{"id":"https://openalex.org/W2015563929","doi":"https://doi.org/10.1117/12.613174","title":"Nerve regeneration after femtosecond laser nanosurgery","display_name":"Nerve regeneration after femtosecond laser nanosurgery","publication_year":2005,"publication_date":"2005-03-21","ids":{"openalex":"https://openalex.org/W2015563929","doi":"https://doi.org/10.1117/12.613174","mag":"2015563929"},"language":"en","primary_location":{"id":"doi:10.1117/12.613174","doi":"https://doi.org/10.1117/12.613174","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.613174","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},"volume":null,"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032212627","display_name":"Mehmet Fatih Yanik","orcid":"https://orcid.org/0000-0002-8963-2893","observed_orcids":["https://orcid.org/0000-0002-8963-2893"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mehmet F. Yanik","raw_affiliation_strings":["Stanford Univ. (United States)","Stanford University (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford Univ. (United States)","institution_ids":["https://openalex.org/I97018004"]},{"raw_affiliation_string":"Stanford University (United States)","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022068865","display_name":"Hulusi Cinar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185103710","display_name":"University of California, Santa Cruz","ror":"https://ror.org/03s65by71","country_code":"US","type":"education","lineage":["https://openalex.org/I185103710"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hulusi Cinar","raw_affiliation_strings":["Univ. of California/Santa Cruz (United States)","University of California, Santa Cruz (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. of California/Santa Cruz (United States)","institution_ids":["https://openalex.org/I185103710"]},{"raw_affiliation_string":"University of California, Santa Cruz (United States)","institution_ids":["https://openalex.org/I185103710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038838884","display_name":"Hediye Nese Cinar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185103710","display_name":"University of California, Santa Cruz","ror":"https://ror.org/03s65by71","country_code":"US","type":"education","lineage":["https://openalex.org/I185103710"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hediye N. Cinar","raw_affiliation_strings":["Univ. of California/Santa Cruz (United States)","University of California, Santa Cruz (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. of California/Santa Cruz (United States)","institution_ids":["https://openalex.org/I185103710"]},{"raw_affiliation_string":"University of California, Santa Cruz (United States)","institution_ids":["https://openalex.org/I185103710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041470900","display_name":"Andrew\u00a0D. Chisholm","orcid":"https://orcid.org/0000-0001-5091-0537","observed_orcids":["https://orcid.org/0000-0001-5091-0537"]},"institutions":[{"id":"https://openalex.org/I185103710","display_name":"University of California, Santa Cruz","ror":"https://ror.org/03s65by71","country_code":"US","type":"education","lineage":["https://openalex.org/I185103710"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew D. Chisholm","raw_affiliation_strings":["Univ. of California/Santa Cruz (United States)","University of California, Santa Cruz (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. of California/Santa Cruz (United States)","institution_ids":["https://openalex.org/I185103710"]},{"raw_affiliation_string":"University of California, Santa Cruz (United States)","institution_ids":["https://openalex.org/I185103710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048085131","display_name":"Yishi Jin","orcid":"https://orcid.org/0000-0002-9371-9860","observed_orcids":["https://orcid.org/0000-0002-9371-9860"]},"institutions":[{"id":"https://openalex.org/I185103710","display_name":"University of California, Santa Cruz","ror":"https://ror.org/03s65by71","country_code":"US","type":"education","lineage":["https://openalex.org/I185103710"]},{"id":"https://openalex.org/I86519309","display_name":"The University of Texas at Austin","ror":"https://ror.org/00hj54h04","country_code":"US","type":"education","lineage":["https://openalex.org/I86519309"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yishi Jin","raw_affiliation_strings":["Univ. of California/Santa Cruz (United States)","Univ. of Texas at Austin (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. of California/Santa Cruz (United States)","institution_ids":["https://openalex.org/I185103710"]},{"raw_affiliation_string":"Univ. of Texas at Austin (United States)","institution_ids":["https://openalex.org/I86519309"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002754861","display_name":"Adela Ben\u2010Yakar","orcid":"https://orcid.org/0000-0003-3468-6146","observed_orcids":["https://orcid.org/0000-0003-3468-6146"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Adela