{"id":"https://openalex.org/W2015200369","doi":"https://doi.org/10.1007/s00418-005-0089-6","title":"The normal cellular prion protein (PrPc) is strongly expressed in bovine endocrine pancreas","display_name":"The normal cellular prion protein (PrPc) is strongly expressed in bovine endocrine pancreas","publication_year":2005,"publication_date":"2005-10-05","ids":{"openalex":"https://openalex.org/W2015200369","doi":"https://doi.org/10.1007/s00418-005-0089-6","mag":"2015200369","pmid":"https://pubmed.ncbi.nlm.nih.gov/16208484"},"language":"en","primary_location":{"id":"doi:10.1007/s00418-005-0089-6","doi":"https://doi.org/10.1007/s00418-005-0089-6","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00418-005-0089-6","pdf_url":null,"source":{"id":"https://openalex.org/S78725770","display_name":"Histochemistry and Cell Biology","issn_l":"0948-6143","issn":["0948-6143","1432-119X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Histochemistry and Cell Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109944633","display_name":"W. M. Amselgruber","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I110079840","display_name":"University of Hohenheim","ror":"https://ror.org/00b1c9541","country_code":"DE","type":"education","lineage":["https://openalex.org/I110079840"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"W.M. Amselgruber","raw_affiliation_strings":["Institute of Anatomy and Physiology, University of Hohenheim, Fruhwirthstr. 35, 70599, Stuttgart, Germany. amselgru@uni-hohenheim.de","University of Hohenheim >  >  >  >"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Anatomy and Physiology, University of Hohenheim, Fruhwirthstr. 35, 70599, Stuttgart, Germany. amselgru@uni-hohenheim.de","institution_ids":["https://openalex.org/I110079840"]},{"raw_affiliation_string":"University of Hohenheim >  >  >  >","institution_ids":["https://openalex.org/I110079840"]}]},{"author_position":"middle","author":{"id":null,"display_name":"M. B\u00fcttner","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. B\u00fcttner","raw_affiliation_strings":["Bavarian Health and Food Safety Authority, Veterin\u00e4rstr. 2, 85764, Oberschlei\u00dfheim, Germany","Bavarian Health and Food Safety Authority"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bavarian Health and Food Safety Authority, Veterin\u00e4rstr. 2, 85764, Oberschlei\u00dfheim, Germany","institution_ids":[]},{"raw_affiliation_string":"Bavarian Health and Food Safety Authority","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"T. Schlegel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I110079840","display_name":"University of Hohenheim","ror":"https://ror.org/00b1c9541","country_code":"DE","type":"education","lineage":["https://openalex.org/I110079840"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"T. Schlegel","raw_affiliation_strings":["Institute of Anatomy and Physiology, University of Hohenheim, Fruhwirthstr. 35, 70599, Stuttgart, Germany","University of Hohenheim >  >  >  >"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Anatomy and Physiology, University of Hohenheim, Fruhwirthstr. 35, 70599, Stuttgart, Germany","institution_ids":["https://openalex.org/I110079840"]},{"raw_affiliation_string":"University of Hohenheim >  >  >  >","institution_ids":["https://openalex.org/I110079840"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016259438","display_name":"Markus W. Schweiger","orcid":"https://orcid.org/0000-0002-8197-3044","observed_orcids":["https://orcid.org/0000-0002-8197-3044"]},"institutions":[{"id":"https://openalex.org/I110079840","display_name":"University of Hohenheim","ror":"https://ror.org/00b1c9541","country_code":"DE","type":"education","lineage":["https://openalex.org/I110079840"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"M. Schweiger","raw_affiliation_strings":["Institute of Anatomy and Physiology, University of Hohenheim, Fruhwirthstr. 35, 70599, Stuttgart, Germany","University of Hohenheim >  >  >  >"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Anatomy and Physiology, University of Hohenheim, Fruhwirthstr. 