{"id":"https://openalex.org/W2015346606","doi":"https://doi.org/10.3389/fncel.2012.00003","title":"GABA Not Only a Neurotransmitter: Osmotic Regulation by GABAAR Signaling","display_name":"GABA Not Only a Neurotransmitter: Osmotic Regulation by GABAAR Signaling","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W2015346606","doi":"https://doi.org/10.3389/fncel.2012.00003","mag":"2015346606","pmid":"https://pubmed.ncbi.nlm.nih.gov/22319472","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3268181"},"language":"en","primary_location":{"id":"doi:10.3389/fncel.2012.00003","doi":"https://doi.org/10.3389/fncel.2012.00003","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fncel.2012.00003","pdf_url":"https://www.frontiersin.org/articles/10.3389/fncel.2012.00003/pdf","source":{"id":"https://openalex.org/S36653316","display_name":"Frontiers in Cellular Neuroscience","issn_l":"1662-5102","issn":["1662-5102"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Cellular Neuroscience","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fncel.2012.00003/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5105786764","display_name":"Tiziana Cesetti","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I223822909","display_name":"Heidelberg University","ror":"https://ror.org/038t36y30","country_code":"DE","type":"education","lineage":["https://openalex.org/I223822909"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Tiziana Cesetti","raw_affiliation_strings":["Department of Physiology and Pathophysiology, Interdisciplinary Center for Neurosciences, University of Heidelberg Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Pathophysiology, Interdisciplinary Center for Neurosciences, University of Heidelberg Heidelberg, Germany","institution_ids":["https://openalex.org/I223822909"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033958281","display_name":"Francesca Ciccolini","orcid":"https://orcid.org/0000-0002-7276-7361","observed_orcids":["https://orcid.org/0000-0002-7276-7361"]},"institutions":[{"id":"https://openalex.org/I223822909","display_name":"Heidelberg University","ror":"https://ror.org/038t36y30","country_code":"DE","type":"education","lineage":["https://openalex.org/I223822909"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Francesca Ciccolini","raw_affiliation_strings":["University of Heidelberg, IZN neurobiology, Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Heidelberg, IZN neurobiology, Heidelberg, Germany","institution_ids":["https://openalex.org/I223822909"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100377770","display_name":"Yuting Li","orcid":"https://orcid.org/0000-0002-6296-4054","observed_orcids":["https://orcid.org/0000-0002-6296-4054"]},"institutions":[{"id":"https://openalex.org/I223822909","display_name":"Heidelberg University","ror":"https://ror.org/038t36y30","country_code":"DE","type":"education","lineage":["https://openalex.org/I223822909"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Yuting Li","raw_affiliation_strings":["University of Heidelberg, IZN neurobiology, Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Heidelberg, IZN neurobiology, Heidelberg, Germany","institution_ids":["https://openalex.org/I223822909"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5033958281"],"corresponding_institution_ids":["https://openalex.org/I223822909"],"apc_list":{"value":3150,"currency":"CHF","value_usd":3801},"apc_paid":{"value":3150,"currency":"CHF","value_usd":3801},"fwci":0.3072,"has_fulltext":true,"cited_by_count":28,"citation_normalized_percentile":{"value":0.48717526,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"6","issue":null,"first_page":"3","last_page":"3"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.7134000062942505,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.7134000062942505,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.2678000032901764,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11406","display_name":"Cerebrospinal fluid and hydrocephalus","score":0.004900000058114529,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gaba-a-receptor","display_name":"GABAA receptor","score":0.9350000023841858},{"id":"https://openalex.org/keywords/osmoregulation","display_name":"osmoregulation","score":0.8619999885559082},{"id":"https://openalex.org/keywords/brain-water-homeostasis","display_name":"brain