{"id":"https://openalex.org/W2015089109","doi":"https://doi.org/10.4061/2011/198430","title":"Methionine-35 of A \u03b2 (1\u201342): Importance for Oxidative Stress in Alzheimer Disease","display_name":"Methionine-35 of A \u03b2 (1\u201342): Importance for Oxidative Stress in Alzheimer Disease","publication_year":2011,"publication_date":"2011-06-04","ids":{"openalex":"https://openalex.org/W2015089109","doi":"https://doi.org/10.4061/2011/198430","mag":"2015089109","pmid":"https://pubmed.ncbi.nlm.nih.gov/22312456","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3268025"},"language":"en","primary_location":{"id":"doi:10.4061/2011/198430","doi":"https://doi.org/10.4061/2011/198430","is_oa":true,"landing_page_url":"https://doi.org/10.4061/2011/198430","pdf_url":"https://downloads.hindawi.com/archive/2011/198430.pdf","source":{"id":"https://openalex.org/S32912600","display_name":"Journal of Amino Acids","issn_l":"2090-0104","issn":["2090-0104","2090-0112"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-40"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Amino Acids","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://downloads.hindawi.com/archive/2011/198430.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008788895","display_name":"David Allan Butterfield","orcid":"https://orcid.org/0000-0003-3254-5286","observed_orcids":["https://orcid.org/0000-0003-3254-5286"]},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"D. Allan Butterfield","raw_affiliation_strings":["Center of Membrane Sciences, University of Kentucky, Lexington, KY 40506-0055, USA","Department of Chemistry, University of Kentucky, Lexington, KY 40506-0055, USA","Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40506-0055, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Membrane Sciences, University of Kentucky, Lexington, KY 40506-0055, USA","institution_ids":["https://openalex.org/I143302722"]},{"raw_affiliation_string":"Department of Chemistry, University of Kentucky, Lexington, KY 40506-0055, USA","institution_ids":["https://openalex.org/I143302722"]},{"raw_affiliation_string":"Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40506-0055, USA","institution_ids":["https://openalex.org/I143302722"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111913281","display_name":"Rukhsana Sultana A","orcid":"https://orcid.org/0000-0002-7569-3564","observed_orcids":["https://orcid.org/0000-0002-7569-3564"]},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rukhsana Sultana","raw_affiliation_strings":["Center of Membrane Sciences, University of Kentucky, Lexington, KY 40506-0055, USA","Department of Chemistry, University of Kentucky, Lexington, KY 40506-0055, USA","Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40506-0055, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Membrane Sciences, University of Kentucky, Lexington, KY 40506-0055, USA","institution_ids":["https://openalex.org/I143302722"]},{"raw_affiliation_string":"Department of Chemistry, University of Kentucky, Lexington, KY 40506-0055, USA","institution_ids":["https://openalex.org/I143302722"]},{"raw_affiliation_string":"Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40506-0055, USA","institution_ids":["https://openalex.org/I143302722"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5008788895"],"corresponding_institution_ids":["https://openalex.org/I143302722"],"apc_list":null,"apc_paid":null,"fwci":3.341,"has_fulltext":true,"cited_by_count":127,"citation_normalized_percentile":{"value":0.92746896,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"2011","issue":null,"first_page":"1","last_page":"10"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.9660000205039978},{"id":"https://openalex.org/keywords/amyloid-beta-peptide-1-42","display_name":"amyloid beta peptide 1-42","score":0.7990000247955322},{"id":"https://openalex.org/keywords/35s-methionine","display_name":"35S-methionine","score":0.9509999752044678},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.9909999966621399},{"id":"https://openalex.org/keywords/mild-cognitive-impairment","display_name":"mild cognitive impairment","score":0.9049999713897705},{"id":"https://openalex.org/keywords/amyloid-plaques","display_name":"amyloid plaques","score":0.8149999976158142},{"id":"https://openalex.org/keywords/neurofibrillary-tangles","display_name":"neurofibrillary tangles","score":0.8899999856948853},{"id":"https://openalex.org/keywords/synapse-loss","display_name":"synaptic loss","score":0.8230000138282776},{"id":"https://openalex.org/keywords/protein-oxidation","display_name":"protein oxidation","score":0.7620000243186951},{"id":"https://openalex.org/keywords/lipid-peroxidation","display_name":"lipid peroxidation","score":0.9750000238418579},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.9879999756813049},{"id":"https://openalex.org/keywords/neurotoxicity","display_name":"neurotoxicity","score":0.777999997138977}],"concepts":[{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.8828538656234741},{"id":"https://openalex.org/C68026918","wikidata":"https://www.wikidata.org/wiki/Q1970256","display_name":"Senile plaques","level":4,"score":0.7668155431747437},{"id":"https://openalex.org/C2780829032","wikidata":"https://www.wikidata.org/wiki/Q898539","display_name":"Lipid