35, 70599, Stuttgart, Germany","institution_ids":["https://openalex.org/I110079840"]},{"raw_affiliation_string":"University of Hohenheim >  >  >  >","institution_ids":["https://openalex.org/I110079840"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048649189","display_name":"Eberhardt Pfaff","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1310048521","display_name":"Friedrich-Loeffler-Institut","ror":"https://ror.org/025fw7a54","country_code":"DE","type":"government","lineage":["https://openalex.org/I1310048521","https://openalex.org/I2801963157"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"E. Pfaff","raw_affiliation_strings":["Friedrich-Loeffler-Institute, Institute for Immunology, Paul Ehrlich-Str. 28, 72076, T\u00fcbingen, Germany","Institute for Immunology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Friedrich-Loeffler-Institute, Institute for Immunology, Paul Ehrlich-Str. 28, 72076, T\u00fcbingen, Germany","institution_ids":["https://openalex.org/I1310048521"]},{"raw_affiliation_string":"Institute for Immunology","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5109944633"],"corresponding_institution_ids":["https://openalex.org/I110079840"],"apc_list":{"value":2990,"currency":"USD","value_usd":2990},"apc_paid":null,"fwci":0.583,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.60345642,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"125","issue":"4","first_page":"441","last_page":"448"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11335","display_name":"Prion Diseases and Protein Misfolding","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11335","display_name":"Prion Diseases and Protein Misfolding","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11305","display_name":"Amyloidosis: Diagnosis, Treatment, Outcomes","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cellular-prion-protein","display_name":"cellular prion protein","score":0.984000027179718},{"id":"https://openalex.org/keywords/islet-cells","display_name":"pancreatic endocrine cells","score":0.8999999761581421},{"id":"https://openalex.org/keywords/chromogranin-b","display_name":"chromogranin B","score":0.7689999938011169},{"id":"https://openalex.org/keywords/chromogranin-a","display_name":"chromogranin A","score":0.9980000257492065},{"id":"https://openalex.org/keywords/pancreatic-alpha-cells","display_name":"alpha cells","score":0.5419999957084656},{"id":"https://openalex.org/keywords/prion-disease","display_name":"prion disease","score":0.9129999876022339},{"id":"https://openalex.org/keywords/iatrogenic-transmission","display_name":"iatrogenic transmission","score":0.8579999804496765},{"id":"https://openalex.org/keywords/gene-expression-regulation","display_name":"gene expression regulation","score":0.49900001287460327}],"concepts":[{"id":"https://openalex.org/C77231918","wikidata":"https://www.wikidata.org/wiki/Q3698322","display_name":"Chromogranin A","level":3,"score":0.8770076632499695},{"id":"https://openalex.org/C103395026","wikidata":"https://www.wikidata.org/wiki/Q5380231","display_name":"Enteroendocrine cell","level":4,"score":0.7329574823379517},{"id":"https://openalex.org/C2778764654","wikidata":"https://www.wikidata.org/wiki/Q9618","display_name":"Pancreas","level":2,"score":0.6419804096221924},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6356872320175171},{"id":"https://openalex.org/C2778108375","wikidata":"https://www.wikidata.org/wiki/Q246978","display_name":"Pancreatic polypeptide","level":4,"score":0.527782142162323},{"id":"https://openalex.org/C46699223","wikidata":"https://www.wikidata.org/wiki/Q11078","display_name":"Endocrine system","level":3,"score":0.5195643901824951},{"id":"https://openalex.org/C2776297358","wikidata":"https://www.wikidata.org/wiki/Q407166","display_name":"Somatostatin","level":2,"score":0.5189406871795654},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.48392802476882935},{"id":"https://openalex.org/C2779855799","wikidata":"https://www.wikidata.org/wiki/Q728309","display_name":"Pancreatic islets","level":4,"score":0.4802249073982239},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.34280139207839966},{"id":"https://openalex.org/C2778563252","wikidata":"https://www.wikidata.org/wiki/Q170617","display_name":"Glucagon","level":3,"score":0.3411221504211426},{"id":"https://openalex.org/C165220095","wikidata":"https://www.wikidata.org/wiki/Q207524","display_name":"Islet","level":3,"score":0.3403123915195465},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.33566850423812866},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.33462977409362793},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.24589210748672485},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.19607800245285034},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.18610447645187378},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.13120439648628235}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005333","descriptor_name":"Fetus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007515","descriptor_name":"Islets