{"id":"https://openalex.org/W2016367295","doi":"https://doi.org/10.1111/j.1527-5299.2007.06595.x","title":"PARP Inhibitors and Heart Failure\u2014Translational Medicine Caught in the Act","display_name":"PARP Inhibitors and Heart Failure\u2014Translational Medicine Caught in the Act","publication_year":2007,"publication_date":"2007-03-01","ids":{"openalex":"https://openalex.org/W2016367295","doi":"https://doi.org/10.1111/j.1527-5299.2007.06595.x","mag":"2016367295","pmid":"https://pubmed.ncbi.nlm.nih.gov/17392615"},"language":"en","primary_location":{"id":"doi:10.1111/j.1527-5299.2007.06595.x","doi":"https://doi.org/10.1111/j.1527-5299.2007.06595.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1527-5299.2007.06595.x","pdf_url":null,"source":{"id":"https://openalex.org/S26432035","display_name":"Congestive Heart Failure","issn_l":"1527-5299","issn":["1527-5299","1751-7133"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Congestive Heart Failure","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067997833","display_name":"George W. Booz","orcid":"https://orcid.org/0000-0003-1478-9615","observed_orcids":["https://orcid.org/0000-0003-1478-9615"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"George W. Booz","raw_affiliation_strings":["Cardiovascular Research Institute, Texas A and M College of Medicine, Temple, TX 76504, USA. gbooz@medicine.tamhsc.edu","Cardiovascular Research Institute, Texas A and M College of Medicine, Temple, TX 76504, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Research Institute, Texas A and M College of Medicine, Temple, TX 76504, USA. gbooz@medicine.tamhsc.edu","institution_ids":[]},{"raw_affiliation_string":"Cardiovascular Research Institute, Texas A and M College of Medicine, Temple, TX 76504, USA","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5067997833"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.1342,"has_fulltext":false,"cited_by_count":18,"citation_normalized_percentile":{"value":0.14360509,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"13","issue":"2","first_page":"105","last_page":"112"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11914","display_name":"PARP inhibition in cancer therapy","score":0.9038000106811523,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11914","display_name":"PARP inhibition in cancer therapy","score":0.9038000106811523,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10198","display_name":"Heart Failure Treatment and Management","score":0.04439999908208847,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11962","display_name":"Cardiac Fibrosis and Remodeling","score":0.004600000102072954,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/parp-inhibitors","display_name":"PARP inhibitors","score":0.9980000257492065},{"id":"https://openalex.org/keywords/heart-failure","display_name":"heart failure","score":0.9940000176429749},{"id":"https://openalex.org/keywords/translational-research","display_name":"translational research","score":0.6980000138282776},{"id":"https://openalex.org/keywords/heart-failure-treatment","display_name":"heart failure treatment","score":0.8669999837875366},{"id":"https://openalex.org/keywords/drug-induced-cardiotoxicity","display_name":"drug-induced cardiotoxicity","score":0.5609999895095825}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7619450092315674},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.7558454275131226},{"id":"https://openalex.org/C2780129039","wikidata":"https://www.wikidata.org/wiki/Q1931107","display_name":"Section (typography)","level":2,"score":0.6726685762405396},{"id":"https://openalex.org/C82307848","wikidata":"https://www.wikidata.org/wiki/Q847520","display_name":"Audience measurement","level":2,"score":0.6247841715812683},{"id":"https://openalex.org/C128544194","wikidata":"https://www.wikidata.org/wiki/Q474859","display_name":"Translational research","level":2,"score":0.462100625038147},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.24873659014701843},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.14265206456184387},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.12067723274230957},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.06595191359519958},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.061400651931762695},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000067856","descriptor_name":"Poly(ADP-ribose) Polymerase Inhibitors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000067856","descriptor_name":"Poly(ADP-ribose) Polymerase Inhibitors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000067856","descriptor_name":"Poly(ADP-ribose) Polymerase Inhibitors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000071137","descriptor_name":"Poly (ADP-Ribose) Polymerase-1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000071137","descriptor_name":"Poly (ADP-Ribose) Polymerase-1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000071137","descriptor_name":"Poly (ADP-Ribose) Polymerase-1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004791","descriptor_name":"Enzyme Inhibitors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D004791","descriptor_name":"Enzyme Inhibitors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D004791","descriptor_name":"Enzyme Inhibitors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011065","descriptor_name":"Poly(ADP-ribose) Polymerases","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D011065","descriptor_name":"Poly(ADP-ribose) Polymerases","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D011065","descriptor_name":"Poly(ADP-ribose) Polymerases","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1527-5299.2007.06595.x","doi":"https://doi.org/10.1111/j.1527-5299.2007.06595.