{"id":"https://openalex.org/W2016121778","doi":"https://doi.org/10.1016/j.jad.2014.12.033","title":"IL-23 and TGF-\u03b21 levels as potential predictive biomarkers in treatment of bipolar I disorder with acute manic episode","display_name":"IL-23 and TGF-\u03b21 levels as potential predictive biomarkers in treatment of bipolar I disorder with acute manic episode","publication_year":2014,"publication_date":"2014-12-19","ids":{"openalex":"https://openalex.org/W2016121778","doi":"https://doi.org/10.1016/j.jad.2014.12.033","mag":"2016121778","pmid":"https://pubmed.ncbi.nlm.nih.gov/25545602"},"language":"en","primary_location":{"id":"doi:10.1016/j.jad.2014.12.033","doi":"https://doi.org/10.1016/j.jad.2014.12.033","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jad.2014.12.033","pdf_url":null,"source":{"id":"https://openalex.org/S113871862","display_name":"Journal of Affective Disorders","issn_l":"0165-0327","issn":["0165-0327","1573-2517"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Affective Disorders","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008891245","display_name":"Haozhe Li","orcid":"https://orcid.org/0000-0003-1588-1384","observed_orcids":["https://orcid.org/0000-0003-1588-1384","https://orcid.org/0009-0009-2554-3013"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2802690428","display_name":"Shanghai Mental Health Center","ror":"https://ror.org/05bd2wa15","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802690428"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haozhe Li","raw_affiliation_strings":["Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong, University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong, University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2802690428"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108009090","display_name":"Wu Hong","orcid":"https://orcid.org/0000-0001-9980-2481","observed_orcids":["https://orcid.org/0000-0001-9980-2481"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2802690428","display_name":"Shanghai Mental Health Center","ror":"https://ror.org/05bd2wa15","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802690428"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wu Hong","raw_affiliation_strings":["Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: drhongwu@126.com","Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong, University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: drhongwu@126.com","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2802690428"]},{"raw_affiliation_string":"Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong, University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2802690428"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100374187","display_name":"Chen Zhang","orcid":"https://orcid.org/0000-0003-4071-1627","observed_orcids":["https://orcid.org/0000-0003-4071-1627"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2802690428","display_name":"Shanghai Mental Health Center","ror":"https://ror.org/05bd2wa15","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802690428"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chen Zhang","raw_affiliation_strings":["Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong, University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong, University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2802690428"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044911120","display_name":"Zhiguo Wu","orcid":"https://orcid.org/0000-0002-5877-2631","observed_orcids":["https://orcid.org/0000-0002-5877-2631"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2802690428","display_name":"Shanghai Mental Health Center","ror":"https://ror.org/05bd2wa15","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802690428"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhiguo Wu","raw_affiliation_strings":["Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong, University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong, University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2802690428"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105972186","display_name":"Zuowei Wang","orcid":"https://orcid.org/0000-0002-1929-231X","observed_orcids":["https://orcid.org/0000-0002-1929-231X"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2802690428","display_name":"Shanghai Mental Health Center","ror":"https://ror.org/05bd2wa15","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802690428"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zuowei Wang","raw_affiliation_strings":["Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Division of Mood Disorders, Hongkou District Mental Health Center, Shanghai, China","Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Division of Mood Disorders, Hongkou District Mental Health Center, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2802690428"]},{"raw_affiliation_string":"Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2802690428"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056245027","display_name":"Chenmei Yuan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2802690428","display_name":"Shanghai Mental Health Center","ror":"https://ror.org/05bd2wa15","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802690428"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chenmei Yuan","raw_affiliation_strings":["Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong, University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong, University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2802690428"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002920886","display_name":"Zezhi