{"id":"https://openalex.org/W2015406490","doi":"https://doi.org/10.1159/000242434","title":"Wirksamkeit einer klassisch-hom\u00f6opathischen Therapie bei atopischem Ekzem","display_name":"Wirksamkeit einer klassisch-hom\u00f6opathischen Therapie bei atopischem Ekzem","publication_year":2009,"publication_date":"2009-01-01","ids":{"openalex":"https://openalex.org/W2015406490","doi":"https://doi.org/10.1159/000242434","mag":"2015406490","pmid":"https://pubmed.ncbi.nlm.nih.gov/19887810"},"language":"de","primary_location":{"id":"doi:10.1159/000242434","doi":"https://doi.org/10.1159/000242434","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000242434","pdf_url":null,"source":{"id":"https://openalex.org/S4210208711","display_name":"Forschende Komplement\u00e4rmedizin / Research in Complementary Medicine","issn_l":"1021-7096","issn":["1021-7096","1661-4119","1661-4127"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","poland-40"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Forschende Komplement\u00e4rmedizin / Research in Complementary Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089047742","display_name":"Joachim Siebenwirth","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Joachim Siebenwirth","raw_affiliation_strings":["Private Praxis, Wolfratshausen, Deutschland","Private Praxis, Wolfratshausen,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Private Praxis, Wolfratshausen, Deutschland","institution_ids":[]},{"raw_affiliation_string":"Private Praxis, Wolfratshausen,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068070239","display_name":"Rainer L\u00fcdtke","orcid":"https://orcid.org/0000-0002-7717-1540","observed_orcids":["https://orcid.org/0000-0002-7717-1540"]},"institutions":[{"id":"https://openalex.org/I4210097803","display_name":"Karl und Veronica Carstens-Stiftung","ror":"https://ror.org/00w6s5b11","country_code":"DE","type":"nonprofit","lineage":["https://openalex.org/I4210097803"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Rainer L\u00fcdtke","raw_affiliation_strings":["Karl und Veronica Carstens-Stiftung, Essen,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Karl und Veronica Carstens-Stiftung, Essen,","institution_ids":["https://openalex.org/I4210097803"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109180789","display_name":"Wolfgang Remy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Wolfgang Remy","raw_affiliation_strings":["Klinik und Poliklinik f\u00fcr Dermatologie und Allergologie am Biederstein, Technische Universit\u00e4t M\u00fcnchen, Deutschland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Klinik und Poliklinik f\u00fcr Dermatologie und Allergologie am Biederstein, Technische Universit\u00e4t M\u00fcnchen, Deutschland","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113782844","display_name":"J. Rakoski","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"J\u00fcrgen Rakoski","raw_affiliation_strings":["Klinik und Poliklinik f\u00fcr Dermatologie und Allergologie am Biederstein, Technische Universit\u00e4t M\u00fcnchen, Deutschland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Klinik und Poliklinik f\u00fcr Dermatologie und Allergologie am Biederstein, Technische Universit\u00e4t M\u00fcnchen, Deutschland","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110484768","display_name":"Siegfried Borelli","orcid":"https://orcid.org/0009-0003-9863-6372","observed_orcids":["https://orcid.org/0009-0003-9863-6372"]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Siegfried Borelli","raw_affiliation_strings":["Klinik und Poliklinik f\u00fcr Dermatologie und Allergologie am Biederstein, Technische Universit\u00e4t M\u00fcnchen, Deutschland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Klinik und Poliklinik f\u00fcr Dermatologie und Allergologie am Biederstein, Technische Universit\u00e4t M\u00fcnchen, Deutschland","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102796185","display_name":"Johannes Ring","orcid":"https://orcid.org/0000-0002-9525-0146","observed_orcids":["https://orcid.org/0000-0002-9525-0146"]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Johannes Ring","raw_affiliation_strings":["Klinik und Poliklinik f\u00fcr Dermatologie und Allergologie am Biederstein, Technische Universit\u00e4t M\u00fcnchen, Deutschland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Klinik und Poliklinik f\u00fcr Dermatologie und Allergologie am Biederstein, Technische Universit\u00e4t