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1527-5299.2007.06595.x","pdf_url":null,"source":{"id":"https://openalex.org/S26432035","display_name":"Congestive Heart Failure","issn_l":"1527-5299","issn":["1527-5299","1751-7133"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Congestive Heart Failure","raw_type":"journal-article"},{"id":"pmid:17392615","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17392615","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Congestive heart failure (Greenwich, Conn.)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8560000061988831,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.4399999976158142,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":55,"referenced_works":["https://openalex.org/W1578747264","https://openalex.org/W1968757333","https://openalex.org/W1971284289","https://openalex.org/W1975077780","https://openalex.org/W1975087901","https://openalex.org/W1975846526","https://openalex.org/W1979992960","https://openalex.org/W1985740124","https://openalex.org/W1988194498","https://openalex.org/W1988948020","https://openalex.org/W1994051196","https://openalex.org/W1995860431","https://openalex.org/W2006806309","https://openalex.org/W2011955349","https://openalex.org/W2012049551","https://openalex.org/W2015640010","https://openalex.org/W2016164706","https://openalex.org/W2019240387","https://openalex.org/W2021645116","https://openalex.org/W2031718947","https://openalex.org/W2034753237","https://openalex.org/W2039199479","https://openalex.org/W2041956415","https://openalex.org/W2049868380","https://openalex.org/W2056477724","https://openalex.org/W2059397580","https://openalex.org/W2062071114","https://openalex.org/W2066204526","https://openalex.org/W2068342708","https://openalex.org/W2068670295","https://openalex.org/W2071034808","https://openalex.org/W2072528578","https://openalex.org/W2077926137","https://openalex.org/W2078168537","https://openalex.org/W2078283762","https://openalex.org/W2078628372","https://openalex.org/W2080367627","https://openalex.org/W2087521387","https://openalex.org/W2090257457","https://openalex.org/W2091035559","https://openalex.org/W2092638438","https://openalex.org/W2093619128","https://openalex.org/W2094205173","https://openalex.org/W2095798342","https://openalex.org/W2103259804","https://openalex.org/W2108979163","https://openalex.org/W2116176075","https://openalex.org/W2116830457","https://openalex.org/W2134392620","https://openalex.org/W2150202308","https://openalex.org/W2154587590","https://openalex.org/W2159882838","https://openalex.org/W2167712347","https://openalex.org/W2337014913","https://openalex.org/W4249572009"],"related_works":["https://openalex.org/W3025368967","https://openalex.org/W3094195962","https://openalex.org/W1988660609","https://openalex.org/W2290905967","https://openalex.org/W7127038124","https://openalex.org/W631846417","https://openalex.org/W4223466038","https://openalex.org/W2280256975","https://openalex.org/W4408140033","https://openalex.org/W4399305980"],"abstract_inverted_index":{"With":[0],"the":[1,17,20,35,38,44,50,57,74],"introduction":[2,58],"of":[3,19,37,52,59,76,82],"this":[4,60,69,91],"new":[5],"section,":[6],"\u201cSpotlight":[7],"on":[8,49],"Heart":[9,14],"Failure":[10,15],"Translational":[11],"Research,\u201d":[12],"Congestive":[13],"recognizes":[16],"importance":[18],"cutting\u2010edge":[21],"research":[22,78],"that":[23],"frequently":[24],"translates":[25],"to":[26,42],"clinical":[27],"practice":[28],"in":[29,40,79,103],"a":[30,47],"rapid":[31],"timeframe.":[32],"It":[33],"is":[34],"intent":[36],"Co\u2010Editors":[39,102],"Chief":[41,104],"provide":[43],"readership":[45],"with":[46],"window":[48],"future":[51],"heart":[53,83],"failure":[54,84],"therapeutics":[55],"through":[56],"section.":[61],"Dr.":[62],"George":[63],"W.":[64],"Booz,":[65],"Section":[66],"Editor":[67],"for":[68,85],"pivotal":[70],"area,":[71],"cordially":[72],"invites":[73],"submission":[75],"translational":[77],"all":[80],"aspects":[81],"review":[86],"and":[87,97],"potential":[88],"publication":[89],"within":[90],"section.\u2014John":[92],"E.":[93],"Strobeck,":[94],"MD,":[95,101],"PhD":[96],"Marc":[98],"A.":[99],"Silver,":[100]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2016-06-24T00:00:00"}