{"id":"https://openalex.org/W2016355432","doi":"https://doi.org/10.1016/j.micinf.2003.09.009","title":"Oxidative killing of microbes by neutrophils","display_name":"Oxidative killing of microbes by neutrophils","publication_year":2003,"publication_date":"2003-10-15","ids":{"openalex":"https://openalex.org/W2016355432","doi":"https://doi.org/10.1016/j.micinf.2003.09.009","mag":"2016355432","pmid":"https://pubmed.ncbi.nlm.nih.gov/14613774"},"language":"en","primary_location":{"id":"doi:10.1016/j.micinf.2003.09.009","doi":"https://doi.org/10.1016/j.micinf.2003.09.009","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.micinf.2003.09.009","pdf_url":null,"source":{"id":"https://openalex.org/S56361996","display_name":"Microbes and Infection","issn_l":"1286-4579","issn":["1286-4579","1769-714X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbes and Infection","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2016355432"],"child_works_count":0,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1016/j.micinf.2003.09.009","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007589576","display_name":"Dirk Roos","orcid":"https://orcid.org/0000-0001-5532-0202","observed_orcids":["https://orcid.org/0000-0001-5532-0202"]},"institutions":[{"id":"https://openalex.org/I2802928900","display_name":"Amsterdam UMC Location University of Amsterdam","ror":"https://ror.org/03t4gr691","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2802928900","https://openalex.org/I4210151833"]},{"id":"https://openalex.org/I3020210244","display_name":"Sanquin","ror":"https://ror.org/01fm2fv39","country_code":"NL","type":"nonprofit","lineage":["https://openalex.org/I3020210244"]},{"id":"https://openalex.org/I887064364","display_name":"University of Amsterdam","ror":"https://ror.org/04dkp9463","country_code":"NL","type":"education","lineage":["https://openalex.org/I887064364"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Dirk Roos","raw_affiliation_strings":["Sanquin Research at CLB, and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Plesmanlaan 125, 1066 CX Amsterdam, The Netherlands. d.roos@sanquin.nl","Sanquin Research at CLB, and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Plesmanlaan 125, 1066\u00a0CX Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sanquin Research at CLB, and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Plesmanlaan 125, 1066 CX Amsterdam, The Netherlands. d.roos@sanquin.nl","institution_ids":["https://openalex.org/I2802928900","https://openalex.org/I3020210244","https://openalex.org/I887064364"]},{"raw_affiliation_string":"Sanquin Research at CLB, and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Plesmanlaan 125, 1066\u00a0CX Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I2802928900","https://openalex.org/I3020210244","https://openalex.org/I887064364"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051042917","display_name":"Robin van Bruggen","orcid":"https://orcid.org/0000-0002-1676-0720","observed_orcids":["https://orcid.org/0000-0002-1676-0720"]},"institutions":[{"id":"https://openalex.org/I2802928900","display_name":"Amsterdam UMC Location University of Amsterdam","ror":"https://ror.org/03t4gr691","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2802928900","https://openalex.org/I4210151833"]},{"id":"https://openalex.org/I3020210244","display_name":"Sanquin","ror":"https://ror.org/01fm2fv39","country_code":"NL","type":"nonprofit","lineage":["https://openalex.org/I3020210244"]},{"id":"https://openalex.org/I4210096594","display_name":"Emma Kinderziekenhuis","ror":"https://ror.org/00bmv4102","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2802928900","https://openalex.org/I4210096594","https://openalex.org/I4210151833"]},{"id":"https://openalex.org/I4210151833","display_name":"Amsterdam University Medical Centers","ror":"https://ror.org/05grdyy37","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833"]},{"id":"https://openalex.org/I887064364","display_name":"University of Amsterdam","ror":"https://ror.org/04dkp9463","country_code":"NL","type":"education","lineage":["https://openalex.org/I887064364"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Robin van Bruggen","raw_affiliation_strings":["Emma Children\u2019s Hospital, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands","Sanquin Research at CLB, and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Plesmanlaan 125, 1066\u00a0CX Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Emma Children\u2019s Hospital, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I2802928900","https://openalex.org/I4210096594","https://openalex.org/I4210151833","https://openalex.org/I887064364"]},{"raw_affiliation_string":"Sanquin Research at CLB, and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Plesmanlaan 125, 1066\u00a0CX Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I2802928900","https://openalex.org/I3020210244","https://openalex.org/I887064364"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111849041","display_name":"Christof Meischl","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802928900","display_name":"Amsterdam UMC Location