{"id":"https://openalex.org/W2015385404","doi":"https://doi.org/10.1016/j.neuroscience.2013.10.026","title":"Differential S-nitrosylation of proteins in Alzheimer\u2019s disease","display_name":"Differential S-nitrosylation of proteins in Alzheimer\u2019s disease","publication_year":2013,"publication_date":"2013-10-22","ids":{"openalex":"https://openalex.org/W2015385404","doi":"https://doi.org/10.1016/j.neuroscience.2013.10.026","mag":"2015385404","pmid":"https://pubmed.ncbi.nlm.nih.gov/24157928"},"language":"en","primary_location":{"id":"doi:10.1016/j.neuroscience.2013.10.026","doi":"https://doi.org/10.1016/j.neuroscience.2013.10.026","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.neuroscience.2013.10.026","pdf_url":null,"source":{"id":"https://openalex.org/S30122339","display_name":"Neuroscience","issn_l":"0306-4522","issn":["0306-4522","1873-7544"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-d","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002903421","display_name":"Saadia Zahid","orcid":"https://orcid.org/0000-0003-1667-554X","observed_orcids":["https://orcid.org/0000-0003-1667-554X"]},"institutions":[{"id":"https://openalex.org/I193670377","display_name":"University of Karachi","ror":"https://ror.org/05bbbc791","country_code":"PK","type":"education","lineage":["https://openalex.org/I193670377"]},{"id":"https://openalex.org/I4210116730","display_name":"Universit\u00e4tsmedizin G\u00f6ttingen","ror":"https://ror.org/021ft0n22","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210116730"]}],"countries":["DE","PK"],"is_corresponding":false,"raw_author_name":"S. Zahid","raw_affiliation_strings":["Neurochemistry Research Laboratory, Department of Biochemistry, University of Karachi, Karachi 75270, Pakistan; Department of Clinical Chemistry, University Medical Center Goettingen, Robert-Koch-Str. 40, 37075 Goettingen, Germany","Department of Clinical Chemistry, University Medical Center Goettingen, Robert-Koch-Str. 40, 37075 Goettingen, Germany","Neurochemistry Research Laboratory, Department of Biochemistry, University of Karachi, Karachi 75270, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurochemistry Research Laboratory, Department of Biochemistry, University of Karachi, Karachi 75270, Pakistan; Department of Clinical Chemistry, University Medical Center Goettingen, Robert-Koch-Str. 40, 37075 Goettingen, Germany","institution_ids":["https://openalex.org/I193670377","https://openalex.org/I4210116730"]},{"raw_affiliation_string":"Department of Clinical Chemistry, University Medical Center Goettingen, Robert-Koch-Str. 40, 37075 Goettingen, Germany","institution_ids":["https://openalex.org/I4210116730"]},{"raw_affiliation_string":"Neurochemistry Research Laboratory, Department of Biochemistry, University of Karachi, Karachi 75270, Pakistan","institution_ids":["https://openalex.org/I193670377"]}]},{"author_position":"middle","author":{"id":null,"display_name":"R. Khan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I193670377","display_name":"University of Karachi","ror":"https://ror.org/05bbbc791","country_code":"PK","type":"education","lineage":["https://openalex.org/I193670377"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"R. Khan","raw_affiliation_strings":["Neurochemistry Research Laboratory, Department of Biochemistry, University of Karachi, Karachi 75270, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurochemistry Research Laboratory, Department of Biochemistry, University of Karachi, Karachi 75270, Pakistan","institution_ids":["https://openalex.org/I193670377"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055085283","display_name":"Michael Oellerich","orcid":"https://orcid.org/0000-0002-9255-2261","observed_orcids":["https://orcid.org/0000-0002-9255-2261"]},"institutions":[{"id":"https://openalex.org/I4210116730","display_name":"Universit\u00e4tsmedizin G\u00f6ttingen","ror":"https://ror.org/021ft0n22","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210116730"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"M. Oellerich","raw_affiliation_strings":["Department of Clinical Chemistry, University Medical Center Goettingen, Robert-Koch-Str. 40, 37075 Goettingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Chemistry, University Medical Center Goettingen, Robert-Koch-Str. 40, 37075 Goettingen, Germany","institution_ids":["https://openalex.org/I4210116730"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022788864","display_name":"Nikhat Ahmed","orcid":"https://orcid.org/0000-0001-6345-6740","observed_orcids":["https://orcid.org/0000-0001-6345-6740"]},"institutions":[{"id":"https://openalex.org/I193670377","display_name":"University of