level":3,"score":0.7667167782783508},{"id":"https://openalex.org/C112592302","wikidata":"https://www.wikidata.org/wiki/Q1207387","display_name":"Excitatory postsynaptic potential","level":3,"score":0.6985931396484375},{"id":"https://openalex.org/C2779296341","wikidata":"https://www.wikidata.org/wiki/Q1500732","display_name":"Interneuron","level":3,"score":0.5358700752258301},{"id":"https://openalex.org/C200170125","wikidata":"https://www.wikidata.org/wiki/Q969316","display_name":"Neurotransmission","level":3,"score":0.5343626737594604},{"id":"https://openalex.org/C2910581834","wikidata":"https://www.wikidata.org/wiki/Q1207387","display_name":"Postsynaptic Current","level":4,"score":0.5265840888023376},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4862424433231354},{"id":"https://openalex.org/C9224880","wikidata":"https://www.wikidata.org/wiki/Q798179","display_name":"GABAA-rho receptor","level":4,"score":0.47184446454048157},{"id":"https://openalex.org/C194082555","wikidata":"https://www.wikidata.org/wiki/Q7317034","display_name":"Retrograde signaling","level":3,"score":0.4713774621486664},{"id":"https://openalex.org/C127445978","wikidata":"https://www.wikidata.org/wiki/Q187181","display_name":"Synapse","level":2,"score":0.4481215476989746},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.43117856979370117},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.37021249532699585},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3545075058937073},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3127894997596741},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.170354962348938},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.10614049434661865}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002490","descriptor_name":"Central Nervous System","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011963","descriptor_name":"Receptors, GABA-A","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D013569","descriptor_name":"Synapses","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/0166-2236(95)93923-l","doi":"https://doi.org/10.1016/0166-2236(95)93923-l","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0166-2236(95)93923-l","pdf_url":null,"source":{"id":"https://openalex.org/S114966740","display_name":"Trends in Neurosciences","issn_l":"0166-2236","issn":["0166-2236","1878-108X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trends in Neurosciences","raw_type":"journal-article"},{"id":"pmid:7482793","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7482793","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trends in neurosciences","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.46810001134872437,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1096980520","display_name":null,"funder_award_id":"NS-30219","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G1154560250","display_name":null,"funder_award_id":"NS-22010","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G4787986780","display_name":"ELECTROPHYSIOLOGY OF THE PI-PKC SYSTEM IN HIPPOCAMPUS","funder_award_id":"5r01ns022010-12","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6830107122","display_name":"Regulation of Inhibition in Hippocampus","funder_award_id":"R01NS030219","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":40,"referenced_works":["https://openalex.org/W1508825618","https://openalex.org/W1762877386","https://openalex.org/W1774176118","https://openalex.org/W1906485248","https://openalex.org/W1965911542","https://openalex.org/W1970096704","https://openalex.org/W1971273652","https://openalex.org/W1971367829","https://openalex.org/W1984405279","https://openalex.org/W1984994314","https://openalex.org/W1990614791","https://openalex.org/W1990712757","https://openalex.org/W1991218496","https://openalex.org/W1991376825","https://openalex.org/W1991905988","https://openalex.org/W1996241414","https://openalex.org/W1996382884","https://openalex.org/W2003542304","https://openalex.org/W2009074192","https://openalex.org/W2011330893","https://openalex.org/W2016943305","https://openalex.org/W2022218885","https://openalex.org/W2024328209","https://openalex.org/W2026199143","https://openalex.org/W2026708081","https://openalex.org/W2028045674","https://openalex.org/W2030145065","https://openalex.org/W2033399950","https://openalex.org/W2036807698","https://openalex.org/W2049511526","https://openalex.org/W2057185700","https://openalex.org/W2083254238","https://openalex.org/W2085580985","https://openalex.org/W2086961654","https://openalex.org/W2088296164","https://openalex.org/W2093267069","https://openalex.org/W2102268999","https://openalex.org/W2117583411","https://openalex.org/W2169280213","https://openalex.org/W2171336978"],"related_works":["https://openalex.org/W2054922141","https://openalex.org/W1968083340","https://openalex.org/W2131007359","https://openalex.org/W7098720294","https://openalex.org/W11492871","https://openalex.org/W4232777723","https://openalex.org/W2040185876","https://openalex.org/W2139191974","https://openalex.org/W1991905988","https://openalex.org/W2288208123"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}