water homeostasis","score":0.824999988079071},{"id":"https://openalex.org/keywords/chloride-homeostasis","display_name":"chloride homeostasis","score":0.7429999709129333},{"id":"https://openalex.org/keywords/water-flux","display_name":"water flux","score":0.41499999165534973},{"id":"https://openalex.org/keywords/aquaporins","display_name":"aquaporins","score":0.5550000071525574},{"id":"https://openalex.org/keywords/ion-transport","display_name":"ion transport","score":0.7170000076293945},{"id":"https://openalex.org/keywords/macroglia","display_name":"macroglia","score":0.7889999747276306},{"id":"https://openalex.org/keywords/neural-stem-cells","display_name":"neural stem cells","score":0.9679999947547913},{"id":"https://openalex.org/keywords/cell-volume-regulation","display_name":"cell volume regulation","score":0.6759999990463257},{"id":"https://openalex.org/keywords/gabaergic-transmission","display_name":"GABAergic neurotransmission","score":0.5649999976158142}],"concepts":[{"id":"https://openalex.org/C2776219046","wikidata":"https://www.wikidata.org/wiki/Q162657","display_name":"Neurotransmitter","level":3,"score":0.7384735345840454},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5819862484931946},{"id":"https://openalex.org/C156927020","wikidata":"https://www.wikidata.org/wiki/Q1187783","display_name":"Neurotransmitter receptor","level":3,"score":0.4464492201805115},{"id":"https://openalex.org/C3017459112","wikidata":"https://www.wikidata.org/wiki/Q162657","display_name":"Neurotransmitter systems","level":3,"score":0.43345749378204346},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3220868706703186},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.2886486053466797},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.2413075864315033},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.206301748752594},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09596335887908936},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.08338561654090881}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.3389/fncel.2012.00003","doi":"https://doi.org/10.3389/fncel.2012.00003","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fncel.2012.00003","pdf_url":"https://www.frontiersin.org/articles/10.3389/fncel.2012.00003/pdf","source":{"id":"https://openalex.org/S36653316","display_name":"Frontiers in Cellular Neuroscience","issn_l":"1662-5102","issn":["1662-5102"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Cellular Neuroscience","raw_type":"journal-article"},{"id":"pmid:22319472","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22319472","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in cellular neuroscience","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3268181","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3268181/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Cell Neurosci","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:242f5e9fa1c14111b7f17de695be76b8","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/242f5e9fa1c14111b7f17de695be76b8","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Cellular Neuroscience, Vol 6 (2012)","raw_type":"article"},{"id":"mag:3145088685","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/242f5e9fa1c14111b7f17de695be76b8","pdf_url":null,"source":{"id":"https://openalex.org/S36653316","display_name":"Frontiers in Cellular Neuroscience","issn_l":"1662-5102","issn":["1662-5102"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Cellular Neuroscience","raw_type":null}],"best_oa_location":{"id":"doi:10.3389/fncel.2012.00003","doi":"https://doi.org/10.3389/fncel.2012.00003","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fncel.2012.00003","pdf_url":"https://www.frontiersin.org/articles/10.3389/fncel.2012.00003/pdf","source":{"id":"https://openalex.org/S36653316","display_name":"Frontiers in Cellular Neuroscience","issn_l":"1662-5102","issn":["1662-5102"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Cellular