{"id":"https://openalex.org/W2016207417","doi":"https://doi.org/10.1007/bf03347998","title":"Long-term effects of octreotide on markers of bone metabolism in acromegaly: Evidence of increased serum parathormone concentrations","display_name":"Long-term effects of octreotide on markers of bone metabolism in acromegaly: Evidence of increased serum parathormone concentrations","publication_year":1997,"publication_date":"1997-09-01","ids":{"openalex":"https://openalex.org/W2016207417","doi":"https://doi.org/10.1007/bf03347998","mag":"2016207417","pmid":"https://pubmed.ncbi.nlm.nih.gov/9364245"},"language":"en","primary_location":{"id":"doi:10.1007/bf03347998","doi":"https://doi.org/10.1007/bf03347998","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf03347998","pdf_url":null,"source":{"id":"https://openalex.org/S207799248","display_name":"Journal of Endocrinological Investigation","issn_l":"0391-4097","issn":["0391-4097","1720-8386"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Endocrinological Investigation","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047356105","display_name":"Pietro Legovini","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Pietro Legovini","raw_affiliation_strings":["Divisione Medica, Ospedale Regionale, Treviso, Italy","Ospedale Regionale"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Divisione Medica, Ospedale Regionale, Treviso, Italy","institution_ids":[]},{"raw_affiliation_string":"Ospedale Regionale","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024761566","display_name":"Ernesto De Menis","orcid":"https://orcid.org/0009-0009-6043-3725","observed_orcids":["https://orcid.org/0009-0009-6043-3725"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E. De Menis","raw_affiliation_strings":["I Divisione Medica, Ospedale Regionale, 31100, Treviso, Italy","Ospedale Regionale"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"I Divisione Medica, Ospedale Regionale, 31100, Treviso, Italy","institution_ids":[]},{"raw_affiliation_string":"Ospedale Regionale","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065517253","display_name":"Fulvio Breda","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F. Breda","raw_affiliation_strings":["I Divisione Medica, Ospedale Regionale, 31100, Treviso, Italy","Ospedale Regionale"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"I Divisione Medica, Ospedale Regionale, 31100, Treviso, Italy","institution_ids":[]},{"raw_affiliation_string":"Ospedale Regionale","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077435253","display_name":"Domenico Billeci","orcid":"https://orcid.org/0000-0002-3218-6685","observed_orcids":["https://orcid.org/0000-0002-3218-6685"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D. Billeci","raw_affiliation_strings":["Divisione di Neurochirurgia, Ospedale Regionale, Treviso, Italy","Ospedale Regionale"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Divisione di Neurochirurgia, Ospedale Regionale, Treviso, Italy","institution_ids":[]},{"raw_affiliation_string":"Ospedale Regionale","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089922878","display_name":"Alessandro Carteri","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A. Carteri","raw_affiliation_strings":["Divisione di Neurochirurgia, Ospedale Regionale, Treviso, Italy","Ospedale Regionale"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Divisione di Neurochirurgia, Ospedale Regionale, Treviso, Italy","institution_ids":[]},{"raw_affiliation_string":"Ospedale Regionale","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113933948","display_name":"P. Pavan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P. Pavan","raw_affiliation_strings":["I Divisione Medica, Ospedale Regionale, 31100, Treviso, Italy","Ospedale Regionale"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"I Divisione Medica, Ospedale Regionale, 31100, Treviso, Italy","institution_ids":[]},{"raw_affiliation_string":"Ospedale Regionale","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5018930166","display_name":"Nicola Conte","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N. Conte","raw_affiliation_strings":["I Divisione Medica, Ospedale Regionale, 31100, Treviso, Italy","Ospedale Regionale"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"I Divisione Medica, Ospedale Regionale, 31100, Treviso, Italy","institution_ids":[]},{"raw_affiliation_string":"Ospedale Regionale","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4790,"currency":"USD","value_usd":4790},"apc_paid":null,"fwci":0.6387,"has_fulltext":false,"cited_by_count":37,"citation_normalized_percentile":{"value":0.66691952,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"20","issue":"8","first_page":"434","last_page":"438"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10832","display_name":"Pituitary Gland Disorders and Treatments","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10832","display_name":"Pituitary Gland Disorders and Treatments","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10748","display_name":"Growth Hormone and Insulin-like Growth Factors","score":0.002300000051036477,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/octreotide","display_name":"octreotide","score":0.9929999709129333},{"id":"https://openalex.org/keywords/acromegaly","display_name":"acromegaly","score":0.9990000128746033},{"id":"https://openalex.org/keywords/bone-metabolism","display_name":"bone metabolism","score":0.7020000219345093},{"id":"https://openalex.org/keywords/parathyroid-hormone","display_name":"parathyroid hormone","score":0.8930000066757202},{"id":"https://openalex.org/keywords/secondary-hyperparathyroidism","display_name":"secondary hyperparathyroidism","score":0.9789999723434448},{"id":"https://openalex.org/keywords/calcium-homeostasis","display_name":"calcium homeostasis","score":0.8429999947547913},{"id":"https://openalex.org/keywords/bone-turnover-markers","display_name":"bone turnover markers","score":0.7929999828338623},{"id":"https://openalex.org/keywords/osteocalcin","display_name":"osteocalcin","score":0.8510000109672546},{"id":"https://openalex.org/keywords/alkaline-phosphatase","display_name":"alkaline