{"id":"https://openalex.org/W2015642943","doi":"https://doi.org/10.1088/1741-2560/2/1/009","title":"Long-term stimulation by active epiretinal implants in normal and RCD1 dogs","display_name":"Long-term stimulation by active epiretinal implants in normal and RCD1 dogs","publication_year":2005,"publication_date":"2005-02-23","ids":{"openalex":"https://openalex.org/W2015642943","doi":"https://doi.org/10.1088/1741-2560/2/1/009","mag":"2015642943","pmid":"https://pubmed.ncbi.nlm.nih.gov/15876657"},"language":"en","primary_location":{"id":"doi:10.1088/1741-2560/2/1/009","doi":"https://doi.org/10.1088/1741-2560/2/1/009","is_oa":true,"landing_page_url":"https://doi.org/10.1088/1741-2560/2/1/009","pdf_url":"https://iopscience.iop.org/article/10.1088/1741-2560/2/1/009/pdf","source":{"id":"https://openalex.org/S32898093","display_name":"Journal of Neural Engineering","issn_l":"1741-2552","issn":["1741-2552","1741-2560"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320083","host_organization_name":"IOP Publishing","host_organization_lineage":["https://openalex.org/P4310320083","https://openalex.org/P4310311669"],"host_organization_lineage_names":["IOP Publishing","Institute of Physics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neural Engineering","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://iopscience.iop.org/article/10.1088/1741-2560/2/1/009/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034440100","display_name":"Dilek G\u00fcven","orcid":"https://orcid.org/0000-0002-1606-9075","observed_orcids":["https://orcid.org/0000-0002-1606-9075"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I4210095445","display_name":"Doheny Eye Institute","ror":"https://ror.org/00qvx5329","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210095445"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dilek G\u00fcven","raw_affiliation_strings":["Doheny Retina Institute, Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Doheny Retina Institute, Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I4210095445"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089711083","display_name":"James David Weiland","orcid":"https://orcid.org/0000-0003-3453-9074","observed_orcids":["https://orcid.org/0000-0003-3453-9074"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I4210095445","display_name":"Doheny Eye Institute","ror":"https://ror.org/00qvx5329","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210095445"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James D Weiland","raw_affiliation_strings":["Doheny Retina Institute, Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Doheny Retina Institute, Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I4210095445"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109285761","display_name":"Gildo Y Fujii","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I4210095445","display_name":"Doheny Eye Institute","ror":"https://ror.org/00qvx5329","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210095445"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gildo Fujii","raw_affiliation_strings":["Doheny Retina Institute, Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Doheny Retina Institute, Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I4210095445"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110024928","display_name":"B.V. Mech","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210098952","display_name":"Second Sight Medical Products","ror":"https://ror.org/0146tx053","country_code":"US","type":"company","lineage":["https://openalex.org/I4210098952"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brian V Mech","raw_affiliation_strings":["Second Sight Medical Products, Inc., Sylmar, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Second Sight Medical Products, Inc., Sylmar, CA, USA","institution_ids":["https://openalex.org/I4210098952"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044064329","display_name":"Manjunatha Mahadevappa","orcid":"https://orcid.org/0000-0003-4700-9080","observed_orcids":["https://orcid.org/0000-0003-4700-9080"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I4210095445","display_name":"Doheny Eye Institute","ror":"https://ror.org/00qvx5329","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210095445"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Manjunatha Mahadevappa","raw_affiliation_strings":["Doheny Retina Institute, Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Doheny Retina Institute, Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I4210095445"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111389908","display_name":"Robert J. Greenberg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I4210095445","display_name":"Doheny Eye Institute","ror":"https://ror.org/00qvx5329","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210095445"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert Greenberg","raw_affiliation_strings":["Doheny