{"id":"https://openalex.org/W2016239441","doi":"https://doi.org/10.1161/01.cir.100.20.2054","title":"Temporal Trends in Event Rates After Q-Wave Myocardial Infarction","display_name":"Temporal Trends in Event Rates After Q-Wave Myocardial Infarction","publication_year":1999,"publication_date":"1999-11-16","ids":{"openalex":"https://openalex.org/W2016239441","doi":"https://doi.org/10.1161/01.cir.100.20.2054","mag":"2016239441","pmid":"https://pubmed.ncbi.nlm.nih.gov/10562260"},"language":"en","primary_location":{"id":"doi:10.1161/01.cir.100.20.2054","doi":"https://doi.org/10.1161/01.cir.100.20.2054","is_oa":false,"landing_page_url":"https://doi.org/10.1161/01.cir.100.20.2054","pdf_url":null,"source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060615277","display_name":"Ursula C. Guidry","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210106489","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]},{"id":"https://openalex.org/I4210123017","display_name":"Framingham Heart Study","ror":"https://ror.org/031grv205","country_code":"US","type":"facility","lineage":["https://openalex.org/I111088046","https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489","https://openalex.org/I4210123017"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ursula C. Guidry","raw_affiliation_strings":["From the National Heart, Lung, and Blood Institute\u2019s Framingham Heart Study, Framingham, Mass (U.C.G., J.C.E., M.G.L., P.W.F.W., J.M.M., D.L.); National Heart, Lung, and Blood Institute, Bethesda, Md (P.W.F.W., D.L.); Sections of Preventive Medicine (U.C.G., J.C.E., M.G.L., J.M.M., D.L.) and General Internal Medicine (J.M.M.), Boston University School of Medicine, Boston, Mass; and the Divisions of Cardiology and Clinical Epidemiology, Beth Israel Hospital, Harvard Medical School, Boston, Mass (D.L.)","National Heart, Lung, and Blood Institute, Bethesda, Md (P.W.F.W., D.L.)","Sections of Preventive Medicine (U.C.G., J.C.E., M.G.L., J.M.M., D.L.) and General Internal Medicine (J.M.M.), Boston University School of Medicine, Boston, Mass","the Divisions of Cardiology and Clinical Epidemiology, Beth Israel Hospital, Harvard Medical School, Boston, Mass (D.L.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the National Heart, Lung, and Blood Institute\u2019s Framingham Heart Study, Framingham, Mass (U.C.G., J.C.E., M.G.L., P.W.F.W., J.M.M., D.L.); National Heart, Lung, and Blood Institute, Bethesda, Md (P.W.F.W., D.L.); Sections of Preventive Medicine (U.C.G., J.C.E., M.G.L., J.M.M., D.L.) and General Internal Medicine (J.M.M.), Boston University School of Medicine, Boston, Mass; and the Divisions of Cardiology and Clinical Epidemiology, Beth Israel Hospital, Harvard Medical School, Boston, Mass (D.L.)","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I4210106489","https://openalex.org/I4210123017"]},{"raw_affiliation_string":"National Heart, Lung, and Blood Institute, Bethesda, Md (P.W.F.W., D.L.)","institution_ids":["https://openalex.org/I4210106489"]},{"raw_affiliation_string":"Sections of Preventive Medicine (U.C.G., J.C.E., M.G.L., J.M.M., D.L.) and General Internal Medicine (J.M.M.), Boston University School of Medicine, Boston, Mass","institution_ids":["https://openalex.org/I111088046"]},{"raw_affiliation_string":"the Divisions of Cardiology and Clinical Epidemiology, Beth Israel Hospital, Harvard Medical School, Boston, Mass (D.L.)","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111607900","display_name":"Jane C. Evans","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210106489","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]},{"id":"https://openalex.org/I4210123017","display_name":"Framingham Heart Study","ror":"https://ror.org/031grv205","country_code":"US","type":"facility","lineage":["https://openalex.org/I111088046","https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489","https://openalex.org/I4210123017"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jane C. Evans","raw_affiliation_strings":["From the National Heart, Lung, and Blood Institute\u2019s Framingham Heart Study, Framingham, Mass (U.C.G., J.C.E., M.G.L., P.W.F.W., J.M.M., D.L.); National Heart, Lung, and Blood Institute, Bethesda, Md (P.W.F.W., D.L.); Sections of Preventive Medicine (U.C.G., J.C.E., M.G.L., J.M.M., D.L.) and General Internal Medicine (J.M.M.), Boston University School of Medicine, Boston, Mass; and the Divisions of Cardiology and Clinical Epidemiology, Beth Israel Hospital, Harvard Medical School, Boston, Mass (D.L.)","National Heart, Lung, and Blood Institute, Bethesda, Md (P.W.F.W., D.L.)","Sections of Preventive Medicine (U.C.G., J.C.E., M.G.L., J.M.M., D.L.) and General Internal Medicine (J.M.M.), Boston University School of Medicine, Boston, Mass","the Divisions of Cardiology and Clinical Epidemiology, Beth Israel Hospital, Harvard Medical School, Boston, Mass (D.L.