{"id":"https://openalex.org/W2014899178","doi":"https://doi.org/10.1111/j.1600-0560.1988.tb00546.x","title":"Anti\u2010Leu 19 monoclonal antibody detects an antigen on autonomic nerves in human skin","display_name":"Anti\u2010Leu 19 monoclonal antibody detects an antigen on autonomic nerves in human skin","publication_year":1988,"publication_date":"1988-07-01","ids":{"openalex":"https://openalex.org/W2014899178","doi":"https://doi.org/10.1111/j.1600-0560.1988.tb00546.x","mag":"2014899178","pmid":"https://pubmed.ncbi.nlm.nih.gov/2460512"},"language":"en","primary_location":{"id":"doi:10.1111/j.1600-0560.1988.tb00546.x","doi":"https://doi.org/10.1111/j.1600-0560.1988.tb00546.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1600-0560.1988.tb00546.x","pdf_url":null,"source":{"id":"https://openalex.org/S92442678","display_name":"Journal of Cutaneous Pathology","issn_l":"0303-6987","issn":["0303-6987","1600-0560"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cutaneous Pathology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038546640","display_name":"H. W. Niedecken","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I135140700","display_name":"University of Bonn","ror":"https://ror.org/041nas322","country_code":"DE","type":"education","lineage":["https://openalex.org/I135140700"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"H. Niedecken","raw_affiliation_strings":["Department of Dermatology, University of Bonn, West Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, University of Bonn, West Germany","institution_ids":["https://openalex.org/I135140700"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110744432","display_name":"Wolfgang Wehrmann","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I135140700","display_name":"University of Bonn","ror":"https://ror.org/041nas322","country_code":"DE","type":"education","lineage":["https://openalex.org/I135140700"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"W. Wehrmann","raw_affiliation_strings":["Department of Dermatology, University of Bonn, West Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, University of Bonn, West Germany","institution_ids":["https://openalex.org/I135140700"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112061695","display_name":"Ralf Bauer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I135140700","display_name":"University of Bonn","ror":"https://ror.org/041nas322","country_code":"DE","type":"education","lineage":["https://openalex.org/I135140700"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"R. Bauer","raw_affiliation_strings":["Department of Dermatology, University of Bonn, West Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, University of Bonn, West Germany","institution_ids":["https://openalex.org/I135140700"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111835211","display_name":"H. W. Kreysel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I135140700","display_name":"University of Bonn","ror":"https://ror.org/041nas322","country_code":"DE","type":"education","lineage":["https://openalex.org/I135140700"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"H. W. Kreysel","raw_affiliation_strings":["Department of Dermatology, University of Bonn, West Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, University of Bonn, West Germany","institution_ids":["https://openalex.org/I135140700"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5038546640"],"corresponding_institution_ids":["https://openalex.org/I135140700"],"apc_list":{"value":3570,"currency":"USD","value_usd":3570},"apc_paid":null,"fwci":0.9246,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.69881306,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"15","issue":"4","first_page":"212","last_page":"214"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14134","display_name":"Classical Anatomy and Histology","score":0.5898000001907349,"subfield":{"id":"https://openalex.org/subfields/2702","display_name":"Anatomy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T14134","display_name":"Classical Anatomy and Histology","score":0.5898000001907349,"subfield":{"id":"https://openalex.org/subfields/2702","display_name":"Anatomy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11735","display_name":"Peripheral Neuropathies and Disorders","score":0.03620000183582306,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11650","display_name":"Skin and Cellular Biology Research","score":0.03350000083446503,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/natural-killer-cells","display_name":"natural killer cells","score":0.7049999833106995},{"id":"https://openalex.org/keywords/autonomic-nervous-system","display_name":"autonomic nervous system","score":0.7179999947547913},{"id":"https://openalex.org/keywords/skin-nerves","display_name":"skin nerves","score":0.6890000104904175},{"id":"https://openalex.org/keywords/sympathetic-innervation","display_name":"sympathetic innervation","score":0.7459999918937683},{"id":"https://openalex.org/keywords/sweat-glands","display_name":"sweat glands","score":0.746999979019165},{"id":"https://openalex.org/keywords/myelin-associated-glycoprotein","display_name":"myelin-associated glycoprotein","score":0.9869999885559082},{"id":"https://openalex.org/keywords/cutaneous-nerves","display_name":"cutaneous nerves","score":0.40799999237060547}],"concepts":[{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.6619476079940796},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.5788711309432983},{"id":"https://openalex.org/C2777372248","wikidata":"https://www.wikidata.org/wiki/Q171064","display_name":"Autonomic