{"id":"https://openalex.org/W2015607254","doi":"https://doi.org/10.1016/j.vaccine.2011.10.098","title":"Vaccination with NS1-truncated H3N2 swine influenza virus primes T cells and confers cross-protection against an H1N1 heterosubtypic challenge in pigs","display_name":"Vaccination with NS1-truncated H3N2 swine influenza virus primes T cells and confers cross-protection against an H1N1 heterosubtypic challenge in pigs","publication_year":2011,"publication_date":"2011-11-07","ids":{"openalex":"https://openalex.org/W2015607254","doi":"https://doi.org/10.1016/j.vaccine.2011.10.098","mag":"2015607254","pmid":"https://pubmed.ncbi.nlm.nih.gov/22067263"},"language":"en","primary_location":{"id":"doi:10.1016/j.vaccine.2011.10.098","doi":"https://doi.org/10.1016/j.vaccine.2011.10.098","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.vaccine.2011.10.098","pdf_url":null,"source":{"id":"https://openalex.org/S27359860","display_name":"Vaccine","issn_l":"0264-410X","issn":["0264-410X","1873-2518"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vaccine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036785126","display_name":"Matthew Allan Kappes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1312222531","display_name":"Agricultural Research Service","ror":"https://ror.org/02d2m2044","country_code":"US","type":"government","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I1336096307","display_name":"United States Department of Agriculture","ror":"https://ror.org/01na82s61","country_code":"US","type":"government","lineage":["https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I4210142913","display_name":"National Animal Disease Center","ror":"https://ror.org/04ky99h94","country_code":"US","type":"facility","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210142913","https://openalex.org/I4210154632"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthew A. Kappes","raw_affiliation_strings":["Virus and Prion Diseases Research Unit, National Animal Disease Center, USDA-ARS, 1920 Dayton Ave, PO Box 70, Ames, IA 50010, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Virus and Prion Diseases Research Unit, National Animal Disease Center, USDA-ARS, 1920 Dayton Ave, PO Box 70, Ames, IA 50010, USA","institution_ids":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210142913"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082756282","display_name":"Matthew R. Sandbulte","orcid":"https://orcid.org/0000-0001-6693-674X","observed_orcids":["https://orcid.org/0000-0001-6693-674X"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthew R. Sandbulte","raw_affiliation_strings":["Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA, USA","Department of Veterinary Microbiology & Preventive Medicine, Iowa State University, Ames, IA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA, USA","institution_ids":["https://openalex.org/I173911158"]},{"raw_affiliation_string":"Department of Veterinary Microbiology & Preventive Medicine, Iowa State University, Ames, IA, USA","institution_ids":["https://openalex.org/I173911158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003857661","display_name":"Ratree Platt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ratree Platt","raw_affiliation_strings":["Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA, USA","Department of Veterinary Microbiology & Preventive Medicine, Iowa State University, Ames, IA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA, USA","institution_ids":["https://openalex.org/I173911158"]},{"raw_affiliation_string":"Department of Veterinary Microbiology & Preventive Medicine, Iowa State University, Ames, IA, USA","institution_ids":["https://openalex.org/I173911158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100329473","display_name":"Chong Wang","orcid":"https://orcid.org/0000-0003-4489-4344","observed_orcids":["https://orcid.org/0000-0003-4489-4344"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chong Wang","raw_affiliation_strings":["Department of Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA, USA","Department of Veterinary Diagnostic & Production Animal Medicine, Iowa State University, Ames, IA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA, USA","institution_ids":["https://openalex.org/I173911158"]},{"raw_affiliation_string":"Department of Veterinary Diagnostic & Production Animal Medicine, Iowa State University, Ames, IA, USA","institution_ids":["https://openalex.org/I173911158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054597701","display_name":"Kelly Milton Lager","orcid":"https://orcid.org/0000-0001-5328-2337","observed_orcids":["https://orcid.org/0000-0001-5328-2337"]},"institutions":[{"id":"https://openalex.org/I1312222531","display_name":"Agricultural Research Service","ror":"https://ror.org/02d2m2044","country_code":"US","type":"government","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I1336096307","display_name":"United States Department of Agriculture","ror":"https://ror.org/01na82s61","country_code":"US","type":"government","lineage":["https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I4210142913","display_name":"National Animal Disease Center","ror":"https://ror.org/04ky99h94","country_code":"US","type":"facility","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210142913","https://openalex.org/I4210154632"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kelly