{"id":"https://openalex.org/W2015046207","doi":"https://doi.org/10.1159/000362958","title":"The Predominant Pathway of Apoptosis in THP-1 Macrophage-Derived Foam Cells Induced by 5-Aminolevulinic Acid-Mediated Sonodynamic Therapy is the Mitochondria-Caspase Pathway Despite the Participation of Endoplasmic Reticulum Stress","display_name":"The Predominant Pathway of Apoptosis in THP-1 Macrophage-Derived Foam Cells Induced by 5-Aminolevulinic Acid-Mediated Sonodynamic Therapy is the Mitochondria-Caspase Pathway Despite the Participation of Endoplasmic Reticulum Stress","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W2015046207","doi":"https://doi.org/10.1159/000362958","mag":"2015046207","pmid":"https://pubmed.ncbi.nlm.nih.gov/24923653"},"language":"en","primary_location":{"id":"doi:10.1159/000362958","doi":"https://doi.org/10.1159/000362958","is_oa":true,"landing_page_url":"https://doi.org/10.1159/000362958","pdf_url":"https://www.karger.com/Article/Pdf/362958","source":{"id":"https://openalex.org/S161399637","display_name":"Cellular Physiology and Biochemistry","issn_l":"1015-8987","issn":["1015-8987","1421-9778"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cellular Physiology and Biochemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.karger.com/Article/Pdf/362958","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101106471","display_name":"Huan Wang","orcid":"https://orcid.org/0000-0003-2803-3317","observed_orcids":["https://orcid.org/0000-0003-2803-3317"]},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]},{"id":"https://openalex.org/I4210156501","display_name":"First Affiliated Hospital of Harbin Medical University","ror":"https://ror.org/05vy2sc54","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210156501"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huan Wang","raw_affiliation_strings":["Division of Cardiology, the First Affiliated Hospital, Cardiovascular Institute, Harbin Medical University, Harbin, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, the First Affiliated Hospital, Cardiovascular Institute, Harbin Medical University, Harbin, China","institution_ids":["https://openalex.org/I156144747","https://openalex.org/I4210156501"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100397410","display_name":"Yang Yang","orcid":"https://orcid.org/0000-0001-6788-2843","observed_orcids":["https://orcid.org/0000-0001-6788-2843"]},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]},{"id":"https://openalex.org/I4210156501","display_name":"First Affiliated Hospital of Harbin Medical University","ror":"https://ror.org/05vy2sc54","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210156501"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yang Yang","raw_affiliation_strings":["Division of Cardiology , the First Affiliated Hospital , Cardiovascular Institute , Harbin Medical University ,","Harbin Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology , the First Affiliated Hospital , Cardiovascular Institute , Harbin Medical University ,","institution_ids":["https://openalex.org/I156144747","https://openalex.org/I4210156501"]},{"raw_affiliation_string":"Harbin Medical University","institution_ids":["https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100406209","display_name":"Haibo Chen","orcid":"https://orcid.org/0000-0001-6553-3957","observed_orcids":["https://orcid.org/0000-0001-6553-3957","https://orcid.org/0000-0002-2602-9915"]},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]},{"id":"https://openalex.org/I4210156501","display_name":"First Affiliated Hospital of Harbin Medical University","ror":"https://ror.org/05vy2sc54","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210156501"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haibo Chen","raw_affiliation_strings":["Division of Cardiology , the First Affiliated Hospital , Cardiovascular Institute , Harbin Medical University ,","Harbin Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology , the First Affiliated Hospital , Cardiovascular Institute , Harbin Medical University ,","institution_ids":["https://openalex.org/I156144747","https://openalex.org/I4210156501"]},{"raw_affiliation_string":"Harbin Medical University","institution_ids":["https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018256911","display_name":"Juhua Dan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1327237609","display_name":"Ministry of Education of the People's Republic of China","ror":"https://ror.org/01mv9t934","country_code":"CN","type":"government","lineage":["https://openalex.org/I1327237609","https://openalex.org/I4210127390"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Juhua