{"id":"https://openalex.org/W2015510123","doi":"https://doi.org/10.1016/0006-8993(94)90378-6","title":"Mechanisms of hyperpolarization induced by two cytokines, hTNF\u03b1 and hIL-1\u03b1 in neurons of the mollusc,Onchidium","display_name":"Mechanisms of hyperpolarization induced by two cytokines, hTNF\u03b1 and hIL-1\u03b1 in neurons of the mollusc,Onchidium","publication_year":1994,"publication_date":"1994-08-01","ids":{"openalex":"https://openalex.org/W2015510123","doi":"https://doi.org/10.1016/0006-8993(94)90378-6","mag":"2015510123","pmid":"https://pubmed.ncbi.nlm.nih.gov/7982043"},"language":"en","primary_location":{"id":"doi:10.1016/0006-8993(94)90378-6","doi":"https://doi.org/10.1016/0006-8993(94)90378-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0006-8993(94)90378-6","pdf_url":null,"source":{"id":"https://openalex.org/S96638545","display_name":"Brain Research","issn_l":"0006-8993","issn":["0006-8993","1872-6240"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110035240","display_name":"Yoshihiro Mimura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107139324","display_name":"Kagoshima University","ror":"https://ror.org/03ss88z23","country_code":"JP","type":"education","lineage":["https://openalex.org/I107139324"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshihiro Mimura","raw_affiliation_strings":["Third Department of Internal Medicine, School of Medicine, Kagoshima University, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Third Department of Internal Medicine, School of Medicine, Kagoshima University, Japan","institution_ids":["https://openalex.org/I107139324"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063484343","display_name":"Tsukasa Gotow","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107139324","display_name":"Kagoshima University","ror":"https://ror.org/03ss88z23","country_code":"JP","type":"education","lineage":["https://openalex.org/I107139324"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Tsukasa Gotow","raw_affiliation_strings":["Department of Physiology, School of Medicine, Kagoshima University, Kagoshima 890, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, School of Medicine, Kagoshima University, Kagoshima 890, Japan","institution_ids":["https://openalex.org/I107139324"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070042022","display_name":"Takako Nishi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107139324","display_name":"Kagoshima University","ror":"https://ror.org/03ss88z23","country_code":"JP","type":"education","lineage":["https://openalex.org/I107139324"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takako Nishi","raw_affiliation_strings":["Department of Physiology, School of Medicine, Kagoshima University, Kagoshima 890, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, School of Medicine, Kagoshima University, Kagoshima 890, Japan","institution_ids":["https://openalex.org/I107139324"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110191950","display_name":"Mituhiro Osame","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107139324","display_name":"Kagoshima University","ror":"https://ror.org/03ss88z23","country_code":"JP","type":"education","lineage":["https://openalex.org/I107139324"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Mituhiro Osame","raw_affiliation_strings":["Third Department of Internal Medicine, School of Medicine, Kagoshima University, Kagoshima 890, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Third Department of Internal Medicine, School of Medicine, Kagoshima University, Kagoshima 890, Japan","institution_ids":["https://openalex.org/I107139324"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5063484343"],"corresponding_institution_ids":["https://openalex.org/I107139324"],"apc_list":{"value":3360,"currency":"USD","value_usd":3360},"apc_paid":null,"fwci":0.1062,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.31136002,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"653","issue":"1-2","first_page":"112","last_page":"118"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10493","display_name":"Ion channel regulation and function","score":0.8715999722480774,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10493","display_name":"Ion channel regulation and function","score":0.8715999722480774,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.05730000138282776,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.0066999997943639755,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.906000018119812},{"id":"https://openalex.org/keywords/interleukin-1-alpha","display_name":"interleukin-1 alpha","score":0.9980000257492065},{"id":"https://openalex.org/keywords/hyperpolarization","display_name":"hyperpolarization","score":0.8999999761581421},{"id":"https://openalex.org/keywords/molluscan-neurons","display_name":"molluscan neurons","score":0.6349999904632568},{"id":"https://openalex.org/keywords/onchidium","display_name":"Onchidium","score":0.9850000143051147},{"id":"https://openalex.org/keywords/na-k-atpase","display_name":"Na+/K+-ATPase","score":0.7559999823570251},{"id":"https://openalex.org/keywords/outward-current","display_name":"outward current","score":0.7250000238418579},{"id":"https://openalex.org/keywords/reversal-potential","display_name":"reversal