Neuroscience","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2015346606.pdf","grobid_xml":"https://content.openalex.org/works/W2015346606.grobid-xml"},"referenced_works_count":142,"referenced_works":["https://openalex.org/W71117577","https://openalex.org/W1489121151","https://openalex.org/W1556211232","https://openalex.org/W1570517521","https://openalex.org/W1608349175","https://openalex.org/W1631445977","https://openalex.org/W1644182666","https://openalex.org/W1705218924","https://openalex.org/W1730756591","https://openalex.org/W1893559159","https://openalex.org/W1937363507","https://openalex.org/W1941392759","https://openalex.org/W1964221757","https://openalex.org/W1966124318","https://openalex.org/W1968418117","https://openalex.org/W1970610673","https://openalex.org/W1971848028","https://openalex.org/W1974554283","https://openalex.org/W1975239722","https://openalex.org/W1975517087","https://openalex.org/W1976339181","https://openalex.org/W1979717718","https://openalex.org/W1981133890","https://openalex.org/W1983284668","https://openalex.org/W1983546912","https://openalex.org/W1987204817","https://openalex.org/W1987736773","https://openalex.org/W1987834187","https://openalex.org/W1988340492","https://openalex.org/W1988352722","https://openalex.org/W1991046550","https://openalex.org/W1991100489","https://openalex.org/W1991143203","https://openalex.org/W1991166898","https://openalex.org/W1992589532","https://openalex.org/W1993064394","https://openalex.org/W1994293913","https://openalex.org/W1994698746","https://openalex.org/W1995167437","https://openalex.org/W1995793237","https://openalex.org/W1999231295","https://openalex.org/W1999867852","https://openalex.org/W2001972362","https://openalex.org/W2002889756","https://openalex.org/W2004430506","https://openalex.org/W2005416529","https://openalex.org/W2006842487","https://openalex.org/W2007076123","https://openalex.org/W2007654857","https://openalex.org/W2011262315","https://openalex.org/W2013688792","https://openalex.org/W2014362797","https://openalex.org/W2019153537","https://openalex.org/W2019861866","https://openalex.org/W2020487122","https://openalex.org/W2024642025","https://openalex.org/W2027877074","https://openalex.org/W2029729156","https://openalex.org/W2029839239","https://openalex.org/W2031275782","https://openalex.org/W2032081130","https://openalex.org/W2032451394","https://openalex.org/W2035046505","https://openalex.org/W2036067700","https://openalex.org/W2036305842","https://openalex.org/W2037984086","https://openalex.org/W2039299884","https://openalex.org/W2039823758","https://openalex.org/W2042027195","https://openalex.org/W2046611979","https://openalex.org/W2048231004","https://openalex.org/W2048882295","https://openalex.org/W2051143596","https://openalex.org/W2051222535","https://openalex.org/W2052242727","https://openalex.org/W2052465889","https://openalex.org/W2053345445","https://openalex.org/W2053581898","https://openalex.org/W2054475807","https://openalex.org/W2056111826","https://openalex.org/W2056740618","https://openalex.org/W2057761610","https://openalex.org/W2058156281","https://openalex.org/W2058897457","https://openalex.org/W2063400281","https://openalex.org/W2063663360","https://openalex.org/W2064907262","https://openalex.org/W2065031748","https://openalex.org/W2065145174","https://openalex.org/W2065372694","https://openalex.org/W2066301717","https://openalex.org/W2066840018","https://openalex.org/W2067018626","https://openalex.org/W2067330218","https://openalex.org/W2070169336","https://openalex.org/W2071743480","https://openalex.org/W2072003572","https://openalex.org/W2073487012","https://openalex.org/W2073536847","https://openalex.org/W2080466385","https://openalex.org/W2081033826","https://openalex.org/W2083520967","https://openalex.org/W2086517873","https://openalex.org/W2087561238","https://openalex.org/W2087782077","https://openalex.org/W2088228189","https://openalex.org/W2090137827","https://openalex.org/W2090592195","https://openalex.org/W2090845949","https://openalex.org/W2092168013","https://openalex.org/W2094566223","https://openalex.org/W2098237962","https://openalex.org/W2100980725","https://openalex.org/W2101357874","https://openalex.org/W2108469833","https://openalex.org/W2110623540","https://openalex.org/W2113184411","https://openalex.org/W2121009504","https://openalex.org/W2126578880","https://openalex.org/W2128725941","https://openalex.org/W2129410877","https://openalex.org/W2135544759","https://