Li","orcid":"https://orcid.org/0000-0003-0241-1500","observed_orcids":["https://orcid.org/0000-0003-0241-1500","https://orcid.org/0000-0001-9149-5800"]},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]},{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2802690428","display_name":"Shanghai Mental Health Center","ror":"https://ror.org/05bd2wa15","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802690428"]},{"id":"https://openalex.org/I4210115928","display_name":"Changhai Hospital","ror":"https://ror.org/02bjs0p66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210115928"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zezhi Li","raw_affiliation_strings":["Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Department of Neurology, Shanghai Changhai Hospital, Secondary Military Medical University, Shanghai, China","Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Department of Neurology, Shanghai Changhai Hospital, Secondary Military Medical University, Shanghai, China","institution_ids":["https://openalex.org/I177933477","https://openalex.org/I183067930","https://openalex.org/I2802690428","https://openalex.org/I4210115928"]},{"raw_affiliation_string":"Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2802690428"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112486362","display_name":"Jia Huang","orcid":"https://orcid.org/0000-0001-7269-6797","observed_orcids":["https://orcid.org/0000-0001-7269-6797","https://orcid.org/0000-0001-5370-3509"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2802690428","display_name":"Shanghai Mental Health Center","ror":"https://ror.org/05bd2wa15","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802690428"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jia Huang","raw_affiliation_strings":["Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong, University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong, University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2802690428"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102253461","display_name":"Zhiguang Lin","orcid":"https://orcid.org/0009-0005-0876-5707","observed_orcids":["https://orcid.org/0009-0005-0876-5707"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2802690428","display_name":"Shanghai Mental Health Center","ror":"https://ror.org/05bd2wa15","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802690428"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhiguang Lin","raw_affiliation_strings":["Department of Biochemistry, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2802690428"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072619665","display_name":"Yiru Fang","orcid":"https://orcid.org/0000-0002-8748-9085","observed_orcids":["https://orcid.org/0000-0002-8748-9085","https://orcid.org/0009-0008-3775-9412"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2802690428","display_name":"Shanghai Mental Health Center","ror":"https://ror.org/05bd2wa15","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802690428"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yiru Fang","raw_affiliation_strings":["Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: yirufang@aliyun.com","Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong, University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: yirufang@aliyun.com","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2802690428"]},{"raw_affiliation_string":"Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong, University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2802690428"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3790,"currency":"USD","value_usd":3790},"apc_paid":null,"fwci":4.079,"has_fulltext":false,"cited_by_count":63,"citation_normalized_percentile":{"value":0.93758722,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":99},"biblio":{"volume":"174","issue":null,"first_page":"361","last_page":"366"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10854","display_name":"Bipolar Disorder and Treatment","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10854","display_name":"Bipolar Disorder and Treatment","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11337","display_name":"Tryptophan and brain disorders","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2803","display_name":"Biological Psychiatry"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bipolar-i-disorder","display_name":"bipolar I disorder","score":0.9580000042915344},{"id":"https://openalex.org/keywords/manic-episodes","display_name":"manic episodes","score":0.9390000104904175},{"id":"https://openalex.org/keywords/il-23","display_name":"IL-23","score":0.9700000286102295},{"id":"https://openalex.org/keywords/tgf-beta1","display_name":"TGF-\u03b21","score":1.0},{"id":"https://openalex.org/keywords/pro-inflammatory-cytokines","display_name":"inflammatory cytokines","score":0.8889999985694885},{"id":"https://openalex.org/keywords/predictive-biomarkers","display_name":"predictive biomarkers","score":0.878000020980835},{"id":"https://openalex.org/keywords/quetiapine","display_name":"quetiapine","score":0.9399999976158142},{"id":"https://openalex.org/keywords/lithium","display_name":"lithium","score":0.968999981880188},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.8009999990463257},{"id":"https://openalex.org/keywords/il-17","display_name":"IL-17","score":1.0},{"id":"https://openalex.org/keywords/treatment-response","display_name":"treatment response","score":0.7070000171661377},{"id":"https://openalex.org/keywords/immune-dysfunction","display_name":"immune dysfunction","score":0.49000000953674316}],"concepts":[{"id":"https://openalex.org/C2780634440","wikidata":"https://www.wikidata.org/wiki/Q408535","display_name":"Quetiapine","level":3,"score":0.9290817379951477},{"id":"https://openalex.org/C2776174506","wikidata":"https://www.wikidata.org/wiki/Q131755","display_name":"Bipolar