{"id":"https://openalex.org/W2016005073","doi":"https://doi.org/10.1016/j.yjmcc.2014.03.022","title":"Ventricular myosin modifies in vitro step-size when phosphorylated","display_name":"Ventricular myosin modifies in vitro step-size when phosphorylated","publication_year":2014,"publication_date":"2014-04-12","ids":{"openalex":"https://openalex.org/W2016005073","doi":"https://doi.org/10.1016/j.yjmcc.2014.03.022","mag":"2016005073","pmid":"https://pubmed.ncbi.nlm.nih.gov/24726887","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4037356"},"language":"en","primary_location":{"id":"doi:10.1016/j.yjmcc.2014.03.022","doi":"https://doi.org/10.1016/j.yjmcc.2014.03.022","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.yjmcc.2014.03.022","pdf_url":null,"source":{"id":"https://openalex.org/S111163638","display_name":"Journal of Molecular and Cellular Cardiology","issn_l":"0022-2828","issn":["0022-2828","1095-8584"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Molecular and Cellular Cardiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4037356","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100703461","display_name":"Yihua Wang","orcid":"https://orcid.org/0000-0002-7758-6738","observed_orcids":["https://orcid.org/0000-0002-7758-6738"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yihua Wang","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, United States","****Mayo Clinic, Rochester, MN USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, United States","institution_ids":[]},{"raw_affiliation_string":"****Mayo Clinic, Rochester, MN USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013390724","display_name":"Katalin Ajtai","orcid":"https://orcid.org/0000-0002-4976-5528","observed_orcids":["https://orcid.org/0000-0002-4976-5528"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Katalin Ajtai","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, United States","****Mayo Clinic, Rochester, MN USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, United States","institution_ids":[]},{"raw_affiliation_string":"****Mayo Clinic, Rochester, MN USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5022370263","display_name":"Thomas P. Burghardt","orcid":"https://orcid.org/0000-0003-3119-4074","observed_orcids":["https://orcid.org/0000-0003-3119-4074"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Thomas P. Burghardt","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, United States; Department of Physiology and Biomedical Engineering, United States. Electronic address: burghardt@mayo.edu","****Mayo Clinic, Rochester, MN USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, United States; Department of Physiology and Biomedical Engineering, United States. Electronic address: burghardt@mayo.edu","institution_ids":[]},{"raw_affiliation_string":"****Mayo Clinic, Rochester, MN USA","institution_ids":["https://openalex.org/I1330342723"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5022370263"],"corresponding_institution_ids":["https://openalex.org/I1330342723"],"apc_list":{"value":4120,"currency":"USD","value_usd":4120},"apc_paid":null,"fwci":4.1165,"has_fulltext":false,"cited_by_count":38,"citation_normalized_percentile":{"value":0.94535712,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"72","issue":null,"first_page":"231","last_page":"237"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cardiac-myosin","display_name":"cardiac myosin","score":0.8460000157356262},{"id":"https://openalex.org/keywords/regulatory-light-chain-phosphorylation","display_name":"regulatory light chain phosphorylation","score":0.8859999775886536},{"id":"https://openalex.org/keywords/beta-cardiac-myosin","display_name":"\u03b2-cardiac myosin","score":0.6779999732971191},{"id":"https://openalex.org/keywords/essential-light-chain","display_name":"essential light chain","score":0.6959999799728394},{"id":"https://openalex.org/keywords/actin-myosin-interaction","display_name":"actin-myosin interaction","score":0.5070000290870667}],"concepts":[{"id":"https://openalex.org/C6997183","wikidata":"https://www.wikidata.org/wiki/Q271727","display_name":"Myosin","level":2,"score":0.8534585237503052},{"id":"https://openalex.org/C11960822","wikidata":"https://www.wikidata.org/wiki/Q242736","display_name":"Phosphorylation","level":2,"score":0.6439852714538574},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.5884115695953369},{"id":"https://openalex.org/C125705527","wikidata":"https://www.wikidata.org/wiki/Q185269","display_name":"Actin","level":2,"score":0.5837209224700928},{"id":"https://openalex.org/C15954220","wikidata":"https://www.wikidata.org/wiki/Q24780076","display_name":"Myosin head","level":4,"score":0.5718761086463928},{"id":"https://openalex.org/C2776050358","wikidata":"https://www.wikidata.org/wiki/Q127006","display_name":"Muscle contraction","level":2,"score":0.5005297660827637},{"id":"https://openalex.org/C2778021804","wikidata":"https://www.wikidata.org/wiki/Q13359586","display_name":"Myosin ATPase","level":4,"score":0.47617167234420776},{"id":"https://openalex.org/C18923293","wikidata":"https://www.wikidata.org/wiki/Q6819942","display_name":"Meromyosin","level":5,"score":0.4707786738872528},{"id":"https://openalex.org/C14228908","wikidata":"https://www.wikidata.org/wiki/Q2920483","display_name":"Protein