Dan","raw_affiliation_strings":["Department of Pathophysiology , the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China , Key Laboratory of Cardiovascular Research , Ministry of Education ,","Ministry of Education, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathophysiology , the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China , Key Laboratory of Cardiovascular Research , Ministry of Education ,","institution_ids":[]},{"raw_affiliation_string":"Ministry of Education, China","institution_ids":["https://openalex.org/I1327237609"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101545345","display_name":"Jiali Cheng","orcid":"https://orcid.org/0000-0003-3210-2522","observed_orcids":["https://orcid.org/0000-0003-3210-2522","https://orcid.org/0009-0003-0560-2879"]},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]},{"id":"https://openalex.org/I4210156501","display_name":"First Affiliated Hospital of Harbin Medical University","ror":"https://ror.org/05vy2sc54","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210156501"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiali Cheng","raw_affiliation_strings":["Division of Cardiology , the First Affiliated Hospital , Cardiovascular Institute , Harbin Medical University ,","Harbin Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology , the First Affiliated Hospital , Cardiovascular Institute , Harbin Medical University ,","institution_ids":["https://openalex.org/I156144747","https://openalex.org/I4210156501"]},{"raw_affiliation_string":"Harbin Medical University","institution_ids":["https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103119246","display_name":"Shuyuan Guo","orcid":"https://orcid.org/0000-0002-7363-4974","observed_orcids":["https://orcid.org/0000-0002-7363-4974"]},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]},{"id":"https://openalex.org/I4210156501","display_name":"First Affiliated Hospital of Harbin Medical University","ror":"https://ror.org/05vy2sc54","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210156501"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shuyuan Guo","raw_affiliation_strings":["Division of Cardiology , the First Affiliated Hospital , Cardiovascular Institute , Harbin Medical University ,","Harbin Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology , the First Affiliated Hospital , Cardiovascular Institute , Harbin Medical University ,","institution_ids":["https://openalex.org/I156144747","https://openalex.org/I4210156501"]},{"raw_affiliation_string":"Harbin Medical University","institution_ids":["https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110368992","display_name":"Xin Sun","orcid":"https://orcid.org/0009-0007-4776-2853","observed_orcids":["https://orcid.org/0009-0007-4776-2853"]},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]},{"id":"https://openalex.org/I4210156501","display_name":"First Affiliated Hospital of Harbin Medical University","ror":"https://ror.org/05vy2sc54","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210156501"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xin Sun","raw_affiliation_strings":["Division of Cardiology , the First Affiliated Hospital , Cardiovascular Institute , Harbin Medical University ,","Harbin Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology , the First Affiliated Hospital , Cardiovascular Institute , Harbin Medical University ,","institution_ids":["https://openalex.org/I156144747","https://openalex.org/I4210156501"]},{"raw_affiliation_string":"Harbin Medical University","institution_ids":["https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100391961","display_name":"Wei Wang","orcid":"https://orcid.org/0000-0002-4104-4646","observed_orcids":["https://orcid.org/0000-0002-4104-4646"]},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]},{"id":"https://openalex.org/I4210156501","display_name":"First Affiliated Hospital of Harbin Medical University","ror":"https://ror.org/05vy2sc54","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210156501"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Wang","raw_affiliation_strings":["Division of Cardiology , the First Affiliated Hospital , Cardiovascular Institute , Harbin Medical University ,","Harbin Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology , the First Affiliated Hospital , Cardiovascular Institute , Harbin Medical University ,","institution_ids":["https://openalex.org/I156144747","https://openalex.org/I4210156501"]},{"raw_affiliation_string":"Harbin Medical University","institution_ids":["https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052153793","display_name":"Yiwei