Retina Institute, Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Doheny Retina Institute, Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I4210095445"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066280580","display_name":"Roberto Roizenblatt","orcid":"https://orcid.org/0000-0001-8291-7303","observed_orcids":["https://orcid.org/0000-0001-8291-7303"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I4210095445","display_name":"Doheny Eye Institute","ror":"https://ror.org/00qvx5329","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210095445"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Roberto Roizenblatt","raw_affiliation_strings":["Doheny Retina Institute, Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Doheny Retina Institute, Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I4210095445"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103678358","display_name":"Guanting Qiu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I4210095445","display_name":"Doheny Eye Institute","ror":"https://ror.org/00qvx5329","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210095445"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Guanting Qiu","raw_affiliation_strings":["Doheny Retina Institute, Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Doheny Retina Institute, Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I4210095445"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110168307","display_name":"LAURIE D. LABREE","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laurie LaBree","raw_affiliation_strings":["Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Xiaopeng Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I4210095445","display_name":"Doheny Eye Institute","ror":"https://ror.org/00qvx5329","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210095445"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiaopeng Wang","raw_affiliation_strings":["Doheny Retina Institute, Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Doheny Retina Institute, Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I4210095445"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051011191","display_name":"David R. Hinton","orcid":"https://orcid.org/0000-0002-3971-8891","observed_orcids":["https://orcid.org/0000-0002-3971-8891"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I4210095445","display_name":"Doheny Eye Institute","ror":"https://ror.org/00qvx5329","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210095445"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David Hinton","raw_affiliation_strings":["Doheny Retina Institute, Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Doheny Retina Institute, Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I4210095445"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052140640","display_name":"Mark S. Humayun","orcid":"https://orcid.org/0000-0002-5830-5208","observed_orcids":["https://orcid.org/0000-0002-5830-5208"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I4210095445","display_name":"Doheny Eye Institute","ror":"https://ror.org/00qvx5329","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210095445"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark S Humayun","raw_affiliation_strings":["Doheny Retina Institute, Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Doheny Retina Institute, Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I4210095445"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3325,"currency":"USD","value_usd":3325},"apc_paid":null,"fwci":2.9,"has_fulltext":true,"cited_by_count":70,"citation_normalized_percentile":{"value":0.91197013,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"2","issue":"1","first_page":"S65","last_page":"S73"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11840","display_name":"Pain Management and Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/epiretinal-prosthesis","display_name":"epiretinal prosthesis","score":0.9909999966621399},{"id":"https://openalex.org/keywords/retinitis-pigmentosa","display_name":"retinitis pigmentosa","score":0.6940000057220459},{"id":"https://openalex.org/keywords/chronic-electrical-stimulation","display_name":"chronic electrical stimulation","score":0.8859999775886536},{"id":"https://openalex.org/keywords/retinal-histology","display_name":"retinal histology","score":0.7360000014305115},{"id":"https://openalex.org/keywords/retinal-morphometry","display_name":"retinal morphometry","score":0.9570000171661377},{"id":"https://openalex.org/keywords/electroretinography","display_name":"electroretinogram","score":0.921999990940094},{"id":"https://openalex.org/keywords/retinal-safety","display_name":"retinal safety","score":0.4659999907016754},{"id":"https://openalex.org/keywords/canine-model","display_name":"canine