nervous system","level":4,"score":0.5674193501472473},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.5608913898468018},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.5406100749969482},{"id":"https://openalex.org/C2778040839","wikidata":"https://www.wikidata.org/wiki/Q243784","display_name":"Sweat gland","level":3,"score":0.5260854959487915},{"id":"https://openalex.org/C94487597","wikidata":"https://www.wikidata.org/wiki/Q11101","display_name":"Sensory system","level":2,"score":0.5139593482017517},{"id":"https://openalex.org/C545706735","wikidata":"https://www.wikidata.org/wiki/Q9404","display_name":"Nervous system","level":2,"score":0.5085090398788452},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4837629795074463},{"id":"https://openalex.org/C2778609137","wikidata":"https://www.wikidata.org/wiki/Q105790271","display_name":"Myelin","level":3,"score":0.46213072538375854},{"id":"https://openalex.org/C2776533406","wikidata":"https://www.wikidata.org/wiki/Q187215","display_name":"Sympathetic nervous system","level":3,"score":0.4560229480266571},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.45354074239730835},{"id":"https://openalex.org/C2777459323","wikidata":"https://www.wikidata.org/wiki/Q5259911","display_name":"Human skin","level":2,"score":0.4357563853263855},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.42664188146591187},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.422077476978302},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.28300148248672485},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2518322467803955},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.2511272430419922},{"id":"https://openalex.org/C63398376","wikidata":"https://www.wikidata.org/wiki/Q7395168","display_name":"SWEAT","level":2,"score":0.17786747217178345},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.11744412779808044},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.0},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000945","descriptor_name":"Antigens, Differentiation, T-Lymphocyte","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D001341","descriptor_name":"Autonomic Nervous System","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false},{"descriptor_ui":"D001341","descriptor_name":"Autonomic Nervous System","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009412","descriptor_name":"Nerve Fibers","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D009412","descriptor_name":"Nerve Fibers","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000294","qualifier_name":"innervation","is_major_topic":true},{"descriptor_ui":"D012871","descriptor_name":"Skin Diseases","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D019002","descriptor_name":"CD56 Antigen","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1600-0560.1988.tb00546.x","doi":"https://doi.org/10.1111/j.1600-0560.1988.tb00546.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1600-0560.1988.tb00546.x","pdf_url":null,"source":{"id":"https://openalex.org/S92442678","display_name":"Journal of Cutaneous Pathology","issn_l":"0303-6987","issn":["0303-6987","1600-0560"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cutaneous Pathology","raw_type":"journal-article"},{"id":"pmid:2460512","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2460512","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of cutaneous pathology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6240000128746033}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W1489850871","https://openalex.org/W1542501019","https://openalex.org/W1965004433","https://openalex.org/W1992000854","https://openalex.org/W2067796820","https://openalex.org/W2068900688","https://openalex.org/W2073006349","https://openalex.org/W2090244113","https://openalex.org/W2094105345","https://openalex.org/W2096428903","https://openalex.org/W2166915766"],"related_works":["https://openalex.org/W2166915766","https://openalex.org/W2029555701","https://openalex.org/W2026396965","https://openalex.org/W2151976296","https://openalex.org/W2748938322","https://openalex.org/W2321548031","https://openalex.org/W2983169349","https://openalex.org/W2101858552","https://openalex.org/W1968603447","https://openalex.org/W1980584604"],"abstract_inverted_index":{"The":[0,84],"monoclonal":[1],"antibody":[2,21],"anti-Leu":[3,65,105],"19":[4,106],"recognizes":[5],"the":[6,18,20,31,34,37,41,50,53,59,62,77,90,99,114,119],"NKH-1":[7],"antigen":[8],"of":[9,17,33,52,58,80,86,89,118],"active":[10],"natural":[11],"killer":[12],"cells.":[13],"In":[14],"immunohistological":[15],"preparations":[16],"skin,":[19],"reacts":[22],"with":[23],"cutaneous":[24,82],"nerves":[25],"and":[26,40],"labels":[27,67,98],"nerve":[28],"fibers":[29],"in":[30,76],"region":[32],"sweat":[35],"glands,":[36],"blood":[38],"vessels":[39],"hair":[42],"arrector":[43],"muscles.":[44],"This":[45],"staining":[46],"pattern":[47],"corresponds":[48],"to":[49,73,108],"distribution":[51],"autonomic":[54,115],"sympathetic":[55],"nervous":[56,102,116],"system":[57,117],"skin.":[60,120],"On":[61],"other":[63],"hand,":[64],"7":[66,97],"a":[68,110],"myelin-associated":[69],"glycoprotein":[70],"which":[71],"is":[72],"be":[74,94],"found":[75],"myelin":[78],"sheath":[79],"sensory":[81,101],"nerves.":[83],"reactivity":[85],"neural":[87],"structures":[88],"skin":[91],"can":[92],"thus":[93],"differentiated.":[95],"Anti-Leu":[96],"myelinated":[100],"system,":[103],"whereas":[104],"seems":[107],"constitute":[109],"new":[111],"marker":[112],"for":[113]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2016-06-24T00:00:00"}