{"id":"https://openalex.org/W2015269201","doi":"https://doi.org/10.1016/j.bbamem.2007.12.021","title":"VCAM-1 directed immunoliposomes selectively target tumor vasculature in vivo","display_name":"VCAM-1 directed immunoliposomes selectively target tumor vasculature in vivo","publication_year":2008,"publication_date":"2008-01-07","ids":{"openalex":"https://openalex.org/W2015269201","doi":"https://doi.org/10.1016/j.bbamem.2007.12.021","mag":"2015269201","pmid":"https://pubmed.ncbi.nlm.nih.gov/18211818"},"language":"en","primary_location":{"id":"doi:10.1016/j.bbamem.2007.12.021","doi":"https://doi.org/10.1016/j.bbamem.2007.12.021","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbamem.2007.12.021","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0005273607004683/pdf","source":{"id":"https://openalex.org/S4210187475","display_name":"Biochimica et Biophysica Acta (BBA) - Biomembranes","issn_l":"0005-2736","issn":["0005-2736","1879-2642"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - Biomembranes","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2015269201"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.sciencedirect.com/science/article/pii/S0005273607004683/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042681640","display_name":"Sara Gosk","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I135140700","display_name":"University of Bonn","ror":"https://ror.org/041nas322","country_code":"DE","type":"education","lineage":["https://openalex.org/I135140700"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Sara Gosk","raw_affiliation_strings":["University of Bonn, Department of Pharmacy, An der Immenburg 4, 53121 Bonn, Germany. saragosk@gmail.com <saragosk@gmail.com>","University of Bonn, Department of Pharmacy, An der Immenburg 4, 53121 Bonn, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Bonn, Department of Pharmacy, An der Immenburg 4, 53121 Bonn, Germany. saragosk@gmail.com <saragosk@gmail.com>","institution_ids":["https://openalex.org/I135140700"]},{"raw_affiliation_string":"University of Bonn, Department of Pharmacy, An der Immenburg 4, 53121 Bonn, Germany","institution_ids":["https://openalex.org/I135140700"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045394650","display_name":"Torben Moos","orcid":"https://orcid.org/0000-0001-9989-0207","observed_orcids":["https://orcid.org/0000-0001-9989-0207"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Torben Moos","raw_affiliation_strings":["Department of Medical Anatomy, The Panum Institute, University of Copenhagen, Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Anatomy, The Panum Institute, University of Copenhagen, Copenhagen, Denmark","institution_ids":["https://openalex.org/I124055696"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109193481","display_name":"Claudia Gottstein","orcid":"https://orcid.org/0009-0008-1117-8417","observed_orcids":["https://orcid.org/0009-0008-1117-8417"]},"institutions":[{"id":"https://openalex.org/I142207940","display_name":"California NanoSystems Institute","ror":"https://ror.org/00q7fqf35","country_code":"US","type":"facility","lineage":["https://openalex.org/I142207940","https://openalex.org/I154570441","https://openalex.org/I161318765"]},{"id":"https://openalex.org/I154570441","display_name":"University of California, Santa Barbara","ror":"https://ror.org/02t274463","country_code":"US","type":"education","lineage":["https://openalex.org/I154570441"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Claudia Gottstein","raw_affiliation_strings":["University of California Santa Barbara, Department of Chemical Engineering, California NanoSystems Institute, Santa Barbara, CA 93106-5080, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California Santa Barbara, Department of Chemical Engineering, California NanoSystems Institute, Santa Barbara, CA 93106-5080, USA","institution_ids":["https://openalex.org/I142207940","https://openalex.org/I154570441"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031991561","display_name":"Gerd Bendas","orcid":"https://orcid.org/0000-0002-8667-7201","observed_orcids":["https://orcid.org/0000-0002-8667-7201"]},"institutions":[{"id":"https://openalex.org/I135140700","display_name":"University of Bonn","ror":"https://ror.org/041nas322","country_code":"DE","type":"education","lineage":["https://openalex.org/I135140700"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Gerd Bendas","raw_affiliation_strings":["University of Bonn, Department of Pharmacy, An der Immenburg 4, 53121 Bonn, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Bonn, Department of Pharmacy, An