{"id":"https://openalex.org/W2015198948","doi":"https://doi.org/10.1016/0161-5890(91)90016-d","title":"Mapping of two immunodominant structures on human interferon alpha 2c and their role in binding to cells","display_name":"Mapping of two immunodominant structures on human interferon alpha 2c and their role in binding to cells","publication_year":1991,"publication_date":"1991-11-01","ids":{"openalex":"https://openalex.org/W2015198948","doi":"https://doi.org/10.1016/0161-5890(91)90016-d","mag":"2015198948","pmid":"https://pubmed.ncbi.nlm.nih.gov/1720506"},"language":"en","primary_location":{"id":"doi:10.1016/0161-5890(91)90016-d","doi":"https://doi.org/10.1016/0161-5890(91)90016-d","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0161-5890(91)90016-d","pdf_url":null,"source":{"id":"https://openalex.org/S92126311","display_name":"Molecular Immunology","issn_l":"0161-5890","issn":["0161-5890","1872-9142"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Immunology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007461691","display_name":"PETER KONTSEK","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I207624831","display_name":"Slovak Academy of Sciences","ror":"https://ror.org/03h7qq074","country_code":"SK","type":"government","lineage":["https://openalex.org/I207624831"]},{"id":"https://openalex.org/I4210164364","display_name":"Institute of Virology of the Slovak Academy of Sciences","ror":"https://ror.org/04xrjem68","country_code":"SK","type":"facility","lineage":["https://openalex.org/I207624831","https://openalex.org/I4210123996","https://openalex.org/I4210164364"]}],"countries":["SK"],"is_corresponding":false,"raw_author_name":"Peter Kontsek","raw_affiliation_strings":["Institute of Virology, Slovak Academy of Sciences, Bratislava, Czech","Institute of Virology, Slovak Academy of Sciences, 842 46 Bratislava, Czech and SlovakCzech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Virology, Slovak Academy of Sciences, Bratislava, Czech","institution_ids":["https://openalex.org/I207624831","https://openalex.org/I4210164364"]},{"raw_affiliation_string":"Institute of Virology, Slovak Academy of Sciences, 842 46 Bratislava, Czech and SlovakCzech Republic","institution_ids":["https://openalex.org/I207624831","https://openalex.org/I4210164364"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008391382","display_name":"adislav Borecky","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I207624831","display_name":"Slovak Academy of Sciences","ror":"https://ror.org/03h7qq074","country_code":"SK","type":"government","lineage":["https://openalex.org/I207624831"]},{"id":"https://openalex.org/I4210164364","display_name":"Institute of Virology of the Slovak Academy of Sciences","ror":"https://ror.org/04xrjem68","country_code":"SK","type":"facility","lineage":["https://openalex.org/I207624831","https://openalex.org/I4210123996","https://openalex.org/I4210164364"]}],"countries":["SK"],"is_corresponding":false,"raw_author_name":"adislav Borecky","raw_affiliation_strings":["Institute of Virology, Slovak Academy of Sciences, 842 46 Bratislava, Czech and SlovakCzech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Virology, Slovak Academy of Sciences, 842 46 Bratislava, Czech and SlovakCzech Republic","institution_ids":["https://openalex.org/I207624831","https://openalex.org/I4210164364"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028810504","display_name":"Eva Kontsekov\u00e1","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I207624831","display_name":"Slovak Academy of Sciences","ror":"https://ror.org/03h7qq074","country_code":"SK","type":"government","lineage":["https://openalex.org/I207624831"]},{"id":"https://openalex.org/I4210164364","display_name":"Institute of Virology of the Slovak Academy of Sciences","ror":"https://ror.org/04xrjem68","country_code":"SK","type":"facility","lineage":["https://openalex.org/I207624831","https://openalex.org/I4210123996","https://openalex.org/I4210164364"]}],"countries":["SK"],"is_corresponding":false,"raw_author_name":"Eva Kontsekova","raw_affiliation_strings":["Institute of Virology, Slovak Academy of Sciences, 842 46 Bratislava, Czech and SlovakCzech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Virology, Slovak Academy of Sciences, 842 46 Bratislava, Czech and SlovakCzech Republic","institution_ids":["https://openalex.org/I207624831","https://openalex.org/I4210164364"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038707465","display_name":"Ivana Macikov","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I207624831","display_name":"Slovak Academy of