{"id":"https://openalex.org/W2016100228","doi":"https://doi.org/10.1016/j.ijpara.2008.09.001","title":"Hypoglycaemia induced by Trichinella infection is due to the increase of glucose uptake in infected muscle cells","display_name":"Hypoglycaemia induced by Trichinella infection is due to the increase of glucose uptake in infected muscle cells","publication_year":2008,"publication_date":"2008-09-23","ids":{"openalex":"https://openalex.org/W2016100228","doi":"https://doi.org/10.1016/j.ijpara.2008.09.001","mag":"2016100228","pmid":"https://pubmed.ncbi.nlm.nih.gov/18838075"},"language":"en","primary_location":{"id":"doi:10.1016/j.ijpara.2008.09.001","doi":"https://doi.org/10.1016/j.ijpara.2008.09.001","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ijpara.2008.09.001","pdf_url":null,"source":{"id":"https://openalex.org/S163169856","display_name":"International Journal for Parasitology","issn_l":"0020-7519","issn":["0020-7519","1879-0135"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal for Parasitology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034383217","display_name":"Zhiliang Wu","orcid":"https://orcid.org/0000-0002-5728-2462","observed_orcids":["https://orcid.org/0000-0002-5728-2462"]},"institutions":[{"id":"https://openalex.org/I42405503","display_name":"Gifu University","ror":"https://ror.org/024exxj48","country_code":"JP","type":"education","lineage":["https://openalex.org/I42405503"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Z. Wu","raw_affiliation_strings":["Department of Parasitology, Gifu University Graduate School of Medicine, Yanagido 1-1, Gifu 501-1194, Japan. wu@gifu-u.ac.jp","Department of Parasitology, Gifu University Graduate School of Medicine, Yanagido 1-1, Gifu, 501-1194 Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Parasitology, Gifu University Graduate School of Medicine, Yanagido 1-1, Gifu 501-1194, Japan. wu@gifu-u.ac.jp","institution_ids":["https://openalex.org/I42405503"]},{"raw_affiliation_string":"Department of Parasitology, Gifu University Graduate School of Medicine, Yanagido 1-1, Gifu, 501-1194 Japan","institution_ids":["https://openalex.org/I42405503"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108480592","display_name":"Isao NAGANO","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I42405503","display_name":"Gifu University","ror":"https://ror.org/024exxj48","country_code":"JP","type":"education","lineage":["https://openalex.org/I42405503"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"I. Nagano","raw_affiliation_strings":["Department of Parasitology, Gifu University Graduate School of Medicine, Yanagido 1-1, Gifu, 501-1194 Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Parasitology, Gifu University Graduate School of Medicine, Yanagido 1-1, Gifu, 501-1194 Japan","institution_ids":["https://openalex.org/I42405503"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049484965","display_name":"Kazuo Kajita","orcid":"https://orcid.org/0000-0003-0316-6412","observed_orcids":["https://orcid.org/0000-0003-0316-6412"]},"institutions":[{"id":"https://openalex.org/I42405503","display_name":"Gifu University","ror":"https://ror.org/024exxj48","country_code":"JP","type":"education","lineage":["https://openalex.org/I42405503"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"K. Kajita","raw_affiliation_strings":["Department of Parasitology, Gifu University Graduate School of Medicine, Yanagido 1-1, Gifu, 501-1194 Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Parasitology, Gifu University Graduate School of Medicine, Yanagido 1-1, Gifu, 501-1194 Japan","institution_ids":["https://openalex.org/I42405503"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109080861","display_name":"Masami Nishina","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I8588240","display_name":"Saitama Medical University","ror":"https://ror.org/04zb31v77","country_code":"JP","type":"education","lineage":["https://openalex.org/I8588240"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"M. Nishina","raw_affiliation_strings":["Medical Research Center, Saitama Medical University, 38 Morohongo Moroyama Irumagun, Saitama 350-0495, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Research Center, Saitama Medical University, 38 Morohongo Moroyama Irumagun, Saitama 350-0495, Japan","institution_ids":["https://openalex.org/I8588240"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081062260","display_name":"Yoshinori Takahashi","orcid":"https://orcid.org/0000-0001-8976-9614","observed_orcids":["https://orcid.org/0000-0001-8976-9614"]},"institutions":[{"id":"https://openalex.org/I42405503","display_name":"Gifu University","ror":"https://ror.org/024exxj48","country_code":"JP","type":"education","lineage":["https://openalex.org/I42405503"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Y. Takahashi","raw_affiliation_strings":["Department of Parasitology, Gifu University Graduate School of Medicine, Yanagido 1-1, Gifu, 501-1194 Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Parasitology, Gifu