potential","score":0.6669999957084656},{"id":"https://openalex.org/keywords/ganglia","display_name":"ganglia","score":0.3919999897480011}],"concepts":[{"id":"https://openalex.org/C131453863","wikidata":"https://www.wikidata.org/wiki/Q1641079","display_name":"Hyperpolarization (physics)","level":3,"score":0.8638745546340942},{"id":"https://openalex.org/C2779133857","wikidata":"https://www.wikidata.org/wiki/Q285911","display_name":"Ouabain","level":3,"score":0.7040438652038574},{"id":"https://openalex.org/C181911157","wikidata":"https://www.wikidata.org/wiki/Q389844","display_name":"Membrane potential","level":2,"score":0.6499770879745483},{"id":"https://openalex.org/C2778071365","wikidata":"https://www.wikidata.org/wiki/Q3089249","display_name":"Reversal potential","level":4,"score":0.6162903308868408},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5581089854240417},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.534991443157196},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.512022078037262},{"id":"https://openalex.org/C17077164","wikidata":"https://www.wikidata.org/wiki/Q1185869","display_name":"Inhibitory postsynaptic potential","level":2,"score":0.4795122444629669},{"id":"https://openalex.org/C28406088","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Extracellular","level":2,"score":0.477205365896225},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.470889151096344},{"id":"https://openalex.org/C4141045","wikidata":"https://www.wikidata.org/wiki/Q83183","display_name":"Depolarization","level":2,"score":0.46904096007347107},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2648746371269226},{"id":"https://openalex.org/C185263204","wikidata":"https://www.wikidata.org/wiki/Q1154774","display_name":"Electrophysiology","level":2,"score":0.20779293775558472},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.18714213371276855},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1769086718559265},{"id":"https://openalex.org/C147944092","wikidata":"https://www.wikidata.org/wiki/Q176366","display_name":"Patch clamp","level":3,"score":0.17302697896957397},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.10636153817176819},{"id":"https://openalex.org/C537181965","wikidata":"https://www.wikidata.org/wiki/Q658","display_name":"Sodium","level":2,"score":0.08564844727516174},{"id":"https://openalex.org/C66974803","wikidata":"https://www.wikidata.org/wiki/Q10359898","display_name":"Nuclear magnetic resonance spectroscopy","level":2,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000254","descriptor_name":"Sodium-Potassium-Exchanging ATPase","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004594","descriptor_name":"Electrophysiology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007375","descriptor_name":"Interleukin-1","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D007477","descriptor_name":"Ions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008974","descriptor_name":"Mollusca","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D010042","descriptor_name":"Ouabain","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/0006-8993(94)90378-6","doi":"https://doi.org/10.1016/0006-8993(94)90378-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0006-8993(94)90378-6","pdf_url":null,"source":{"id":"https://openalex.org/S96638545","display_name":"Brain Research","issn_l":"0006-8993","issn":["0006-8993","1872-6240"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain Research","raw_type":"journal-article"},{"id":"pmid:7982043","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7982043","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.7742000222206116,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W1848552725","https://openalex.org/W1975580000","https://openalex.org/W1975835564","https://openalex.org/W1996379401","https://openalex.org/W2006469594","https://openalex.org/W2010014711","https://openalex.org/W2010149727","https://openalex.org/W2012359641","https://openalex.org/W2016576655","https://openalex.org/W2022043716","https://openalex.org/W2037863428","https://openalex.org/W2040179836","https://openalex.org/W2041115348","https://openalex.org/W2047183254","https://openalex.org/W2051710261","https://openalex.org/W2054910494","https://openalex.org/W2064768347","https://openalex.org/W2072486140","https://openalex.org/W2084719890","https://openalex.org/W2089172549","https://openalex.org/W2113155773","https://openalex.org/W2113556355","https://openalex.org/W2158264015","https://openalex.org/W2158616380","https://openalex.org/W2159746265","https://openalex.org/W2164180269","https://openalex.org/W2172413152","https://openalex.org/W2182255953","https://openalex.org/W2284112855","https://openalex.org/W2415679589","https://openalex.org/W4238714531","https://openalex.org/W6644228225","https://openalex.org/W6653008245","https://openalex.org/W6664003490","https://openalex.org/W6695646106"],"related_works":["https://openalex.org/W2006469594","https://openalex.org/W2041115348","https://openalex.org/W2399404163","https://openalex.org/W2318182527","https://openalex.org/W2087633012","https://openalex.org/W2022005689","https://openalex.org/W2012359641","https://openalex.org/W2039568691","https://openalex.org/W1999445928","https://openalex.org/W2076763519"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}