{"id":"https://openalex.org/W2015280506","doi":"https://doi.org/10.1016/0006-2952(78)90390-8","title":"Synovial fluid degradation induced by free radicals. In vitro action of several free radical scavengers and anti-inflammatory drugs","display_name":"Synovial fluid degradation induced by free radicals. In vitro action of several free radical scavengers and anti-inflammatory drugs","publication_year":1978,"publication_date":"1978-02-01","ids":{"openalex":"https://openalex.org/W2015280506","doi":"https://doi.org/10.1016/0006-2952(78)90390-8","mag":"2015280506","pmid":"https://pubmed.ncbi.nlm.nih.gov/629812"},"language":"en","primary_location":{"id":"doi:10.1016/0006-2952(78)90390-8","doi":"https://doi.org/10.1016/0006-2952(78)90390-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0006-2952(78)90390-8","pdf_url":null,"source":{"id":"https://openalex.org/S185534594","display_name":"Biochemical Pharmacology","issn_l":"0006-2952","issn":["0006-2952","1873-2968"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical Pharmacology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111776654","display_name":"P. Puig\u2010Parellada","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"P. Puig-Parellada","raw_affiliation_strings":["Department of Pharmacology, Faculty of Medicine, University of Barcelona, Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, Faculty of Medicine, University of Barcelona, Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109169837","display_name":"J.M. Planas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"J.M. Planas","raw_affiliation_strings":["Department of Pharmacology, Faculty of Medicine, University of Barcelona, Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, Faculty of Medicine, University of Barcelona, Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I71999127"],"apc_list":{"value":3590,"currency":"USD","value_usd":3590},"apc_paid":null,"fwci":4.9214,"has_fulltext":false,"cited_by_count":64,"citation_normalized_percentile":{"value":0.94925373,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":93},"biblio":{"volume":"27","issue":"4","first_page":"535","last_page":"537"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.4115999937057495,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.4115999937057495,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11884","display_name":"Redox biology and oxidative stress","score":0.1354999989271164,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13013","display_name":"Free Radicals and Antioxidants","score":0.13230000436306,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/free-radicals","display_name":"free radicals","score":0.9290000200271606},{"id":"https://openalex.org/keywords/free-radical-scavengers","display_name":"radical scavengers","score":0.8389999866485596},{"id":"https://openalex.org/keywords/anti-inflammatory-agents","display_name":"anti-inflammatory agents","score":0.8880000114440918},{"id":"https://openalex.org/keywords/xanthine-oxidase","display_name":"xanthine oxidase","score":0.8330000042915344},{"id":"https://openalex.org/keywords/hypoxanthine","display_name":"hypoxanthine","score":0.9599999785423279},{"id":"https://openalex.org/keywords/hydroxyl-radicals","display_name":"hydroxyl radicals","score":0.7649999856948853},{"id":"https://openalex.org/keywords/superoxide-radicals","display_name":"superoxide","score":0.9940000176429749},{"id":"https://openalex.org/keywords/singlet-oxygen","display_name":"singlet oxygen","score":0.9909999966621399},{"id":"https://openalex.org/keywords/1-3-diphenylisobenzofuran","display_name":"1,3-diphenylisobenzofuran","score":0.9789999723434448},{"id":"https://openalex.org/keywords/viscosity","display_name":"viscosity","score":0.6349999904632568},{"id":"https://openalex.org/keywords/nonsteroidal-anti-inflammatory-drugs","display_name":"nonsteroidal anti-inflammatory drugs","score":0.9459999799728394},{"id":"https://openalex.org/keywords/corticosteroids","display_name":"corticosteroids","score":0.8399999737739563},{"id":"https://openalex.org/keywords/paracetamol","display_name":"paracetamol","score":0.8840000033378601},{"id":"https://openalex.org/keywords/imidazole","display_name":"imidazole","score":0.890999972820282},{"id":"https://openalex.org/keywords/aspirin","display_name":"aspirin","score":0.7089999914169312}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8436777591705322},{"id":"https://openalex.org/C139066938","wikidata":"https://www.wikidata.org/wiki/Q185056","display_name":"Radical","level":2,"score":0.7256584763526917},{"id":"https://openalex.org/C2776268809","wikidata":"https://www.wikidata.org/wiki/Q25581","display_name":"Synovial fluid","level":4,"score":0.6912374496459961},{"id":"https://openalex.org/C2778102346","wikidata":"https://www.wikidata.org/wiki/Q412509","display_name":"Xanthine oxidase","level":3,"score":0.6210189461708069},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5672332644462585},{"id":"https://openalex.org/C2778903070","wikidata":"https://www.wikidata.org/wiki/Q2211240","display_name":"Triamcinolone acetonide","level":2,"score":0.5152645111083984},{"id":"https://openalex.org/C2779700409","wikidata":"https://www.wikidata.org/wiki/Q304285","display_name":"Niflumic acid","level":2,"score":0.41927197575569153},{"id":"https://openalex.org/C2776778087","wikidata":"https://www.wikidata.org/wiki/Q427071","display_name":"Hydroxyl radical","level":3,"score":0.4158400297164917},{"id":"https://openalex.org/C2775844104","wikidata":"https://www.wikidata.org/wiki/Q421342","display_name":"Phenylbutazone","level":2,"score":0.41580110788345337},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.37481844425201416},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.12590950727462769},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.11816617846488953},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.11715847253799438},{"id":"https://openalex.org/C2776164576","wikidata":"https://www.wikidata.org/wiki/Q62736","display_name":"Osteoarthritis","level":3,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000893","descriptor_name":"Anti-Inflammatory Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005609","descriptor_name":"Free Radicals","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D005609","descriptor_name":"Free Radicals","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005609","descriptor_name":"Free Radicals","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013582","descriptor_name":"Synovial Fluid","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D014783","descriptor_name":"Viscosity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066298","descriptor_name":"In Vitro Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0006-2952(78)90390-8","doi":"https://doi.org/10.1016/0006-2952(78)90390-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0006-2952(78)90390-8","pdf_url":null,"source":{"id":"https://openalex.org/S185534594","display_name":"Biochemical Pharmacology","issn_l":"0006-2952","issn":["0006-2952","1873-2968"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical Pharmacology","raw_type":"journal-article"},{"id":"pmid:629812","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/629812","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical pharmacology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.766700029373169,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W304607657","https://openalex.org/W1497458285","https://openalex.org/W1519219147","https://openalex.org/W1553328291","https://openalex.org/W1589390349","https://openalex.org/W1594281994","https://openalex.org/W1940436875","https://openalex.org/W1964308996","https://openalex.org/W1971988464","https://openalex.org/W1973765688","https://openalex.org/W1981486153","https://openalex.org/W1983634320","https://openalex.org/W1984091313","https://openalex.org/W1996236557","https://openalex.org/W2007720933","https://openalex.org/W2030386045","https://openalex.org/W2032497006","https://openalex.org/W2034634199","https://openalex.org/W2036572840","https://openalex.org/W2041527116","https://openalex.org/W2043761572","https://openalex.org/W2045287165","https://openalex.org/W2048571656","https://openalex.org/W2114482761","https://openalex.org/W2156060851","https://openalex.org/W2423841296","https://openalex.org/W2441708394"],"related_works":["https://openalex.org/W2019441712","https://openalex.org/W1983634320","https://openalex.org/W2045781880","https://openalex.org/W2061385800","https://openalex.org/W2276018970","https://openalex.org/W2129867203","https://openalex.org/W2440891450","https://openalex.org/W4232843741","https://openalex.org/W2418561262","https://openalex.org/W2400663247"],"abstract_inverted_index":null,"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}