Ai","orcid":"https://orcid.org/0000-0002-3359-5464","observed_orcids":["https://orcid.org/0000-0002-3359-5464"]},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]},{"id":"https://openalex.org/I4210156501","display_name":"First Affiliated Hospital of Harbin Medical University","ror":"https://ror.org/05vy2sc54","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210156501"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yiwei Ai","raw_affiliation_strings":["Division of Cardiology , the First Affiliated Hospital , Cardiovascular Institute , Harbin Medical University ,","Harbin Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology , the First Affiliated Hospital , Cardiovascular Institute , Harbin Medical University ,","institution_ids":["https://openalex.org/I156144747","https://openalex.org/I4210156501"]},{"raw_affiliation_string":"Harbin Medical University","institution_ids":["https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Shuchang Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]},{"id":"https://openalex.org/I4210156501","display_name":"First Affiliated Hospital of Harbin Medical University","ror":"https://ror.org/05vy2sc54","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210156501"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shuchang Li","raw_affiliation_strings":["Division of Cardiology , the First Affiliated Hospital , Cardiovascular Institute , Harbin Medical University ,","Harbin Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology , the First Affiliated Hospital , Cardiovascular Institute , Harbin Medical University ,","institution_ids":["https://openalex.org/I156144747","https://openalex.org/I4210156501"]},{"raw_affiliation_string":"Harbin Medical University","institution_ids":["https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100701702","display_name":"Zhixin Li","orcid":"https://orcid.org/0009-0001-0797-0048","observed_orcids":["https://orcid.org/0009-0001-0797-0048","https://orcid.org/0009-0007-6200-441X"]},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]},{"id":"https://openalex.org/I4210156501","display_name":"First Affiliated Hospital of Harbin Medical University","ror":"https://ror.org/05vy2sc54","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210156501"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhixin Li","raw_affiliation_strings":["Division of Cardiology , the First Affiliated Hospital , Cardiovascular Institute , Harbin Medical University ,","Harbin Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology , the First Affiliated Hospital , Cardiovascular Institute , Harbin Medical University ,","institution_ids":["https://openalex.org/I156144747","https://openalex.org/I4210156501"]},{"raw_affiliation_string":"Harbin Medical University","institution_ids":["https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110190629","display_name":"Li Hua Peng","orcid":"https://orcid.org/0009-0000-5017-1690","observed_orcids":["https://orcid.org/0009-0000-5017-1690"]},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]},{"id":"https://openalex.org/I4210156501","display_name":"First Affiliated Hospital of Harbin Medical University","ror":"https://ror.org/05vy2sc54","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210156501"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Li Peng","raw_affiliation_strings":["Division of Cardiology , the First Affiliated Hospital , Cardiovascular Institute , Harbin Medical University ,","Harbin Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology , the First Affiliated Hospital , Cardiovascular Institute , Harbin Medical University ,","institution_ids":["https://openalex.org/I156144747","https://openalex.org/I4210156501"]},{"raw_affiliation_string":"Harbin Medical University","institution_ids":["https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017894990","display_name":"Zhen Tian","orcid":"https://orcid.org/0000-0001-9044-637X","observed_orcids":["https://orcid.org/0000-0001-9044-637X"]},"institutions":[{"id":"https://openalex.org/I1327237609","display_name":"Ministry of Education of the People's Republic of China","ror":"https://ror.org/01mv9t934","country_code":"CN","type":"government","lineage":["https://openalex.org/I1327237609","https://openalex.org/I4210127390"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhen Tian","raw_affiliation_strings":["Department of Pathophysiology , the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China , Key Laboratory of Cardiovascular Research , Ministry of Education ,","Ministry of Education, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathophysiology , the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China , Key Laboratory of Cardiovascular Research , Ministry of Education ,","institution_ids":[]},{"raw_affiliation_string":"Ministry of Education, China","institution_ids":["https://openalex.org/I1327237609"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100662124","display_name":"Liming M Yang","orcid":"https://orcid.org/0000-0002-0390-8845","observed_orcids":["https://orcid.org/0000-0002-0390-8845"]},"institutions":[{"id":"https://openalex.org/I1327237609","display_name":"Ministry of Education of the People's Republic of China","ror":"https://ror.org/01mv9t934","country_code":"CN","type":"government","lineage":["https://openalex.org/I1327237609","https://openalex.org/I4210127390"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liming Yang","raw_affiliation_strings":["Department of Pathophysiology , the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China , Key Laboratory of Cardiovascular Research , Ministry of Education ,","Ministry of Education, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathophysiology , the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China , Key Laboratory of Cardiovascular Research , Ministry of Education ,","institution_ids":[]},{"raw_affiliation_string":"Ministry of Education, China","institution_ids":["https://openalex.org/I1327237609"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5115587877","display_name":"Jichao Wu","orcid":"https://orcid.org/0009-0006-0613-7085","observed_orcids":["https://orcid.org/0009-0006-0613-7085"]},"institutions":[{"id":"https://openalex.org/I1327237609","display_name":"Ministry of Education of the People's Republic of China","ror":"https://ror.org/01mv9t934","country_code":"CN","type":"government","lineage":["https://openalex.org/I1327237609","https://openalex.org/I4210127390"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jichao Wu","raw_affiliation_strings":["Department of Pathophysiology , the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China , Key Laboratory of Cardiovascular Research , Ministry of Education ,","Ministry of Education, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathophysiology , the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China , Key Laboratory of Cardiovascular Research , Ministry of Education ,","institution_ids":[]},{"raw_affiliation_string":"Ministry of Education, China","institution_ids":["https://openalex.org/I1327237609"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Xin Zhong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1327237609","display_name":"Ministry of Education of the People's Republic of China","ror":"https://ror.org/01mv9t934","country_code":"CN","type":"government","lineage":["https://openalex.org/I1327237609","https://openalex.org/I4210127390"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xin Zhong","raw_affiliation_strings":["Department of Pathophysiology , the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China , Key Laboratory of Cardiovascular Research , Ministry of Education ,","Ministry of Education, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathophysiology , the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China , Key Laboratory of Cardiovascular Research , Ministry of Education ,","institution_ids":[]},{"raw_affiliation_string":"Ministry of Education, China","institution_ids":["https://openalex.org/I1327237609"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033388802","display_name":"Qi Zhou","orcid":"https://orcid.org/0000-0002-6179-6474","observed_orcids":["https://orcid.org/0000-0002-6179-6474"]},"institutions":[{"id":"https://openalex.org/I204983213","display_name":"Harbin Institute of Technology","ror":"https://ror.org/01yqg2h08","country_code":"CN","type":"education","lineage":["https://openalex.org/I204983213"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qi Zhou","raw_affiliation_strings":["Laboratory of Photo- and Sono-theranostic Technologies and Condensed Matter Science and Technology Institute , Harbin Institute of Technology , Harbin , China,","Harbin Institute of Technology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Photo- and Sono-theranostic Technologies and Condensed Matter Science and Technology Institute , Harbin Institute of Technology , Harbin , China,","institution_ids":["https://openalex.org/I204983213"]},{"raw_affiliation_string":"Harbin Institute of Technology","institution_ids":["https://openalex.org/I204983213"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100395944","display_name":"Peng Wang","orcid":"https://orcid.org/0000-0001-8997-6525","observed_orcids":["https://orcid.org/0000-0001-8997-6525"]},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]},{"id":"https://openalex.org/I204983213","display_name":"Harbin