M. Lager","raw_affiliation_strings":["Virus and Prion Diseases Research Unit, National Animal Disease Center, USDA-ARS, 1920 Dayton Ave, PO Box 70, Ames, IA 50010, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Virus and Prion Diseases Research Unit, National Animal Disease Center, USDA-ARS, 1920 Dayton Ave, PO Box 70, Ames, IA 50010, USA","institution_ids":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210142913"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048733866","display_name":"Jamie N. Henningson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1312222531","display_name":"Agricultural Research Service","ror":"https://ror.org/02d2m2044","country_code":"US","type":"government","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I1336096307","display_name":"United States Department of Agriculture","ror":"https://ror.org/01na82s61","country_code":"US","type":"government","lineage":["https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I4210142913","display_name":"National Animal Disease Center","ror":"https://ror.org/04ky99h94","country_code":"US","type":"facility","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210142913","https://openalex.org/I4210154632"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jamie N. Henningson","raw_affiliation_strings":["Virus and Prion Diseases Research Unit, National Animal Disease Center, USDA-ARS, 1920 Dayton Ave, PO Box 70, Ames, IA 50010, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Virus and Prion Diseases Research Unit, National Animal Disease Center, USDA-ARS, 1920 Dayton Ave, PO Box 70, Ames, IA 50010, USA","institution_ids":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210142913"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022066585","display_name":"Alessio Lorusso","orcid":"https://orcid.org/0000-0001-6156-8212","observed_orcids":["https://orcid.org/0000-0001-6156-8212"]},"institutions":[{"id":"https://openalex.org/I1312222531","display_name":"Agricultural Research Service","ror":"https://ror.org/02d2m2044","country_code":"US","type":"government","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I1336096307","display_name":"United States Department of Agriculture","ror":"https://ror.org/01na82s61","country_code":"US","type":"government","lineage":["https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I4210142913","display_name":"National Animal Disease Center","ror":"https://ror.org/04ky99h94","country_code":"US","type":"facility","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210142913","https://openalex.org/I4210154632"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alessio Lorusso","raw_affiliation_strings":["Virus and Prion Diseases Research Unit, National Animal Disease Center, USDA-ARS, 1920 Dayton Ave, PO Box 70, Ames, IA 50010, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Virus and Prion Diseases Research Unit, National Animal Disease Center, USDA-ARS, 1920 Dayton Ave, PO Box 70, Ames, IA 50010, USA","institution_ids":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210142913"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110095531","display_name":"Amy Louise Vincent","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1312222531","display_name":"Agricultural Research Service","ror":"https://ror.org/02d2m2044","country_code":"US","type":"government","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I1336096307","display_name":"United States Department of Agriculture","ror":"https://ror.org/01na82s61","country_code":"US","type":"government","lineage":["https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I4210142913","display_name":"National Animal Disease Center","ror":"https://ror.org/04ky99h94","country_code":"US","type":"facility","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210142913","https://openalex.org/I4210154632"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amy L. Vincent","raw_affiliation_strings":["Virus and Prion Diseases Research Unit, National Animal Disease Center, USDA-ARS, 1920 Dayton Ave, PO Box 70, Ames, IA 50010, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Virus and Prion Diseases Research Unit, National Animal Disease Center, USDA-ARS, 1920 Dayton Ave, PO Box 70, Ames, IA 50010, USA","institution_ids":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210142913"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110482539","display_name":"Crystal Lynn Loving","orcid":"https://orcid.org/0000-0002-2996-0334","observed_orcids":["https://orcid.org/0000-0002-2996-0334"]},"institutions":[{"id":"https://openalex.org/I1312222531","display_name":"Agricultural Research Service","ror":"https://ror.org/02d2m2044","country_code":"US","type":"government","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I1336096307","display_name":"United States Department of Agriculture","ror":"https://ror.org/01na82s61","country_code":"US","type":"government","lineage":["https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I4210142913","display_name":"National Animal Disease Center","ror":"https://ror.org/04ky99h94","country_code":"US","type":"facility","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210142913","https://openalex.org/I4210154632"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Crystal L. Loving","raw_affiliation_strings":["Virus and Prion Diseases Research Unit, National Animal Disease Center, USDA-ARS, 1920 Dayton Ave, PO