{"id":"https://openalex.org/W201492055","doi":null,"title":"Anticoagulation and atrial fibrillation. Putting the results of clinical trials into practice.","display_name":"Anticoagulation and atrial fibrillation. Putting the results of clinical trials into practice.","publication_year":1995,"publication_date":"1995-08-01","ids":{"openalex":"https://openalex.org/W201492055","mag":"201492055","pmid":"https://pubmed.ncbi.nlm.nih.gov/7571562","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1303009"},"language":"en","primary_location":{"id":"pmh:oai:europepmc.org:196441","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1303009","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1303009","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088228151","display_name":"Joyce E. Wipf","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1322918889","display_name":"United States Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889"]},{"id":"https://openalex.org/I2799886695","display_name":"Veterans Health Administration","ror":"https://ror.org/05eq41471","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"J E Wipf","raw_affiliation_strings":["Department of Medicine, Seattle Veterans Affairs Medical Center, WA 98108, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Seattle Veterans Affairs Medical Center, WA 98108, USA","institution_ids":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5088228151"],"corresponding_institution_ids":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"],"apc_list":null,"apc_paid":null,"fwci":0.608,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.68670713,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"163","issue":"2","first_page":"145","last_page":"52"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10065","display_name":"Atrial Fibrillation Management and Outcomes","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10065","display_name":"Atrial Fibrillation Management and Outcomes","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10285","display_name":"Venous Thromboembolism Diagnosis and Management","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/atrial-fibrillation","display_name":"atrial fibrillation","score":0.9739999771118164},{"id":"https://openalex.org/keywords/anticoagulation","display_name":"anticoagulation","score":0.972000002861023},{"id":"https://openalex.org/keywords/warfarin","display_name":"warfarin","score":0.9980000257492065},{"id":"https://openalex.org/keywords/thromboembolic-risk","display_name":"thromboembolic risk","score":0.8930000066757202},{"id":"https://openalex.org/keywords/bleeding-risk","display_name":"bleeding risk","score":0.7940000295639038},{"id":"https://openalex.org/keywords/valvular-atrial-fibrillation","display_name":"valvular atrial fibrillation","score":0.9070000052452087},{"id":"https://openalex.org/keywords/non-valvular-atrial-fibrillation","display_name":"non-valvular atrial fibrillation","score":0.9760000109672546},{"id":"https://openalex.org/keywords/stroke-prevention","display_name":"stroke prevention","score":0.824999988079071},{"id":"https://openalex.org/keywords/aspirin","display_name":"aspirin","score":0.9300000071525574},{"id":"https://openalex.org/keywords/lone-atrial-fibrillation","display_name":"lone atrial fibrillation","score":0.8899999856948853}],"concepts":[{"id":"https://openalex.org/C2779161974","wikidata":"https://www.wikidata.org/wiki/Q815819","display_name":"Atrial fibrillation","level":2,"score":0.933372974395752},{"id":"https://openalex.org/C2776301958","wikidata":"https://www.wikidata.org/wiki/Q407431","display_name":"Warfarin","level":3,"score":0.8951080441474915},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8910715579986572},{"id":"https://openalex.org/C2777628954","wikidata":"https://www.wikidata.org/wiki/Q18216","display_name":"Aspirin","level":2,"score":0.6763752698898315},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.6388770341873169},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6379035711288452},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.59006267786026},{"id":"https://openalex.org/C2777185221","wikidata":"https://www.wikidata.org/wiki/Q275466","display_name":"Embolism","level":2,"score":0.5439290404319763},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.44335585832595825},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000925","descriptor_name":"Anticoagulants","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D000925","descriptor_name":"Anticoagulants","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