{"id":"https://openalex.org/W2015643123","doi":"https://doi.org/10.1016/j.ejphar.2006.02.028","title":"Effects of bezafibrate, PPAR pan-agonist, and GW501516, PPAR\u03b4 agonist, on development of steatohepatitis in mice fed a methionine- and choline-deficient diet","display_name":"Effects of bezafibrate, PPAR pan-agonist, and GW501516, PPAR\u03b4 agonist, on development of steatohepatitis in mice fed a methionine- and choline-deficient diet","publication_year":2006,"publication_date":"2006-03-01","ids":{"openalex":"https://openalex.org/W2015643123","doi":"https://doi.org/10.1016/j.ejphar.2006.02.028","mag":"2015643123","pmid":"https://pubmed.ncbi.nlm.nih.gov/16574099"},"language":"en","primary_location":{"id":"doi:10.1016/j.ejphar.2006.02.028","doi":"https://doi.org/10.1016/j.ejphar.2006.02.028","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ejphar.2006.02.028","pdf_url":null,"source":{"id":"https://openalex.org/S187816532","display_name":"European Journal of Pharmacology","issn_l":"0014-2999","issn":["0014-2999","1879-0712"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Pharmacology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Tatsuya Nagasawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119256","display_name":"Kissei Pharmaceutical (Japan)","ror":"https://ror.org/028gkfr23","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210119256"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Tatsuya Nagasawa","raw_affiliation_strings":["Toxicology Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., 2320-1 Maki, Hotaka, Azumino-city, Nagano-Pref., 399-8305, Japan. tatsuya_nagasawa@pharm.kissei.co.jp","Toxicology Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., 2320-1 Maki, Hotaka, Azumino-city, Nagano-Pref., 399-8305, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Toxicology Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., 2320-1 Maki, Hotaka, Azumino-city, Nagano-Pref., 399-8305, Japan. tatsuya_nagasawa@pharm.kissei.co.jp","institution_ids":["https://openalex.org/I4210119256"]},{"raw_affiliation_string":"Toxicology Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., 2320-1 Maki, Hotaka, Azumino-city, Nagano-Pref., 399-8305, Japan","institution_ids":["https://openalex.org/I4210119256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042671058","display_name":"Yoichi Inada","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119256","display_name":"Kissei Pharmaceutical (Japan)","ror":"https://ror.org/028gkfr23","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210119256"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoichi Inada","raw_affiliation_strings":["Pharmacology Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmacology Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., Japan","institution_ids":["https://openalex.org/I4210119256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041464056","display_name":"Shigeru Nakano","orcid":"https://orcid.org/0000-0001-5345-8232","observed_orcids":["https://orcid.org/0000-0001-5345-8232"]},"institutions":[{"id":"https://openalex.org/I4210119256","display_name":"Kissei Pharmaceutical (Japan)","ror":"https://ror.org/028gkfr23","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210119256"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shigeru Nakano","raw_affiliation_strings":["Pharmacology Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmacology Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., Japan","institution_ids":["https://openalex.org/I4210119256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048625194","display_name":"Toru Tamura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119256","display_name":"Kissei Pharmaceutical (Japan)","ror":"https://ror.org/028gkfr23","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210119256"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toru Tamura","raw_affiliation_strings":["Toxicology Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., 2320-1 Maki, Hotaka, Azumino-city, Nagano-Pref., 399-8305, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Toxicology Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., 2320-1 Maki, Hotaka, Azumino-city, Nagano-Pref., 399-8305, Japan","institution_ids":["https://openalex.org/I4210119256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067247179","display_name":"Tetsuaki Takahashi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119256","display_name":"Kissei Pharmaceutical (Japan)","ror":"https://ror.org/028gkfr23","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210119256"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tetsuaki Takahashi","raw_affiliation_strings":["Research and Development Planning Department, Kissei Pharmaceutical Co., Ltd., Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research and Development Planning Department, Kissei Pharmaceutical Co., Ltd., Japan","institution_ids":["https://openalex.org/I4210119256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111885419","display_name":"Kazuyasu Maruyama","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119256","display_name":"Kissei Pharmaceutical (Japan)","ror":"https://ror.org/028gkfr23","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210119256"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazuyasu Maruyama","raw_affiliation_strings":["Pharmacology Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmacology Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., Japan","institution_ids":["https://openalex.org/I4210119256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067697148","display_name":"Yoshinobu