Karachi","ror":"https://ror.org/05bbbc791","country_code":"PK","type":"education","lineage":["https://openalex.org/I193670377"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"N. Ahmed","raw_affiliation_strings":["Neurochemistry Research Laboratory, Department of Biochemistry, University of Karachi, Karachi 75270, Pakistan. Electronic address: nikhat_ahmed14@yahoo.co.uk","Neurochemistry Research Laboratory, Department of Biochemistry, University of Karachi, Karachi 75270, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurochemistry Research Laboratory, Department of Biochemistry, University of Karachi, Karachi 75270, Pakistan. Electronic address: nikhat_ahmed14@yahoo.co.uk","institution_ids":["https://openalex.org/I193670377"]},{"raw_affiliation_string":"Neurochemistry Research Laboratory, Department of Biochemistry, University of Karachi, Karachi 75270, Pakistan","institution_ids":["https://openalex.org/I193670377"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5036614893","display_name":"Abdul Rahman Asif","orcid":"https://orcid.org/0000-0002-8581-3187","observed_orcids":["https://orcid.org/0000-0002-8581-3187"]},"institutions":[{"id":"https://openalex.org/I4210116730","display_name":"Universit\u00e4tsmedizin G\u00f6ttingen","ror":"https://ror.org/021ft0n22","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210116730"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"A.R. Asif","raw_affiliation_strings":["Department of Clinical Chemistry, University Medical Center Goettingen, Robert-Koch-Str. 40, 37075 Goettingen, Germany. Electronic address: asif@med.uni-goettingen.de","Department of Clinical Chemistry, University Medical Center Goettingen, Robert-Koch-Str. 40, 37075 Goettingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Chemistry, University Medical Center Goettingen, Robert-Koch-Str. 40, 37075 Goettingen, Germany. Electronic address: asif@med.uni-goettingen.de","institution_ids":["https://openalex.org/I4210116730"]},{"raw_affiliation_string":"Department of Clinical Chemistry, University Medical Center Goettingen, Robert-Koch-Str. 40, 37075 Goettingen, Germany","institution_ids":["https://openalex.org/I4210116730"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3500,"currency":"USD","value_usd":3500},"apc_paid":null,"fwci":3.2478,"has_fulltext":false,"cited_by_count":92,"citation_normalized_percentile":{"value":0.92640975,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"256","issue":null,"first_page":"126","last_page":"136"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.8306000232696533,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.8306000232696533,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11884","display_name":"Redox biology and oxidative stress","score":0.1565999984741211,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/s-nitrosylation","display_name":"S-nitrosylation","score":0.9350000023841858},{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.9520000219345093},{"id":"https://openalex.org/keywords/s-nitrosothiols","display_name":"S-nitrosothiols","score":0.9039999842643738},{"id":"https://openalex.org/keywords/s-nitrosocysteine","display_name":"S-nitrosocysteine","score":0.7910000085830688},{"id":"https://openalex.org/keywords/hippocampus","display_name":"hippocampus","score":0.7720000147819519},{"id":"https://openalex.org/keywords/substantia-nigra","display_name":"substantia nigra","score":1.0},{"id":"https://openalex.org/keywords/cerebral-cortex","display_name":"cerebral cortex","score":0.8619999885559082},{"id":"https://openalex.org/keywords/manganese-superoxide-dismutase","display_name":"manganese superoxide dismutase","score":0.9210000038146973},{"id":"https://openalex.org/keywords/vdac2","display_name":"VDAC2","score":0.9210000038146973},{"id":"https://openalex.org/keywords/neuronal-atrophy","display_name":"neuronal atrophy","score":0.8849999904632568},{"id":"https://openalex.org/keywords/protein-misfolding","display_name":"protein misfolding","score":0.5799999833106995},{"id":"https://openalex.org/keywords/redox-regulation","display_name":"redox regulation","score":0.6359999775886536},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.5360000133514404}],"concepts":[{"id":"https://openalex.org/C2777553025","wikidata":"https://www.wikidata.org/wiki/Q25323683","display_name":"S-Nitrosylation","level":4,"score":0.8177518844604492},{"id":"https://openalex.org/C502032728","wikidata":"https://www.wikidata.org/wiki/Q11081","display_name":"Alzheimer's disease","level":3,"score":0.5818713903427124},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5554990172386169},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4983515739440918},{"id":"https://openalex.org/C93226319","wikidata":"https://www.wikidata.org/wiki/Q193137","display_name":"Differential (mechanical