{"id":"https://openalex.org/W2015668790","doi":"https://doi.org/10.1016/j.bbmt.2011.12.529","title":"Unrelated Cord Blood Transplantation (CBT) of 101 Hemoglobinopathy (HGB) Patients","display_name":"Unrelated Cord Blood Transplantation (CBT) of 101 Hemoglobinopathy (HGB) Patients","publication_year":2012,"publication_date":"2012-01-10","ids":{"openalex":"https://openalex.org/W2015668790","doi":"https://doi.org/10.1016/j.bbmt.2011.12.529","mag":"2015668790"},"language":"en","primary_location":{"id":"doi:10.1016/j.bbmt.2011.12.529","doi":"https://doi.org/10.1016/j.bbmt.2011.12.529","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbmt.2011.12.529","pdf_url":"http://www.astctjournal.org/article/S1083879111010913/pdf","source":{"id":"https://openalex.org/S59987174","display_name":"Transplantation and Cellular Therapy","issn_l":"1083-8791","issn":["1083-8791","1523-6536","2666-6367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of Blood and Marrow Transplantation","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"http://www.astctjournal.org/article/S1083879111010913/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103709103","display_name":"Robert Chow","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210089186","display_name":"StemCyte","ror":"https://ror.org/00bekwh77","country_code":"US","type":"other","lineage":["https://openalex.org/I4210089186"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R.Y. Chow","raw_affiliation_strings":["StemCyte, Inc., Covina, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"StemCyte, Inc., Covina, CA","institution_ids":["https://openalex.org/I4210089186"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048917138","display_name":"Tang\u2010Her Jaing","orcid":"https://orcid.org/0000-0002-5407-1555","observed_orcids":["https://orcid.org/0000-0002-5407-1555"]},"institutions":[{"id":"https://openalex.org/I4210142841","display_name":"Chang Gung Children's Hospital","ror":"https://ror.org/054e9ag92","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210142841"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"T.-H. Jaing","raw_affiliation_strings":["Chang Gung Children's Hospital, Linkou, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chang Gung Children's Hospital, Linkou, Taiwan","institution_ids":["https://openalex.org/I4210142841"]}]},{"author_position":"middle","author":{"id":null,"display_name":"L.L. Chan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I33849332","display_name":"University of Malaya","ror":"https://ror.org/00rzspn62","country_code":"MY","type":"education","lineage":["https://openalex.org/I33849332"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"L.L. Chan","raw_affiliation_strings":["University of Malaya, Kuala Lumpar, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Malaya, Kuala Lumpar, Malaysia","institution_ids":["https://openalex.org/I33849332"]}]},{"author_position":"middle","author":{"id":null,"display_name":"P. Tan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800542734","display_name":"Mount Elizabeth Hospital","ror":"https://ror.org/019z9dk17","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2800542734"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"P. Tan","raw_affiliation_strings":["Mount Elizabeth Hospital, Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mount Elizabeth Hospital, Singapore, Singapore","institution_ids":["https://openalex.org/I2800542734"]}]},{"author_position":"middle","author":{"id":null,"display_name":"H.-P. Lin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210147568","display_name":"Subang Jaya Medical Centre","ror":"https://ror.org/05b01nv96","country_code":"MY","type":"healthcare","lineage":["https://openalex.org/I4210147568"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"H.-P. Lin","raw_affiliation_strings":["Subang Jaya Medical Center, Kuala Lumpar, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Subang Jaya Medical Center, Kuala Lumpar, Singapore","institution_ids":["https://openalex.org/I4210147568"]}]},{"author_position":"middle","author":{"id":null,"display_name":"M. Graham","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210108981","display_name":"Banner Thunderbird Medical Center","ror":"https://ror.org/01kqrgb09","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802412784","https://openalex.org/I4210108981"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. Graham","raw_affiliation_strings":["Banner Thunderbird Medical Center, Glendale, AZ"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Banner Thunderbird Medical Center, Glendale, AZ","institution_ids":["https://openalex.org/I4210108981"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071412954","display_name":"Joseph Rosenthal","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1301076528","display_name":"City Of Hope National