{"id":"https://openalex.org/W2016266703","doi":"https://doi.org/10.1038/372055a0","title":"Mechanisms of intracellular protein transport","display_name":"Mechanisms of intracellular protein transport","publication_year":1994,"publication_date":"1994-11-01","ids":{"openalex":"https://openalex.org/W2016266703","doi":"https://doi.org/10.1038/372055a0","mag":"2016266703","pmid":"https://pubmed.ncbi.nlm.nih.gov/7969419"},"language":"en","primary_location":{"id":"doi:10.1038/372055a0","doi":"https://doi.org/10.1038/372055a0","is_oa":false,"landing_page_url":"https://doi.org/10.1038/372055a0","pdf_url":null,"source":{"id":"https://openalex.org/S137773608","display_name":"Nature","issn_l":"0028-0836","issn":["0028-0836","1476-4687"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5107942278","display_name":"James Edward Rothman","orcid":"https://orcid.org/0000-0003-4822-4161","observed_orcids":["https://orcid.org/0000-0003-4822-4161"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"James E. Rothman","raw_affiliation_strings":["Cellular Biochemistry and Biophysics Program, Memorial Sloan-Kettering Cancer Center, New York, New York 10021","Cellular Biochemistry & Biophysics Program, Memorial Sloan\u2010Kettering Cancer Center, New York, USA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cellular Biochemistry and Biophysics Program, Memorial Sloan-Kettering Cancer Center, New York, New York 10021","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"Cellular Biochemistry & Biophysics Program, Memorial Sloan\u2010Kettering Cancer Center, New York, USA;","institution_ids":["https://openalex.org/I1334819555"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5107942278"],"corresponding_institution_ids":["https://openalex.org/I1334819555"],"apc_list":{"value":12690,"currency":"USD","value_usd":12690},"apc_paid":null,"fwci":18.0559,"has_fulltext":false,"cited_by_count":2276,"citation_normalized_percentile":{"value":1.0,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"372","issue":"6501","first_page":"55","last_page":"63"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10773","display_name":"Extracellular vesicles in disease","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intracellular-protein-transport","display_name":"intracellular protein transport","score":0.9950000047683716},{"id":"https://openalex.org/keywords/vesicular-trafficking","display_name":"vesicle trafficking","score":0.5789999961853027},{"id":"https://openalex.org/keywords/secretion","display_name":"secretion","score":0.6579999923706055},{"id":"https://openalex.org/keywords/endocytosis","display_name":"endocytosis","score":1.0},{"id":"https://openalex.org/keywords/hormone-secretion","display_name":"hormone secretion","score":0.5059999823570251},{"id":"https://openalex.org/keywords/neurotransmitter-release","display_name":"neurotransmitter release","score":0.9890000224113464},{"id":"https://openalex.org/keywords/capsid-protein","display_name":"capsid protein","score":0.7419999837875366},{"id":"https://openalex.org/keywords/gtp-hydrolysis","display_name":"GTP hydrolysis","score":0.9729999899864197},{"id":"https://openalex.org/keywords/vesicle-docking","display_name":"vesicle docking","score":0.7609999775886536},{"id":"https://openalex.org/keywords/membrane-fusion","display_name":"membrane fusion","score":0.6949999928474426}],"concepts":[{"id":"https://openalex.org/C175969161","wikidata":"https://www.wikidata.org/wiki/Q323426","display_name":"Exocytosis","level":3,"score":0.8117475509643555},{"id":"https://openalex.org/C130316041","wikidata":"https://www.wikidata.org/wiki/Q189206","display_name":"Vesicle","level":3,"score":0.7471821904182434},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.705541729927063},{"id":"https://openalex.org/C28005876","wikidata":"https://www.wikidata.org/wiki/Q189814","display_name":"Endocytosis","level":3,"score":0.6499965786933899},{"id":"https://openalex.org/C49039625","wikidata":"https://www.wikidata.org/wiki/Q84230","display_name":"Secretion","level":2,"score":0.5875955820083618},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5746663212776184},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.546887993812561},{"id":"https://openalex.org/C57581600","wikidata":"https://www.wikidata.org/wiki/Q2449730","display_name":"Transport