{"id":"https://openalex.org/W2015790897","doi":"https://doi.org/10.1115/1.4023525","title":"In Vitro Pulsatility Analysis of Axial-Flow and Centrifugal-Flow Left Ventricular Assist Devices","display_name":"In Vitro Pulsatility Analysis of Axial-Flow and Centrifugal-Flow Left Ventricular Assist Devices","publication_year":2013,"publication_date":"2013-01-29","ids":{"openalex":"https://openalex.org/W2015790897","doi":"https://doi.org/10.1115/1.4023525","mag":"2015790897","pmid":"https://pubmed.ncbi.nlm.nih.gov/24231821","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3705790"},"language":"en","primary_location":{"id":"doi:10.1115/1.4023525","doi":"https://doi.org/10.1115/1.4023525","is_oa":false,"landing_page_url":"https://doi.org/10.1115/1.4023525","pdf_url":null,"source":{"id":"https://openalex.org/S4210187999","display_name":"Journal of Biomechanical Engineering","issn_l":"0148-0731","issn":["0148-0731","1528-8951"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310316053","host_organization_name":"ASM International","host_organization_lineage":["https://openalex.org/P4310316053"],"host_organization_lineage_names":["ASM International"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomechanical Engineering","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/articles/PMC3705790","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001653201","display_name":"J. Ryan Stanfield","orcid":"https://orcid.org/0009-0005-8265-6867","observed_orcids":["https://orcid.org/0009-0005-8265-6867"]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Ryan Stanfield","raw_affiliation_strings":["Department of Mechanical Engineering, University of Utah, 50\u2009S Central Campus Dr., Rm. 2110, Salt Lake City, UT 84112 e-mail:"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Mechanical Engineering, University of Utah, 50\u2009S Central Campus Dr., Rm. 2110, Salt Lake City, UT 84112 e-mail:","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031493840","display_name":"Craig H. Selzman","orcid":"https://orcid.org/0000-0001-9218-4764","observed_orcids":["https://orcid.org/0000-0001-9218-4764"]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Craig H. Selzman","raw_affiliation_strings":["Department of Surgery, Division of Cardiothoracic Surgery, University of Utah, 30\u2009N 1900\u2009E, SOM 3C127, Salt Lake City, UT 84132"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Division of Cardiothoracic Surgery, University of Utah, 30\u2009N 1900\u2009E, SOM 3C127, Salt Lake City, UT 84132","institution_ids":["https://openalex.org/I223532165"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I223532165"],"apc_list":null,"apc_paid":null,"fwci":1.8366,"has_fulltext":false,"cited_by_count":33,"citation_normalized_percentile":{"value":0.8368467,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"135","issue":"3","first_page":"34505","last_page":"34505"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10675","display_name":"Mechanical Circulatory Support Devices","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10675","display_name":"Mechanical Circulatory Support Devices","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10300","display_name":"Congenital Heart Disease Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/left-ventricular-assist-device","display_name":"left ventricular assist device","score":0.9259999990463257},{"id":"https://openalex.org/keywords/continuous-flow-ventricular-assist-device","display_name":"continuous flow ventricular assist device","score":0.7960000038146973},{"id":"https://openalex.org/keywords/pulsatility","display_name":"pulsatility","score":0.7960000038146973},{"id":"https://openalex.org/keywords/pulsatility-index","display_name":"pulsatility index","score":0.9039999842643738},{"id":"https://openalex.org/keywords/axial-flow-pump","display_name":"axial flow pump","score":0.9290000200271606},{"id":"https://openalex.org/keywords/centrifugal-flow-pump","display_name":"centrifugal flow pump","score":0.9990000128746033},{"id":"https://openalex.org/keywords/advanced-heart-failure","display_name":"advanced heart failure","score":0.796999990940094},{"id":"https://openalex.org/keywords/mock-circulatory-loop","display_name":"mock