phosphatase","score":0.9940000176429749},{"id":"https://openalex.org/keywords/urinary-calcium-excretion","display_name":"urinary calcium excretion","score":0.6850000023841858},{"id":"https://openalex.org/keywords/growth-hormone","display_name":"growth hormone","score":0.8040000200271606},{"id":"https://openalex.org/keywords/insulin-like-growth-factor-i","display_name":"insulin-like growth factor I","score":0.9369999766349792},{"id":"https://openalex.org/keywords/long-term-treatment","display_name":"long-term treatment","score":0.6850000023841858}],"concepts":[{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.8544923067092896},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.8431977033615112},{"id":"https://openalex.org/C2781025020","wikidata":"https://www.wikidata.org/wiki/Q419935","display_name":"Octreotide","level":3,"score":0.7625371813774109},{"id":"https://openalex.org/C2777433750","wikidata":"https://www.wikidata.org/wiki/Q189580","display_name":"Acromegaly","level":4,"score":0.685204029083252},{"id":"https://openalex.org/C170033053","wikidata":"https://www.wikidata.org/wiki/Q952019","display_name":"Bone remodeling","level":2,"score":0.6536149978637695},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.589659571647644},{"id":"https://openalex.org/C2779797417","wikidata":"https://www.wikidata.org/wiki/Q12460151","display_name":"Hydroxyproline","level":2,"score":0.5871409177780151},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.487719863653183},{"id":"https://openalex.org/C10146269","wikidata":"https://www.wikidata.org/wiki/Q185557","display_name":"Excretion","level":2,"score":0.48022136092185974},{"id":"https://openalex.org/C2780439177","wikidata":"https://www.wikidata.org/wiki/Q1442923","display_name":"Malabsorption","level":2,"score":0.47639575600624084},{"id":"https://openalex.org/C131075544","wikidata":"https://www.wikidata.org/wiki/Q415863","display_name":"Osteocalcin","level":4,"score":0.4620816707611084},{"id":"https://openalex.org/C160160445","wikidata":"https://www.wikidata.org/wiki/Q24769688","display_name":"Alkaline phosphatase","level":3,"score":0.432783842086792},{"id":"https://openalex.org/C2779053571","wikidata":"https://www.wikidata.org/wiki/Q2919083","display_name":"Primary hyperparathyroidism","level":2,"score":0.42991313338279724},{"id":"https://openalex.org/C87975464","wikidata":"https://www.wikidata.org/wiki/Q910704","display_name":"Calcium metabolism","level":3,"score":0.4274753928184509},{"id":"https://openalex.org/C2776697488","wikidata":"https://www.wikidata.org/wiki/Q4210589","display_name":"Urinary calcium","level":3,"score":0.42690667510032654},{"id":"https://openalex.org/C77411442","wikidata":"https://www.wikidata.org/wiki/Q181100","display_name":"Urinary system","level":2,"score":0.4234279990196228},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2303856611251831},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.21171492338180542},{"id":"https://openalex.org/C2776297358","wikidata":"https://www.wikidata.org/wiki/Q407166","display_name":"Somatostatin","level":2,"score":0.1403627097606659},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C2984496839","wikidata":"https://www.wikidata.org/wiki/Q29956617","display_name":"Growth hormone","level":3,"score":0.0},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000172","descriptor_name":"Acromegaly","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000172","descriptor_name":"Acromegaly","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001842","descriptor_name":"Bone and Bones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006728","descriptor_name":"Hormones","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007334","descriptor_name":"Insulin-Like Growth Factor I","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010281","descriptor_name":"Parathyroid Hormone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D013006","descriptor_name":"Growth Hormone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D013268","descriptor_name":"Stimulation, Chemical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015282","descriptor_name":"Octreotide","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/bf03347998","doi":"https://doi.org/10.1007/bf03347998","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf03347998","pdf_url":null,"source":{"id":"https://openalex.org/S207799248","display_name":"Journal of Endocrinological Investigation","issn_l":"0391-4097","issn":["0391-4097","1720-8386"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Endocrinological Investigation","raw_type":"journal-article"},{"id":"pmid:9364245","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9364245","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of endocrinological investigation","raw_type":"Clinical Trial"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W1965682284","https://openalex.org/W1970628361","https://openalex.org/W1976124550","https://openalex.org/W1985356497","https://openalex.org/W1990967695","https://openalex.org/W1991147882","https://openalex.org/W1993043688","https://openalex.org/W1995248103","https://openalex.org/W1996551329","https://openalex.org/W1998644272","https://openalex.org/W2005231636","https://openalex.org/W2016519769","https://openalex.org/W2017822774","https://openalex.org/W2030951215","https://openalex.org/W2031410788","https://openalex.org/W2032111961","https://openalex.org/W2037108457","https://openalex.org/W2047613985","https://openalex.org/W2052808852","https://openalex.org/W2071370534","https://openalex.org/W2092179662","https://openalex.org/W2092388988","https://openalex.org/W2108368848","https://openalex.org/W2145708538","https://openalex.org/W2167310208","https://openalex.org/W2171007668"],"related_works":["https://openalex.org/W1965682284","https://openalex.org/W2167310208","https://openalex.org/W1965913464","https://openalex.org/W2055387433","https://openalex.org/W1995248103","https://openalex.org/W2077140119","https://openalex.org/W2065807958","https://openalex.org/W1986534518","https://openalex.org/W2076991536","https://openalex.org/W2145509053"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}