peroxidation","level":3,"score":0.5992746949195862},{"id":"https://openalex.org/C2780912031","wikidata":"https://www.wikidata.org/wiki/Q180341","display_name":"Methionine","level":3,"score":0.5438187718391418},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5402550101280212},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.525402843952179},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.49904513359069824},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.49093011021614075},{"id":"https://openalex.org/C48349386","wikidata":"https://www.wikidata.org/wiki/Q424361","display_name":"Reactive oxygen species","level":2,"score":0.4906662702560425},{"id":"https://openalex.org/C2984915365","wikidata":"https://www.wikidata.org/wiki/Q5141203","display_name":"Cognitive impairment","level":3,"score":0.4781121611595154},{"id":"https://openalex.org/C57600042","wikidata":"https://www.wikidata.org/wiki/Q227564","display_name":"Oxidative phosphorylation","level":2,"score":0.46263283491134644},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.4346272051334381},{"id":"https://openalex.org/C2777633098","wikidata":"https://www.wikidata.org/wiki/Q2736051","display_name":"Amyloid (mycology)","level":2,"score":0.4249870777130127},{"id":"https://openalex.org/C502032728","wikidata":"https://www.wikidata.org/wiki/Q11081","display_name":"Alzheimer's disease","level":3,"score":0.415641725063324},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.35437285900115967},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3392837643623352},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.29075074195861816},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2402147352695465},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.08062401413917542},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.07261732220649719}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.4061/2011/198430","doi":"https://doi.org/10.4061/2011/198430","is_oa":true,"landing_page_url":"https://doi.org/10.4061/2011/198430","pdf_url":"https://downloads.hindawi.com/archive/2011/198430.pdf","source":{"id":"https://openalex.org/S32912600","display_name":"Journal of Amino Acids","issn_l":"2090-0104","issn":["2090-0104","2090-0112"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-40"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Amino Acids","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2280261","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3268025","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3268025","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3268025","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Amino Acids","raw_type":"Text"},{"id":"pmid:22312456","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22312456","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of amino acids","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.815.1076","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.815.1076","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/19/ac/JAA2011-198430.PMC3268025.pdf","raw_type":"text"},{"id":"pmh:oai:uknowledge.uky.edu:chemistry_facpub-1018","doi":null,"is_oa":true,"landing_page_url":"https://uknowledge.uky.edu/chemistry_facpub/19","pdf_url":null,"source":{"id":"https://openalex.org/S4306402623","display_name":"UKnowledge (University of Kentucky)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I143302722","host_organization_name":"University of Kentucky","host_organization_lineage":["https://openalex.org/I143302722"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Chemistry Faculty Publications","raw_type":"text"}],"best_oa_location":{"id":"doi:10.4061/2011/198430","doi":"https://doi.org/10.4061/2011/198430","is_oa":true,"landing_page_url":"https://doi.org/10.4061/2011/198430","pdf_url":"https://downloads.hindawi.com/archive/2011/198430.pdf","source":{"id":"https://openalex.org/S32912600","display_name":"Journal of Amino Acids","issn_l":"2090-0104","issn":["2090-0104","2090-0112"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-40"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Amino Acids","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G255211753","display_name":"Beta Amyloid and Oxidative Stress in Alzheimer's Disease","funder_award_id":"P01AG005119","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G9000297989","display_name":null,"funder_award_id":"AG05119","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2015089109.pdf","grobid_xml":"https://content.openalex.org/works/W2015089109.grobid-xml"},"referenced_works_count":95,"referenced_works":["https://openalex.org/W1504283291","https://openalex.org/W1529534608","https://openalex.org/W1574724477","https://openalex.org/W1605850305","https://openalex.org/W1662308449","https://openalex.org/W1712587667","https://openalex.org/W1838272947","https://openalex.org/W1887703308","https://openalex.org/W1965310787","https://openalex.org/W1970259736","https://openalex.org/W1978308357","https://openalex.org/W1981545549","https://openalex.org/W1984172703","https://openalex.org/W1986384924","https://openalex.org/W1987476077","https://openalex.org/W1989972829","https://openalex.org/W1990159667","https://openalex.org/W1990465549","https://openalex.org/W1991634503","https://openalex.org/W1992482429","https://openalex.org/W1996579240","https://openalex.org/W2001001