circulatory loop","score":0.7940000295639038},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.5120000243186951},{"id":"https://openalex.org/keywords/hypotension","display_name":"hypotension","score":0.9769999980926514}],"concepts":[{"id":"https://openalex.org/C79191276","wikidata":"https://www.wikidata.org/wiki/Q7259620","display_name":"Pulsatile flow","level":2,"score":0.9463891983032227},{"id":"https://openalex.org/C153005164","wikidata":"https://www.wikidata.org/wiki/Q1698700","display_name":"Impeller","level":2,"score":0.8016208410263062},{"id":"https://openalex.org/C166675230","wikidata":"https://www.wikidata.org/wiki/Q627111","display_name":"Centrifugal pump","level":3,"score":0.7022511959075928},{"id":"https://openalex.org/C2778774980","wikidata":"https://www.wikidata.org/wiki/Q2897721","display_name":"Ventricular assist device","level":3,"score":0.643103837966919},{"id":"https://openalex.org/C180788929","wikidata":"https://www.wikidata.org/wiki/Q742777","display_name":"Axial compressor","level":3,"score":0.6067963242530823},{"id":"https://openalex.org/C38349280","wikidata":"https://www.wikidata.org/wiki/Q1434290","display_name":"Flow (mathematics)","level":2,"score":0.5558837652206421},{"id":"https://openalex.org/C72859922","wikidata":"https://www.wikidata.org/wiki/Q11068","display_name":"Circulatory system","level":2,"score":0.5515965819358826},{"id":"https://openalex.org/C2778921608","wikidata":"https://www.wikidata.org/wiki/Q2002035","display_name":"Ventricle","level":2,"score":0.528965175151825},{"id":"https://openalex.org/C158846371","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Blood flow","level":2,"score":0.486975759267807},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.48241767287254333},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4433111548423767},{"id":"https://openalex.org/C166693061","wikidata":"https://www.wikidata.org/wiki/Q5462119","display_name":"Flow velocity","level":3,"score":0.43393439054489136},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.38783660531044006},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3674509525299072},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.3583037257194519},{"id":"https://openalex.org/C57879066","wikidata":"https://www.wikidata.org/wiki/Q41217","display_name":"Mechanics","level":1,"score":0.3053978681564331},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.16201066970825195},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.1471443474292755},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.09036478400230408},{"id":"https://openalex.org/C131097465","wikidata":"https://www.wikidata.org/wiki/Q178898","display_name":"Gas compressor","level":2,"score":0.06609117984771729}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002498","descriptor_name":"Centrifugation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006353","descriptor_name":"Heart-Assist Devices","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057446","descriptor_name":"Hydrodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1115/1.4023525","doi":"https://doi.org/10.1115/1.4023525","is_oa":false,"landing_page_url":"https://doi.org/10.1115/1.4023525","pdf_url":null,"source":{"id":"https://openalex.org/S4210187999","display_name":"Journal of Biomechanical Engineering","issn_l":"0148-0731","issn":["0148-0731","1528-8951"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310316053","host_organization_name":"ASM International","host_organization_lineage":["https://openalex.org/P4310316053"],"host_organization_lineage_names":["ASM International"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomechanical Engineering","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2921778","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC3705790","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3705790","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3705790","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Biomech Eng","raw_type":"Text"},{"id":"pmid:24231821","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24231821","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of