device)","level":2,"score":0.4364357888698578},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3633735179901123},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.258301317691803},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.12747761607170105},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09183299541473389},{"id":"https://openalex.org/C2779201268","wikidata":"https://www.wikidata.org/wiki/Q186474","display_name":"Cysteine","level":3,"score":0.07672342658042908},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.05360838770866394},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000099156","descriptor_name":"Superoxide Dismutase 2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001710","descriptor_name":"Biotin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D003545","descriptor_name":"Cysteine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005634","descriptor_name":"Fructose-Bisphosphate Aldolase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013482","descriptor_name":"Superoxide Dismutase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015180","descriptor_name":"Electrophoresis, Gel, Two-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D026403","descriptor_name":"S-Nitrosothiols","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050996","descriptor_name":"Voltage-Dependent Anion Channel 2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D053719","descriptor_name":"Tandem Mass Spectrometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.neuroscience.2013.10.026","doi":"https://doi.org/10.1016/j.neuroscience.2013.10.026","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.neuroscience.2013.10.026","pdf_url":null,"source":{"id":"https://openalex.org/S30122339","display_name":"Neuroscience","issn_l":"0306-4522","issn":["0306-4522","1873-7544"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-d","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience","raw_type":"journal-article"},{"id":"pmid:24157928","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24157928","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience","raw_type":"Journal Article"},{"id":"pmh:oai:publications.goettingen-research-online.de:2/34570","doi":null,"is_oa":false,"landing_page_url":"https://resolver.sub.uni-goettingen.de/purl?gro-2/34570","pdf_url":null,"source":{"id":"https://openalex.org/S7407055187","display_name":"GRO","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":49,"referenced_works":["https://openalex.org/W1505503094","https://openalex.org/W1507608406","https://openalex.org/W1534880720","https://openalex.org/W1590831151","https://openalex.org/W1965891907","https://openalex.org/W1970308606","https://openalex.org/W1973864912","https://openalex.org/W1979927187","https://openalex.org/W1980548655","https://openalex.org/W1981558989","https://openalex.org/W1993849593","https://openalex.org/W1994461623","https://openalex.org/W1994771592","https://openalex.org/W2002979560","https://openalex.org/W2003946735","https://openalex.org/W2005086972","https://openalex.org/W2005845714","https://openalex.org/W2009202347","https://openalex.org/W2010056243","https://openalex.org/W2012870439","https://openalex.org/W2029874231","https://openalex.org/W2031065747","https://openalex.org/W2044853699","https://openalex.org/W2047832965","https://openalex.org/W2049378335","https://openalex.org/W2051876980","https://openalex.org/W2053796870","https://openalex.org/W2054777631","https://openalex.org/W2074595259","https://openalex.org/W2076740879","https://openalex.org/W2078594804","https://openalex.org/W2078825687","https://openalex.org/W2081947989","https://openalex.org/W2093162508","https://openalex.org/W2107259248","https://openalex.org/W2108433881","https://openalex.org/W2113613985","https://openalex.org/W2115816694","https://openalex.org/W2125258716","https://openalex.org/W2135986226","https://openalex.org/W2140807512","https://openalex.org/W2144956444","https://openalex.org/W2148896980","https://openalex.org/W2155893598","https://openalex.org/W2157430977","https://openalex.org/W2160219722","https://openalex.org/W2162629716","https://openalex.org/W2164545630","https://openalex.org/W6630213393"],"related_works":["https://openalex.org/W2088729484","https://openalex.org/W7033556433","https://openalex.org/W2972561249","https://openalex.org/W2140005295","https://openalex.org/W2552848935","https://openalex.org/W2311894028","https://openalex.org/W2524116930","https://openalex.org/W2980281056","https://openalex.org/W2498069090","https://openalex.org/W2066261432"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":10},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":10},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":13},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}