M\u00fcnchen, Deutschland","institution_ids":["https://openalex.org/I62916508"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":6.5139,"has_fulltext":false,"cited_by_count":29,"citation_normalized_percentile":{"value":0.94984486,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"16","issue":"5","first_page":"315","last_page":"323"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10902","display_name":"Complementary and Alternative Medicine Studies","score":0.95169997215271,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10902","display_name":"Complementary and Alternative Medicine Studies","score":0.95169997215271,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10837","display_name":"Dermatology and Skin Diseases","score":0.046300001442432404,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11033","display_name":"Contact Dermatitis and Allergies","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/atopic-dermatitis","display_name":"atopic dermatitis","score":0.9869999885559082},{"id":"https://openalex.org/keywords/classical-homeopathy","display_name":"classical homeopathy","score":0.9300000071525574},{"id":"https://openalex.org/keywords/homeopathic-remedies","display_name":"homeopathic remedies","score":0.9509999752044678},{"id":"https://openalex.org/keywords/placebo-controlled-comparison","display_name":"placebo comparison","score":0.7889999747276306},{"id":"https://openalex.org/keywords/disease-severity","display_name":"disease severity","score":0.6840000152587891},{"id":"https://openalex.org/keywords/young-adults","display_name":"young adults","score":0.8999999761581421},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.6790000200271606},{"id":"https://openalex.org/keywords/coping","display_name":"coping","score":0.39500001072883606}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8347703814506531},{"id":"https://openalex.org/C176762198","wikidata":"https://www.wikidata.org/wiki/Q81058","display_name":"Homeopathy","level":3,"score":0.786658525466919},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.7381531000137329},{"id":"https://openalex.org/C2778329239","wikidata":"https://www.wikidata.org/wiki/Q268667","display_name":"Atopic dermatitis","level":2,"score":0.7226135730743408},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5267229080200195},{"id":"https://openalex.org/C2780501606","wikidata":"https://www.wikidata.org/wiki/Q7389221","display_name":"SCORAD","level":4,"score":0.5126280188560486},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.46882364153862},{"id":"https://openalex.org/C3017583242","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Placebo group","level":4,"score":0.41995295882225037},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.4184049367904663},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.3856152594089508},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.2648462653160095},{"id":"https://openalex.org/C2776173921","wikidata":"https://www.wikidata.org/wiki/Q25326609","display_name":"Dermatology Life Quality Index","level":3,"score":0.21589124202728271},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.17101144790649414},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.12594452500343323},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003876","descriptor_name":"Dermatitis, Atopic","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D003879","descriptor_name":"Dermatologic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008419","descriptor_name":"Materia Medica","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1159/000242434","doi":"https://doi.org/10.1159/000242434","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000242434","pdf_url":null,"source":{"id":"https://openalex.org/S4210208711","display_name":"Forschende Komplement\u00e4rmedizin / Research in Complementary Medicine","issn_l":"1021-7096","issn":["1021-7096","1661-4119","1661-4127"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","poland-40"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Forschende Komplement\u00e4rmedizin / Research in Complementary Medicine","raw_type":"journal-article"},{"id":"pmid:19887810","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19887810","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Forschende Komplementarmedizin (2006)","raw_type":"English