biomechanical engineering","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2921778","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC3705790","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"score":0.8560000061988831,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G7337428104","display_name":"Mechanisms of Myocardial Recovery","funder_award_id":"R01HL089592","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W1969574965","https://openalex.org/W1971207398","https://openalex.org/W1986475842","https://openalex.org/W1994174663","https://openalex.org/W1995229219","https://openalex.org/W1999886145","https://openalex.org/W2010798210","https://openalex.org/W2019534498","https://openalex.org/W2033186409","https://openalex.org/W2056963221","https://openalex.org/W2059113864","https://openalex.org/W2059970701","https://openalex.org/W2073666032","https://openalex.org/W2079613552","https://openalex.org/W2079985818","https://openalex.org/W2081024528","https://openalex.org/W2082694184","https://openalex.org/W2084360339","https://openalex.org/W2087708854","https://openalex.org/W2094193738","https://openalex.org/W2117415793","https://openalex.org/W2138080145","https://openalex.org/W2165719156","https://openalex.org/W2170868366","https://openalex.org/W2313098680","https://openalex.org/W2330218830","https://openalex.org/W2410825642"],"related_works":["https://openalex.org/W4225792945","https://openalex.org/W1986475842","https://openalex.org/W4310088402","https://openalex.org/W2046399169","https://openalex.org/W2167944041","https://openalex.org/W2019534498","https://openalex.org/W2617721715","https://openalex.org/W1984641978","https://openalex.org/W2311401489","https://openalex.org/W2081913215"],"abstract_inverted_index":{"Recently,":[0],"continuous-flow":[1,51],"ventricular":[2],"assist":[3],"devices":[4,108,204],"(CF-VADs)":[5],"have":[6],"supplanted":[7],"older,":[8],"pulsatile-flow":[9,191],"pumps,":[10,157],"for":[11,101,130,152,173],"treating":[12],"patients":[13],"with":[14,196],"advanced":[15],"heart":[16],"failure.":[17],"Despite":[18],"the":[19,23,27,44,131,153,174,206,210],"excellent":[20],"results":[21],"of":[22,29,32,38,46,115,188,212],"newer":[24],"generation":[25],"devices,":[26],"effects":[28],"long-term":[30],"loss":[31],"pulsatility":[33,56],"remain":[34],"unknown.":[35],"The":[36],"aim":[37],"this":[39],"study":[40],"is":[41],"to":[42,53],"compare":[43],"ability":[45],"both":[47],"axial":[48,132,154,175,207],"and":[49,67,94,126,133,148,155,169,176],"centrifugal":[50,134,156,177],"pumps":[52,208],"intrinsically":[54],"modify":[55],"when":[57,192],"placed":[58],"under":[59,104,214],"physiologically":[60],"diverse":[61],"conditions.":[62,216],"Four":[63],"VADs,":[64],"two":[65,68],"axial-":[66],"centrifugal-flow,":[69],"were":[70,186],"evaluated":[71],"on":[72],"a":[73,83,110],"mock":[74,198],"circulatory":[75],"flow":[76,120,142],"system.":[77],"Each":[78],"VAD":[79],"was":[80,99,122,144,165],"operated":[81],"at":[82],"constant":[84],"impeller":[85],"speed":[86],"over":[87],"three":[88],"hypothetical":[89],"cardiac":[90],"conditions:":[91],"normo-tensive,":[92],"hypertensive,":[93],"hypotensive.":[95],"Pulsatility":[96],"index":[97],"(PI)":[98],"compared":[100],"each":[102,105],"device":[103],"condition.":[106],"Centrifugal-flow":[107],"had":[109],"higher":[111],"PI":[112,121,143,164,213],"than":[113],"that":[114,202],"axial-flow":[116],"pumps.":[117],"Under":[118,140,162],"normo-tension,":[119],"0.98":[123],"\u00b1":[124,128,146,150,167,171],"0.03":[125],"1.50":[127],"0.02":[129,168,172],"groups,":[135,178],"respectively":[136,158,179],"(p":[137,159,180],"<":[138],"0.01).":[139,161],"hypertension,":[141],"1.90":[145],"0.16":[147],"4.21":[149],"0.29":[151],"=":[160,181],"hypotension,":[163],"0.73":[166],"0.78":[170],"0.13).":[182],"All":[183],"tested":[184,215],"CF-VADs":[185],"capable":[187],"maintaining":[189],"some":[190],"connected":[193],"in":[194],"parallel":[195],"our":[197],"ventricle.":[199],"We":[200],"conclude":[201],"centrifugal-flow":[203],"outperform":[205],"from":[209],"basis":[211]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":4},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}