disorder","level":3,"score":0.7735645174980164},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6565017104148865},{"id":"https://openalex.org/C2778541603","wikidata":"https://www.wikidata.org/wiki/Q152763","display_name":"Lithium (medication)","level":2,"score":0.5949079990386963},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.559879720211029},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.5471888184547424},{"id":"https://openalex.org/C2988731192","wikidata":"https://www.wikidata.org/wiki/Q7410159","display_name":"Blood sampling","level":2,"score":0.44544968008995056},{"id":"https://openalex.org/C2778609679","wikidata":"https://www.wikidata.org/wiki/Q4915474","display_name":"Bipolar I disorder","level":5,"score":0.4152878522872925},{"id":"https://openalex.org/C10162356","wikidata":"https://www.wikidata.org/wiki/Q1135939","display_name":"Pathophysiology","level":2,"score":0.4139420986175537},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.33483389019966125},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.31612512469291687},{"id":"https://openalex.org/C2776412080","wikidata":"https://www.wikidata.org/wiki/Q7431605","display_name":"Schizophrenia (object-oriented programming)","level":2,"score":0.1844056248664856},{"id":"https://openalex.org/C2776809841","wikidata":"https://www.wikidata.org/wiki/Q185935","display_name":"Mania","level":4,"score":0.1591101884841919}],"mesh":[{"descriptor_ui":"D000069348","descriptor_name":"Quetiapine Fumarate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001714","descriptor_name":"Bipolar Disorder","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D001714","descriptor_name":"Bipolar Disorder","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D001714","descriptor_name":"Bipolar Disorder","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D003987","descriptor_name":"Dibenzothiazepines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014150","descriptor_name":"Antipsychotic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018020","descriptor_name":"Lithium Compounds","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D020381","descriptor_name":"Interleukin-17","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D053759","descriptor_name":"Interleukin-23","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D053773","descriptor_name":"Transforming Growth Factor beta1","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.jad.2014.12.033","doi":"https://doi.org/10.1016/j.jad.2014.12.033","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jad.2014.12.033","pdf_url":null,"source":{"id":"https://openalex.org/S113871862","display_name":"Journal of Affective Disorders","issn_l":"0165-0327","issn":["0165-0327","1573-2517"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Affective Disorders","raw_type":"journal-article"},{"id":"pmid:25545602","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25545602","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of affective disorders","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":58,"referenced_works":["https://openalex.org/W1483572459","https://openalex.org/W1690263224","https://openalex.org/W1967783468","https://openalex.org/W1969114959","https://openalex.org/W1970779770","https://openalex.org/W1971318940","https://openalex.org/W1978015084","https://openalex.org/W1978182767","https://openalex.org/W1978567629","https://openalex.org/W1990487655","https://openalex.org/W1993178195","https://openalex.org/W1994735594","https://openalex.org/W1996471148","https://openalex.org/W1996614926","https://openalex.org/W1997908175","https://openalex.org/W1997933206","https://openalex.org/W2004358501","https://openalex.org/W2014858274","https://openalex.org/W2017964415","https://openalex.org/W2019933066","https://openalex.org/W2021429334","https://openalex.org/W2031584576","https://openalex.org/W2033084955","https://openalex.org/W2033624423","https://openalex.org/W2037136952","https://openalex.org/W2039657509","https://openalex.org/W2039889159","https://openalex.org/W2048866565","https://openalex.org/W2054235049","https://openalex.org/W2058338914","https://openalex.org/W2059467700","https://openalex.org/W2060312436","https://openalex.org/W2064711537","https://openalex.org/W2066851422","https://openalex.org/W2067466132","https://openalex.org/W2082279387","https://openalex.org/W2087214416","https://openalex.org/W2087905758","https://openalex.org/W2087909308","https://openalex.org/W2089760657","https://openalex.org/W2091259554","https://openalex.org/W2091575312","https://openalex.org/W2092466307","https://openalex.org/W2121628766","https://openalex.org/W2123441818","https://openalex.org/W2131942594","https://openalex.org/W2147830699","https://openalex.org/W2147939477","https://openalex.org/W2150413247","https://openalex.org/W2154568166","https://openalex.org/W2163314276","https://openalex.org/W2164373099","https://openalex.org/W2164978865","https://openalex.org/W2167659819","https://openalex.org/W2209378722","https://openalex.org/W2776663677","https://openalex.org/W2991686196","https://openalex.org/W4238215801"],"related_works":["https://openalex.org/W2089760657","https://openalex.org/W7204156319","https://openalex.org/W2096853514","https://openalex.org/W2131942594","https://openalex.org/W2028131345","https://openalex.org/W2388223531","https://openalex.org/W32256297","https://openalex.org/W2058338914","https://openalex.org/W2377429252","https://openalex.org/W4395079456"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":7},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":10},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":5}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}