Sciences","ror":"https://ror.org/03h7qq074","country_code":"SK","type":"government","lineage":["https://openalex.org/I207624831"]},{"id":"https://openalex.org/I4210164364","display_name":"Institute of Virology of the Slovak Academy of Sciences","ror":"https://ror.org/04xrjem68","country_code":"SK","type":"facility","lineage":["https://openalex.org/I207624831","https://openalex.org/I4210123996","https://openalex.org/I4210164364"]}],"countries":["SK"],"is_corresponding":false,"raw_author_name":"Ivana Macikov","raw_affiliation_strings":["Institute of Virology, Slovak Academy of Sciences, 842 46 Bratislava, Czech and SlovakCzech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Virology, Slovak Academy of Sciences, 842 46 Bratislava, Czech and SlovakCzech Republic","institution_ids":["https://openalex.org/I207624831","https://openalex.org/I4210164364"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066817719","display_name":"Alexandra Kolcunov\u00e1","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I207624831","display_name":"Slovak Academy of Sciences","ror":"https://ror.org/03h7qq074","country_code":"SK","type":"government","lineage":["https://openalex.org/I207624831"]},{"id":"https://openalex.org/I4210164364","display_name":"Institute of Virology of the Slovak Academy of Sciences","ror":"https://ror.org/04xrjem68","country_code":"SK","type":"facility","lineage":["https://openalex.org/I207624831","https://openalex.org/I4210123996","https://openalex.org/I4210164364"]}],"countries":["SK"],"is_corresponding":false,"raw_author_name":"Alexandra Kolcunova","raw_affiliation_strings":["Institute of Virology, Slovak Academy of Sciences, 842 46 Bratislava, Czech and SlovakCzech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Virology, Slovak Academy of Sciences, 842 46 Bratislava, Czech and SlovakCzech Republic","institution_ids":["https://openalex.org/I207624831","https://openalex.org/I4210164364"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108592550","display_name":"Michal Nov\u00e1k","orcid":"https://orcid.org/0000-0003-2384-8533","observed_orcids":["https://orcid.org/0000-0003-2384-8533"]},"institutions":[{"id":"https://openalex.org/I207624831","display_name":"Slovak Academy of Sciences","ror":"https://ror.org/03h7qq074","country_code":"SK","type":"government","lineage":["https://openalex.org/I207624831"]},{"id":"https://openalex.org/I4210164364","display_name":"Institute of Virology of the Slovak Academy of Sciences","ror":"https://ror.org/04xrjem68","country_code":"SK","type":"facility","lineage":["https://openalex.org/I207624831","https://openalex.org/I4210123996","https://openalex.org/I4210164364"]}],"countries":["SK"],"is_corresponding":false,"raw_author_name":"Michal Novak","raw_affiliation_strings":["Institute of Virology, Slovak Academy of Sciences, 842 46 Bratislava, Czech and SlovakCzech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Virology, Slovak Academy of Sciences, 842 46 Bratislava, Czech and SlovakCzech Republic","institution_ids":["https://openalex.org/I207624831","https://openalex.org/I4210164364"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006798993","display_name":"Viktor Krch\u0148\u00e1k","orcid":"https://orcid.org/0000-0001-5688-4069","observed_orcids":["https://orcid.org/0000-0001-5688-4069"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Viktor Krchnak","raw_affiliation_strings":["Leciva-Pharmaceutical Works, Prague, Czech and SlovakCzech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Leciva-Pharmaceutical Works, Prague, Czech and SlovakCzech Republic","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3340,"currency":"USD","value_usd":3340},"apc_paid":null,"fwci":1.7366,"has_fulltext":false,"cited_by_count":37,"citation_normalized_percentile":{"value":0.85212766,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"28","issue":"11","first_page":"1289","last_page":"1297"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11668","display_name":"interferon and immune responses","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11668","display_name":"interferon and immune responses","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11503","display_name":"Cytokine Signaling Pathways and Interactions","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/immunodominant-epitopes","display_name":"immunodominant epitopes","score":0.8569999933242798},{"id":"https://openalex.org/keywords/monoclonal-antibodies","display_name":"monoclonal antibodies","score":0.7009999752044678},{"id":"https://openalex.org/keywords/receptor-binding","display_name":"receptor binding","score":0.5479999780654907},{"id":"https://openalex.org/keywords/c-terminal-domain","display_name":"C-terminal