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the National Heart, Lung, and Blood Institute\u2019s Framingham Heart Study, Framingham, Mass (U.C.G., J.C.E., M.G.L., P.W.F.W., J.M.M., D.L.); National Heart, Lung, and Blood Institute, Bethesda, Md (P.W.F.W., D.L.); Sections of Preventive Medicine (U.C.G., J.C.E., M.G.L., J.M.M., D.L.) and General Internal Medicine (J.M.M.), Boston University School of Medicine, Boston, Mass; and the Divisions of Cardiology and Clinical Epidemiology, Beth Israel Hospital, Harvard Medical School, Boston, Mass (D.L.)","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I4210106489","https://openalex.org/I4210123017"]},{"raw_affiliation_string":"National Heart, Lung, and Blood Institute, Bethesda, Md (P.W.F.W., D.L.)","institution_ids":["https://openalex.org/I4210106489"]},{"raw_affiliation_string":"Sections of Preventive Medicine (U.C.G., J.C.E., M.G.L., J.M.M., D.L.) and General Internal Medicine (J.M.M.), Boston University School of Medicine, Boston, Mass","institution_ids":["https://openalex.org/I111088046"]},{"raw_affiliation_string":"the Divisions of Cardiology and Clinical Epidemiology, Beth Israel Hospital, Harvard Medical School, Boston, Mass (D.L.)","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064623534","display_name":"Martin G. Larson","orcid":"https://orcid.org/0000-0002-9631-1254","observed_orcids":["https://orcid.org/0000-0002-9631-1254"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210106489","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]},{"id":"https://openalex.org/I4210123017","display_name":"Framingham Heart Study","ror":"https://ror.org/031grv205","country_code":"US","type":"facility","lineage":["https://openalex.org/I111088046","https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489","https://openalex.org/I4210123017"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Martin G. Larson","raw_affiliation_strings":["From the National Heart, Lung, and Blood Institute\u2019s Framingham Heart Study, Framingham, Mass (U.C.G., J.C.E., M.G.L., P.W.F.W., J.M.M., D.L.); National Heart, Lung, and Blood Institute, Bethesda, Md (P.W.F.W., D.L.); Sections of Preventive Medicine (U.C.G., J.C.E., M.G.L., J.M.M., D.L.) and General Internal Medicine (J.M.M.), Boston University School of Medicine, Boston, Mass; and the Divisions of Cardiology and Clinical Epidemiology, Beth Israel Hospital, Harvard Medical School, Boston, Mass (D.L.)","National Heart, Lung, and Blood Institute, Bethesda, Md (P.W.F.W., D.L.)","Sections of Preventive Medicine (U.C.G., J.C.E., M.G.L., J.M.M., D.L.) and General Internal Medicine (J.M.M.), Boston University School of Medicine, Boston, Mass","the Divisions of Cardiology and Clinical Epidemiology, Beth Israel Hospital, Harvard Medical School, Boston, Mass (D.L.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the National Heart, Lung, and Blood Institute\u2019s Framingham Heart Study, Framingham, Mass (U.C.G., J.C.E., M.G.L., P.W.F.W., J.M.M., D.L.); National Heart, Lung, and Blood Institute, Bethesda, Md (P.W.F.W., D.L.); Sections of Preventive Medicine (U.C.G., J.C.E., M.G.L., J.M.M., D.L.) and General Internal Medicine (J.M.M.), Boston University School of Medicine, Boston, Mass; and the Divisions of Cardiology and Clinical Epidemiology, Beth Israel Hospital, Harvard Medical School, Boston, Mass (D.L.)","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I4210106489","https://openalex.org/I4210123017"]},{"raw_affiliation_string":"National Heart, Lung, and Blood Institute, Bethesda, Md (P.W.F.W., D.L.)","institution_ids":["https://openalex.org/I4210106489"]},{"raw_affiliation_string":"Sections