openalex.org/W2136491540","https://openalex.org/W2136755347","https://openalex.org/W2145172383","https://openalex.org/W2145450755","https://openalex.org/W2151201474","https://openalex.org/W2153978690","https://openalex.org/W2156302680","https://openalex.org/W2157017564","https://openalex.org/W2159977558","https://openalex.org/W2161121393","https://openalex.org/W2164236178","https://openalex.org/W2169053935","https://openalex.org/W2171386529","https://openalex.org/W2171404927","https://openalex.org/W2230118829","https://openalex.org/W2338983518","https://openalex.org/W2399612083","https://openalex.org/W2411739679","https://openalex.org/W2460207933","https://openalex.org/W2740629701"],"related_works":["https://openalex.org/W7097933416","https://openalex.org/W3145088685","https://openalex.org/W2028453669","https://openalex.org/W2014362797","https://openalex.org/W2505436522","https://openalex.org/W3006916543","https://openalex.org/W4241291114","https://openalex.org/W202619460","https://openalex.org/W2307708043","https://openalex.org/W2029596063"],"abstract_inverted_index":{"In":[0,91,142],"neurons":[1],"the":[2,17,32,38,106,118,136,159,166,169,178,181,193,220,233,257,262,269,279],"anionic":[3],"channel":[4],"\u03b3-aminobutyric":[5],"(GABA)":[6],"A":[7],"receptor":[8,27],"(GABAAR)":[9],"plays":[10,122],"a":[11,123],"central":[12,39],"role":[13,21,125],"in":[14,37,47,51,65,74,126,135,278],"mediating":[15],"both":[16],"neurotrophic":[18],"and":[19,50,121,153,171,201,212,236,241,267],"neurotransmitter":[20],"of":[22,25,34,62,88,101,161,168,180,239,259,264,271],"GABA.":[23],"Activation":[24],"this":[26],"by":[28,138,164,231],"GABA":[29,63,89],"also":[30,147,163,185,216],"affects":[31],"function":[33,167],"non-neuronal":[35,66,92],"cells":[36,67,84,93],"nervous":[40],"system":[41],"(CNS),":[42],"as":[43,196],"GABAARs":[44],"are":[45,85],"expressed":[46],"mature":[48],"macroglia":[49],"almost":[52],"all":[53],"progenitor":[54],"types,":[55],"including":[56],"neural":[57],"stem":[58],"cells.":[59],"The":[60],"relevance":[61],"signalling":[64,156,205],"has":[68,190],"been":[69],"comparatively":[70],"less":[71],"investigated":[72],"than":[73],"neurons.":[75],"However,":[76],"it":[77,197,225],"is":[78,111],"becoming":[79],"increasingly":[80],"evident":[81],"that":[82],"these":[83],"direct":[86],"targets":[87],"regulation.":[90],"GABAAR":[94,130,155,265],"activation":[95],"leads":[96],"to":[97,114,243],"influx":[98],"or":[99],"efflux":[100],"chloride":[102],"(Cl-)":[103],"depending":[104],"on":[105],"electrochemical":[107],"gradient.":[108],"Ion":[109],"transport":[110],"indissolubly":[112],"associated":[113],"water":[115,145,151,162,182,245,276],"fluxes":[116,183],"across":[117],"plasma":[119],"membrane":[120],"key":[124],"brain":[127,137,244],"physiology.":[128],"Therefore,":[129,247],"could":[131,157],"affect":[132,158],"osmotic":[133,249],"tension":[134],"modulating":[139],"ion":[140],"gradients.":[141],"addition,":[143],"since":[144],"movements":[146],"occur":[148],"through":[149],"specialized":[150],"channels":[152,170],"transporters,":[154],"movement":[160],"regulating":[165,232],"transporters":[172],"involved,":[173],"thereby":[174],"affecting":[175],"not":[176],"only":[177],"direction":[179],"but":[184],"their":[186],"dynamics.":[187],"This":[188],"regulation":[189,250],"consequences":[191,218],"at":[192,219],"cellular":[194],"level":[195],"modulates":[198],"cell":[199,209],"volume":[200],"activates":[202],"multiple":[203],"intracellular":[204],"mechanisms":[206],"important":[207],"for":[208,268,273],"proliferation,":[210],"maturation":[211],"survival.":[213],"It":[214],"may":[215,226],"have":[217],"systemic":[221],"level.":[222],"For":[223],"example,":[224],"indirectly":[227],"control":[228],"neuronal":[229],"excitability,":[230],"extracellular":[234],"space":[235],"interstitial":[237],"concentration":[238],"Cl-,":[240],"contribute":[242],"homeostasis.":[246],"GABAergic":[248],"should":[251],"be":[252],"taken":[253],"into":[254],"account":[255],"during":[256],"treatment":[258],"pathologies":[260],"requiring":[261],"administration":[263],"modulators":[266],"development":[270],"therapies":[272],"diseases":[274],"causing":[275],"unbalance":[277],"brain.":[280]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}