Institute of Technology","ror":"https://ror.org/01yqg2h08","country_code":"CN","type":"education","lineage":["https://openalex.org/I204983213"]},{"id":"https://openalex.org/I4210156501","display_name":"First Affiliated Hospital of Harbin Medical University","ror":"https://ror.org/05vy2sc54","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210156501"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Peng Wang","raw_affiliation_strings":["Division of Cardiology , the First Affiliated Hospital , Harbin Medical University , 23 Youzheng Street , Harbin 150001 , (China","Laboratory of Photo- and Sono-theranostic Technologies and Condensed Matter Science and Technology Institute , Harbin Institute of Technology , Harbin , China,","Harbin Institute of Technology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology , the First Affiliated Hospital , Harbin Medical University , 23 Youzheng Street , Harbin 150001 , (China","institution_ids":["https://openalex.org/I156144747","https://openalex.org/I4210156501"]},{"raw_affiliation_string":"Laboratory of Photo- and Sono-theranostic Technologies and Condensed Matter Science and Technology Institute , Harbin Institute of Technology , Harbin , China,","institution_ids":["https://openalex.org/I204983213"]},{"raw_affiliation_string":"Harbin Institute of Technology","institution_ids":["https://openalex.org/I204983213"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100363361","display_name":"Zhiguo Zhang","orcid":"https://orcid.org/0000-0003-3982-9900","observed_orcids":["https://orcid.org/0000-0003-3982-9900"]},"institutions":[{"id":"https://openalex.org/I204983213","display_name":"Harbin Institute of Technology","ror":"https://ror.org/01yqg2h08","country_code":"CN","type":"education","lineage":["https://openalex.org/I204983213"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhiguo Zhang","raw_affiliation_strings":["Laboratory of Photo- and Sono-theranostic Technologies and Condensed Matter Science and Technology Institute , Harbin Institute of Technology , Harbin , China,","Harbin Institute of Technology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Photo- and Sono-theranostic Technologies and Condensed Matter Science and Technology Institute , Harbin Institute of Technology , Harbin , China,","institution_ids":["https://openalex.org/I204983213"]},{"raw_affiliation_string":"Harbin Institute of Technology","institution_ids":["https://openalex.org/I204983213"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101508915","display_name":"Wenwu Cao","orcid":"https://orcid.org/0000-0002-2447-1486","observed_orcids":["https://orcid.org/0000-0002-2447-1486"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]},{"id":"https://openalex.org/I204983213","display_name":"Harbin Institute of Technology","ror":"https://ror.org/01yqg2h08","country_code":"CN","type":"education","lineage":["https://openalex.org/I204983213"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Wenwu Cao","raw_affiliation_strings":["Laboratory of Photo- and Sono-theranostic Technologies and Condensed Matter Science and Technology Institute , Harbin Institute of Technology , Harbin , China,","Materials Research Institute , The Pennsylvania State University , University Park , Pennsylvania , USA","Mathematics"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Photo- and Sono-theranostic Technologies and Condensed Matter Science and Technology Institute , Harbin Institute of Technology , Harbin , China,","institution_ids":["https://openalex.org/I204983213"]},{"raw_affiliation_string":"Materials Research Institute , The Pennsylvania State University , University Park , Pennsylvania , USA","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"Mathematics","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100387922","display_name":"Ye Tian","orcid":"https://orcid.org/0000-0003-3726-7270","observed_orcids":["https://orcid.org/0000-0003-3726-7270"]},"institutions":[{"id":"https://openalex.org/I1327237609","display_name":"Ministry of Education of the People's Republic of China","ror":"https://ror.org/01mv9t934","country_code":"CN","type":"government","lineage":["https://openalex.org/I1327237609","https://openalex.org/I4210127390"]},{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]},{"id":"https://openalex.org/I4210156501","display_name":"First Affiliated Hospital of Harbin Medical University","ror":"https://ror.org/05vy2sc54","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210156501"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ye Tian","raw_affiliation_strings":["Department of Pathophysiology , the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China , Key Laboratory of Cardiovascular Research , Ministry of Education ,","Division of Cardiology , the First Affiliated Hospital , Cardiovascular Institute , Harbin Medical University ,","Harbin Medical University","Ministry of Education, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathophysiology , the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China , Key Laboratory of Cardiovascular Research , Ministry of Education ,","institution_ids":[]},{"raw_affiliation_string":"Division of Cardiology , the First Affiliated Hospital , Cardiovascular Institute , Harbin Medical University ,","institution_ids":["https://openalex.org/I156144747","https://openalex.org/I4210156501"]},{"raw_affiliation_string":"Harbin Medical University","institution_ids":["https://openalex.org/I156144747"]},{"raw_affiliation_string":"Ministry of Education, China","institution_ids":["https://openalex.org/I1327237609"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":1785,"currency":"EUR","value_usd":1925},"apc_paid":{"value":1785,"currency":"EUR","value_usd":1925},"fwci":2.0424,"has_fulltext":true,"cited_by_count":55,"citation_normalized_percentile":{"value":0.85702536,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"33","issue":"6","first_page":"1789","last_page":"1801"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10957","display_name":"Photodynamic Therapy Research Studies","score":0.6615999937057495,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10957","display_name":"Photodynamic Therapy Research Studies","score":0.6615999937057495,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10294","display_name":"Cell death mechanisms and regulation","score":0.21359999477863312,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases","score":0.031599998474121094,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sonodynamic-therapy","display_name":"sonodynamic therapy","score":0.8259999752044678},{"id":"https://openalex.org/keywords/5-aminolevulinic-acid","display_name":"5-aminolevulinic acid","score":0.9980000257492065},{"id":"https://openalex.org/keywords/foam-cells","display_name":"foam cells","score":0.6759999990463257},{"id":"https://openalex.org/keywords/macrophages","display_name":"macrophages","score":0.8949999809265137},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.9190000295639038},{"id":"https://openalex.org/keywords/endoplasmic-reticulum-stress","display_name":"endoplasmic reticulum stress","score":0.9959999918937683},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.8330000042915344},{"id":"https://openalex.org/keywords/mitochondrial-membrane-potential","display_name":"mitochondrial membrane potential","score":0.9459999799728394},{"id":"https://openalex.org/keywords/cytochrome-c-release","display_name":"cytochrome c release","score":0.8600000143051147},{"id":"https://openalex.org/keywords/bax","display_name":"Bax","score":0.7519999742507935},{"id":"https://openalex.org/keywords/caspase-9","display_name":"caspase-9","score":0.8360000252723694},{"id":"https://openalex.org/keywords/caspase-3","display_name":"caspase-3","score":0.9990000128746033},{"id":"https://openalex.org/keywords/chop","display_name":"CHOP","score":0.9229999780654907},{"id":"https://openalex.org/keywords/bcl-2","display_name":"Bcl-2","score":0.9259999990463257},{"id":"https://openalex.org/keywords/atherosclerosis","display_name":"atherosclerosis","score":0.7689999938011169},{"id":"https://openalex.org/keywords/n-acetylcysteine","display_name":"N-acetylcysteine","score":0.902999997138977}],"concepts":[{"id":"https://openalex.org/C2778448707","wikidata":"https://www.wikidata.org/wiki/Q7562147","display_name":"Sonodynamic therapy","level":3,"score":0.7120341062545776},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.6776884198188782},{"id":"https://openalex.org/C139447449","wikidata":"https://www.wikidata.org/wiki/Q14633900","display_name":"Unfolded protein response","level":3,"score":0.6505175828933716},{"id":"https://openalex.org/C29311851","wikidata":"https://www.wikidata.org/wiki/Q408223","display_name":"Cytochrome c","level":3,"score":0.6356057524681091},{"id":"https://openalex.org/C158617107","wikidata":"https://www.wikidata.org/wiki/Q79927","display_name":"Endoplasmic reticulum","level":2,"score":0.6306131482124329},{"id":"https://openalex.org/C28859421","wikidata":"https://www.wikidata.org/wiki/Q39572","display_name":"Mitochondrion","level":2,"score":0.6132593750953674},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5713200569152832},{"id":"https://openalex.org/C193349765","wikidata":"https://www.wikidata.org/wiki/Q2061363","display_name":"Apoptosome","level":5,"score":0.48466116189956665},{"id":"https://openalex.org/C127561419","wikidata":"https://www.wikidata.org/wiki/Q224527","display_name":"Downregulation