{"id":"https://openalex.org/W2015249461","doi":"https://doi.org/10.1152/ajpgi.00365.2003","title":"Folic acid-mediated inhibition of serum-induced activation of EGFR promoter in colon cancer cells","display_name":"Folic acid-mediated inhibition of serum-induced activation of EGFR promoter in colon cancer cells","publication_year":2004,"publication_date":"2004-04-12","ids":{"openalex":"https://openalex.org/W2015249461","doi":"https://doi.org/10.1152/ajpgi.00365.2003","mag":"2015249461","pmid":"https://pubmed.ncbi.nlm.nih.gov/15075253"},"language":"en","primary_location":{"id":"doi:10.1152/ajpgi.00365.2003","doi":"https://doi.org/10.1152/ajpgi.00365.2003","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajpgi.00365.2003","pdf_url":null,"source":{"id":"https://openalex.org/S34136372","display_name":"American Journal of Physiology-Gastrointestinal and Liver Physiology","issn_l":"0193-1857","issn":["0193-1857","1522-1547"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Gastrointestinal and Liver Physiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010450809","display_name":"Kiran K. Nagothu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799886695","display_name":"Veterans Health Administration","ror":"https://ror.org/05eq41471","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kiran K. Nagothu","raw_affiliation_strings":["Veterans Affairs Medical Center, Detroit, Michigan 48201, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Veterans Affairs Medical Center, Detroit, Michigan 48201, USA","institution_ids":["https://openalex.org/I2799886695"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091506580","display_name":"Arun K. Rishi","orcid":"https://orcid.org/0000-0001-8611-9923","observed_orcids":["https://orcid.org/0000-0001-8611-9923"]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]},{"id":"https://openalex.org/I4210089364","display_name":"John D. Dingell VA Medical Center","ror":"https://ror.org/0057s8s52","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210089364","https://openalex.org/I4210127612"]},{"id":"https://openalex.org/I4210090317","display_name":"The Barbara Ann Karmanos Cancer Institute","ror":"https://ror.org/00ee40h97","country_code":"US","type":"facility","lineage":["https://openalex.org/I2800590384","https://openalex.org/I4210090317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Arun K. Rishi","raw_affiliation_strings":["","Veterans Affairs Medical Center, Karmanos Cancer Institute, and Department of Internal Medicine, Wayne State University School of Medicine, Detroit, Michigan 48201"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]},{"raw_affiliation_string":"Veterans Affairs Medical Center, Karmanos Cancer Institute, and Department of Internal Medicine, Wayne State University School of Medicine, Detroit, Michigan 48201","institution_ids":["https://openalex.org/I185443292","https://openalex.org/I4210089364","https://openalex.org/I4210090317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036184604","display_name":"Richard Jaszewski","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]},{"id":"https://openalex.org/I4210089364","display_name":"John D. Dingell VA Medical Center","ror":"https://ror.org/0057s8s52","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210089364","https://openalex.org/I4210127612"]},{"id":"https://openalex.org/I4210090317","display_name":"The Barbara Ann Karmanos Cancer Institute","ror":"https://ror.org/00ee40h97","country_code":"US","type":"facility","lineage":["https://openalex.org/I2800590384","https://openalex.org/I4210090317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard Jaszewski","raw_affiliation_strings":["","Veterans Affairs Medical Center, Karmanos Cancer Institute, and Department of Internal Medicine, Wayne State University School of Medicine, Detroit, Michigan 48201"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]},{"raw_affiliation_string":"Veterans Affairs Medical Center, Karmanos Cancer Institute, and Department of Internal Medicine, Wayne State University School of Medicine, Detroit, Michigan 48201","institution_ids":["https://openalex.org/I185443292","https://openalex.org/I4210089364","https://openalex.org/I4210090317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010114692","display_name":"\u00d6mer K\u00fc\u00e7\u00fck","orcid":"https://orcid.org/0000-0002-4755-0507","observed_orcids":["https://orcid.org/0000-0002-4755-0507"]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]},{"id":"https://openalex.org/I4210089364","display_name":"John D. Dingell VA Medical Center","ror":"https://ror.org/0057s8s52","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210089364","https://openalex.org/I4210127612"]},{"id":"https://openalex.org/I4210090317","display_name":"The Barbara Ann Karmanos Cancer Institute","ror":"https://ror.org/00ee40h97","country_code":"US","type":"facility","lineage":["https://openalex.org/I2800590384","https://openalex.org/I4210090317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Omer Kucuk","raw_affiliation_strings":["","Veterans Affairs Medical Center, Karmanos Cancer Institute, and Department of Internal Medicine, Wayne State University School of Medicine, Detroit, Michigan 48201"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]},{"raw_affiliation_string":"Veterans Affairs Medical Center, Karmanos Cancer Institute, and Department of Internal