Yamazaki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119256","display_name":"Kissei Pharmaceutical (Japan)","ror":"https://ror.org/028gkfr23","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210119256"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshinobu Yamazaki","raw_affiliation_strings":["Pharmacology Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmacology Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., Japan","institution_ids":["https://openalex.org/I4210119256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080735724","display_name":"Junji Kuroda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119256","display_name":"Kissei Pharmaceutical (Japan)","ror":"https://ror.org/028gkfr23","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210119256"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Junji Kuroda","raw_affiliation_strings":["Toxicology Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., 2320-1 Maki, Hotaka, Azumino-city, Nagano-Pref., 399-8305, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Toxicology Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., 2320-1 Maki, Hotaka, Azumino-city, Nagano-Pref., 399-8305, Japan","institution_ids":["https://openalex.org/I4210119256"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113767688","display_name":"Nobuo Shibata","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119256","display_name":"Kissei Pharmaceutical (Japan)","ror":"https://ror.org/028gkfr23","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210119256"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Nobuo Shibata","raw_affiliation_strings":["Development Research Department, R&D, Kissei Pharmaceutical Co., Ltd., Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Development Research Department, R&D, Kissei Pharmaceutical Co., Ltd., Japan","institution_ids":["https://openalex.org/I4210119256"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210119256"],"apc_list":{"value":3230,"currency":"USD","value_usd":3230},"apc_paid":null,"fwci":13.3916,"has_fulltext":false,"cited_by_count":239,"citation_normalized_percentile":{"value":0.99045844,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":100},"biblio":{"volume":"536","issue":"1-2","first_page":"182","last_page":"191"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.8817999958992004,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.8817999958992004,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11072","display_name":"Peroxisome Proliferator-Activated Receptors","score":0.11180000007152557,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11465","display_name":"Drug-Induced Hepatotoxicity and Protection","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bezafibrate","display_name":"bezafibrate","score":0.996999979019165},{"id":"https://openalex.org/keywords/gw501516","display_name":"GW501516","score":0.9729999899864197},{"id":"https://openalex.org/keywords/ppardelta-agonist","display_name":"PPAR\u03b4 agonist","score":0.7739999890327454},{"id":"https://openalex.org/keywords/non-alcoholic-steatohepatitis","display_name":"nonalcoholic steatohepatitis","score":0.9900000095367432},{"id":"https://openalex.org/keywords/methionine-and-choline-deficient-diet","display_name":"methionine-choline-deficient diet","score":0.9610000252723694},{"id":"https://openalex.org/keywords/hepatic-steatosis","display_name":"hepatic steatosis","score":0.8849999904632568},{"id":"https://openalex.org/keywords/fatty-acid-beta-oxidation","display_name":"fatty acid beta-oxidation","score":0.9110000133514404},{"id":"https://openalex.org/keywords/liver-inflammation","display_name":"liver inflammation","score":0.7549999952316284},{"id":"https://openalex.org/keywords/adiponectin","display_name":"adiponectin","score":0.8069999814033508},{"id":"https://openalex.org/keywords/adiponectin-receptors","display_name":"adiponectin receptors","score":0.8299999833106995},{"id":"https://openalex.org/keywords/hepatic-stellate-cells","display_name":"hepatic stellate cells","score":0.8510000109672546}],"concepts":[{"id":"https://openalex.org/C2776362216","wikidata":"https://www.wikidata.org/wiki/Q577387","display_name":"Bezafibrate","level":2,"score":0.9343991875648499},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.8086565732955933},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7912052273750305},{"id":"https://openalex.org/C2779478299","wikidata":"https://www.wikidata.org/wiki/Q2335423","display_name":"Steatohepatitis","level":4,"score":0.7031747698783875},{"id":"https://openalex.org/C2778938600","wikidata":"https://www.wikidata.org/wiki/Q389934","display_name":"Agonist","level":3,"score":0.4857380986213684},{"id":"https://openalex.org/C2776782570","wikidata":"https://www.wikidata.org/wiki/Q357439","display_name":"Adiponectin","level":4,"score":0.4841249883174896},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4629695415496826},{"id":"https://openalex.org/C2778772119","wikidata":"https://www.wikidata.org/wiki/Q6058862","display_name":"Fatty liver","level":3,"score":0.4432864487171173},{"id":"https://openalex.org/C187345961","wikidata":"https://www.wikidata.org/wiki/Q419629","display_name":"Peroxisome proliferator-activated