Abstract"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9907000064849854}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.7599999904632568}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W107825694","https://openalex.org/W1495097957","https://openalex.org/W1963571963","https://openalex.org/W1988708288","https://openalex.org/W2002390774","https://openalex.org/W2007879887","https://openalex.org/W2020248538","https://openalex.org/W2032077783","https://openalex.org/W2047838213","https://openalex.org/W2053030907","https://openalex.org/W2055123469","https://openalex.org/W2056618413","https://openalex.org/W2104055403","https://openalex.org/W2110707035","https://openalex.org/W2143138262","https://openalex.org/W2157521962","https://openalex.org/W2317806324","https://openalex.org/W2334129939","https://openalex.org/W2397653884","https://openalex.org/W2407795155","https://openalex.org/W2408642843","https://openalex.org/W2417722524","https://openalex.org/W2485234077","https://openalex.org/W2593244680","https://openalex.org/W3005719673","https://openalex.org/W3134986606"],"related_works":["https://openalex.org/W3153327623","https://openalex.org/W4323350250","https://openalex.org/W2002691880","https://openalex.org/W7212380367","https://openalex.org/W4416613837","https://openalex.org/W7134913759","https://openalex.org/W2053266953","https://openalex.org/W7214501565","https://openalex.org/W7134264151","https://openalex.org/W4410163921"],"abstract_inverted_index":{"BACKGROUND:":[0],"Atopic":[1],"dermatitis":[2,100],"(atopic":[3],"eczema)":[4],"is":[5,253],"one":[6],"of":[7,55,63,109,147,196,200,214,219,251,260,266],"those":[8],"diseases":[9],"where":[10],"homeopaths":[11],"claim":[12],"to":[13,52,169,182,204,241,244,256],"have":[14],"good":[15],"success":[16],"although":[17],"this":[18,233],"has":[19],"never":[20],"been":[21],"proven":[22],"by":[23,94],"rigorously":[24],"controlled":[25],"trials.":[26],"METHODS:":[27],"Single-centre,":[28],"randomised,":[29],"double-blind":[30],"clinical":[31],"trial":[32],"comparing":[33],"homeopathic":[34,236],"remedies":[35,47,237],"with":[36,43,82],"placebo":[37,188,201,245],"in":[38,124,133,173,186,191,198,246],"young":[39],"adults":[40],"(age":[41],"18-35)":[42],"atopic":[44,99,247],"dermatitis.":[45,248],"Homeopathic":[46],"were":[48,68,106,116,122,130],"individually":[49],"administered":[50],"according":[51],"the":[53,76,148,152,174,187,257,263],"rules":[54],"classical":[56],"homeopathy.":[57],"After":[58],"an":[59],"untreated":[60],"baseline":[61,126],"period":[62],"4":[64],"weeks,":[65],"all":[66],"patients":[67,105,135,141,261],"treated":[69],"and":[70,96,118,158,177,262],"monitored":[71],"for":[72],"32":[73],"weeks.":[74],"Throughout":[75],"study,":[77,149,234],"co-medication":[78,159],"was":[79,89,154,160],"allowed":[80],"only":[81],"indifferent":[83],"emollients.":[84],"The":[85,162],"main":[86],"outcome":[87],"parameter":[88,212],"disease":[90],"severity":[91],"as":[92,156],"assessed":[93],"Costa":[95],"Saurat's":[97],"multi-parameter":[98],"score":[101],"(MP-score).":[102],"RESULTS:":[103],"744":[104],"screened":[107],"out":[108,146],"which":[110],"24":[111],"(10":[112],"verum,":[113],"14":[114],"placebo)":[115],"randomised":[117],"analysed.":[119],"Treatment":[120],"groups":[121,226],"balanced":[123],"most":[125],"parameters":[127],"but":[128],"MP-scores":[129],"significantly":[131],"higher":[132],"verum":[134,175],"(p":[136],"=":[137,207],"0.034,":[138],"t-test).":[139],"10":[140],"(5":[142],"per":[143],"group)":[144],"dropped":[145],"mainly":[150],"because":[151],"treatment":[153,220],"perceived":[155],"ineffective":[157],"needed.":[161],"MP-score":[163],"decreased":[164],"from":[165,178],"54.5":[166],"+/-":[167,171,180,184],"11.0":[168],"40.7":[170],"12.5":[172],"group":[176,194],"45.9":[179],"7.6":[181],"32.7":[183],"21.8":[185],"group,":[189],"resulting":[190],"a":[192],"non-significant":[193],"difference":[195],"5.6":[197],"favour":[199],"(CI:":[202],"-9.0":[203],"20.2;":[205],"p":[206,228],"0.46;":[208],"ANCOVA).":[209],"No":[210],"secondary":[211],"(quality":[213],"life,":[215],"coping,":[216],"global":[217],"assessments":[218],"success)":[221],"showed":[222],"significant":[223],"differences":[224],"between":[225],"(all":[227],">":[229],"0.15).":[230],"CONCLUSIONS:":[231],"In":[232],"individualised":[235],"did":[238],"not":[239],"prove":[240],"be":[242],"superior":[243],"Yet,":[249],"generalisability":[250],"results":[252],"limited":[254],"due":[255],"small":[258],"number":[259],"high":[264],"percentage":[265],"ineligible":[267],"patients.":[268]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":5},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}