{"id":"https://openalex.org/W2015310727","doi":"https://doi.org/10.1111/j.1464-410x.1974.tb03827.x","title":"The Incidence, Investigation and Treatment of Idiopathic Hypercalciuria","display_name":"The Incidence, Investigation and Treatment of Idiopathic Hypercalciuria","publication_year":1974,"publication_date":"1974-06-01","ids":{"openalex":"https://openalex.org/W2015310727","doi":"https://doi.org/10.1111/j.1464-410x.1974.tb03827.x","mag":"2015310727","pmid":"https://pubmed.ncbi.nlm.nih.gov/4846153"},"language":"en","primary_location":{"id":"doi:10.1111/j.1464-410x.1974.tb03827.x","doi":"https://doi.org/10.1111/j.1464-410x.1974.tb03827.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1464-410x.1974.tb03827.x","pdf_url":null,"source":{"id":"https://openalex.org/S4210229390","display_name":"British Journal of Urology","issn_l":"0007-1331","issn":["0007-1331","1365-2176"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Urology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113628843","display_name":"G. Alan Rose","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"G. ALAN ROSE","raw_affiliation_strings":["St Peter's Hospitals and Institute of Urology, London"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"St Peter's Hospitals and Institute of Urology, London","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108491928","display_name":"A. R. Harrison","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A. R. HARRISON","raw_affiliation_strings":["St Peter's Hospitals and Institute of Urology, London"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"St Peter's Hospitals and Institute of Urology, London","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5113628843"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":15.0841,"has_fulltext":false,"cited_by_count":56,"citation_normalized_percentile":{"value":0.98987627,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":null,"biblio":{"volume":"46","issue":"3","first_page":"261","last_page":"274"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10606","display_name":"Kidney Stones and Urolithiasis Treatments","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10606","display_name":"Kidney Stones and Urolithiasis Treatments","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11139","display_name":"Gout, Hyperuricemia, Uric Acid","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/idiopathic-hypercalciuria","display_name":"idiopathic hypercalciuria","score":1.0},{"id":"https://openalex.org/keywords/kidney-stones","display_name":"kidney stones","score":0.9300000071525574},{"id":"https://openalex.org/keywords/urinary-calcium","display_name":"urinary calcium","score":0.6990000009536743},{"id":"https://openalex.org/keywords/plasma-calcium","display_name":"plasma calcium","score":0.6620000004768372},{"id":"https://openalex.org/keywords/plasma-inorganic-phosphate","display_name":"plasma inorganic phosphate","score":0.8790000081062317},{"id":"https://openalex.org/keywords/plasma-urate","display_name":"plasma urate","score":0.9150000214576721},{"id":"https://openalex.org/keywords/thiazide-diuretics","display_name":"thiazide diuretics","score":0.9100000262260437},{"id":"https://openalex.org/keywords/bendrofluazide","display_name":"bendrofluazide","score":0.9570000171661377},{"id":"https://openalex.org/keywords/cellulose-phosphate","display_name":"cellulose phosphate","score":0.8539999723434448},{"id":"https://openalex.org/keywords/calcium-binding-agents","display_name":"calcium-binding agents","score":0.5070000290870667},{"id":"https://openalex.org/keywords/stone-prevention","display_name":"stone prevention","score":0.4480000138282776}],"concepts":[{"id":"https://openalex.org/C2777724520","wikidata":"https://www.wikidata.org/wiki/Q2526358","display_name":"Hypercalciuria","level":3,"score":0.9091958999633789},{"id":"https://openalex.org/C2780437262","wikidata":"https://www.wikidata.org/wiki/Q665843","display_name":"Thiazide","level":3,"score":0.6961802244186401},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.6506211757659912},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6372841000556946},{"id":"https://openalex.org/C2776697488","wikidata":"https://www.wikidata.org/wiki/Q4210589","display_name":"Urinary calcium","level":3,"score":0.5906890630722046},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.5720467567443848},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5401896238327026},{"id":"https://openalex.org/C77411442","wikidata":"https://www.wikidata.org/wiki/Q181100","display_name":"Urinary system","level":2,"score":0.5043784379959106},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.49375757575035095},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.48945772647857666},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.486272931098938},{"id":"https://openalex.org/C2777132085","wikidata":"https://www.wikidata.org/wiki/Q46220103","display_name":"Phosphate","level":2,"score":0.47577300667762756},{"id":"https://openalex.org/C2779918671","wikidata":"https://www.wikidata.org/wiki/Q200656","display_name":"Diuretic","level":2,"score":0.347720742225647},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2649640142917633},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09902024269104004},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000367","descriptor_name":"Age Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001539","descriptor_name":"Bendroflumethiazide","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":true},{"descriptor_ui":"D002128","descriptor_name":"Calcium