{"id":"https://openalex.org/W2015705736","doi":"https://doi.org/10.1007/s00018-011-0760-0","title":"The biology of interleukin-1: emerging concepts in the regulation of the actin cytoskeleton and cell junction dynamics","display_name":"The biology of interleukin-1: emerging concepts in the regulation of the actin cytoskeleton and cell junction dynamics","publication_year":2011,"publication_date":"2011-07-08","ids":{"openalex":"https://openalex.org/W2015705736","doi":"https://doi.org/10.1007/s00018-011-0760-0","mag":"2015705736","pmid":"https://pubmed.ncbi.nlm.nih.gov/21744066","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3297025"},"language":"en","primary_location":{"id":"doi:10.1007/s00018-011-0760-0","doi":"https://doi.org/10.1007/s00018-011-0760-0","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00018-011-0760-0","pdf_url":null,"source":{"id":"https://openalex.org/S60362788","display_name":"Cellular and Molecular Life Sciences","issn_l":"1420-682X","issn":["1420-682X","1420-9071"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cellular and Molecular Life Sciences","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3297025","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000133136","display_name":"Pearl P.Y. Lie","orcid":"https://orcid.org/0000-0001-5838-958X","observed_orcids":["https://orcid.org/0000-0001-5838-958X"]},"institutions":[{"id":"https://openalex.org/I1314022388","display_name":"Population Council","ror":"https://ror.org/052ce7c92","country_code":"IN","type":"nonprofit","lineage":["https://openalex.org/I1314022388"]},{"id":"https://openalex.org/I4210132262","display_name":"Population Council","ror":"https://ror.org/03zjj0p70","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210132262"]}],"countries":["IN","US"],"is_corresponding":false,"raw_author_name":"Pearl P. Y. Lie","raw_affiliation_strings":["Center for Biomedical Research, Population Council, 1230 York Avenue, New York, NY 10065, USA","Population Council"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Biomedical Research, Population Council, 1230 York Avenue, New York, NY 10065, USA","institution_ids":["https://openalex.org/I4210132262"]},{"raw_affiliation_string":"Population Council","institution_ids":["https://openalex.org/I1314022388","https://openalex.org/I4210132262"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072413923","display_name":"C. Yan Cheng","orcid":"https://orcid.org/0000-0003-3117-3791","observed_orcids":["https://orcid.org/0000-0003-3117-3791"]},"institutions":[{"id":"https://openalex.org/I1314022388","display_name":"Population Council","ror":"https://ror.org/052ce7c92","country_code":"IN","type":"nonprofit","lineage":["https://openalex.org/I1314022388"]},{"id":"https://openalex.org/I4210132262","display_name":"Population Council","ror":"https://ror.org/03zjj0p70","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210132262"]}],"countries":["IN","US"],"is_corresponding":false,"raw_author_name":"C. Yan Cheng","raw_affiliation_strings":["Center for Biomedical Research, Population Council, 1230 York Avenue, New York, NY, 10065, USA","Population Council"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Biomedical Research, Population Council, 1230 York Avenue, New York, NY, 10065, USA","institution_ids":["https://openalex.org/I4210132262"]},{"raw_affiliation_string":"Population Council","institution_ids":["https://openalex.org/I1314022388","https://openalex.org/I4210132262"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041273456","display_name":"Dolores D. Mruk","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1314022388","display_name":"Population Council","ror":"https://ror.org/052ce7c92","country_code":"IN","type":"nonprofit","lineage":["https://openalex.org/I1314022388"]},{"id":"https://openalex.org/I4210132262","display_name":"Population Council","ror":"https://ror.org/03zjj0p70","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210132262"]}],"countries":["IN","US"],"is_corresponding":true,"raw_author_name":"Dolores D. Mruk","raw_affiliation_strings":["Center for Biomedical Research, Population Council, 1230 York Avenue, New York, NY, 10065, USA","Population Council"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Biomedical Research, Population Council, 1230 York Avenue, New York, NY, 10065, USA","institution_ids":["https://openalex.org/I4210132262"]},{"raw_affiliation_string":"Population Council","institution_ids":["https://openalex.org/I1314022388","https://openalex.org/I4210132262"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5041273456"],"corresponding_institution_ids":["https://openalex.org/I1314022388","https://openalex.org/I4210132262"],"apc_list":{"value":4290,"currency":"USD","value_usd":4290},"apc_paid":null,"fwci":0.2636,"has_fulltext":false,"cited_by_count":41,"citation_normalized_percentile":{"value":0.3241573,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"69","issue":"4","first_page":"487","last_page":"500"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11503","display_name":"Cytokine Signaling Pathways and Interactions","score":0.6582000255584717,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11503","display_name":"Cytokine Signaling Pathways and Interactions","score":0.6582000255584717,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.186599999666214,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.031099999323487282,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/interleukin-1","display_name":"interleukin-1","score":0.9990000128746033},{"id":"https://openalex.org/keywords/interleukin-1-alpha","display_name":"interleukin-1 