Medicine, Wayne State University School of Medicine, Detroit, Michigan 48201","institution_ids":["https://openalex.org/I185443292","https://openalex.org/I4210089364","https://openalex.org/I4210090317"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5029214095","display_name":"Adhip P.N. Majumdar","orcid":"https://orcid.org/0000-0002-6413-5102","observed_orcids":["https://orcid.org/0000-0002-6413-5102"]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]},{"id":"https://openalex.org/I4210089364","display_name":"John D. Dingell VA Medical Center","ror":"https://ror.org/0057s8s52","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210089364","https://openalex.org/I4210127612"]},{"id":"https://openalex.org/I4210090317","display_name":"The Barbara Ann Karmanos Cancer Institute","ror":"https://ror.org/00ee40h97","country_code":"US","type":"facility","lineage":["https://openalex.org/I2800590384","https://openalex.org/I4210090317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Adhip P. N. Majumdar","raw_affiliation_strings":["","Veterans Affairs Medical Center, Karmanos Cancer Institute, and Department of Internal Medicine, Wayne State University School of Medicine, Detroit, Michigan 48201"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]},{"raw_affiliation_string":"Veterans Affairs Medical Center, Karmanos Cancer Institute, and Department of Internal Medicine, Wayne State University School of Medicine, Detroit, Michigan 48201","institution_ids":["https://openalex.org/I185443292","https://openalex.org/I4210089364","https://openalex.org/I4210090317"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.7445,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":{"value":0.82997481,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"287","issue":"3","first_page":"G541","last_page":"G546"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10499","display_name":"Folate and B Vitamins Research","score":0.9336000084877014,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10499","display_name":"Folate and B Vitamins Research","score":0.9336000084877014,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.03449999913573265,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11067","display_name":"Colorectal Cancer Treatments and Studies","score":0.013199999928474426,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/folic-acid","display_name":"folic acid","score":1.0},{"id":"https://openalex.org/keywords/epidermal-growth-factor-receptor","display_name":"epidermal growth factor receptor","score":0.9380000233650208},{"id":"https://openalex.org/keywords/egfr-promoter","display_name":"EGFR promoter","score":0.7850000262260437},{"id":"https://openalex.org/keywords/promoter-methylation","display_name":"promoter methylation","score":0.7450000047683716},{"id":"https://openalex.org/keywords/5-methyltetrahydrofolate","display_name":"5-methyltetrahydrofolate","score":0.9520000219345093},{"id":"https://openalex.org/keywords/dihydrofolate","display_name":"dihydrofolate","score":0.7929999828338623},{"id":"https://openalex.org/keywords/tetrahydrofolate","display_name":"tetrahydrofolate","score":0.9919999837875366},{"id":"https://openalex.org/keywords/colorectal-cancer","display_name":"colorectal cancer","score":0.5659999847412109},{"id":"https://openalex.org/keywords/chemoprevention","display_name":"chemoprevention","score":0.8889999985694885},{"id":"https://openalex.org/keywords/hct116-cells","display_name":"HCT116 cells","score":0.8679999709129333},{"id":"https://openalex.org/keywords/c-fos-promoter","display_name":"c-fos promoter","score":0.7459999918937683},{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.8889999985694885}],"concepts":[{"id":"https://openalex.org/C2992130864","wikidata":"https://www.wikidata.org/wiki/Q127060","display_name":"Folic acid","level":2,"score":0.6127234101295471},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.6102783679962158},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5718947649002075},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5570095777511597},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5064431428909302},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.34625327587127686},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3132447600364685}],"mesh":[{"descriptor_ui":"D000077209","descriptor_name":"Decitabine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000964","descriptor_name":"Antimetabolites, Antineoplastic","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D001374","descriptor_name":"Azacitidine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D001374","descriptor_name":"Azacitidine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003110","descriptor_name":"Colonic Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D003110","descriptor_name":"Colonic Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005492","descriptor_name":"Folic Acid","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008156","descriptor_name":"Luciferases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D013763","descriptor_name":"Tetrahydrofolates","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D014162","descriptor_name":"Transfection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015153","descriptor_name":"Blotting, Western","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016895","descriptor_name":"Culture