Metabolism Disorders","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D002128","descriptor_name":"Calcium Metabolism Disorders","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D002128","descriptor_name":"Calcium Metabolism Disorders","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":true},{"descriptor_ui":"D002136","descriptor_name":"Calcium, Dietary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002482","descriptor_name":"Cellulose","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007669","descriptor_name":"Kidney Calculi","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D007691","descriptor_name":"Medullary Sponge Kidney","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D008131","descriptor_name":"London","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010710","descriptor_name":"Phosphates","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D014527","descriptor_name":"Uric Acid","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1464-410x.1974.tb03827.x","doi":"https://doi.org/10.1111/j.1464-410x.1974.tb03827.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1464-410x.1974.tb03827.x","pdf_url":null,"source":{"id":"https://openalex.org/S4210229390","display_name":"British Journal of Urology","issn_l":"0007-1331","issn":["0007-1331","1365-2176"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Urology","raw_type":"journal-article"},{"id":"pmid:4846153","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/4846153","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British journal of urology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W19424983","https://openalex.org/W127344135","https://openalex.org/W339925844","https://openalex.org/W1561445821","https://openalex.org/W1749200137","https://openalex.org/W1983659153","https://openalex.org/W2004133224","https://openalex.org/W2015626654","https://openalex.org/W2033978181","https://openalex.org/W2043055225","https://openalex.org/W2064236437","https://openalex.org/W2084151013","https://openalex.org/W2085328146","https://openalex.org/W2128985458","https://openalex.org/W2196980026","https://openalex.org/W2243068197","https://openalex.org/W2272639609","https://openalex.org/W2317174401","https://openalex.org/W2347020192","https://openalex.org/W2397636220","https://openalex.org/W2409088068","https://openalex.org/W2409516032","https://openalex.org/W2412521593","https://openalex.org/W2416769269","https://openalex.org/W2426037049","https://openalex.org/W2431897265","https://openalex.org/W2433147043","https://openalex.org/W2731410681","https://openalex.org/W2982732254","https://openalex.org/W4206305834","https://openalex.org/W4252172859","https://openalex.org/W6845878647"],"related_works":["https://openalex.org/W2231785048","https://openalex.org/W2055353808","https://openalex.org/W2101287440","https://openalex.org/W4301477662","https://openalex.org/W2262905614","https://openalex.org/W2409908341","https://openalex.org/W2048857684","https://openalex.org/W2279655465","https://openalex.org/W2051408651","https://openalex.org/W4250999454"],"abstract_inverted_index":{"Summary":[0],"A":[1,52],"hundred":[2],"and":[3,19,84,131],"eight":[4],"patients":[5,30,56,101],"with":[6,57,66,102,106,138],"renal":[7,47],"calculi":[8,48],"attending":[9],"a":[10,70],"single":[11],"clinic":[12],"were":[13,60],"studied":[14],"in":[15,49,117,133],"order":[16],"to":[17,34,69],"try":[18],"establish":[20],"the":[21,42,97,134],"primary":[22],"cause":[23,45],"of":[24,28,46,54,100],"their":[25],"stones.":[26],"Sixty\u2010six":[27],"these":[29],"(61":[31],"%)":[32],"proved":[33],"have":[35],"idiopathic":[36,58,103],"hypercalciuria,":[37],"confirming":[38],"that":[39],"this":[40],"is":[41],"most":[43],"common":[44],"adult":[50],"males.":[51],"total":[53],"87":[55],"hypercalciuria":[59,104],"investigated.":[61],"Plasma":[62],"calcium":[63,99,120],"was":[64,77,121,146],"normal":[65],"no":[67],"\u201ctendency":[68],"low":[71],"plasma":[72,74,85],"calcium\u201d,":[73],"inorganic":[75],"phosphate":[76,110,129],"only":[78,87],"0\u20135":[79,88],"mg/100":[80,89],"ml":[81,90],"below":[82],"normal,":[83],"urate":[86],"above":[91],"normal.":[92],"The":[93,114,142],"long\u2010term":[94],"effect":[95],"on":[96],"urinary":[98,119],"treated":[105,137],"bendrofluazide":[107],"and/or":[108],"cellulose":[109,128],"has":[111],"been":[112],"studied.":[113],"success":[115,144],"rate":[116,145],"lowering":[118],"54%":[122],"for":[123,127],"thiazide":[124],"alone,":[125,130],"60%":[126],"100%":[132],"small":[135],"number":[136],"both":[139],"drugs":[140],"together.":[141],"overall":[143],"75":[147],"%,":[148],"but":[149],"may":[150],"yet":[151],"rise":[152],"further.":[153]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}