Box 70, Ames, IA 50010, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Virus and Prion Diseases Research Unit, National Animal Disease Center, USDA-ARS, 1920 Dayton Ave, PO Box 70, Ames, IA 50010, USA","institution_ids":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210142913"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043298435","display_name":"James A. Roth","orcid":"https://orcid.org/0000-0003-3562-668X","observed_orcids":["https://orcid.org/0000-0003-3562-668X"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James A. Roth","raw_affiliation_strings":["Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA, USA","Department of Veterinary Microbiology & Preventive Medicine, Iowa State University, Ames, IA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA, USA","institution_ids":["https://openalex.org/I173911158"]},{"raw_affiliation_string":"Department of Veterinary Microbiology & Preventive Medicine, Iowa State University, Ames, IA, USA","institution_ids":["https://openalex.org/I173911158"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5053576640","display_name":"Marcus Eugene Kehrli","orcid":"https://orcid.org/0000-0003-4850-5211","observed_orcids":["https://orcid.org/0000-0003-4850-5211"]},"institutions":[{"id":"https://openalex.org/I1312222531","display_name":"Agricultural Research Service","ror":"https://ror.org/02d2m2044","country_code":"US","type":"government","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I1336096307","display_name":"United States Department of Agriculture","ror":"https://ror.org/01na82s61","country_code":"US","type":"government","lineage":["https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I4210142913","display_name":"National Animal Disease Center","ror":"https://ror.org/04ky99h94","country_code":"US","type":"facility","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210142913","https://openalex.org/I4210154632"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Marcus E. Kehrli","raw_affiliation_strings":["Virus and Prion Diseases Research Unit, National Animal Disease Center, USDA-ARS, 1920 Dayton Ave, PO Box 70, Ames, IA 50010, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Virus and Prion Diseases Research Unit, National Animal Disease Center, USDA-ARS, 1920 Dayton Ave, PO Box 70, Ames, IA 50010, USA","institution_ids":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210142913"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5053576640"],"corresponding_institution_ids":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210142913"],"apc_list":{"value":3620,"currency":"USD","value_usd":3620},"apc_paid":null,"fwci":3.4082,"has_fulltext":false,"cited_by_count":75,"citation_normalized_percentile":{"value":0.91799019,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"30","issue":"2","first_page":"280","last_page":"288"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10167","display_name":"Influenza Virus Research Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10167","display_name":"Influenza Virus Research Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11495","display_name":"Animal Virus Infections Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/swine-influenza-virus","display_name":"swine influenza virus","score":0.9909999966621399},{"id":"https://openalex.org/keywords/live-attenuated-vaccine","display_name":"live attenuated vaccine","score":0.6899999976158142},{"id":"https://openalex.org/keywords/h3n2","display_name":"H3N2","score":0.7490000128746033},{"id":"https://openalex.org/keywords/cross-protection","display_name":"cross-protection","score":0.949999988079071},{"id":"https://openalex.org/keywords/t-cell-priming","display_name":"T cell priming","score":0.9039999842643738},{"id":"https://openalex.org/keywords/intranasal-immunization","display_name":"intranasal immunization","score":0.8050000071525574},{"id":"https://openalex.org/keywords/mucosal-immunization","display_name":"mucosal immunization","score":0.6060000061988831},{"id":"https://openalex.org/keywords/cd4-cd8-t-cells","display_name":"CD4+CD8+ T cells","score":0.8500000238418579},{"id":"https://openalex.org/keywords/gamma-delta-t-cells","display_name":"\u03b3\u03b4 T cells","score":0.8920000195503235},{"id":"https://openalex.org/keywords/interferon-gamma","display_name":"interferon-gamma","score":0.8809999823570251},{"id":"https://openalex.org/keywords/th1-cytokines","display_name":"Th1 cytokines","score":0.8100000023841858},{"id":"https://openalex.org/keywords/pigs","display_name":"pigs","score":0.43299999833106995},{"id":"https://openalex.org/keywords/reverse-genetics","display_name":"reverse genetics","score":0.5350000262260437}],"concepts":[{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.7816240787506104},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6818128228187561},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.6797365546226501},{"id":"https://openalex.org/C2777546802","wikidata":"https://www.wikidata.org/wiki/Q834390","display_name":"Influenza A virus","level":3,"score":0.5588697195053101},{"id":"https://openalex.org/C22070199","wikidata":"https://www.wikidata.org/wiki/Q192995","display_name":"Vaccination","level":2,"score":0.532644510269165},{"id":"https://openalex.org/C2778692840","wikidata":"https://www.wikidata.org/wiki/Q9136673","display_name":"Hemagglutinin (influenza)","level":3,"score":0.5164594650268555},{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.5003244876861572},{"id":"https://openalex.org/C140704245","wikidata":"https://www.wikidata.org/wiki/Q3933202","display_name":"Viral replication","level":3,"score":0.4543610215187073},{"id":"https://openalex.org/C81444415","wikidata":"https://www.wikidata.org/wiki/Q7243535","display_name":"Priming (agriculture)","level":3,"score":0.4431511163711548},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.41617506742477417},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3753538131713867},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.31925588846206665},{"id":"https://openalex.org/C100701293","wikidata":"https://www.wikidata.org/wiki/Q193838","display_name":"Germination","level":2,"score":0.0},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000831","descriptor_name":"Animals, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007252","descriptor_name":"Influenza Vaccines","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D007252","descriptor_name":"Influenza Vaccines","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007252","descriptor_name":"Influenza Vaccines","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D009976","descriptor_name":"Orthomyxoviridae Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D009976","descriptor_name":"Orthomyxoviridae Infections","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D014613","descriptor_name":"Vaccines, Attenuated","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D014613","descriptor_name":"Vaccines, Attenuated","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014613","descriptor_name":"Vaccines, Attenuated","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D017361","descriptor_name":"Viral Nonstructural Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D053118","descriptor_name":"Influenza A Virus, H1N1 Subtype","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D053122","descriptor_name":"Influenza A Virus, H3N2 Subtype","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D053122","descriptor_name":"Influenza A Virus, H3N2 Subtype","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D056738","descriptor_name":"Cross Protection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.vaccine.2011.10.098","doi":"https://doi.org/10.1016/j.vaccine.2011.10.098","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.vaccine.2011.10.098","pdf_url":null,"source":{"id":"https://openalex.org/S27359860","display_name":"Vaccine","issn_l":"0264-410X","issn":["0264-410X","1873-2518"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vaccine","raw_type":"journal-article"},{"id":"pmid:22067263","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22067263","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vaccine","raw_type":"Journal Article"},{"id":"pmh:oai:lib.dr.iastate.edu:vmpm_pubs-1076","doi":null,"is_oa":false,"landing_page_url":"https://lib.dr.iastate.edu/vmpm_pubs/83","pdf_url":null,"source":{"id":"https://openalex.org/S4377196104","display_name":"Iowa State University Digital Repository (Iowa State University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I173911158","host_organization_name":"Iowa State University","host_organization_lineage":["https://openalex.org/I173911158"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Veterinary Microbiology and Preventive Medicine Publications","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306114","display_name":"U.S. Department of Agriculture","ror":"https://ror.org/01na82s61"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":40,"referenced_works":["https://openalex.org/W103239798","https://openalex.org/W1967280262","https://openalex.org/W1981480494","https://openalex.org/W1982522376","https://openalex.org/W1989938774","https://openalex.org/W1991159506","https://openalex.org/W2002041201","https://openalex.org/W2002649551","https://openalex.org/W2002727536","https://openalex.org/W2007304389","https://openalex.org/W2008611427","https://openalex.org/W2020464845","https://openalex.org/W2036287577","https://openalex.org/W2040157910","https://openalex.org/W2043175663","https://openalex.org/W2048340513","https://openalex.org/W2050531099","https://openalex.org/W2065193241","https://openalex.org/W2071322149","https://openalex.org/W2071675636","https://openalex.org/W2073625279","https://openalex.org/W2084444709","https://openalex.org/W2109111327","https://openalex.org/W2123298285","https://openalex.org/W2125743639","https://openalex.org/W2126187597","https://openalex.org/W2128940814","https://openalex.org/W2140296277","https://openalex.org/W2143129305","https://openalex.org/W2144633571","https://openalex.org/W2147714365","https://openalex.org/W2148447408","https://openalex.org/W2153203193","https://openalex.org/W2155366460","https://openalex.org/W2163094991","https://openalex.org/W2164655171","https://openalex.org/W2169279776","https://openalex.org/W2256756668","https://openalex.org/W2318325499","https://openalex.org/W6678926214"],"related_works":["https://openalex.org/W2084444709","https://openalex.org/W2008611427","https://openalex.org/W4220824487","https://openalex.org/W2140072049","https://openalex.org/W1520182410","https://openalex.org/W2036000228","https://openalex.org/W2249262875","https://openalex.org/W2127832794","https://openalex.org/W2156541837","https://openalex.org/W1596785013"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}