model","score":0.35899999737739563}],"concepts":[{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.7345799803733826},{"id":"https://openalex.org/C2777093970","wikidata":"https://www.wikidata.org/wiki/Q169342","display_name":"Retina","level":2,"score":0.7163009643554688},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.6459739804267883},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5984487533569336},{"id":"https://openalex.org/C2779918689","wikidata":"https://www.wikidata.org/wiki/Q3771842","display_name":"Stimulus (psychology)","level":2,"score":0.5956705808639526},{"id":"https://openalex.org/C2781411149","wikidata":"https://www.wikidata.org/wiki/Q486975","display_name":"Implant","level":2,"score":0.5866613388061523},{"id":"https://openalex.org/C154145042","wikidata":"https://www.wikidata.org/wiki/Q1072103","display_name":"Phosphene","level":4,"score":0.5448782444000244},{"id":"https://openalex.org/C2779113765","wikidata":"https://www.wikidata.org/wiki/Q681562","display_name":"Electroretinography","level":3,"score":0.5059203505516052},{"id":"https://openalex.org/C2778715743","wikidata":"https://www.wikidata.org/wiki/Q181802","display_name":"Prosthesis","level":2,"score":0.4679758846759796},{"id":"https://openalex.org/C2776391266","wikidata":"https://www.wikidata.org/wiki/Q9612","display_name":"Fundus (uterus)","level":2,"score":0.44770342111587524},{"id":"https://openalex.org/C2778560042","wikidata":"https://www.wikidata.org/wiki/Q540043","display_name":"Visual prosthesis","level":3,"score":0.44200485944747925},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.3690356910228729},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.3302138149738312},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.25895851850509644},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.15355607867240906},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.1401505172252655},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.13155701756477356},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.12358567118644714},{"id":"https://openalex.org/C542102704","wikidata":"https://www.wikidata.org/wiki/Q183257","display_name":"Psychotherapist","level":1,"score":0.0},{"id":"https://openalex.org/C2778581513","wikidata":"https://www.wikidata.org/wiki/Q263962","display_name":"Transcranial magnetic stimulation","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004558","descriptor_name":"Electric Stimulation","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D004558","descriptor_name":"Electric Stimulation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D004567","descriptor_name":"Electrodes, Implanted","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D005549","descriptor_name":"Foreign-Body Reaction","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D005549","descriptor_name":"Foreign-Body Reaction","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008839","descriptor_name":"Microelectrodes","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D012160","descriptor_name":"Retina","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D012160","descriptor_name":"Retina","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D012160","descriptor_name":"Retina","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D012162","descriptor_name":"Retinal Degeneration","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D012162","descriptor_name":"Retinal Degeneration","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D012162","descriptor_name":"Retinal Degeneration","qualifier_ui":"Q000534","qualifier_name":"rehabilitation","is_major_topic":false},{"descriptor_ui":"D012162","descriptor_name":"Retinal Degeneration","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019736","descriptor_name":"Prostheses and Implants","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1088/1741-2560/2/1/009","doi":"https://doi.org/10.1088/1741-2560/2/1/009","is_oa":true,"landing_page_url":"https://doi.org/10.1088/1741-2560/2/1/009","pdf_url":"https://iopscience.iop.org/article/10.1088/1741-2560/2/1/009/pdf","source":{"id":"https://openalex.org/S32898093","display_name":"Journal of Neural Engineering","issn_l":"1741-2552","issn":["1741-2552","1741-2560"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320083","host_organization_name":"IOP Publishing","host_organization_lineage":["https://openalex.org/P4310320083","https://openalex.org/P4310311669"],"host_organization_lineage_names":["IOP Publishing","Institute of Physics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neural Engineering","raw_type":"journal-article"},{"id":"pmid:15876657","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15876657","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of neural engineering","raw_type":"Comparative Study"}],"best_oa_location":{"id":"doi:10.1088/1741-2560/2/1/009","doi":"https://doi.org/10.1088/1741-2560/2/1/009","is_oa":true,"landing_page_url":"https://doi.org/10.1088/1741-2560/2/1/009","pdf_url":"https://iopscience.iop.org/article/10.1088/1741-2560/2/1/009/pdf","source":{"id":"https://openalex.org/S32898093","display_name":"Journal