{"id":"https://openalex.org/W2014887977","doi":"https://doi.org/10.1016/j.tiv.2009.04.002","title":"Mitochondrial toxicity of the phyotochemicals daphnetoxin and daphnoretin \u2013 Relevance for possible anti-cancer application","display_name":"Mitochondrial toxicity of the phyotochemicals daphnetoxin and daphnoretin \u2013 Relevance for possible anti-cancer application","publication_year":2009,"publication_date":"2009-04-10","ids":{"openalex":"https://openalex.org/W2014887977","doi":"https://doi.org/10.1016/j.tiv.2009.04.002","mag":"2014887977","pmid":"https://pubmed.ncbi.nlm.nih.gov/19362137"},"language":"en","primary_location":{"id":"doi:10.1016/j.tiv.2009.04.002","doi":"https://doi.org/10.1016/j.tiv.2009.04.002","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.tiv.2009.04.002","pdf_url":null,"source":{"id":"https://openalex.org/S39580544","display_name":"Toxicology in Vitro","issn_l":"0887-2333","issn":["0887-2333","1879-3177"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Toxicology in Vitro","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042863509","display_name":"C\u00e1tia V. Diogo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4394709155","display_name":"Centro de Neuroci\u00eancias e Biologia Celular","ror":"https://ror.org/01nzkd566","country_code":"PT","type":"facility","lineage":["https://openalex.org/I4394709155","https://openalex.org/I76903346"]},{"id":"https://openalex.org/I76903346","display_name":"University of Coimbra","ror":"https://ror.org/04z8k9a98","country_code":"PT","type":"education","lineage":["https://openalex.org/I76903346"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"C\u00e1tia V. Diogo","raw_affiliation_strings":["Department of Zoology, Center for Neurosciences and Cell Biology, University of Coimbra, 3004-517 Coimbra, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Zoology, Center for Neurosciences and Cell Biology, University of Coimbra, 3004-517 Coimbra, Portugal","institution_ids":["https://openalex.org/I4394709155","https://openalex.org/I76903346"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016694503","display_name":"Lu\u00eds Manuel F\u00e9lix","orcid":"https://orcid.org/0000-0001-9870-6666","observed_orcids":["https://orcid.org/0000-0001-9870-6666"]},"institutions":[{"id":"https://openalex.org/I155381812","display_name":"University of Tr\u00e1s-os-Montes and Alto Douro","ror":"https://ror.org/03qc8vh97","country_code":"PT","type":"education","lineage":["https://openalex.org/I155381812"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Lu\u00eds F\u00e9lix","raw_affiliation_strings":["Center for Animal and Veterinary Sciences, University of Tr\u00e1s-os-Montes and Alto Douro, Vila Real, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Animal and Veterinary Sciences, University of Tr\u00e1s-os-Montes and Alto Douro, Vila Real, Portugal","institution_ids":["https://openalex.org/I155381812"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064551979","display_name":"S\u00e9rgio M. F. Vilela","orcid":"https://orcid.org/0000-0001-5125-1676","observed_orcids":["https://orcid.org/0000-0001-5125-1676"]},"institutions":[{"id":"https://openalex.org/I155381812","display_name":"University of Tr\u00e1s-os-Montes and Alto Douro","ror":"https://ror.org/03qc8vh97","country_code":"PT","type":"education","lineage":["https://openalex.org/I155381812"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"S\u00e9rgio Vilela","raw_affiliation_strings":["Center for Animal and Veterinary Sciences, University of Tr\u00e1s-os-Montes and Alto Douro, Vila Real, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Animal and Veterinary Sciences, University of Tr\u00e1s-os-Montes and Alto Douro, Vila Real, Portugal","institution_ids":["https://openalex.org/I155381812"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016493548","display_name":"Ana Burgeiro","orcid":"https://orcid.org/0000-0001-8467-3840","observed_orcids":["https://orcid.org/0000-0001-8467-3840"]},"institutions":[{"id":"https://openalex.org/I76903346","display_name":"University of Coimbra","ror":"https://ror.org/04z8k9a98","country_code":"PT","type":"education","lineage":["https://openalex.org/I76903346"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Ana Burgeiro","raw_affiliation_strings":["Center for Neurosciences and Cell Biology, Department of Zoology, University of Coimbra, 3004-517 Coimbra, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Neurosciences and Cell Biology, Department of Zoology, University of Coimbra, 3004-517 Coimbra, Portugal","institution_ids":["https://openalex.org/I76903346"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030276853","display_name":"In\u00eas A. Barbosa","orcid":"https://orcid.org/0000-0001-8740-4523","observed_orcids":["https://orcid.org/0000-0001-8740-4523"]},"institutions":[{"id":"https://openalex.org/I76903346","display_name":"University of Coimbra","ror":"https://ror.org/04z8k9a98","country_code":"PT","type":"education","lineage":["https://openalex.org/I76903346"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"In\u00eas A. Barbosa","raw_affiliation_strings":["Center for Neurosciences and Cell Biology, Department of Zoology, University of Coimbra, 3004-517 Coimbra, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Neurosciences and Cell Biology, Department of Zoology, University