{"id":"https://openalex.org/W2016194811","doi":"https://doi.org/10.1016/0012-1606(71)90096-0","title":"Protein synthesis and development in the absence of cytoplasmic RNA synthesis in nonnucleate egg fragments and embryos of sea urchins: Effect of ethidium bromide","display_name":"Protein synthesis and development in the absence of cytoplasmic RNA synthesis in nonnucleate egg fragments and embryos of sea urchins: Effect of ethidium bromide","publication_year":1971,"publication_date":"1971-02-01","ids":{"openalex":"https://openalex.org/W2016194811","doi":"https://doi.org/10.1016/0012-1606(71)90096-0","mag":"2016194811","pmid":"https://pubmed.ncbi.nlm.nih.gov/5103257"},"language":"en","primary_location":{"id":"doi:10.1016/0012-1606(71)90096-0","doi":"https://doi.org/10.1016/0012-1606(71)90096-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0012-1606(71)90096-0","pdf_url":null,"source":{"id":"https://openalex.org/S136634221","display_name":"Developmental Biology","issn_l":"0012-1606","issn":["0012-1606","1095-564X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073525159","display_name":"Sydney P. Craig","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I122411786","display_name":"California Institute of Technology","ror":"https://ror.org/05dxps055","country_code":"US","type":"education","lineage":["https://openalex.org/I122411786"]},{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sydney P. Craig","raw_affiliation_strings":["Division of Biology, California Institute of Technology, Pasadena, California USA","National Institute of Child Health and Human Development, Bethesda, Maryland 20014, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Biology, California Institute of Technology, Pasadena, California USA","institution_ids":["https://openalex.org/I122411786"]},{"raw_affiliation_string":"National Institute of Child Health and Human Development, Bethesda, Maryland 20014, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5067297656","display_name":"Joram Piatigorsky","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I122411786","display_name":"California Institute of Technology","ror":"https://ror.org/05dxps055","country_code":"US","type":"education","lineage":["https://openalex.org/I122411786"]},{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Joram Piatigorsky","raw_affiliation_strings":["Division of Biology, California Institute of Technology, Pasadena, California USA","National Institute of Child Health and Human Development, Bethesda, Maryland 20014, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Biology, California Institute of Technology, Pasadena, California USA","institution_ids":["https://openalex.org/I122411786"]},{"raw_affiliation_string":"National Institute of Child Health and Human Development, Bethesda, Maryland 20014, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5067297656"],"corresponding_institution_ids":["https://openalex.org/I122411786","https://openalex.org/I1299303238","https://openalex.org/I4210144228"],"apc_list":{"value":3550,"currency":"USD","value_usd":3550},"apc_paid":null,"fwci":2.9357,"has_fulltext":false,"cited_by_count":42,"citation_normalized_percentile":{"value":0.90887615,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"24","issue":"2","first_page":"214","last_page":"232"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.6942999958992004,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.6942999958992004,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.24169999361038208,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.01810000091791153,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ethidium-bromide","display_name":"ethidium bromide","score":0.8190000057220459},{"id":"https://openalex.org/keywords/rna-dependent-protein-synthesis","display_name":"RNA-dependent protein synthesis","score":0.6539999842643738},{"id":"https://openalex.org/keywords/sea-urchin-embryo","display_name":"sea urchin embryo","score":0.7390000224113464},{"id":"https://openalex.org/keywords/strongylocentrotus-purpuratus","display_name":"Strongylocentrotus purpuratus","score":0.9950000047683716},{"id":"https://openalex.org/keywords/embryonic-development","display_name":"embryonic development","score":0.5989999771118164},{"id":"https://openalex.org/keywords/dactinomycin","display_name":"actinomycin D","score":0.8960000276565552},{"id":"https://openalex.org/keywords/uridine-incorporation","display_name":"uridine incorporation","score":0.7160000205039978},{"id":"https://openalex.org/keywords/blastula","display_name":"blastula","score":0.4959999918937683},{"id":"https://openalex.org/keywords/mesenchyme","display_name":"mesenchyme","score":0.6510000228881836},{"id":"https://openalex.org/keywords/gastrula","display_name":"gastrula","score":0.7289999723434448},{"id":"https://openalex.org/keywords/larval-development","display_name":"larval development","score":0.5960000157356262},{"id":"https://openalex.org/keywords/developmental-arrest","display_name":"developmental arrest","score":0.5070000290870667}],"concepts":[{"id":"https://openalex.org/C2776907736","wikidata":"https://www.wikidata.org/wiki/Q408634","display_name":"Ethidium bromide","level":3,"score":0.9652840495109558},{"id":"https://openalex.org/C6047887","wikidata":"https://www.wikidata.org/wiki/Q420811","display_name":"Blastula","level":5,"score":0.8847450017929077},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7879404425621033},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.6127813458442688},{"id":"https://openalex.org/C2777569064","wikidata":"https://www.wikidata.org/wiki/Q1936405","display_name":"Strongylocentrotus