filament","level":2,"score":0.4617173373699188},{"id":"https://openalex.org/C23265538","wikidata":"https://www.wikidata.org/wiki/Q300033","display_name":"ATPase","level":3,"score":0.43945932388305664},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.40911567211151123},{"id":"https://openalex.org/C8035138","wikidata":"https://www.wikidata.org/wiki/Q6017854","display_name":"Myosin light-chain kinase","level":3,"score":0.39890027046203613},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.37328261137008667},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2700856328010559},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.1226203441619873},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.09760111570358276}],"mesh":[{"descriptor_ui":"D000199","descriptor_name":"Actins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000255","descriptor_name":"Adenosine Triphosphate","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001696","descriptor_name":"Biomechanical Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D009200","descriptor_name":"Myocardial Contraction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010766","descriptor_name":"Phosphorylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018994","descriptor_name":"Myosin Light Chains","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D024723","descriptor_name":"Ventricular Myosins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D045663","descriptor_name":"Quantum Dots","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.yjmcc.2014.03.022","doi":"https://doi.org/10.1016/j.yjmcc.2014.03.022","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.yjmcc.2014.03.022","pdf_url":null,"source":{"id":"https://openalex.org/S111163638","display_name":"Journal of Molecular and Cellular Cardiology","issn_l":"0022-2828","issn":["0022-2828","1095-8584"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Molecular and Cellular Cardiology","raw_type":"journal-article"},{"id":"pmid:24726887","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24726887","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of molecular and cellular cardiology","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:3445404","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4037356","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4037356","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4037356","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Mol Cell Cardiol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:3445404","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4037356","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/7","score":0.75,"display_name":"Affordable and clean energy"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G199658164","display_name":"Visualizing Actomyosin Transients by Data Merging","funder_award_id":"R01AR049277","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G5071608702","display_name":"In Situ Sensing of Single Myosin Function in Hypertrophy Disease","funder_award_id":"R01HL095572","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G5715889743","display_name":null,"funder_award_id":"R01HL095572","funder_id":"https://openalex.org/F4320309464","funder_display_name":"Mayo Foundation for Medical Education and Research"},{"id":"https://openalex.org/G9000902408","display_name":"Baylor College of Medicine Cancer Center - Cancer Center Support Grant","funder_award_id":"P30CA125123","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320309464","display_name":"Mayo Foundation for Medical Education and Research","ror":"https://ror.org/02qp3tb03"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337362","display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","ror":"https://ror.org/006zn3t30"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W149540474","https://openalex.org/W1508733727","https://openalex.org/W1535644751","https://openalex.org/W1964511529","https://openalex.org/W1968894591","https://openalex.org/W1976053070","https://openalex.org/W1982469770","https://openalex.org/W1987012637","https://openalex.org/W1999631496","https://openalex.org/W2009323056","https://openalex.org/W2036104448","https://openalex.org/W2036738288","https://openalex.org/W2038103542","https://openalex.org/W2049890414","https://openalex.org/W2052693663","https://openalex.org/W2054603530","https://openalex.org/W2057946529","https://openalex.org/W2058497997","https://openalex.org/W2058608440","https://openalex.org/W2075464765","https://openalex.org/W2079149254","https://openalex.org/W2096102024","https://openalex.org/W2098548847","https://openalex.org/W2106879388","https://openalex.org/W2109579264","https://openalex.org/W2111015914","https://openalex.org/W2119318217","https://openalex.org/W2141083815","https://openalex.org/W2148046764","https://openalex.org/W2153435210","https://openalex.org/W2162456067","https://openalex.org/W2170133492"],"related_works":["https://openalex.org/W2607075618","https://openalex.org/W2052693663","https://openalex.org/W2300301062","https://openalex.org/W2327556397","https://openalex.org/W2136347317","https://openalex.org/W2802235816","https://openalex.org/W2106879388","https://openalex.org/W4409098728","https://openalex.org/W4400114038","https://openalex.org/W2485959475"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":4},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}