University of Amsterdam","ror":"https://ror.org/03t4gr691","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2802928900","https://openalex.org/I4210151833"]},{"id":"https://openalex.org/I3020210244","display_name":"Sanquin","ror":"https://ror.org/01fm2fv39","country_code":"NL","type":"nonprofit","lineage":["https://openalex.org/I3020210244"]},{"id":"https://openalex.org/I887064364","display_name":"University of Amsterdam","ror":"https://ror.org/04dkp9463","country_code":"NL","type":"education","lineage":["https://openalex.org/I887064364"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Christof Meischl","raw_affiliation_strings":["Sanquin Research at CLB, and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Plesmanlaan 125, 1066\u00a0CX Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sanquin Research at CLB, and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Plesmanlaan 125, 1066\u00a0CX Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I2802928900","https://openalex.org/I3020210244","https://openalex.org/I887064364"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5007589576"],"corresponding_institution_ids":["https://openalex.org/I2802928900","https://openalex.org/I3020210244","https://openalex.org/I887064364"],"apc_list":{"value":3510,"currency":"USD","value_usd":3510},"apc_paid":null,"fwci":1.7762,"has_fulltext":false,"cited_by_count":369,"citation_normalized_percentile":{"value":0.86151232,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"5","issue":"14","first_page":"1307","last_page":"1315"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11597","display_name":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11597","display_name":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11884","display_name":"Redox biology and oxidative stress","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12356","display_name":"Bioactive Compounds and Antitumor Agents","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neutrophils","display_name":"neutrophils","score":0.9829999804496765},{"id":"https://openalex.org/keywords/nadph-oxidase","display_name":"NADPH oxidase","score":0.7910000085830688},{"id":"https://openalex.org/keywords/superoxide-radicals","display_name":"superoxide","score":0.9210000038146973},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.9919999837875366},{"id":"https://openalex.org/keywords/microbial-killing","display_name":"microbial killing","score":0.6880000233650208},{"id":"https://openalex.org/keywords/phagocytosis","display_name":"phagocytosis","score":0.8830000162124634},{"id":"https://openalex.org/keywords/chronic-granulomatous-disease","display_name":"chronic granulomatous disease","score":0.9829999804496765},{"id":"https://openalex.org/keywords/phagocyte-dysfunction","display_name":"phagocyte dysfunction","score":0.6759999990463257}],"concepts":[{"id":"https://openalex.org/C2777700362","wikidata":"https://www.wikidata.org/wiki/Q107647","display_name":"Phagocyte","level":3,"score":0.9489891529083252},{"id":"https://openalex.org/C2778175462","wikidata":"https://www.wikidata.org/wiki/Q2165663","display_name":"Chronic granulomatous disease","level":2,"score":0.9369102120399475},{"id":"https://openalex.org/C2779719074","wikidata":"https://www.wikidata.org/wiki/Q2038057","display_name":"NADPH oxidase","level":3,"score":0.8643669486045837},{"id":"https://openalex.org/C2780795997","wikidata":"https://www.wikidata.org/wiki/Q413283","display_name":"Superoxide","level":3,"score":0.8333196640014648},{"id":"https://openalex.org/C182220744","wikidata":"https://www.wikidata.org/wiki/Q7251226","display_name":"Proteases","level":3,"score":0.7359240055084229},{"id":"https://openalex.org/C99971728","wikidata":"https://www.wikidata.org/wiki/Q838181","display_name":"Respiratory burst","level":2,"score":0.7133346796035767},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6937001943588257},{"id":"https://openalex.org/C48349386","wikidata":"https://www.wikidata.org/wiki/Q424361","display_name":"Reactive oxygen species","level":2,"score":0.6420297026634216},{"id":"https://openalex.org/C198677920","wikidata":"https://www.wikidata.org/wiki/Q3299937","display_name":"Neutrophile","level":3,"score":0.5873452425003052},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.5569731593132019},{"id":"https://openalex.org/C38485361","wikidata":"https://www.wikidata.org/wiki/Q576379","display_name":"Oxidase test","level":3,"score":0.544777512550354},{"id":"https://openalex.org/C160448771","wikidata":"https://www.wikidata.org/wiki/Q184726","display_name":"Phagocytosis","level":2,"score":0.5386767983436584},{"id":"https://openalex.org/C57600042","wikidata":"https://www.wikidata.org/wiki/Q227564","display_name":"Oxidative phosphorylation","level":2,"score":0.5118140578269958},{"id":"https://openalex.org/C19702531","wikidata":"https://www.wikidata.org/wiki/Q929966","display_name":"Mononuclear phagocyte system","level":2,"score":0.5108456015586853},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.49519529938697815},{"id":"https://openalex.org/C2775838275","wikidata":"https://www.wikidata.org/wiki/Q410776","display_name":"Superoxide