purpuratus","level":3,"score":0.5813437104225159},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.5708166360855103},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5628594160079956},{"id":"https://openalex.org/C2781259782","wikidata":"https://www.wikidata.org/wiki/Q422573","display_name":"Uridine","level":4,"score":0.50307697057724},{"id":"https://openalex.org/C3675279","wikidata":"https://www.wikidata.org/wiki/Q211935","display_name":"Protein biosynthesis","level":2,"score":0.428845077753067},{"id":"https://openalex.org/C116084860","wikidata":"https://www.wikidata.org/wiki/Q48255","display_name":"Gel electrophoresis","level":2,"score":0.4254572093486786},{"id":"https://openalex.org/C87073359","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryogenesis","level":3,"score":0.27757585048675537},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.25104403495788574},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09018918871879578},{"id":"https://openalex.org/C129536746","wikidata":"https://www.wikidata.org/wiki/Q1141026","display_name":"Gastrulation","level":4,"score":0.0}],"mesh":[{"descriptor_ui":"D000890","descriptor_name":"Anti-Infective Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D002499","descriptor_name":"Centrifugation, Density Gradient","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003609","descriptor_name":"Dactinomycin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004447","descriptor_name":"Echinodermata","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":true},{"descriptor_ui":"D004589","descriptor_name":"Electrophoresis, Disc","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010063","descriptor_name":"Ovum","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D010063","descriptor_name":"Ovum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D013698","descriptor_name":"Templates, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014176","descriptor_name":"Protein Biosynthesis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014316","descriptor_name":"Tritium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014529","descriptor_name":"Uridine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014633","descriptor_name":"Valine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0012-1606(71)90096-0","doi":"https://doi.org/10.1016/0012-1606(71)90096-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0012-1606(71)90096-0","pdf_url":null,"source":{"id":"https://openalex.org/S136634221","display_name":"Developmental Biology","issn_l":"0012-1606","issn":["0012-1606","1095-564X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental Biology","raw_type":"journal-article"},{"id":"pmid:5103257","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/5103257","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental biology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"score":0.8999999761581421,"id":"https://metadata.un.org/sdg/14","display_name":"Life below water"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":51,"referenced_works":["https://openalex.org/W647318957","https://openalex.org/W1587674444","https://openalex.org/W1956793061","https://openalex.org/W1966056582","https://openalex.org/W1966532367","https://openalex.org/W1968434470","https://openalex.org/W1975107163","https://openalex.org/W1985235286","https://openalex.org/W1987654848","https://openalex.org/W1988762801","https://openalex.org/W1991645668","https://openalex.org/W1991784541","https://openalex.org/W1995004462","https://openalex.org/W1996456459","https://openalex.org/W2002199422","https://openalex.org/W2003152735","https://openalex.org/W2009397253","https://openalex.org/W2010103763","https://openalex.org/W2013762004","https://openalex.org/W2018900997","https://openalex.org/W2021504472","https://openalex.org/W2022368654","https://openalex.org/W2025529090","https://openalex.org/W2025989516","https://openalex.org/W2039152952","https://openalex.org/W2045759361","https://openalex.org/W2054360302","https://openalex.org/W2058033389","https://openalex.org/W2058157521","https://openalex.org/W2059048788","https://openalex.org/W2059187032","https://openalex.org/W2061033588","https://openalex.org/W2061921824","https://openalex.org/W2062763216","https://openalex.org/W2065627978","https://openalex.org/W2066353663","https://openalex.org/W2067831996","https://openalex.org/W2068360612","https://openalex.org/W2069757749","https://openalex.org/W2074889889","https://openalex.org/W2080227993","https://openalex.org/W2086659612","https://openalex.org/W2089557229","https://openalex.org/W2091901891","https://openalex.org/W2132481027","https://openalex.org/W2242293214","https://openalex.org/W2601913882","https://openalex.org/W2739818277","https://openalex.org/W4214824787","https://openalex.org/W4246562104","https://openalex.org/W7064213390"],"related_works":["https://openalex.org/W2130869769","https://openalex.org/W147911405","https://openalex.org/W2010103763","https://openalex.org/W1988762801","https://openalex.org/W2009397253","https://openalex.org/W1587674444","https://openalex.org/W2047331994","https://openalex.org/W1956793061","https://openalex.org/W2048366659","https://openalex.org/W2054360302"],"abstract_inverted_index":null,"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2014,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}