alpha","score":0.7870000004768372},{"id":"https://openalex.org/keywords/actin-cytoskeleton","display_name":"actin cytoskeleton","score":0.949999988079071},{"id":"https://openalex.org/keywords/cell-junctions","display_name":"cell junctions","score":0.8870000243186951},{"id":"https://openalex.org/keywords/seminiferous-epithelium","display_name":"seminiferous epithelium","score":0.8920000195503235},{"id":"https://openalex.org/keywords/spermatogenesis","display_name":"spermatogenesis","score":0.996999979019165},{"id":"https://openalex.org/keywords/innate-immunity","display_name":"innate immunity","score":0.8069999814033508},{"id":"https://openalex.org/keywords/pro-inflammatory-cytokines","display_name":"inflammatory cytokines","score":0.8429999947547913},{"id":"https://openalex.org/keywords/testis","display_name":"testis","score":0.49900001287460327}],"concepts":[{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.8213475942611694},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6626896858215332},{"id":"https://openalex.org/C2993400109","wikidata":"https://www.wikidata.org/wiki/Q329638","display_name":"Actin cytoskeleton","level":4,"score":0.6604841947555542},{"id":"https://openalex.org/C142669718","wikidata":"https://www.wikidata.org/wiki/Q154626","display_name":"Cytoskeleton","level":3,"score":0.5989429950714111},{"id":"https://openalex.org/C125705527","wikidata":"https://www.wikidata.org/wiki/Q185269","display_name":"Actin","level":2,"score":0.5645537972450256},{"id":"https://openalex.org/C203253989","wikidata":"https://www.wikidata.org/wiki/Q419052","display_name":"Profilin","level":5,"score":0.4465901851654053},{"id":"https://openalex.org/C164027704","wikidata":"https://www.wikidata.org/wiki/Q3491837","display_name":"Proinflammatory cytokine","level":3,"score":0.4457825720310211},{"id":"https://openalex.org/C529295009","wikidata":"https://www.wikidata.org/wiki/Q41301","display_name":"Epithelium","level":2,"score":0.43333759903907776},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.3770591914653778},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.30448096990585327},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.23899516463279724},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.07631736993789673}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007365","descriptor_name":"Intercellular Junctions","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D007375","descriptor_name":"Interleukin-1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D007375","descriptor_name":"Interleukin-1","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008841","descriptor_name":"Actin Cytoskeleton","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013091","descriptor_name":"Spermatogenesis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016328","descriptor_name":"NF-kappa B","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020741","descriptor_name":"rho GTP-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1007/s00018-011-0760-0","doi":"https://doi.org/10.1007/s00018-011-0760-0","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00018-011-0760-0","pdf_url":null,"source":{"id":"https://openalex.org/S60362788","display_name":"Cellular and Molecular Life Sciences","issn_l":"1420-682X","issn":["1420-682X","1420-9071"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cellular and Molecular Life Sciences","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2561216","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3297025","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3297025","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3297025","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Mol Life Sci","raw_type":"Text"},{"id":"pmid:21744066","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21744066","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cellular and molecular life sciences : CMLS","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2561216","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3297025","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.428600013256073}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2880103442","display_name":"Biology of the Blood-Testis Barrier","funder_award_id":"R01HD056034","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G6278142320","display_name":"Biology of desmosome-gap junctions in the testis","funder_award_id":"R03HD061401","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G7913906242","display_name":"Cooperative Contraceptive Research Center: New Contraceptives with Dual