of Neural Engineering","issn_l":"1741-2552","issn":["1741-2552","1741-2560"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320083","host_organization_name":"IOP Publishing","host_organization_lineage":["https://openalex.org/P4310320083","https://openalex.org/P4310311669"],"host_organization_lineage_names":["IOP Publishing","Institute of Physics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neural Engineering","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1396024002","display_name":"Core Grant for Vision Research","funder_award_id":"P30EY003040","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G2354109","display_name":"DEVELOPMENT/TESTING OF ARTIFICIAL RETINAS FOR THE BLIND","funder_award_id":"R24EY012893","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"}],"funders":[{"id":"https://openalex.org/F4320310166","display_name":"Fletcher Jones Foundation","ror":"https://ror.org/01p0fnz19"},{"id":"https://openalex.org/F4320337350","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2015642943.pdf","grobid_xml":"https://content.openalex.org/works/W2015642943.grobid-xml"},"referenced_works_count":31,"referenced_works":["https://openalex.org/W78491297","https://openalex.org/W1180789151","https://openalex.org/W1967274843","https://openalex.org/W1974423604","https://openalex.org/W1981894437","https://openalex.org/W1988750763","https://openalex.org/W1992625034","https://openalex.org/W1992665103","https://openalex.org/W2003142190","https://openalex.org/W2013089574","https://openalex.org/W2019087770","https://openalex.org/W2021525350","https://openalex.org/W2021814062","https://openalex.org/W2035290313","https://openalex.org/W2051923857","https://openalex.org/W2055355143","https://openalex.org/W2061347235","https://openalex.org/W2068512926","https://openalex.org/W2070162220","https://openalex.org/W2070268814","https://openalex.org/W2080617193","https://openalex.org/W2081340386","https://openalex.org/W2104175189","https://openalex.org/W2128281026","https://openalex.org/W2155370986","https://openalex.org/W2157054973","https://openalex.org/W2160326715","https://openalex.org/W2409648049","https://openalex.org/W2419500103","https://openalex.org/W4237379092","https://openalex.org/W4409137618"],"related_works":["https://openalex.org/W1525452550","https://openalex.org/W2157054973","https://openalex.org/W1536616650","https://openalex.org/W2057301087","https://openalex.org/W2006635508","https://openalex.org/W2024239655","https://openalex.org/W1192644518","https://openalex.org/W2042391455","https://openalex.org/W7100824561","https://openalex.org/W3175275739"],"abstract_inverted_index":{"An":[0],"epiretinal":[1,189],"prosthesis,":[2],"consisting":[3],"of":[4,19,53,68,95,110,132,177],"an":[5,10,77,188],"extraocular":[6],"microelectronic":[7],"stimulator":[8],"and":[9,22,37,44,57,87,103,105],"intraocular":[11],"electrode":[12],"array,":[13],"was":[14,74,108,119],"implanted":[15],"in":[16,148],"one":[17],"eye":[18],"three":[20,23],"blind":[21,72],"sighted":[24],"dogs.":[25],"Three":[26],"dogs":[27,39,100],"(2":[28],"blind,":[29],"1":[30],"normal)":[31,41],"were":[32,90,101,126,131],"stimulated":[33],"for":[34,42,48],"120":[35],"days,":[36],"two":[38],"(both":[40],"60":[43],"103":[45],"days":[46],"respectively":[47],"8-10":[49],"h/day":[50],"at":[51,181],"levels":[52,129],"0.1":[54,184],"mC":[55,59,185],"cm(-2)":[56,186],"0.05":[58],"cm(-2),":[60],"with":[61,187],"each":[62],"stimulus":[63],"level":[64],"presented":[65],"to":[66,135,152,157,169,183,194],"half":[67],"the":[69,82,93,96,99,111,122,158,178,197],"array.":[70],"One":[71],"dog":[73,179],"kept":[75],"as":[76],"inactive":[78],"implant":[79],"control.":[80],"During":[81],"study":[83,97],"period,":[84,98],"electroretinograms":[85],"(ERG)":[86],"fundus":[88],"photographs":[89],"recorded.":[91],"At":[92],"end":[94],"sacrificed":[102],"histological":[104],"morphometric":[106],"evaluation":[107,141],"made":[109],"retina.":[112,198],"No":[113],"inflammatory":[114,144],"reaction,":[115],"neovascularization":[116],"or":[117,146],"hemorrhage":[118],"observed":[120],"during":[121],"follow-up":[123],"examinations.":[124],"ERGs":[125],"unchanged.":[127],"Stimulus":[128],"used":[130],"sufficient":[133],"amplitude":[134],"elicit":[136],"cortical":[137],"evoked":[138],"potentials.":[139],"Histological":[140],"showed":[142],"no":[143,165],"infiltrates":[145],"changes":[147],"retina":[149,180],"morphometry":[150],"related":[151],"electrical":[153,170,175],"stimulation":[154,176],"when":[155],"compared":[156],"unstimulated":[159],"control":[160],"eye.":[161],"Morphometric":[162],"analysis":[163],"revealed":[164],"consistent":[166],"differences":[167],"relating":[168],"stimulation.":[171],"In":[172],"summary,":[173],"chronic":[174],"up":[182],"prosthesis":[190],"does":[191],"not":[192],"appear":[193],"adversely":[195],"affect":[196]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":3}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}