of Preventive Medicine (U.C.G., J.C.E., M.G.L., J.M.M., D.L.) and General Internal Medicine (J.M.M.), Boston University School of Medicine, Boston, Mass","institution_ids":["https://openalex.org/I111088046"]},{"raw_affiliation_string":"the Divisions of Cardiology and Clinical Epidemiology, Beth Israel Hospital, Harvard Medical School, Boston, Mass (D.L.)","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000776451","display_name":"Peter W.F. Wilson","orcid":"https://orcid.org/0000-0002-5653-7056","observed_orcids":["https://orcid.org/0000-0002-5653-7056"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210106489","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]},{"id":"https://openalex.org/I4210123017","display_name":"Framingham Heart Study","ror":"https://ror.org/031grv205","country_code":"US","type":"facility","lineage":["https://openalex.org/I111088046","https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489","https://openalex.org/I4210123017"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peter W. F. Wilson","raw_affiliation_strings":["From the National Heart, Lung, and Blood Institute\u2019s Framingham Heart Study, Framingham, Mass (U.C.G., J.C.E., M.G.L., P.W.F.W., J.M.M., D.L.); National Heart, Lung, and Blood Institute, Bethesda, Md (P.W.F.W., D.L.); Sections of Preventive Medicine (U.C.G., J.C.E., M.G.L., J.M.M., D.L.) and General Internal Medicine (J.M.M.), Boston University School of Medicine, Boston, Mass; and the Divisions of Cardiology and Clinical Epidemiology, Beth Israel Hospital, Harvard Medical School, Boston, Mass (D.L.)","National Heart, Lung, and Blood Institute, Bethesda, Md (P.W.F.W., D.L.)","Sections of Preventive Medicine (U.C.G., J.C.E., M.G.L., J.M.M., D.L.) and General Internal Medicine (J.M.M.), Boston University School of Medicine, Boston, Mass","the Divisions of Cardiology and Clinical Epidemiology, Beth Israel Hospital, Harvard Medical School, Boston, Mass (D.L.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the National Heart, Lung, and Blood Institute\u2019s Framingham Heart Study, Framingham, Mass (U.C.G., J.C.E., M.G.L., P.W.F.W., J.M.M., D.L.); National Heart, Lung, and Blood Institute, Bethesda, Md (P.W.F.W., D.L.); Sections of Preventive Medicine (U.C.G., J.C.E., M.G.L., J.M.M., D.L.) and General Internal Medicine (J.M.M.), Boston University School of Medicine, Boston, Mass; and the Divisions of Cardiology and Clinical Epidemiology, Beth Israel Hospital, Harvard Medical School, Boston, Mass (D.L.)","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I4210106489","https://openalex.org/I4210123017"]},{"raw_affiliation_string":"National Heart, Lung, and Blood Institute, Bethesda, Md (P.W.F.W., D.L.)","institution_ids":["https://openalex.org/I4210106489"]},{"raw_affiliation_string":"Sections of Preventive Medicine (U.C.G., J.C.E., M.G.L., J.M.M., D.L.) and General Internal Medicine (J.M.M.), Boston University School of Medicine, Boston, Mass","institution_ids":["https://openalex.org/I111088046"]},{"raw_affiliation_string":"the Divisions of Cardiology and Clinical Epidemiology, Beth Israel Hospital, Harvard Medical School, Boston, Mass (D.L.)","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038663858","display_name":"Joanne M. Murabito","orcid":"https://orcid.org/0000-0002-0192-7516","observed_orcids":["https://orcid.org/0000-0002-0192-7516"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210106489","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]},{"id":"https://openalex.org/I4210123017","display_name":"Framingham Heart Study","ror":"https://ror.org/031grv205","country_code":"US","type":"facility","lineage":["https://openalex.org/I111088046","https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489","https://openalex.org/I4210123017"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joanne M. Murabito","raw_affiliation_strings":["From the National Heart, Lung, and Blood Institute\u2019s Framingham Heart Study, Framingham, Mass (U.C.G., J.C.E., M.G.L., P.W.F.W., J.M.M., D.L.); National Heart, Lung, and Blood Institute, Bethesda, Md (P.W.F.W., D.L.); Sections of Preventive Medicine (U.C.G., J.C.E., M.G.L., J.M.M., D.L.) and General Internal Medicine (J.M.M.), Boston University School of Medicine, Boston, Mass; and the Divisions of Cardiology and Clinical Epidemiology, Beth Israel Hospital, Harvard Medical School, Boston, Mass (D.L.)","National Heart, Lung, and Blood Institute, Bethesda, Md (P.W.F.W., D.L.)","Sections of Preventive Medicine (U.C.G., J.C.E., M.G.L., J.M.M., D.L.) and General Internal Medicine (J.M.M.), Boston University School of Medicine, Boston, Mass","the Divisions of Cardiology and Clinical Epidemiology, Beth Israel Hospital, Harvard Medical School, Boston, Mass (D.L.