protein","level":2,"score":0.5387483835220337},{"id":"https://openalex.org/C118716","wikidata":"https://www.wikidata.org/wiki/Q5514725","display_name":"GTP'","level":3,"score":0.5315394401550293},{"id":"https://openalex.org/C190062978","wikidata":"https://www.wikidata.org/wiki/Q79899","display_name":"Cytoplasm","level":2,"score":0.5304989814758301},{"id":"https://openalex.org/C2780212709","wikidata":"https://www.wikidata.org/wiki/Q14890439","display_name":"Intracellular transport","level":3,"score":0.5243580341339111},{"id":"https://openalex.org/C2910636507","wikidata":"https://www.wikidata.org/wiki/Q4082043","display_name":"Vesicular Transport Proteins","level":5,"score":0.5220261216163635},{"id":"https://openalex.org/C167019083","wikidata":"https://www.wikidata.org/wiki/Q4082043","display_name":"Vesicular transport protein","level":4,"score":0.5085650682449341},{"id":"https://openalex.org/C41685203","wikidata":"https://www.wikidata.org/wiki/Q1974042","display_name":"Docking (animal)","level":2,"score":0.47496482729911804},{"id":"https://openalex.org/C102747710","wikidata":"https://www.wikidata.org/wiki/Q824237","display_name":"Endosome","level":3,"score":0.45803335309028625},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.44696685671806335},{"id":"https://openalex.org/C57947595","wikidata":"https://www.wikidata.org/wiki/Q7886088","display_name":"Membrane transport","level":3,"score":0.44520139694213867},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3732873201370239},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.33855515718460083},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3008565306663513},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.19931697845458984},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.15845251083374023},{"id":"https://openalex.org/C2777867350","wikidata":"https://www.wikidata.org/wiki/Q7908031","display_name":"Vacuolar protein sorting","level":4,"score":0.06312066316604614},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001692","descriptor_name":"Biological Transport","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005089","descriptor_name":"Exocytosis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006056","descriptor_name":"Golgi Apparatus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008561","descriptor_name":"Membrane Fusion","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015388","descriptor_name":"Organelles","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018699","descriptor_name":"Coated Vesicles","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1038/372055a0","doi":"https://doi.org/10.1038/372055a0","is_oa":false,"landing_page_url":"https://doi.org/10.1038/372055a0","pdf_url":null,"source":{"id":"https://openalex.org/S137773608","display_name":"Nature","issn_l":"0028-0836","issn":["0028-0836","1476-4687"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature","raw_type":"journal-article"},{"id":"pmid:7969419","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7969419","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":125,"referenced_works":["https://openalex.org/W91142790","https://openalex.org/W1481032119","https://openalex.org/W1504892441","https://openalex.org/W1509564548","https://openalex.org/W1516922966","https://openalex.org/W1535587662","https://openalex.org/W1536675102","https://openalex.org/W1541462376","https://openalex.org/W1572521445","https://openalex.org/W1577792223","https://openalex.org/W1580161657","https://openalex.org/W1592007354","https://openalex.org/W1659563560","https://openalex.org/W1942671396","https://openalex.org/W1964114871","https://openalex.org/W1965158583","https://openalex.org/W1965316807","https://openalex.org/W1970987547","https://openalex.org/W1971016259","https://openalex.org/W1976283234","https://openalex.org/W1976731691","https://openalex.org/W1980350621","https://openalex.org/W1981536301","https://openalex.org/W1984634392","https://openalex.org/W1984730682","https://openalex.org/W1985700603","https://openalex.org/W1986828137","https://openalex.org/W1988652098","https://openalex.org/W1990364715","https://openalex.org/W1991980875","https://openalex