and upregulation","level":3,"score":0.47162365913391113},{"id":"https://openalex.org/C98424977","wikidata":"https://www.wikidata.org/wiki/Q25805","display_name":"Caspase","level":4,"score":0.46017730236053467},{"id":"https://openalex.org/C2780292996","wikidata":"https://www.wikidata.org/wiki/Q18068044","display_name":"Caspase 12","level":5,"score":0.4597063660621643},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4539957642555237},{"id":"https://openalex.org/C204258353","wikidata":"https://www.wikidata.org/wiki/Q7670282","display_name":"THP1 cell line","level":3,"score":0.44535309076309204},{"id":"https://openalex.org/C163421366","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Intrinsic apoptosis","level":5,"score":0.4333465099334717},{"id":"https://openalex.org/C48349386","wikidata":"https://www.wikidata.org/wiki/Q424361","display_name":"Reactive oxygen species","level":2,"score":0.42439383268356323},{"id":"https://openalex.org/C2775998712","wikidata":"https://www.wikidata.org/wiki/Q14907714","display_name":"Caspase-9","level":5,"score":0.4112313985824585},{"id":"https://openalex.org/C88634738","wikidata":"https://www.wikidata.org/wiki/Q24769543","display_name":"Annexin","level":3,"score":0.4107888340950012},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3868858218193054},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3032498359680176},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2904784679412842},{"id":"https://openalex.org/C31573885","wikidata":"https://www.wikidata.org/wiki/Q304484","display_name":"Programmed cell death","level":3,"score":0.19883403182029724},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.11002025008201599},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000622","descriptor_name":"Aminolevulinic Acid","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D003600","descriptor_name":"Cytosol","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D003600","descriptor_name":"Cytosol","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005487","descriptor_name":"Foam Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D005487","descriptor_name":"Foam Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013010","descriptor_name":"Sonication","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D014464","descriptor_name":"Ultrasonic Therapy","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D015151","descriptor_name":"Immunoblotting","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D017382","descriptor_name":"Reactive Oxygen Species","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018613","descriptor_name":"Microscopy, Confocal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020169","descriptor_name":"Caspases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D021381","descriptor_name":"Protein Transport","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D045304","descriptor_name":"Cytochromes c","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051028","descriptor_name":"bcl-2-Associated X Protein","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D053078","descriptor_name":"Membrane Potential, Mitochondrial","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D059865","descriptor_name":"Endoplasmic Reticulum Stress","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1159/000362958","doi":"https://doi.org/10.1159/000362958","is_oa":true,"landing_page_url":"https://doi.org/10.1159/000362958","pdf_url":"https://www.karger.com/Article/Pdf/362958","source":{"id":"https://openalex.org/S161399637","display_name":"Cellular Physiology and Biochemistry","issn_l":"1015-8987","issn":["1015-8987","1421-9778"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cellular Physiology and Biochemistry","raw_type":"journal-article"},{"id":"pmid:24923653","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24923653","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:aabd1e797a4b478f8079ddf6ab0e0f4b","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/aabd1e797a4b478f8079ddf6ab0e0f4b","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cellular Physiology and Biochemistry, Vol 33, Iss 6, Pp 1789-1801 (2014)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1159/000362958","doi":"https://doi.org/10.1159/000362958","is_oa":true,"landing_page_url":"https://doi.org/10.1159/000362958","pdf_url":"https://www.karger.com/Article/Pdf/362958","source":{"id":"https://openalex.org/S161399637","display_name":"Cellular Physiology and