Benefits","funder_award_id":"U54HD029990","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"}],"funders":[{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":159,"referenced_works":["https://openalex.org/W20888715","https://openalex.org/W121387658","https://openalex.org/W591684825","https://openalex.org/W1514081838","https://openalex.org/W1515994079","https://openalex.org/W1517625476","https://openalex.org/W1527048315","https://openalex.org/W1529674879","https://openalex.org/W1542467604","https://openalex.org/W1565698096","https://openalex.org/W1571384054","https://openalex.org/W1577941646","https://openalex.org/W1600430222","https://openalex.org/W1618627661","https://openalex.org/W1624946627","https://openalex.org/W1824528611","https://openalex.org/W1834617037","https://openalex.org/W1881806304","https://openalex.org/W1885912605","https://openalex.org/W1886532757","https://openalex.org/W1902824041","https://openalex.org/W1964157134","https://openalex.org/W1964977785","https://openalex.org/W1965737875","https://openalex.org/W1967413976","https://openalex.org/W1967980238","https://openalex.org/W1969501356","https://openalex.org/W1970195004","https://openalex.org/W1973585961","https://openalex.org/W1975615008","https://openalex.org/W1976444831","https://openalex.org/W1977874001","https://openalex.org/W1978677736","https://openalex.org/W1981163610","https://openalex.org/W1983735042","https://openalex.org/W1987082843","https://openalex.org/W1991830749","https://openalex.org/W1993083609","https://openalex.org/W1993409946","https://openalex.org/W1993744541","https://openalex.org/W1994772331","https://openalex.org/W1994785184","https://openalex.org/W1995622771","https://openalex.org/W1997078828","https://openalex.org/W1998145026","https://openalex.org/W1998585620","https://openalex.org/W2004878760","https://openalex.org/W2005035542","https://openalex.org/W2005537768","https://openalex.org/W2006432534","https://openalex.org/W2006509394","https://openalex.org/W2007660746","https://openalex.org/W2008202400","https://openalex.org/W2008261126","https://openalex.org/W2012107438","https://openalex.org/W2013667986","https://openalex.org/W2014042259","https://openalex.org/W2014551385","https://openalex.org/W2014913899","https://openalex.org/W2015174250","https://openalex.org/W2016710605","https://openalex.org/W2018699957","https://openalex.org/W2019983300","https://openalex.org/W2022581791","https://openalex.org/W2028444662","https://openalex.org/W2028564194","https://openalex.org/W2031311121","https://openalex.org/W2031434196","https://openalex.org/W2032158597","https://openalex.org/W2034382620","https://openalex.org/W2034520471","https://openalex.org/W2039795039","https://openalex.org/W2043615134","https://openalex.org/W2045487670","https://openalex.org/W2045527675","https://openalex.org/W2046440869","https://openalex.org/W2048096874","https://openalex.org/W2050022968","https://openalex.org/W2050440433","https://openalex.org/W2051556121","https://openalex.org/W2051645404","https://openalex.org/W2051658957","https://openalex.org/W2052461680","https://openalex.org/W2054418119","https://openalex.org/W2063781137","https://openalex.org/W2064434771","https://openalex.org/W2064711537","https://openalex.org/W2065959414","https://openalex.org/W2067711610","https://openalex.org/W2070144391","https://openalex.org/W2070731858","https://openalex.org/W2071199281","https://openalex.org/W2072791668","https://openalex.org/W2073602707","https://openalex.org/W2073882423","https://openalex.org/W2074213282","https://openalex.org/W2074729751","https://openalex.org/W2074859762","https://openalex.org/W2075229853","https://openalex.org/W2077080652","https://openalex.org/W2078136106","https://openalex.org/W2079122334","https://openalex.org/W2081223653","https://openalex.org/W2081797353","https://openalex.org/W2083829960","https://openalex.org/W2084383502","https://openalex.org/W2084655958","https://openalex.org/W2088800018","https://openalex.org/W2089867981","https://openalex.org/W2089991241","https://openalex.org/W2090940048","https://openalex.org/W2093096778","https://openalex.org/W2093187124","https://openalex.org/W2094234363","https://openalex.org/W2102312968","https://openalex.org/W2104424074","https://openalex.org/W2105746559","https://openalex.org/W2107219745","https://openalex.org/W2111045447","https://openalex.org/W2112115346","https://openalex.org/W2112358444","https://openalex.org/W2114347295","https://openalex.org/W2114769428","https://openalex.org/W2115867185","https://openalex.org/W2116101489","https://openalex.org/W2117430507","https://openalex.org/W2121560754","https://openalex.org/W2123610543","https://openalex.org/W2123882810","https://openalex.org/W2133892659","https://openalex.org/W2134632062","https://openalex.org/W2136761840","https://openalex.org/W2143092625","https://openalex.org/W2143266180","https://openalex.org/W2145562458","https://openalex.org/W2150102283","https://openalex.org/W2153164047","https://openalex.org/W2153452459","https://openalex.org/W2155916024","https://openalex.org/W2157710399","https://openalex.org/W2158447646","https://openalex.org/W2158490827","https://openalex.org/W2159150621","https://openalex.org/W2163150558","https://openalex.org/W2164606029","https://openalex.org/W2164929923","https://openalex.org/W2165275387","https://openalex.org/W2167158605","https://openalex.org/W2252403865","https://openalex.org/W2413915964","https://openalex.org/W2416138507","https://openalex.org/W4210987759","https://openalex.org/W4211041578","https://openalex.org/W4230369210","https://openalex.org/W4231460341","https://openalex.org/W4235834558","https://openalex.org/W4240354993","https://openalex.org/W4241204613","https://openalex.org/W4241419271"],"related_works":["https://openalex.org/W2158490827","https://openalex.org/W2048096874","https://openalex.org/W1999809584","https://openalex.org/W2164862068","https://openalex.org/W2511370118","https://openalex.org/W4231460341","https://openalex.org/W2073686351","https://openalex.org/W2029657458","https://openalex.org/W2413225886","https://openalex.org/W2060172716"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