.org/W1993638185","https://openalex.org/W1995235301","https://openalex.org/W1995490800","https://openalex.org/W1995678301","https://openalex.org/W1997168691","https://openalex.org/W1997278714","https://openalex.org/W1998084411","https://openalex.org/W1999744850","https://openalex.org/W2001139514","https://openalex.org/W2004359271","https://openalex.org/W2005393972","https://openalex.org/W2005563114","https://openalex.org/W2006287134","https://openalex.org/W2008009726","https://openalex.org/W2008597859","https://openalex.org/W2009087844","https://openalex.org/W2009435363","https://openalex.org/W2013026243","https://openalex.org/W2013617213","https://openalex.org/W2015599928","https://openalex.org/W2016417523","https://openalex.org/W2017451004","https://openalex.org/W2017846437","https://openalex.org/W2017902030","https://openalex.org/W2018856829","https://openalex.org/W2019348717","https://openalex.org/W2020358132","https://openalex.org/W2021272662","https://openalex.org/W2022743955","https://openalex.org/W2026867728","https://openalex.org/W2029152767","https://openalex.org/W2030758635","https://openalex.org/W2030822379","https://openalex.org/W2033500343","https://openalex.org/W2034640855","https://openalex.org/W2035807916","https://openalex.org/W2037245313","https://openalex.org/W2038882113","https://openalex.org/W2039115958","https://openalex.org/W2040792888","https://openalex.org/W2042980484","https://openalex.org/W2043769210","https://openalex.org/W2048001750","https://openalex.org/W2048019766","https://openalex.org/W2048278170","https://openalex.org/W2049620445","https://openalex.org/W2050199375","https://openalex.org/W2052629714","https://openalex.org/W2054593368","https://openalex.org/W2056293200","https://openalex.org/W2056541157","https://openalex.org/W2057163724","https://openalex.org/W2059428912","https://openalex.org/W2059775037","https://openalex.org/W2062070852","https://openalex.org/W2062360693","https://openalex.org/W2064916160","https://openalex.org/W2065220292","https://openalex.org/W2065365365","https://openalex.org/W2066221480","https://openalex.org/W2071427211","https://openalex.org/W2071534681","https://openalex.org/W2073125666","https://openalex.org/W2077451533","https://openalex.org/W2078691152","https://openalex.org/W2079247381","https://openalex.org/W2079268511","https://openalex.org/W2083656092","https://openalex.org/W2085231991","https://openalex.org/W2085680244","https://openalex.org/W2088751119","https://openalex.org/W2089236772","https://openalex.org/W2090486711","https://openalex.org/W2092000023","https://openalex.org/W2094706331","https://openalex.org/W2094751799","https://openalex.org/W2100940618","https://openalex.org/W2103122002","https://openalex.org/W2106141363","https://openalex.org/W2114647945","https://openalex.org/W2120193545","https://openalex.org/W2124897859","https://openalex.org/W2130398497","https://openalex.org/W2138510980","https://openalex.org/W2144661465","https://openalex.org/W2145120474","https://openalex.org/W2147586746","https://openalex.org/W2152322252","https://openalex.org/W2153763976","https://openalex.org/W2163597027","https://openalex.org/W2167837958","https://openalex.org/W2172564477","https://openalex.org/W2415879570","https://openalex.org/W4211239492","https://openalex.org/W4241864365"],"related_works":["https://openalex.org/W2314544891","https://openalex.org/W1971590686","https://openalex.org/W1716621175","https://openalex.org/W1989164076","https://openalex.org/W2289078367","https://openalex.org/W1987925127","https://openalex.org/W122712717","https://openalex.org/W2053878745","https://openalex.org/W2083736779","https://openalex.org/W2277468878"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":19},{"year":2025,"cited_by_count":13},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":13},{"year":2022,"cited_by_count":18},{"year":2021,"cited_by_count":27},{"year":2020,"cited_by_count":21},{"year":2019,"cited_by_count":23},{"year":2018,"cited_by_count":22},{"year":2017,"cited_by_count":29},{"year":2016,"cited_by_count":26},{"year":2015,"cited_by_count":24},{"year":2014,"cited_by_count":39},{"year":2013,"cited_by_count":37},{"year":2012,"cited_by_count":39}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}