receptor","level":3,"score":0.4350167214870453},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.33980751037597656},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.3314237594604492},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.14179691672325134},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.1207762360572815},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000410","descriptor_name":"Alanine Transaminase","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001629","descriptor_name":"Bezafibrate","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D001629","descriptor_name":"Bezafibrate","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D002334","descriptor_name":"Carnitine O-Palmitoyltransferase","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002794","descriptor_name":"Choline","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D004032","descriptor_name":"Diet","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005234","descriptor_name":"Fatty Liver","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D005234","descriptor_name":"Fatty Liver","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D005234","descriptor_name":"Fatty Liver","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D008076","descriptor_name":"Cholesterol, HDL","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008715","descriptor_name":"Methionine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013844","descriptor_name":"Thiazoles","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D013844","descriptor_name":"Thiazoles","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D014280","descriptor_name":"Triglycerides","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D014280","descriptor_name":"Triglycerides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015850","descriptor_name":"Interleukin-6","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D016212","descriptor_name":"Transforming Growth Factor beta","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017392","descriptor_name":"Thiobarbituric Acid Reactive Substances","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D042962","descriptor_name":"Acyl-CoA Oxidase","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D047492","descriptor_name":"Peroxisome Proliferator-Activated Receptors","qualifier_ui":"Q000819","qualifier_name":"agonists","is_major_topic":false},{"descriptor_ui":"D047494","descriptor_name":"PPAR delta","qualifier_ui":"Q000819","qualifier_name":"agonists","is_major_topic":false},{"descriptor_ui":"D050556","descriptor_name":"Fatty Acid-Binding Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053773","descriptor_name":"Transforming Growth Factor beta1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.ejphar.2006.02.028","doi":"https://doi.org/10.1016/j.ejphar.2006.02.028","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ejphar.2006.02.028","pdf_url":null,"source":{"id":"https://openalex.org/S187816532","display_name":"European Journal of Pharmacology","issn_l":"0014-2999","issn":["0014-2999","1879-0712"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Pharmacology","raw_type":"journal-article"},{"id":"pmid:16574099","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16574099","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of pharmacology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":44,"referenced_works":["https://openalex.org/W57656366","https://openalex.org/W195155228","https://openalex.org/W1528321309","https://openalex.org/W1557678369","https://openalex.org/W1830680247","https://openalex.org/W1963533730","https://openalex.org/W1970113978","https://openalex.org/W1971452427","https://openalex.org/W1977666051","https://openalex.org/W1982027543","https://openalex.org/W1983346696","https://openalex.org/W1983417944","https://openalex.org/W1988524962","https://openalex.org/W1989107036","https://openalex.org/W1994710410","https://openalex.org/W1997978122","https://openalex.org/W2000863347","https://openalex.org/W2006591225","https://openalex.org/W2007733439","https://openalex.org/W2017671227","https://openalex.org/W2042706232","https://openalex.org/W2047309793","https://openalex.org/W2051987387","https://openalex.org/W2053026149","https://openalex.org/W2058709707","https://openalex.org/W2080361134","https://openalex.org/W2080945617","https://openalex.org/W2096346573","https://openalex.org/W2097706636","https://openalex.org/W2099356672","https://openalex.org/W2106965601","https://openalex.org/W2108971238","https://openalex.org/W2111505871","https://openalex.org/W2112377527","https://openalex.org/W2144178804","https://openalex.org/W2144829836","https://openalex.org/W2144834841","https://openalex.org/W2156019168","https://openalex.org/W2168526937","https://openalex.org/W2400712338","https://openalex.org/W3149847267","https://openalex.org/W4243729710","https://openalex.org/W6631509062","https://openalex.org/W6979149479"],"related_works":["https://openalex.org/W4226518179","https://openalex.org/W2077294661","https://openalex.org/W3021692931","https://openalex.org/W2944337921","https://openalex.org/W3043312299","https://openalex.org/W2083685463","https://openalex.org/W2381067325","https://openalex.org/W2062229082","https://openalex.org/W2110663976","https://openalex.org/W186082925"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":16},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":15},{"year":2015,"cited_by_count":14},{"year":2014,"cited_by_count":14},{"year":2013,"cited_by_count":19},{"year":2012,"cited_by_count":14}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}