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the National Heart, Lung, and Blood Institute\u2019s Framingham Heart Study, Framingham, Mass (U.C.G., J.C.E., M.G.L., P.W.F.W., J.M.M., D.L.); National Heart, Lung, and Blood Institute, Bethesda, Md (P.W.F.W., D.L.); Sections of Preventive Medicine (U.C.G., J.C.E., M.G.L., J.M.M., D.L.) and General Internal Medicine (J.M.M.), Boston University School of Medicine, Boston, Mass; and the Divisions of Cardiology and Clinical Epidemiology, Beth Israel Hospital, Harvard Medical School, Boston, Mass (D.L.)","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I4210106489","https://openalex.org/I4210123017"]},{"raw_affiliation_string":"National Heart, Lung, and Blood Institute, Bethesda, Md (P.W.F.W., D.L.)","institution_ids":["https://openalex.org/I4210106489"]},{"raw_affiliation_string":"Sections of Preventive Medicine (U.C.G., J.C.E., M.G.L., J.M.M., D.L.) and General Internal Medicine (J.M.M.), Boston University School of Medicine, Boston, Mass","institution_ids":["https://openalex.org/I111088046"]},{"raw_affiliation_string":"the Divisions of Cardiology and Clinical Epidemiology, Beth Israel Hospital, Harvard Medical School, Boston, Mass (D.L.)","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074117194","display_name":"Daniel A Levy","orcid":"https://orcid.org/0000-0003-1843-8724","observed_orcids":["https://orcid.org/0000-0003-1843-8724"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210106489","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]},{"id":"https://openalex.org/I4210123017","display_name":"Framingham Heart Study","ror":"https://ror.org/031grv205","country_code":"US","type":"facility","lineage":["https://openalex.org/I111088046","https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489","https://openalex.org/I4210123017"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel Levy","raw_affiliation_strings":["From the National Heart, Lung, and Blood Institute\u2019s Framingham Heart Study, Framingham, Mass (U.C.G., J.C.E., M.G.L., P.W.F.W., J.M.M., D.L.); National Heart, Lung, and Blood Institute, Bethesda, Md (P.W.F.W., D.L.); Sections of Preventive Medicine (U.C.G., J.C.E., M.G.L., J.M.M., D.L.) and General Internal Medicine (J.M.M.), Boston University School of Medicine, Boston, Mass; and the Divisions of Cardiology and Clinical Epidemiology, Beth Israel Hospital, Harvard Medical School, Boston, Mass (D.L.)","National Heart, Lung, and Blood Institute, Bethesda, Md (P.W.F.W., D.L.)","Sections of Preventive Medicine (U.C.G., J.C.E., M.G.L., J.M.M., D.L.) and General Internal Medicine (J.M.M.), Boston University School of Medicine, Boston, Mass","the Divisions of Cardiology and Clinical Epidemiology, Beth Israel Hospital, Harvard Medical School, Boston, Mass (D.L.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the National Heart, Lung, and Blood Institute\u2019s Framingham Heart Study, Framingham, Mass (U.C.G., J.C.E., M.G.L., P.W.F.W., J.M.M., D.L.); National Heart, Lung, and Blood Institute, Bethesda, Md (P.W.F.W., D.L.); Sections of Preventive Medicine (U.C.G., J.C.E., M.G.L., J.M.M., D.L.) and General Internal Medicine (J.M.M.), Boston University School of Medicine, Boston, Mass; and the Divisions of Cardiology and Clinical Epidemiology, Beth Israel Hospital, Harvard Medical School, Boston, Mass (D.L.)","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I4210106489","https://openalex.org/I4210123017"]},{"raw_affiliation_string":"National Heart, Lung, and Blood Institute, Bethesda, Md (P.W.F.W., D.L.)","institution_ids":["https://openalex.org/I4210106489"]},{"raw_affiliation_string":"Sections of Preventive Medicine (U.C.G., J.C.E., M.G.L., J.M.M., D.L.) and