University Graduate School of Medicine, Yanagido 1-1, Gifu, 501-1194 Japan","institution_ids":["https://openalex.org/I42405503"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2880,"currency":"USD","value_usd":2880},"apc_paid":null,"fwci":0.2218,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":{"value":0.58270899,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"39","issue":"4","first_page":"427","last_page":"434"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11702","display_name":"Parasitic Diseases Research and Treatment","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11702","display_name":"Parasitic Diseases Research and Treatment","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10695","display_name":"Parasites and Host Interactions","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11074","display_name":"Helminth infection and control","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/trichinella-spiralis","display_name":"Trichinella spiralis","score":0.9449999928474426},{"id":"https://openalex.org/keywords/trichinella-pseudospiralis","display_name":"Trichinella pseudospiralis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/trichinellosis","display_name":"trichinellosis","score":0.9509999752044678},{"id":"https://openalex.org/keywords/hypoglycemia","display_name":"hypoglycemia","score":0.9810000061988831},{"id":"https://openalex.org/keywords/glucose-uptake","display_name":"glucose uptake","score":0.8970000147819519},{"id":"https://openalex.org/keywords/muscle-cells","display_name":"muscle cells","score":0.7289999723434448},{"id":"https://openalex.org/keywords/insulin-signaling-pathway","display_name":"insulin signaling pathway","score":0.9200000166893005},{"id":"https://openalex.org/keywords/insulin-receptor","display_name":"insulin receptor","score":0.8769999742507935},{"id":"https://openalex.org/keywords/irs-1","display_name":"IRS-1","score":0.8820000290870667},{"id":"https://openalex.org/keywords/irs2","display_name":"insulin receptor substrate 2","score":0.9959999918937683},{"id":"https://openalex.org/keywords/phosphatidylinositol-3-kinase","display_name":"phosphatidylinositol 3-kinase","score":0.7390000224113464},{"id":"https://openalex.org/keywords/akt2","display_name":"AKT2","score":0.9990000128746033},{"id":"https://openalex.org/keywords/glycogen-accumulation","display_name":"glycogen accumulation","score":0.9729999899864197},{"id":"https://openalex.org/keywords/larval-growth","display_name":"larval growth","score":0.6990000009536743},{"id":"https://openalex.org/keywords/host-parasite-interactions","display_name":"host-parasite interactions","score":0.8500000238418579}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8660502433776855},{"id":"https://openalex.org/C2777581317","wikidata":"https://www.wikidata.org/wiki/Q630285","display_name":"Trichinella","level":3,"score":0.8340691328048706},{"id":"https://openalex.org/C2781320125","wikidata":"https://www.wikidata.org/wiki/Q730937","display_name":"Trichinella spiralis","level":3,"score":0.6701164245605469},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.593292236328125},{"id":"https://openalex.org/C2780638806","wikidata":"https://www.wikidata.org/wiki/Q495146","display_name":"Trichinosis","level":3,"score":0.5622894167900085},{"id":"https://openalex.org/C112446052","wikidata":"https://www.wikidata.org/wiki/Q422579","display_name":"Insulin receptor","level":4,"score":0.5081052780151367},{"id":"https://openalex.org/C2777499176","wikidata":"https://www.wikidata.org/wiki/Q174936","display_name":"Glycogen","level":2,"score":0.5030688643455505},{"id":"https://openalex.org/C161573976","wikidata":"https://www.wikidata.org/wiki/Q420277","display_name":"Glucose transporter","level":3,"score":0.47506994009017944},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4715452492237091},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.448544442653656},{"id":"https://openalex.org/C2776415932","wikidata":"https://www.wikidata.org/wiki/Q48743","display_name":"Western blot","level":3,"score":0.44545674324035645},{"id":"https://openalex.org/C207200792","wikidata":"https://www.wikidata.org/wiki/Q428914","display_name":"Myocyte","level":2,"score":0.443392813205719},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.2613115906715393},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.237226665019989},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2115316390991211},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.18021130561828613},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.1015310287475586},{"id":"https://openalex.org/C165901193","wikidata":"https://www.wikidata.org/wiki/Q3129936","display_name":"Helminths","level":2,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006003","descriptor_name":"Glycogen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007003","descriptor_name":"Hypoglycemia","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D007003","descriptor_name":"Hypoglycemia","