of Coimbra, 3004-517 Coimbra, Portugal","institution_ids":["https://openalex.org/I76903346"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103856612","display_name":"Maria Jo\u00e3o M. Carvalho","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I155381812","display_name":"University of Tr\u00e1s-os-Montes and Alto Douro","ror":"https://ror.org/03qc8vh97","country_code":"PT","type":"education","lineage":["https://openalex.org/I155381812"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Maria J.M. Carvalho","raw_affiliation_strings":["Department of Chemistry, University of Tr\u00e1s-os-Montes and Alto Douro, Vila Real, Portugal","Department of Chemistry , University of Tras-os-Montes and Alto Douro , Vila Real, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Tr\u00e1s-os-Montes and Alto Douro, Vila Real, Portugal","institution_ids":["https://openalex.org/I155381812"]},{"raw_affiliation_string":"Department of Chemistry , University of Tras-os-Montes and Alto Douro , Vila Real, Portugal","institution_ids":["https://openalex.org/I155381812"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100747732","display_name":"Paulo Jorge Oliveira","orcid":"https://orcid.org/0000-0002-5201-9948","observed_orcids":["https://orcid.org/0000-0002-5201-9948"]},"institutions":[{"id":"https://openalex.org/I76903346","display_name":"University of Coimbra","ror":"https://ror.org/04z8k9a98","country_code":"PT","type":"education","lineage":["https://openalex.org/I76903346"]}],"countries":["PT"],"is_corresponding":true,"raw_author_name":"Paulo J. Oliveira","raw_affiliation_strings":["Center for Neurosciences and Cell Biology, Department of Zoology, University of Coimbra, 3004-517 Coimbra, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Neurosciences and Cell Biology, Department of Zoology, University of Coimbra, 3004-517 Coimbra, Portugal","institution_ids":["https://openalex.org/I76903346"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5036548685","display_name":"Francisco Peixoto","orcid":"https://orcid.org/0000-0001-9729-7477","observed_orcids":["https://orcid.org/0000-0001-9729-7477"]},"institutions":[{"id":"https://openalex.org/I155381812","display_name":"University of Tr\u00e1s-os-Montes and Alto Douro","ror":"https://ror.org/03qc8vh97","country_code":"PT","type":"education","lineage":["https://openalex.org/I155381812"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Francisco P. Peixoto","raw_affiliation_strings":["Center for Animal and Veterinary Sciences, University of Tr\u00e1s-os-Montes and Alto Douro, Vila Real, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Animal and Veterinary Sciences, University of Tr\u00e1s-os-Montes and Alto Douro, Vila Real, Portugal","institution_ids":["https://openalex.org/I155381812"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5100747732"],"corresponding_institution_ids":["https://openalex.org/I76903346"],"apc_list":{"value":4200,"currency":"USD","value_usd":4200},"apc_paid":null,"fwci":0.7691,"has_fulltext":false,"cited_by_count":42,"citation_normalized_percentile":{"value":0.6610854,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"23","issue":"5","first_page":"772","last_page":"779"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.8217999935150146,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.8217999935150146,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12530","display_name":"Bioactive Natural Diterpenoids Research","score":0.07240000367164612,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12356","display_name":"Bioactive Compounds and Antitumor Agents","score":0.017000000923871994,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/daphnoretin","display_name":"daphnoretin","score":1.0},{"id":"https://openalex.org/keywords/mitochondrial-toxicity","display_name":"mitochondrial toxicity","score":0.9520000219345093},{"id":"https://openalex.org/keywords/diterpenes","display_name":"diterpenoids","score":0.8059999942779541},{"id":"https://openalex.org/keywords/biscoumarins","display_name":"biscoumarins","score":0.9459999799728394},{"id":"https://openalex.org/keywords/thymelaeaceae","display_name":"Thymelaeaceae","score":0.9120000004768372},{"id":"https://openalex.org/keywords/anticancer-agents","display_name":"anticancer agents","score":0.7630000114440918},{"id":"https://openalex.org/keywords/mitochondrial-permeability-transition-pore","display_name":"mitochondrial permeability transition pore","score":0.8510000109672546},{"id":"https://openalex.org/keywords/proton-leak","display_name":"proton leak","score":0.7870000004768372},{"id":"https://openalex.org/keywords/atp-synthase-inhibition","display_name":"ATP synthase inhibition","score":0.9940000176429749},{"id":"https://openalex.org/keywords/mitochondrial-respiratory-chain-inhibition","display_name":"mitochondrial respiratory chain inhibition","score":0.8600000143051147},{"id":"https://openalex.org/keywords/cell-proliferation-inhibition","display_name":"cell proliferation inhibition","score":0.9169999957084656},{"id":"https://openalex.org/keywords/tumor-selectivity","display_name":"tumor selectivity","score":0.6140000224113464},{"id":"https://openalex.org/keywords/liver-mitochondria","display_name":"liver