Medical Center","ror":"https://ror.org/00w6g5w60","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1301076528"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Rosenthal","raw_affiliation_strings":["City of Hope National Medical Center, Duarte, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"City of Hope National Medical Center, Duarte, CA","institution_ids":["https://openalex.org/I1301076528"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033267787","display_name":"Chatchada Karanes","orcid":"https://orcid.org/0009-0001-8099-7802","observed_orcids":["https://orcid.org/0009-0001-8099-7802","https://orcid.org/0000-0002-9535-4981"]},"institutions":[{"id":"https://openalex.org/I1301076528","display_name":"City Of Hope National Medical Center","ror":"https://ror.org/00w6g5w60","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1301076528"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C. Karanes","raw_affiliation_strings":["City of Hope National Medical Center, Duarte, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"City of Hope National Medical Center, Duarte, CA","institution_ids":["https://openalex.org/I1301076528"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112255312","display_name":"Auayporn P. Nademanee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1301076528","display_name":"City Of Hope National Medical Center","ror":"https://ror.org/00w6g5w60","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1301076528"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. Nademanee","raw_affiliation_strings":["City of Hope National Medical Center, Duarte, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"City of Hope National Medical Center, Duarte, CA","institution_ids":["https://openalex.org/I1301076528"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084257078","display_name":"B.C. Wang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B.C. Wang","raw_affiliation_strings":["B.C.W. Statistical Consultants, Los Angeles, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"B.C.W. Statistical Consultants, Los Angeles, CA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072198676","display_name":"Lim Kah Yen","orcid":"https://orcid.org/0009-0005-0315-1642","observed_orcids":["https://orcid.org/0009-0005-0315-1642"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L. Yen","raw_affiliation_strings":["B.C.W. Statistical Consultants, Los Angeles, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"B.C.W. Statistical Consultants, Los Angeles, CA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023303405","display_name":"Michelle Chow","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M.R. Chow","raw_affiliation_strings":["B.C.W. Statistical Consultants, Los Angeles, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"B.C.W. Statistical Consultants, Los Angeles, CA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108429641","display_name":"T. Dang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T. Dang","raw_affiliation_strings":["B.C.W. Statistical Consultants, Los Angeles, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"B.C.W. Statistical Consultants, Los Angeles, CA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060384074","display_name":"Joanne Kurtzberg","orcid":"https://orcid.org/0000-0002-3370-0703","observed_orcids":["https://orcid.org/0000-0002-3370-0703"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Kurtzberg","raw_affiliation_strings":["Duke University Medical Center, Durham, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Duke University Medical Center, Durham, NC","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074941406","display_name":"Lawrence D. Petz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210089186","display_name":"StemCyte","ror":"https://ror.org/00bekwh77","country_code":"US","type":"other","lineage":["https://openalex.org/I4210089186"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L.D. Petz","raw_affiliation_strings":["StemCyte, Inc., Covina, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"StemCyte, Inc., Covina, CA","institution_ids":["https://openalex.org/I4210089186"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":8,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3650,"currency":"USD","value_usd":3650},"apc_paid":{"value":3650,"currency":"USD","value_usd":3650},"fwci":0.2044,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.58057685,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"18","issue":"2","first_page":"S268","last_page":"S268"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10693","display_name":"Blood transfusion and management","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/unrelated-cord-blood-transplantation","display_name":"unrelated cord blood