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007328","descriptor_name":"Insulin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008819","descriptor_name":"Mice, Nude","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014234","descriptor_name":"Trichinella","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014234","descriptor_name":"Trichinella","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014235","descriptor_name":"Trichinellosis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014235","descriptor_name":"Trichinellosis","qualifier_ui":"Q000469","qualifier_name":"parasitology","is_major_topic":false},{"descriptor_ui":"D015153","descriptor_name":"Blotting, Western","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017160","descriptor_name":"Trichinella spiralis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017160","descriptor_name":"Trichinella spiralis","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":false},{"descriptor_ui":"D019869","descriptor_name":"Phosphatidylinositol 3-Kinases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019869","descriptor_name":"Phosphatidylinositol 3-Kinases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020133","descriptor_name":"Reverse Transcriptase Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D032342","descriptor_name":"Muscle Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D032342","descriptor_name":"Muscle Cells","qualifier_ui":"Q000469","qualifier_name":"parasitology","is_major_topic":false},{"descriptor_ui":"D051057","descriptor_name":"Proto-Oncogene Proteins c-akt","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051057","descriptor_name":"Proto-Oncogene Proteins c-akt","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055504","descriptor_name":"Insulin Receptor Substrate Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D055504","descriptor_name":"Insulin Receptor Substrate Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.ijpara.2008.09.001","doi":"https://doi.org/10.1016/j.ijpara.2008.09.001","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ijpara.2008.09.001","pdf_url":null,"source":{"id":"https://openalex.org/S163169856","display_name":"International Journal for Parasitology","issn_l":"0020-7519","issn":["0020-7519","1879-0135"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal for Parasitology","raw_type":"journal-article"},{"id":"pmid:18838075","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18838075","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal for parasitology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320912","display_name":"Ministry of Education, Culture, Sports, Science and Technology","ror":"https://ror.org/048rj2z13"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":52,"referenced_works":["https://openalex.org/W1551443142","https://openalex.org/W1790384530","https://openalex.org/W1913992342","https://openalex.org/W1939706723","https://openalex.org/W1970301196","https://openalex.org/W1973425269","https://openalex.org/W1974186712","https://openalex.org/W1974649887","https://openalex.org/W1982046617","https://openalex.org/W1987300614","https://openalex.org/W1990802378","https://openalex.org/W1996828236","https://openalex.org/W1998932007","https://openalex.org/W1998991730","https://openalex.org/W2009181620","https://openalex.org/W2012831538","https://openalex.org/W2014967694","https://openalex.org/W2015038984","https://openalex.org/W2018010702","https://openalex.org/W2028625021","https://openalex.org/W2032151331","https://openalex.org/W2034397029","https://openalex.org/W2051105227","https://openalex.org/W2051731369","https://openalex.org/W2054006584","https://openalex.org/W2059294183","https://openalex.org/W2061412275","https://openalex.org/W2067633647","https://openalex.org/W2070732456","https://openalex.org/W2071602990","https://openalex.org/W2079440992","https://openalex.org/W2079518154","https://openalex.org/W2083547817","https://openalex.org/W2089127518","https://openalex.org/W2090830587","https://openalex.org/W2100701743","https://openalex.org/W2100943227","https://openalex.org/W2103586740","https://openalex.org/W2107751619","https://openalex.org/W2126712244","https://openalex.org/W2127985487","https://openalex.org/W2154145389","https://openalex.org/W2321899043","https://openalex.org/W2326641350","https://openalex.org/W2332167443","https://openalex.org/W2335234825","https://openalex.org/W2409816339","https://openalex.org/W2429283662","https://openalex.org/W3202459271","https://openalex.org/W6675043620","https://openalex.org/W6824535740","https://openalex.org/W7074051225"],"related_works":["https://openalex.org/W4385841056","https://openalex.org/W2603452019","https://openalex.org/W7009280882","https://openalex.org/W2054006584","https://openalex.org/W2412472720","https://openalex.org/W1973425269","https://openalex.org/W2411297876","https://openalex.org/W3016314907","https://openalex.org/W2107751619","https://openalex.org/W2007421599"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}