General Internal Medicine (J.M.M.), Boston University School of Medicine, Boston, Mass","institution_ids":["https://openalex.org/I111088046"]},{"raw_affiliation_string":"the Divisions of Cardiology and Clinical Epidemiology, Beth Israel Hospital, Harvard Medical School, Boston, Mass (D.L.)","institution_ids":["https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.6653,"has_fulltext":false,"cited_by_count":124,"citation_normalized_percentile":{"value":0.9039025,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"100","issue":"20","first_page":"2054","last_page":"2059"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10292","display_name":"Acute Myocardial Infarction Research","score":0.9848999977111816,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10292","display_name":"Acute Myocardial Infarction Research","score":0.9848999977111816,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11083","display_name":"Cardiac Health and Mental Health","score":0.006000000052154064,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12935","display_name":"Healthcare Systems and Public Health","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/q-wave-myocardial-infarction","display_name":"Q-wave myocardial infarction","score":0.9980000257492065},{"id":"https://openalex.org/keywords/temporal-trends","display_name":"temporal trends","score":0.9269999861717224},{"id":"https://openalex.org/keywords/coronary-heart-disease-mortality","display_name":"coronary heart disease mortality","score":0.9020000100135803},{"id":"https://openalex.org/keywords/all-cause-mortality","display_name":"all-cause mortality","score":0.9990000128746033},{"id":"https://openalex.org/keywords/recurrent-myocardial-infarction","display_name":"reinfarction","score":0.9430000185966492},{"id":"https://openalex.org/keywords/congestive-heart-failure","display_name":"congestive heart failure","score":0.9990000128746033},{"id":"https://openalex.org/keywords/left-ventricular-systolic-function","display_name":"left ventricular systolic function","score":0.8309999704360962},{"id":"https://openalex.org/keywords/framingham-heart-study","display_name":"Framingham Heart Study","score":0.9279999732971191}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.950444757938385},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.773383378982544},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.6808597445487976},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6616297960281372},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6181316375732422},{"id":"https://openalex.org/C111815664","wikidata":"https://www.wikidata.org/wiki/Q1440693","display_name":"Framingham Heart Study","level":4,"score":0.5889789462089539},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.5436945557594299},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.4203191101551056},{"id":"https://openalex.org/C11783203","wikidata":"https://www.wikidata.org/wiki/Q5478027","display_name":"Framingham Risk Score","level":3,"score":0.32787466049194336},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.27154475450515747},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004562","descriptor_name":"Electrocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1161/01.cir.100.20.2054","doi":"https://doi.org/10.1161/01.cir.100.20.2054","is_oa":false,"landing_page_url":"https://doi.org/10.1161/01.cir.100.20.2054","pdf_url":null,"source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation","raw_type":"journal-article"},{"id":"pmid:10562260","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10562260","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation","raw_type":"Clinical Trial"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.8799999952316284,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1899027764","display_name":"Sleep Heart Health Study","funder_award_id":"U01HL053941","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G2340333184","display_name":"PHYSICAL EXAMINATION/TESTING THE FRAMINGHAM OFFSPRING","funder_award_id":"n01hc038038-022","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3524360209","display_name":null,"funder_award_id":"U01 HL 