transplantation","score":0.984000027179718},{"id":"https://openalex.org/keywords/hemoglobinopathies","display_name":"hemoglobinopathies","score":0.9620000123977661},{"id":"https://openalex.org/keywords/nucleated-cell-dose","display_name":"nucleated cell dose","score":0.75},{"id":"https://openalex.org/keywords/plasma-depletion","display_name":"plasma depletion","score":0.9100000262260437},{"id":"https://openalex.org/keywords/disease-free-survival","display_name":"disease-free survival","score":0.9169999957084656},{"id":"https://openalex.org/keywords/clinical-outcomes","display_name":"clinical outcomes","score":0.4950000047683716}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8968445062637329},{"id":"https://openalex.org/C2780611847","wikidata":"https://www.wikidata.org/wiki/Q348922","display_name":"Busulfan","level":4,"score":0.7201157808303833},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.6316779255867004},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5171951055526733},{"id":"https://openalex.org/C2777799968","wikidata":"https://www.wikidata.org/wiki/Q185137","display_name":"Thalassemia","level":2,"score":0.49514904618263245},{"id":"https://openalex.org/C2780914630","wikidata":"https://www.wikidata.org/wiki/Q914952","display_name":"Cord blood","level":2,"score":0.472128689289093},{"id":"https://openalex.org/C2779668550","wikidata":"https://www.wikidata.org/wiki/Q1642147","display_name":"Hemoglobinopathy","level":3,"score":0.4476833641529083},{"id":"https://openalex.org/C2777408962","wikidata":"https://www.wikidata.org/wiki/Q1128050","display_name":"Hematopoietic stem cell transplantation","level":3,"score":0.44411903619766235},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.393635630607605},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3429180681705475},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.2807205319404602}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.bbmt.2011.12.529","doi":"https://doi.org/10.1016/j.bbmt.2011.12.529","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbmt.2011.12.529","pdf_url":"http://www.astctjournal.org/article/S1083879111010913/pdf","source":{"id":"https://openalex.org/S59987174","display_name":"Transplantation and Cellular Therapy","issn_l":"1083-8791","issn":["1083-8791","1523-6536","2666-6367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of Blood and Marrow Transplantation","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.bbmt.2011.12.529","doi":"https://doi.org/10.1016/j.bbmt.2011.12.529","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbmt.2011.12.529","pdf_url":"http://www.astctjournal.org/article/S1083879111010913/pdf","source":{"id":"https://openalex.org/S59987174","display_name":"Transplantation and Cellular Therapy","issn_l":"1083-8791","issn":["1083-8791","1523-6536","2666-6367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of Blood and Marrow Transplantation","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2015668790.pdf","grobid_xml":"https://content.openalex.org/works/W2015668790.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2139196789","https://openalex.org/W1690947099","https://openalex.org/W2045169785","https://openalex.org/W2414911773","https://openalex.org/W2592871544","https://openalex.org/W1991920256","https://openalex.org/W2583112587","https://openalex.org/W2144678700","https://openalex.org/W1998327828","https://openalex.org/W4389230727"],"abstract_inverted_index":{"Unrelated":[0],"cord":[1],"blood":[2],"transplantation":[3,25],"(CBT)":[4],"is":[5],"not":[6],"widely":[7],"used":[8,94],"to":[9,62,76],"treat":[10],"hemoglobinopathies":[11],"(HGB)":[12],"despite":[13],"being":[14],"the":[15,50,96,109],"fastest":[16],"growing":[17],"stem":[18],"cell":[19,24,65],"source":[20],"for":[21,53],"unrelated":[22],"hematopoietic":[23],"(HCT).":[26],"Published":[27],"series":[28,104],"show":[29],"unfavorable":[30],"disease-free":[31],"survival":[32],"(Ruggeri":[33],"et":[34,44],"al.":[35,45],"BBMT":[36],"2011)":[37],"or":[38],"were":[39,93],"single":[40,83],"institution":[41],"efforts":[42],"(Jaing":[43],"BMT":[46],"2011).":[47],"We":[48],"analyzed":[49],"clinical":[51],"outcome":[52],"101":[54],"HGB":[55],"patients":[56],"following":[57],"CBT.":[58,110],"The":[59],"combination":[60],"approach":[61],"optimize":[63],"nucleated":[64],"(NC)":[66],"dose":[67],"of":[68,108],"choosing":[69],"CB":[70,84],"products":[71],"manufactured":[72],"by":[73,95],"plasma":[74],"depletion/reduction":[75],"maximize":[77],"NC":[78,87],"recovery,":[79],"double":[80],"grafts":[81],"(whenever":[82],"had":[85],"insufficient":[86],"dose),":[88],"and":[89],"post-thaw":[90],"direct":[91],"infusion":[92],"5":[97],"Asian":[98],"transplant":[99],"centers":[100],"(TCs)":[101],"in":[102],"this":[103],"that":[105],"performed":[106],"most":[107]},"counts_by_year":[{"year":2017,"cited_by_count":2},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}