Media, Serum-Free","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017931","descriptor_name":"DNA Primers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020133","descriptor_name":"Reverse Transcriptase Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066246","descriptor_name":"ErbB Receptors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1152/ajpgi.00365.2003","doi":"https://doi.org/10.1152/ajpgi.00365.2003","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajpgi.00365.2003","pdf_url":null,"source":{"id":"https://openalex.org/S34136372","display_name":"American Journal of Physiology-Gastrointestinal and Liver Physiology","issn_l":"0193-1857","issn":["0193-1857","1522-1547"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Gastrointestinal and Liver Physiology","raw_type":"journal-article"},{"id":"pmid:15075253","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15075253","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of physiology. Gastrointestinal and liver physiology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1215796749","display_name":null,"funder_award_id":"AG-14343","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G5852701817","display_name":"The Aging Gut: Regulation of Cell Proliferation","funder_award_id":"R01AG014343","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"}],"funders":[{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W70353535","https://openalex.org/W1852277943","https://openalex.org/W1968821239","https://openalex.org/W1972903383","https://openalex.org/W1984004239","https://openalex.org/W1984181818","https://openalex.org/W1994465394","https://openalex.org/W1997619806","https://openalex.org/W2011006722","https://openalex.org/W2029008381","https://openalex.org/W2029080338","https://openalex.org/W2029632256","https://openalex.org/W2045403592","https://openalex.org/W2055627027","https://openalex.org/W2081069977","https://openalex.org/W2085300889","https://openalex.org/W2104283475","https://openalex.org/W2109856812","https://openalex.org/W2113055732","https://openalex.org/W2121831273","https://openalex.org/W2123206362","https://openalex.org/W2124040125","https://openalex.org/W2129930708","https://openalex.org/W2144177115","https://openalex.org/W2151395261","https://openalex.org/W2159657430","https://openalex.org/W2234755759","https://openalex.org/W2323474848","https://openalex.org/W2342417061"],"related_works":["https://openalex.org/W2342417061","https://openalex.org/W2145952427","https://openalex.org/W100813427","https://openalex.org/W2736011383","https://openalex.org/W2023462823","https://openalex.org/W2398979536","https://openalex.org/W2252719885","https://openalex.org/W2292028911","https://openalex.org/W2067391083","https://openalex.org/W2740093555"],"abstract_inverted_index":{"Although":[0],"accumulating":[1],"evidence":[2],"suggests":[3],"a":[4,159],"chemopreventive":[5],"role":[6],"for":[7,105,118,238],"folic":[8],"acid":[9],"(FA)":[10],"in":[11,37,82,127,226,244],"colorectal":[12,245],"carcinogenesis,":[13],"the":[14,27,44,79,83,110,128,153],"underlying":[15],"mechanisms":[16],"are":[17],"largely":[18],"unknown.":[19],"Previously,":[20],"we":[21,52],"reported":[22],"that":[23,216],"supplemental":[24,60,176],"FA":[25,48,61,97,136,177,217],"inhibits":[26],"expression":[28,204],"and":[29,56,69,75,116,147,166,178,202,218],"activation":[30,77,183],"of":[31,78,100,132,152,162,170,184,195,198,241],"epidermal":[32],"growth":[33],"factor":[34],"receptor":[35],"(EGFR)":[36],"colon":[38,85,227],"cancer":[39,86,228],"cell":[40,87],"lines.":[41],"To":[42],"determine":[43],"mechanism(s)":[45],"by":[46,175,190,211,230],"which":[47,171],"affects":[49],"EGFR":[50,80,111,144,163,199,203,223],"function,":[51],"have":[53],"examined":[54],"whether":[55],"to":[57,155],"what":[58],"extent":[59],"or":[62,94,98,125,130],"its":[63,101,140,148,167,219],"metabolites":[64,102,141],"5-methyltetrahydrofolate":[65],"(MTF),":[66],"dihydrofolate":[67],"(DF),":[68],"tetrahydrofolate":[70],"(TF)":[71],"will":[72],"modulate":[73],"basal":[74],"serum-induced":[76,182],"promoter":[81,112,145,164,186,200,224],"HCT-116":[84,89],"line.":[88],"cells":[90,154,229],"were":[91,172],"preincubated":[92],"with":[93,109,121],"without":[95],"(control)":[96],"one":[99],"(10":[103],"microg/ml)":[104],"48":[106,119],"h,":[107],"transfected":[108],"luciferase":[113],"reporter":[114],"construct,":[115],"incubated":[117],"h":[120],"FA,":[122],"DF,":[123],"TF,":[124],"5-MTF":[126,221],"absence":[129],"presence":[131],"10%":[133,156],"FBS.":[134],"Supplemental":[135],"as":[137,139],"well":[138],"markedly":[142],"inhibited":[143,210],"activity":[146,165,187,201,225],"methylation":[149,208],"status.":[150],"Exposure":[151],"FBS":[157],"caused":[158],"marked":[160],"stimulation":[161,197],"expression,":[168],"both":[169],"greatly":[173],"abrogated":[174],"5-MTF.":[179,191],"In":[180],"contrast,":[181],"c-fos":[185],"was":[188,205,209],"unaffected":[189],"The":[192],"5-MTF-induced":[193],"inhibition":[194,240],"serum-mediated":[196],"reversed":[206],"when":[207],"5-aza-2'-deoxycytidine.":[212],"Our":[213],"data":[214],"suggest":[215],"metabolite":[220],"inhibit":[222],"enhancing":[231],"methylation.":[232],"This":[233],"could":[234],"partly":[235],"be":[236],"responsible":[237],"FA-mediated":[239],"growth-related":[242],"processes":[243],"neoplasia.":[246]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