Biochemistry","issn_l":"1015-8987","issn":["1015-8987","1421-9778"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cellular Physiology and Biochemistry","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3709152338","display_name":null,"funder_award_id":"81121003","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7631544782","display_name":null,"funder_award_id":"(81171483","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2015046207.pdf","grobid_xml":"https://content.openalex.org/works/W2015046207.grobid-xml"},"referenced_works_count":35,"referenced_works":["https://openalex.org/W18060272","https://openalex.org/W1607777232","https://openalex.org/W1909609524","https://openalex.org/W1964064254","https://openalex.org/W1970516435","https://openalex.org/W1973493114","https://openalex.org/W1974189136","https://openalex.org/W1976264665","https://openalex.org/W1985749510","https://openalex.org/W1986568749","https://openalex.org/W1991233540","https://openalex.org/W1994607100","https://openalex.org/W1996833785","https://openalex.org/W2001222190","https://openalex.org/W2001399725","https://openalex.org/W2004763954","https://openalex.org/W2014019501","https://openalex.org/W2028385125","https://openalex.org/W2029050071","https://openalex.org/W2030013026","https://openalex.org/W2041600084","https://openalex.org/W2054490551","https://openalex.org/W2069206405","https://openalex.org/W2091493364","https://openalex.org/W2106126807","https://openalex.org/W2113934014","https://openalex.org/W2114071286","https://openalex.org/W2127833553","https://openalex.org/W2145779239","https://openalex.org/W2149967205","https://openalex.org/W2159650080","https://openalex.org/W2164522756","https://openalex.org/W2167574573","https://openalex.org/W2172232070","https://openalex.org/W2183453091"],"related_works":["https://openalex.org/W2016541954","https://openalex.org/W2324223590","https://openalex.org/W2014286954","https://openalex.org/W2804802680","https://openalex.org/W2802111665","https://openalex.org/W3147923119","https://openalex.org/W2291634276","https://openalex.org/W2044448807","https://openalex.org/W2033579402","https://openalex.org/W2012986282"],"abstract_inverted_index":{"BACKGROUND:":[0],"In":[1],"advanced":[2],"atherosclerosis,":[3],"chronic":[4],"endoplasmic":[5],"reticulum":[6],"(ER)":[7],"stress":[8,204],"induces":[9],"foam":[10,20],"cells":[11,21],"apoptosis":[12,37,92,179,196],"and":[13,51,63,80,106,116,129,173],"generates":[14],"inflammatory":[15],"reactions.":[16],"METHODS:":[17],"THP-1":[18],"macrophage-derived":[19],"(FC)":[22],"were":[23,55,84,152],"incubated":[24],"with":[25,59,68,101],"1":[26],"mM":[27],"5-aminolevulinic":[28],"acid":[29],"(ALA).":[30],"After":[31,110],"ALA":[32,105],"mediated":[33],"sonodynamic":[34],"therapy":[35],"(ALA-SDT),":[36],"of":[38,66,91,93,104,122,142,148,161,197],"FC":[39,67,94,198],"was":[40,95],"assayed":[41,85],"by":[42,57,86,158,168,181,186,200],"Annexin":[43],"V-PI":[44],"staining.":[45],"Intracellular":[46],"reactive":[47],"oxygen":[48],"species":[49],"(ROS)":[50],"mitochondrial":[52,117],"membrane":[53,118],"potential":[54,119],"detected":[56],"staining":[58],"CellROX\u00ae":[60],"Green":[61],"Reagent":[62],"jc-1.":[64],"Pretreatment":[65],"N-acetylcysteine":[69],"(NAC),":[70],"Z-VAD-FMK":[71],"or":[72],"4-phenylbutyrate":[73],"(4-PBA),":[74],"mitochondria":[75,126],"apoptotic":[76],"pathway":[77,163,191],"associated":[78],"proteins":[79],"C/EBP-homologous":[81],"(CHOP)":[82],"expressions":[83],"wertern":[87],"blotting.":[88],"RESULTS:":[89],"Burst":[90],"observed":[96],"at":[97],"5-hour":[98],"after":[99,150],"ALA-SDT":[100,151,182,201],"6-hour":[102],"incubation":[103],"0.4":[107],"W/cm(2)":[108],"ultrasound.":[109],"ALA-SDT,":[111],"intracellular":[112],"ROS":[113],"level":[114],"increased":[115],"collapsed.":[120],"Translocations":[121],"cytochrome":[123],"c":[124],"from":[125,131],"into":[127,133],"cytosol":[128,132],"Bax":[130],"mitochondria,":[134],"cleaved":[135,138],"caspase":[136,139,171,174],"9,":[137],"3,":[140],"upregulation":[141],"CHOP,":[143],"as":[144,146,176,178],"well":[145,177],"downregulation":[147],"Bcl-2":[149],"detected,":[153],"which":[154],"could":[155,164,183],"be":[156,166,184],"suppressed":[157],"NAC.":[159],"Activation":[160],"mitochondria-caspase":[162,190],"not":[165],"inhibited":[167,185],"4-PBA.":[169],"Cleaved":[170],"9":[172],"3":[175],"induced":[180,199],"Z-VAD-FMK.":[187],"CONCLUSION:":[188],"The":[189],"is":[192],"predominant":[193],"in":[194],"the":[195],"though":[202],"ER":[203],"participates":[205],"in.":[206]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":9},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}