of Langerhans","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D007515","descriptor_name":"Islets of Langerhans","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018621","descriptor_name":"PrPC Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D053378","descriptor_name":"Chromogranin B","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D053379","descriptor_name":"Chromogranin A","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1007/s00418-005-0089-6","doi":"https://doi.org/10.1007/s00418-005-0089-6","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00418-005-0089-6","pdf_url":null,"source":{"id":"https://openalex.org/S78725770","display_name":"Histochemistry and Cell Biology","issn_l":"0948-6143","issn":["0948-6143","1432-119X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Histochemistry and Cell Biology","raw_type":"journal-article"},{"id":"pmid:16208484","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16208484","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Histochemistry and cell biology","raw_type":"Journal Article"},{"id":"pmh:oai:www.openagrar.de:openagrar_mods_00012342","doi":null,"is_oa":false,"landing_page_url":"http://link.springer.com/article/10.1007%2Fs00418-005-0089-6","pdf_url":null,"source":{"id":"https://openalex.org/S7407055137","display_name":"OpenAgrar","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.824400007724762}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":66,"referenced_works":["https://openalex.org/W149247114","https://openalex.org/W153029887","https://openalex.org/W1573809350","https://openalex.org/W1637145043","https://openalex.org/W1704732331","https://openalex.org/W1827691446","https://openalex.org/W1935439593","https://openalex.org/W1964652622","https://openalex.org/W1966329329","https://openalex.org/W1966457518","https://openalex.org/W1975802239","https://openalex.org/W1979112354","https://openalex.org/W1982040954","https://openalex.org/W1986274933","https://openalex.org/W1987268193","https://openalex.org/W1988945924","https://openalex.org/W1990496336","https://openalex.org/W1992659255","https://openalex.org/W2002174350","https://openalex.org/W2002527726","https://openalex.org/W2003653067","https://openalex.org/W2006810449","https://openalex.org/W2010184287","https://openalex.org/W2010388034","https://openalex.org/W2011927539","https://openalex.org/W2012629717","https://openalex.org/W2017800240","https://openalex.org/W2019498875","https://openalex.org/W2022680168","https://openalex.org/W2024632362","https://openalex.org/W2025328816","https://openalex.org/W2034223405","https://openalex.org/W2035009661","https://openalex.org/W2044942478","https://openalex.org/W2065903778","https://openalex.org/W2080718684","https://openalex.org/W2092121728","https://openalex.org/W2092363623","https://openalex.org/W2094279987","https://openalex.org/W2094849506","https://openalex.org/W2095193325","https://openalex.org/W2098103936","https://openalex.org/W2098576607","https://openalex.org/W2107605597","https://openalex.org/W2110739021","https://openalex.org/W2117580648","https://openalex.org/W2119749560","https://openalex.org/W2119979452","https://openalex.org/W2129250361","https://openalex.org/W2131020698","https://openalex.org/W2137462514","https://openalex.org/W2142003218","https://openalex.org/W2147465611","https://openalex.org/W2150441035","https://openalex.org/W2150497169","https://openalex.org/W2153969361","https://openalex.org/W2154411206","https://openalex.org/W2160013746","https://openalex.org/W2160995014","https://openalex.org/W2162594375","https://openalex.org/W2163749649","https://openalex.org/W2164123708","https://openalex.org/W2168392699","https://openalex.org/W2413492794","https://openalex.org/W2469440036","https://openalex.org/W4242917162"],"related_works":["https://openalex.org/W2024351041","https://openalex.org/W2132849161","https://openalex.org/W2057105086","https://openalex.org/W2593071926","https://openalex.org/W116063470","https://openalex.org/W2036487855","https://openalex.org/W4295107409","https://openalex.org/W1981995797","https://openalex.org/W3185363452","https://openalex.org/W2000999460"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2019,"cited_by_count":1},{"year":2014,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}