D002986","descriptor_name":"Clinical Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013923","descriptor_name":"Thromboembolism","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D013923","descriptor_name":"Thromboembolism","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D014859","descriptor_name":"Warfarin","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D014859","descriptor_name":"Warfarin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true}],"locations_count":4,"locations":[{"id":"pmh:oai:europepmc.org:196441","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1303009","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:7571562","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7571562","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Western journal of medicine","raw_type":"Case Reports"},{"id":"pmh:oai:pubmedcentral.nih.gov:1303009","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1303009/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"West J Med","raw_type":"Text"},{"id":"mag:201492055","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7571562","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:europepmc.org:196441","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1303009","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W1508099771","https://openalex.org/W1969547123","https://openalex.org/W1977057099","https://openalex.org/W1983807641","https://openalex.org/W1994894525","https://openalex.org/W2002107072","https://openalex.org/W2012331257","https://openalex.org/W2013832146","https://openalex.org/W2021065671","https://openalex.org/W2021265694","https://openalex.org/W2034478678","https://openalex.org/W2036623248","https://openalex.org/W2036803032","https://openalex.org/W2037256678","https://openalex.org/W2040452288","https://openalex.org/W2053535889","https://openalex.org/W2055819852","https://openalex.org/W2064428105","https://openalex.org/W2073041630","https://openalex.org/W2075580981","https://openalex.org/W2084719078","https://openalex.org/W2089419646","https://openalex.org/W2118654837","https://openalex.org/W2119473125","https://openalex.org/W2127211051","https://openalex.org/W2151184079","https://openalex.org/W2160781070","https://openalex.org/W2161283927","https://openalex.org/W2162131421","https://openalex.org/W2164393668","https://openalex.org/W2172069617","https://openalex.org/W2175936500","https://openalex.org/W2313681591","https://openalex.org/W2314364287","https://openalex.org/W2331274093","https://openalex.org/W2340349481","https://openalex.org/W2340516904","https://openalex.org/W2413022161","https://openalex.org/W4233049625","https://openalex.org/W4233753717","https://openalex.org/W4254193806"],"related_works":["https://openalex.org/W2414201401","https://openalex.org/W7099624878","https://openalex.org/W2079658449","https://openalex.org/W24061430","https://openalex.org/W2413921214","https://openalex.org/W2405541938","https://openalex.org/W158835408","https://openalex.org/W2443992936","https://openalex.org/W2414567023","https://openalex.org/W2164952493"],"abstract_inverted_index":{"The":[0],"thromboembolic":[1],"risk":[2,70,91],"of":[3,16,28,31,68,74,88,92],"atrial":[4,41,51,78,121],"fibrillation":[5,42,52,122],"varies":[6],"with":[7,50,71,119],"the":[8,69,72,90],"underlying":[9],"cause,":[10],"associated":[11],"heart":[12],"disease,":[13],"and":[14,33,43,53,80],"history":[15],"previous":[17,54],"embolism.":[18],"Decisions":[19],"regarding":[20],"warfarin":[21,75,96],"anticoagulation":[22,81],"therapy":[23,97,105],"require":[24,125],"a":[25,66,85],"careful":[26,86],"assessment":[27],"relative":[29],"risks":[30],"thromboembolism":[32],"bleeding.":[34],"Anticoagulation":[35],"is":[36,82,98,106],"strongly":[37],"indicated":[38],"for":[39],"valvular":[40],"to":[44,100],"prevent":[45],"recurrent":[46],"stroke":[47,55],"in":[48,76],"patients":[49],"or":[56],"transient":[57],"ischemic":[58],"attack.":[59],"Several":[60],"randomized":[61],"trials":[62],"have":[63],"consistently":[64],"shown":[65],"reduction":[67],"use":[73],"nonvalvular":[77],"fibrillation,":[79],"recommended.":[83],"With":[84],"selection":[87],"patients,":[89],"major":[93],"bleeding":[94],"on":[95],"2%":[99],"4%":[101],"per":[102],"year.":[103],"Aspirin":[104],"less":[107,111],"efficacious":[108],"but":[109],"also":[110],"risky":[112],"than":[113,117],"warfarin.":[114],"Patients":[115],"younger":[116],"60":[118],"lone":[120],"do":[123],"not":[124],"anticoagulation.":[126]},"counts_by_year":[],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}