53941","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G454902129","display_name":null,"funder_award_id":"N01-HC-38038","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W1520185814","https://openalex.org/W2001180249","https://openalex.org/W2008827772","https://openalex.org/W2010402677","https://openalex.org/W2011819931","https://openalex.org/W2034566127","https://openalex.org/W2037510063","https://openalex.org/W2064355680","https://openalex.org/W2065039512","https://openalex.org/W2075788673","https://openalex.org/W2079033481","https://openalex.org/W2083384274","https://openalex.org/W2086142234","https://openalex.org/W2102055267","https://openalex.org/W2129624996","https://openalex.org/W2137253991","https://openalex.org/W2166776142","https://openalex.org/W2211287272","https://openalex.org/W2323862874","https://openalex.org/W2329306090","https://openalex.org/W2332619349","https://openalex.org/W2336123839","https://openalex.org/W3147894994","https://openalex.org/W4249271663","https://openalex.org/W4253094109","https://openalex.org/W4255785006","https://openalex.org/W4285719527","https://openalex.org/W4300718753"],"related_works":["https://openalex.org/W2105872403","https://openalex.org/W2046070496","https://openalex.org/W2125112109","https://openalex.org/W4239801596","https://openalex.org/W2247566428","https://openalex.org/W2007357695","https://openalex.org/W2033476435","https://openalex.org/W7101073349","https://openalex.org/W2021450829","https://openalex.org/W4381599178"],"abstract_inverted_index":{"BACKGROUND:":[0],"Short-term":[1],"(<30":[2],"day)":[3],"mortality":[4,80,162,209],"after":[5,24],"Q-wave":[6,25,60],"myocardial":[7],"infarction":[8],"(MI)":[9],"has":[10],"declined":[11,164],"over":[12,211],"the":[13,95,107,114,125,131,192],"decades,":[14,214],"but":[15],"it":[16],"is":[17],"unclear":[18],"if":[19],"rates":[20],"of":[21,44,53,204,223,236],"long-term":[22],"sequelae":[23],"MI":[26,61,196],"have":[27],"improved.":[28],"METHODS":[29],"AND":[30],"RESULTS:":[31],"In":[32],"546":[33],"Framingham":[34],"Heart":[35],"Study":[36],"subjects":[37],"(388":[38],"men":[39],"with":[40,49,56,124,216,238],"a":[41,50,224],"mean":[42,51],"age":[43,52],"60":[45],"years;":[46],"158":[47],"women":[48],"69":[54],"years)":[55],"an":[57],"initial":[58],"recognized":[59],"from":[62],"1950":[63,91,126],"through":[64,92,127,142,152,166,176],"1989,":[65],"we":[66],"investigated":[67],"time":[68,116],"trends":[69],"in":[70,138,191,202,218,226],"risk":[71,203,248],"for":[72,101,106,120,133,194,249],"coronary":[73],"heart":[74,86],"disease":[75],"(CHD)":[76],"death":[77,135,206],"(n=199),":[78],"all-cause":[79,208],"(n=287),":[81],"reinfarction":[82],"(n=108),":[83],"and":[84,109,207],"congestive":[85],"failure":[87],"(CHF;":[88],"n=121).":[89],"With":[90],"1969":[93,128],"as":[94],"reference":[96,129],"period,":[97,130],"hazards":[98],"ratios":[99],"(HRs)":[100],"these":[102,212],"outcomes":[103],"were":[104,118,136,186],"determined":[105],"1970s":[108],"1980s.":[110],"Trend":[111],"analyses":[112],"across":[113],"3":[115],"periods":[117],"performed":[119],"each":[121],"outcome.":[122],"Compared":[123],"HRs":[132],"CHD":[134,205],"lower":[137],"subsequent":[139],"decades":[140],"(1970":[141,165],"1979:":[143,167],"HR,":[144,154,168,178],"0.69;":[145],"95%":[146,156,170,180],"CI,":[147,157,171,181],"0.49":[148],"to":[149,159,173,183,232],"0.98;":[150],"1980":[151,175],"1989:":[153,177],"0.48;":[155],"0.33":[158],"0.72).":[160],"All-cause":[161],"also":[163],"0.70;":[169],"0.0.52":[172],"0.94;":[174],"0.59;":[179],"0.43":[182],"0.81).":[184],"There":[185],"no":[187],"significant":[188],"temporal":[189],"changes":[190],"risks":[193],"recurrent":[195],"or":[197],"CHF.":[198,250],"CONCLUSIONS:":[199],"Substantial":[200],"reductions":[201],"occurred":[210],"4":[213],"coincident":[215],"improvements":[217],"post-MI":[219,234],"therapies.":[220],"The":[221],"absence":[222],"decline":[225],"CHF":[227],"incidence":[228],"may":[229],"be":[230],"due":[231],"improved":[233],"survival":[235],"individuals":[237],"depressed":[239],"left":[240],"ventricular":[241],"systolic":[242],"function":[243],"who":[244],"are":[245],"at":[246],"high":[247]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":3},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