der Immenburg 4, 53121 Bonn, Germany","institution_ids":["https://openalex.org/I135140700"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5042681640"],"corresponding_institution_ids":["https://openalex.org/I135140700"],"apc_list":{"value":3870,"currency":"USD","value_usd":3870},"apc_paid":null,"fwci":3.5035,"has_fulltext":true,"cited_by_count":161,"citation_normalized_percentile":{"value":0.93227871,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"1778","issue":"4","first_page":"854","last_page":"863"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10422","display_name":"Angiogenesis and VEGF in Cancer","score":0.003599999938160181,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vcam-1","display_name":"VCAM-1","score":0.9509999752044678},{"id":"https://openalex.org/keywords/immunoliposomes","display_name":"immunoliposomes","score":0.9869999885559082},{"id":"https://openalex.org/keywords/tumor-vasculature-targeting","display_name":"tumor vasculature targeting","score":0.9539999961853027},{"id":"https://openalex.org/keywords/polyethylene-glycol","display_name":"polyethylene glycol","score":0.5979999899864197},{"id":"https://openalex.org/keywords/endothelial-targeting","display_name":"endothelial targeting","score":0.6779999732971191},{"id":"https://openalex.org/keywords/tumor-xenografts","display_name":"tumor xenografts","score":0.7720000147819519},{"id":"https://openalex.org/keywords/tissue-distribution","display_name":"tissue distribution","score":0.699999988079071},{"id":"https://openalex.org/keywords/tumor-accumulation","display_name":"tumor accumulation","score":0.47999998927116394},{"id":"https://openalex.org/keywords/endothelial-function","display_name":"endothelial function","score":0.5220000147819519},{"id":"https://openalex.org/keywords/drug-delivery-systems","display_name":"drug delivery systems","score":0.699999988079071},{"id":"https://openalex.org/keywords/cancer-therapy","display_name":"cancer therapy","score":0.5360000133514404}],"concepts":[{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.83135986328125},{"id":"https://openalex.org/C2777807558","wikidata":"https://www.wikidata.org/wiki/Q4914764","display_name":"Biodistribution","level":3,"score":0.6990191340446472},{"id":"https://openalex.org/C185154212","wikidata":"https://www.wikidata.org/wiki/Q410454","display_name":"Liposome","level":2,"score":0.6738285422325134},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.5825293064117432},{"id":"https://openalex.org/C2776985958","wikidata":"https://www.wikidata.org/wiki/Q14901827","display_name":"VCAM-1","level":4,"score":0.5584720969200134},{"id":"https://openalex.org/C16224149","wikidata":"https://www.wikidata.org/wiki/Q187637","display_name":"Cell adhesion molecule","level":2,"score":0.48354268074035645},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.46214520931243896},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.42341914772987366},{"id":"https://openalex.org/C2780931953","wikidata":"https://www.wikidata.org/wiki/Q9371","display_name":"Spleen","level":2,"score":0.4105134904384613},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.35468733310699463},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.32224518060684204},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.31546199321746826},{"id":"https://openalex.org/C185946421","wikidata":"https://www.wikidata.org/wiki/Q3146527","display_name":"ICAM-1","level":3,"score":0.26913854479789734},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2683483958244324},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.21051833033561707},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008081","descriptor_name":"Liposomes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008819","descriptor_name":"Mice, Nude","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":true},{"descriptor_ui":"D009928","descriptor_name":"Organ Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010316","descriptor_name":"Particle Size","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012235","descriptor_name":"Rhodamines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019010","descriptor_name":"Vascular Cell Adhesion Molecule-1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.bbamem.2007.12.021","doi":"https://doi.org/10.1016/j.bbamem.2007.12.021","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbamem.2007.12.021","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0005273607004683/pdf","source":{"id":"https://openalex.org/S4210187475","display_name":"Biochimica et Biophysica Acta (BBA) - Biomembranes","issn_l":"0005-2736","issn":["0005-2736","1879-2642"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - Biomembranes","raw_type":"journal-article"},{"id":"pmid:18211818","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18211818","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et biophysica acta","raw_type":"Journal Article"},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/d38a4100-ee15-11dd-bf70-000ea68e967b","doi":null,"is_oa":false,"landing_page_url":"https://researchprofiles.ku.dk/da/publications/d38a4100-ee15-11dd-bf70-000ea68e967b","pdf_url":null,"source":{"id":"https://openalex.org/S4306401983","display_name":"Research at the University of Copenhagen (University of Copenhagen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I124055696","host_organization_name":"University of Copenhagen","host_organization_lineage":["https://openalex.org/I124055696"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Gosk, S, Moos, T, Gottstein, C & Bendas, G 2008, 'VCAM-1 directed immunoliposomes selectively target tumor vasculature in vivo', Biochimica et Biophysica Acta - Biomembranes, vol. 1778, no. 4, pp. 854-863.","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1016/j.bbamem.2007.12.021","doi":"https://doi.org/10.1016/j.bbamem.2007.12.021","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbamem.2007.12.021","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0005273607004683/pdf","source":{"id":"https://openalex.org/S4210187475","display_name":"Biochimica et Biophysica Acta (BBA) - Biomembranes","issn_l":"0005-2736","issn":["0005-2736","1879-2642"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - Biomembranes","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2015269201.pdf","grobid_xml":"https://content.openalex.org/works/W2015269201.grobid-xml"},"referenced_works_count":59,"referenced_works":["https://openalex.org/W7317053","https://openalex.org/W27984734","https://openalex.org/W169646064","https://openalex.org/W1547687419","https://openalex.org/W1579297325","https://openalex.org/W1593511862","https://openalex.org/W1635858559","https://openalex.org/W1641628118","https://openalex.org/W1969402650","https://openalex.org/W1977793874","https://openalex.org/W1978002868","https://openalex.org/W1982942806","https://openalex.org/W1987125650","https://openalex.org/W1993342139","https://openalex.org/W2001720727","https://openalex.org/W2012470499","https://openalex.org/W2013308107","https://openalex.org/W2018227730","https://openalex.org/W2022788095","https://openalex.org/W2028294113","https://openalex.org/W2028835321","https://openalex.org/W2035798792","https://openalex.org/W2039097438","https://openalex.org/W2046781132","https://openalex.org/W2050085273","https://openalex.org/W2058729706","https://openalex.org/W2063170675","https://openalex.org/W2068508373","https://openalex.org/W2069808711","https://openalex.org/W2071080861","https://openalex.org/W2076684752","https://openalex.org/W2078516817","https://openalex.org/W2082885247","https://openalex.org/W2085882810","https://openalex.org/W2087220239","https://openalex.org/W2089929639","https://openalex.org/W2102131116","https://openalex.org/W2103036523","https://openalex.org/W2103692236","https://openalex.org/W2117895485","https://openalex.org/W2121357123","https://openalex.org/W2129234881","https://openalex.org/W2134758761","https://openalex.org/W2141151991","https://openalex.org/W2142116055","https://openalex.org/W2148809263","https://openalex.org/W2150595969","https://openalex.org/W2152574565","https://openalex.org/W2156587383","https://openalex.org/W2156969927","https://openalex.org/W2159577992","https://openalex.org/W2169794253","https://openalex.org/W2171554134","https://openalex.org/W2320555543","https://openalex.org/W2401810979","https://openalex.org/W2414615250","https://openalex.org/W2418072892","https://openalex.org/W4230026896","https://openalex.org/W6606960461"],"related_works":["https://openalex.org/W244407940","https://openalex.org/W2320555543","https://openalex.org/W2069808711","https://openalex.org/W3022467570","https://openalex.org/W2018760532","https://openalex.org/W71258637","https://openalex.org/W2137347544","https://openalex.org/W2581220805","https://openalex.org/W1987125650","https://openalex.org/W2790186561"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":13},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":11},{"year":2018,"cited_by_count":10},{"year":2017,"cited_by_count":14},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":14},{"year":2013,"cited_by_count":10},{"year":2012,"cited_by_count":8}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}