850","https://openalex.org/W2001591118","https://openalex.org/W2006126892","https://openalex.org/W2008032082","https://openalex.org/W2008613466","https://openalex.org/W2008649582","https://openalex.org/W2010575628","https://openalex.org/W2011635175","https://openalex.org/W2012144638","https://openalex.org/W2020981217","https://openalex.org/W2021757608","https://openalex.org/W2022887646","https://openalex.org/W2023786276","https://openalex.org/W2029115752","https://openalex.org/W2033825402","https://openalex.org/W2033900283","https://openalex.org/W2037231427","https://openalex.org/W2038421461","https://openalex.org/W2043733841","https://openalex.org/W2045855955","https://openalex.org/W2046998110","https://openalex.org/W2049192526","https://openalex.org/W2049262684","https://openalex.org/W2051516838","https://openalex.org/W2052120254","https://openalex.org/W2053611228","https://openalex.org/W2054442047","https://openalex.org/W2056293127","https://openalex.org/W2057742004","https://openalex.org/W2059499535","https://openalex.org/W2063321102","https://openalex.org/W2066434151","https://openalex.org/W2067814874","https://openalex.org/W2068290140","https://openalex.org/W2070623737","https://openalex.org/W2076184221","https://openalex.org/W2077271414","https://openalex.org/W2080162788","https://openalex.org/W2081412929","https://openalex.org/W2086249546","https://openalex.org/W2088088066","https://openalex.org/W2091665009","https://openalex.org/W2094509354","https://openalex.org/W2102042818","https://openalex.org/W2103024032","https://openalex.org/W2105939406","https://openalex.org/W2106406927","https://openalex.org/W2107900038","https://openalex.org/W2109886223","https://openalex.org/W2110330803","https://openalex.org/W2114139136","https://openalex.org/W2115978010","https://openalex.org/W2118206405","https://openalex.org/W2120940067","https://openalex.org/W2123619340","https://openalex.org/W2124634545","https://openalex.org/W2124955411","https://openalex.org/W2128337365","https://openalex.org/W2131181742","https://openalex.org/W2131416756","https://openalex.org/W2133324295","https://openalex.org/W2135242771","https://openalex.org/W2136637275","https://openalex.org/W2144857111","https://openalex.org/W2147699521","https://openalex.org/W2152119060","https://openalex.org/W2161844942","https://openalex.org/W2164868723","https://openalex.org/W2168033104","https://openalex.org/W2169152986","https://openalex.org/W2169393803","https://openalex.org/W2170111492","https://openalex.org/W2184190506","https://openalex.org/W2205957035"],"related_works":["https://openalex.org/W7096413247","https://openalex.org/W2146216114","https://openalex.org/W2105939406","https://openalex.org/W7095295261","https://openalex.org/W7097664119","https://openalex.org/W2113988778","https://openalex.org/W2153767421","https://openalex.org/W2013205631","https://openalex.org/W7098958356","https://openalex.org/W2033825402"],"abstract_inverted_index":{"Alzheimer":[0],"disease":[1,11,179],"(AD)":[2],"is":[3,12,32,39,141],"an":[4,142],"age-related":[5],"progressive":[6],"neurodegenerative":[7],"disorder.":[8],"This":[9],"devastating":[10],"characterized":[13],"by":[14],"the":[15,33,77,90,97,146,165,168],"presence":[16],"of":[17,26,36,45,61,71,99,107,139,162,167,172],"senile":[18],"plaques":[19],"(SP),":[20],"neurofibrillary":[21],"tangles":[22],"(NFTs),":[23],"and":[24,38,49,73,75,92,96,110,126,131,183],"loss":[25,98],"synapses.":[27],"Amyloid":[28],"beta-peptide":[29],"1-42":[30],"(A\u03b2(1-42))":[31],"main":[34],"component":[35],"SP":[37],"pivotal":[40],"to":[41,84,145],"AD":[42,48,72,93,182],"pathogenesis.":[43],"Brain":[44],"subjects":[46],"with":[47,150],"arguably":[50],"its":[51],"earliest":[52],"manifestation,":[53],"mild":[54],"cognitive":[55],"impairment":[56],"(MCI),":[57],"demonstrate":[58],"increased":[59],"levels":[60],"oxidative":[62,81,86,147],"stress":[63,82,87,148],"markers.":[64],"Our":[65],"laboratory":[66],"combined":[67],"these":[68],"two":[69],"aspects":[70],"MCI":[74,91],"proposed":[76],"A\u03b2(1-42)-associated":[78],"free":[79],"radical":[80],"hypothesis":[83],"explain":[85],"under":[88],"which":[89],"brain":[94],"exist":[95],"synapses":[100],"in":[101,108,111,129,176,181],"both":[102],"disorders.":[103],"A":[104],"large":[105],"number":[106],"vitro":[109],"vivo":[112],"studies":[113,159],"showed":[114],"that":[115],"A\u03b2":[116],"causes":[117],"protein":[118],"oxidation,":[119],"lipid":[120],"peroxidation,":[121],"reactive":[122],"oxygen":[123],"species":[124],"formation,":[125],"cell":[127],"death":[128],"neuronal":[130],"synaptosomal":[132],"systems.":[133],"Methionine":[134],"located":[135],"at":[136],"residue":[137,171],"35":[138],"A\u03b2(1-42)":[140,173],"important":[143],"contributor":[144],"associated":[149],"this":[151,155],"neurotoxic":[152],"peptide.":[153],"In":[154],"paper,":[156],"we":[157],"summarize":[158],"involving":[160],"Met-35":[161],"A\u03b2(1-42).":[163],"Understanding":[164],"role":[166],"single":[169],"methionine":[170],"may":[174],"help":[175],"understanding":[177],"underlying":[178],"mechanisms":[180],"MCI.":[184]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":26},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":8},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":10}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}