Ben-Yakar","raw_affiliation_strings":["Stanford Univ. (United States)","Stanford University (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford Univ. (United States)","institution_ids":["https://openalex.org/I97018004"]},{"raw_affiliation_string":"Stanford University (United States)","institution_ids":["https://openalex.org/I97018004"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.15429494,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"5714","issue":null,"first_page":"138","last_page":"138"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10732","display_name":"Laser Material Processing Techniques","score":0.6615999937057495,"subfield":{"id":"https://openalex.org/subfields/2206","display_name":"Computational Mechanics"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10732","display_name":"Laser Material Processing Techniques","score":0.6615999937057495,"subfield":{"id":"https://openalex.org/subfields/2206","display_name":"Computational Mechanics"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10483","display_name":"Nerve injury and regeneration","score":0.2619999945163727,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.01119999960064888,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nerve-regeneration","display_name":"nerve regeneration","score":0.8830000162124634},{"id":"https://openalex.org/keywords/axotomy","display_name":"axotomy","score":0.8339999914169312},{"id":"https://openalex.org/keywords/caenorhabditis-elegans","display_name":"Caenorhabditis elegans","score":0.984000027179718},{"id":"https://openalex.org/keywords/drug-screening","display_name":"drug screening","score":0.6340000033378601},{"id":"https://openalex.org/keywords/brain-development","display_name":"brain development","score":0.460999995470047}],"concepts":[{"id":"https://openalex.org/C171056886","wikidata":"https://www.wikidata.org/wiki/Q193119","display_name":"Regeneration (biology)","level":2,"score":0.7665828466415405},{"id":"https://openalex.org/C2779683492","wikidata":"https://www.wikidata.org/wiki/Q792615","display_name":"Axotomy","level":3,"score":0.7525391578674316},{"id":"https://openalex.org/C167735695","wikidata":"https://www.wikidata.org/wiki/Q1777507","display_name":"Femtosecond","level":3,"score":0.643007755279541},{"id":"https://openalex.org/C137858568","wikidata":"https://www.wikidata.org/wiki/Q7239","display_name":"Organism","level":2,"score":0.5714880228042603},{"id":"https://openalex.org/C520434653","wikidata":"https://www.wikidata.org/wiki/Q38867","display_name":"Laser","level":2,"score":0.46218690276145935},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4130863547325134},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.32873228192329407},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.32160085439682007},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.23760220408439636},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.20714658498764038},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.1695042848587036},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.16225787997245789},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1117/12.613174","doi":"https://doi.org/10.1117/12.613174","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.613174","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2025619067","https://openalex.org/W2023381874","https://openalex.org/W2133071606","https://openalex.org/W2051249111","https://openalex.org/W2132162535","https://openalex.org/W2076188357","https://openalex.org/W2945440213","https://openalex.org/W2129891016","https://openalex.org/W7097077114","https://openalex.org/W2518919829"],"abstract_inverted_index":{"We":[0],"demonstrate":[1],"sub-micron":[2,86],"scale":[3,87],"surgery":[4],"with":[5],"femtosecond":[6],"lasers":[7],"in":[8,71,76],"a":[9,73],"tiny":[10,74],"living":[11],"organism.":[12],"By":[13],"just":[14],"cutting":[15],"few":[16],"nano-scale":[17],"nerve":[18,69],"connections":[19],"inside":[20],"the":[21,29,39,42,48,54,66],"nematode":[22],"C.":[23],"elegans,":[24],"we":[25],"succeeded":[26],"to":[27,83],"stop":[28],"whole":[30],"animal":[31],"from":[32],"moving":[33],"backwards.":[34],"This":[35],"delicate":[36],"axotomy":[37,88],"keeps":[38],"surrounding":[40],"of":[41,99,103],"severed":[43],"axons":[44,49],"un-damaged":[45],"so":[46],"that":[47],"can":[50,58],"regrow":[51],"back,":[52],"and":[53,57,101,108],"worms":[55],"recover":[56],"move":[59],"backwards":[60],"again.":[61],"These":[62],"results":[63],"demonstrate,":[64],"for":[65,96],"first":[67],"time,":[68],"regeneration":[70,107],"such":[72,90],"organism,":[75],"its":[77],"evolutionarily":[78],"simplest":[79],"form.":[80],"The":[81],"ability":[82],"perform":[84],"precise":[85],"on":[89],"organisms":[91],"provides":[92],"tremendous":[93],"research":[94],"potential":[95],"rapid":[97],"screening":[98],"drugs":[100],"discovery":[102],"new":[104],"biomolecules":[105],"affecting":[106],"development.":[109]},"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2016-06-24T00:00:00"}