dismutase","level":3,"score":0.4366539418697357},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4284300208091736},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.35504668951034546},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.17770516872406006}],"mesh":[{"descriptor_ui":"D001770","descriptor_name":"Blood Bactericidal Activity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006105","descriptor_name":"Granulomatous Disease, Chronic","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006105","descriptor_name":"Granulomatous Disease, Chronic","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009504","descriptor_name":"Neutrophils","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D009504","descriptor_name":"Neutrophils","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D010084","descriptor_name":"Oxidation-Reduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019255","descriptor_name":"NADPH Oxidases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.micinf.2003.09.009","doi":"https://doi.org/10.1016/j.micinf.2003.09.009","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.micinf.2003.09.009","pdf_url":null,"source":{"id":"https://openalex.org/S56361996","display_name":"Microbes and Infection","issn_l":"1286-4579","issn":["1286-4579","1769-714X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbes and Infection","raw_type":"journal-article"},{"id":"pmid:14613774","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14613774","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbes and infection","raw_type":"Journal Article"},{"id":"pmh:amcpub:oai:pure.amc.nl:publications/3dfac000-df8d-4595-82e8-777149ef71dd","doi":null,"is_oa":false,"landing_page_url":"https://pure.amc.nl/en/publications/oxidative-killing-of-microbes-by-neutrophils(3dfac000-df8d-4595-82e8-777149ef71dd).html","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Microbes and infection / Institut Pasteur, 5(14), 1307 - 1315. Elsevier Masson SAS","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pure.amsterdamumc.nl:openaire_cris_publications/8313816c-2335-4296-a6d0-c4d24fa338ac","doi":null,"is_oa":false,"landing_page_url":"https://pure.amsterdamumc.nl/en/publications/8313816c-2335-4296-a6d0-c4d24fa338ac","pdf_url":null,"source":{"id":"https://openalex.org/S7407055222","display_name":"Pure Amsterdam UMC","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Roos, D, van Bruggen, R & Meischl, C 2003, 'Oxidative killing of microbes by neutrophils', Microbes and infection / Institut Pasteur, vol. 5, no. 14, pp. 1307-1315. https://doi.org/10.1016/j.micinf.2003.09.009","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1016/j.micinf.2003.09.009","doi":"https://doi.org/10.1016/j.micinf.2003.09.009","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.micinf.2003.09.009","pdf_url":null,"source":{"id":"https://openalex.org/S56361996","display_name":"Microbes and Infection","issn_l":"1286-4579","issn":["1286-4579","1769-714X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbes and Infection","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8371999859809875}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W215195587","https://openalex.org/W1489696646","https://openalex.org/W1580256394","https://openalex.org/W1910966691","https://openalex.org/W1942012123","https://openalex.org/W1965980035","https://openalex.org/W1968212813","https://openalex.org/W1983148259","https://openalex.org/W1992034423","https://openalex.org/W2011125812","https://openalex.org/W2014165340","https://openalex.org/W2020319663","https://openalex.org/W2022385815","https://openalex.org/W2023822923","https://openalex.org/W2036811549","https://openalex.org/W2042360733","https://openalex.org/W2049206748","https://openalex.org/W2075238900","https://openalex.org/W2077421316","https://openalex.org/W2079527931","https://openalex.org/W2080643714","https://openalex.org/W2084699108","https://openalex.org/W2084814184","https://openalex.org/W2089887078","https://openalex.org/W2090524722","https://openalex.org/W2101745219","https://openalex.org/W2109610023","https://openalex.org/W2155083127","https://openalex.org/W2162537991","https://openalex.org/W2340885834","https://openalex.org/W2463249350","https://openalex.org/W3151244099","https://openalex.org/W4239945442","https://openalex.org/W4254125610","https://openalex.org/W6698124657"],"related_works":["https://openalex.org/W1530815982","https://openalex.org/W2210324350","https://openalex.org/W2035413309","https://openalex.org/W4206187654","https://openalex.org/W1606357879","https://openalex.org/W6097930","https://openalex.org/W2225478467","https://openalex.org/W1964603858","https://openalex.org/W2107388988","https://openalex.org/W95583346"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":12},{"year":2021,"cited_by_count":15},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":16},{"year":2017,"cited_by_count":14},{"year":2016,"cited_by_count":15},{"year":2015,"cited_by_count":15},{"year":2014,"cited_by_count":24},{"year":2013,"cited_by_count":20},{"year":2012,"cited_by_count":17}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}