mitochondria","score":0.6909999847412109}],"concepts":[{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.7666799426078796},{"id":"https://openalex.org/C2777071529","wikidata":"https://www.wikidata.org/wiki/Q12796879","display_name":"Mitochondrial toxicity","level":3,"score":0.707804262638092},{"id":"https://openalex.org/C28859421","wikidata":"https://www.wikidata.org/wiki/Q39572","display_name":"Mitochondrion","level":2,"score":0.6693848371505737},{"id":"https://openalex.org/C13591479","wikidata":"https://www.wikidata.org/wiki/Q6881880","display_name":"Mitochondrial permeability transition pore","level":4,"score":0.5641263723373413},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4904772937297821},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.4756162762641907},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4429765045642853},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4420766234397888},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.42107701301574707},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.36377382278442383},{"id":"https://openalex.org/C31573885","wikidata":"https://www.wikidata.org/wiki/Q304484","display_name":"Programmed cell death","level":3,"score":0.2951813340187073},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.1766582727432251},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.1163596510887146},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000083162","descriptor_name":"Mitochondrial Permeability Transition Pore","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003374","descriptor_name":"Coumarins","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D003374","descriptor_name":"Coumarins","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D003374","descriptor_name":"Coumarins","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006576","descriptor_name":"Heterocyclic Compounds, 4 or More Rings","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D006576","descriptor_name":"Heterocyclic Compounds, 4 or More Rings","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D006576","descriptor_name":"Heterocyclic Compounds, 4 or More Rings","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D008545","descriptor_name":"Melanoma","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008856","descriptor_name":"Microscopy, Fluorescence","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008930","descriptor_name":"Mitochondria, Liver","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D008930","descriptor_name":"Mitochondria, Liver","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D025261","descriptor_name":"Mitochondrial Proton-Translocating ATPases","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D032364","descriptor_name":"Daphne","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D033681","descriptor_name":"Mitochondrial Membrane Transport Proteins","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D033681","descriptor_name":"Mitochondrial Membrane Transport Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D051336","descriptor_name":"Mitochondrial Membranes","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D051336","descriptor_name":"Mitochondrial Membranes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.tiv.2009.04.002","doi":"https://doi.org/10.1016/j.tiv.2009.04.002","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.tiv.2009.04.002","pdf_url":null,"source":{"id":"https://openalex.org/S39580544","display_name":"Toxicology in Vitro","issn_l":"0887-2333","issn":["0887-2333","1879-3177"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Toxicology in Vitro","raw_type":"journal-article"},{"id":"pmid:19362137","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19362137","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Toxicology in vitro : an international journal published in association with BIBRA","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W38084535","https://openalex.org/W57732670","https://openalex.org/W94390185","https://openalex.org/W1506043065","https://openalex.org/W1868190419","https://openalex.org/W1964509132","https://openalex.org/W1996733723","https://openalex.org/W1998101020","https://openalex.org/W2001875256","https://openalex.org/W2002232517","https://openalex.org/W2012308006","https://openalex.org/W2014179915","https://openalex.org/W2017732825","https://openalex.org/W2027437771","https://openalex.org/W2035838975","https://openalex.org/W2038221909","https://openalex.org/W2038784973","https://openalex.org/W2060605524","https://openalex.org/W2066403312","https://openalex.org/W2072610456","https://openalex.org/W2073776147","https://openalex.org/W2086095973","https://openalex.org/W2086320092","https://openalex.org/W2109689528","https://openalex.org/W2110877497","https://openalex.org/W2129968561","https://openalex.org/W2137951853","https://openalex.org/W2144095756","https://openalex.org/W2151923108","https://openalex.org/W2169925972","https://openalex.org/W2419442318","https://openalex.org/W2469965345","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W3140156404","https://openalex.org/W1964509132","https://openalex.org/W3147040131","https://openalex.org/W2937864222","https://openalex.org/W4382812100","https://openalex.org/W7154395187","https://openalex.org/W3106588733","https://openalex.org/W2059522811","https://openalex.org/W2978394171","https://openalex.org/W4213457294"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}