domain","score":0.8009999990463257},{"id":"https://openalex.org/keywords/n-terminal-domain","display_name":"N-terminal domain","score":0.9819999933242798},{"id":"https://openalex.org/keywords/antiviral-activity","display_name":"antiviral activity","score":0.7630000114440918},{"id":"https://openalex.org/keywords/antiproliferative-activity","display_name":"antiproliferative activity","score":0.9879999756813049},{"id":"https://openalex.org/keywords/structure-function-relationship","display_name":"structure-function relationship","score":0.515999972820282}],"concepts":[{"id":"https://openalex.org/C64943373","wikidata":"https://www.wikidata.org/wiki/Q2651003","display_name":"Alpha (finance)","level":4,"score":0.6418365836143494},{"id":"https://openalex.org/C2909179924","wikidata":"https://www.wikidata.org/wiki/Q6046488","display_name":"Alpha interferon","level":3,"score":0.5416948795318604},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.40385520458221436},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.40356892347335815},{"id":"https://openalex.org/C2776178377","wikidata":"https://www.wikidata.org/wiki/Q188269","display_name":"Interferon","level":2,"score":0.3357650637626648},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.28724369406700134},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2839983403682709},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.18559002876281738},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.047528624534606934},{"id":"https://openalex.org/C171606756","wikidata":"https://www.wikidata.org/wiki/Q506132","display_name":"Psychometrics","level":2,"score":0.0},{"id":"https://openalex.org/C49453240","wikidata":"https://www.wikidata.org/wiki/Q1592163","display_name":"Construct validity","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000918","descriptor_name":"Antibody Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000939","descriptor_name":"Epitopes","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D001667","descriptor_name":"Binding, Competitive","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002455","descriptor_name":"Cell Division","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D003429","descriptor_name":"Cross Reactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004797","descriptor_name":"Enzyme-Linked Immunosorbent Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006825","descriptor_name":"Hybridomas","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007370","descriptor_name":"Interferon Type I","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010449","descriptor_name":"Peptide Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011863","descriptor_name":"Radioimmunoassay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0161-5890(91)90016-d","doi":"https://doi.org/10.1016/0161-5890(91)90016-d","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0161-5890(91)90016-d","pdf_url":null,"source":{"id":"https://openalex.org/S92126311","display_name":"Molecular Immunology","issn_l":"0161-5890","issn":["0161-5890","1872-9142"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Immunology","raw_type":"journal-article"},{"id":"pmid:1720506","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1720506","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular immunology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.4000000059604645,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W978779031","https://openalex.org/W1505277495","https://openalex.org/W1523048906","https://openalex.org/W1974408066","https://openalex.org/W1997868973","https://openalex.org/W2008060405","https://openalex.org/W2008854654","https://openalex.org/W2016627629","https://openalex.org/W2018315469","https://openalex.org/W2021889568","https://openalex.org/W2026413275","https://openalex.org/W2028264507","https://openalex.org/W2035893045","https://openalex.org/W2053418558","https://openalex.org/W2081217040","https://openalex.org/W2091468986","https://openalex.org/W2101323431","https://openalex.org/W2113530505","https://openalex.org/W2195861155","https://openalex.org/W2414779882","https://openalex.org/W2416470169","https://openalex.org/W2417037829"],"related_works":["https://openalex.org/W1987371150","https://openalex.org/W2101323431","https://openalex.org/W1969509676","https://openalex.org/W1980156005","https://openalex.org/W1970703898","https://openalex.org/W2133667234","https://openalex.org/W4313308272","https://openalex.org/W2026413275","https://openalex.org/W1973796638","https://openalex.org/W2157679799"],"abstract_inverted_index":null,"counts_by_year":[{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}